Quadriceps intramuscular fat fraction rather than muscle size is associated with knee osteoarthritis

Osteoarthritis and Cartilage

Volumn 22, Issue 2, 2014, Pages 226-234

  Kumar, D ^a   Karampinos, D C ^a,b   MacLeod, T D ^a   Lin, W ^a   Nardo, L ^a   Li, X ^a   Link, T M ^a   Majumdar, S ^a   Souza, R B ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b TECHNICAL UNIVERSITY OF MUNICH   (Germany)

Author keywords

Cartilage; Hamstrings; Quadriceps strength; Water fat imaging

Indexed keywords

ADULT; AGING; ARTICLE; CARTILAGE INJURY; CONTROLLED STUDY; FAT MASS; FEMALE; HUMAN; INTRAMUSCULAR FAT FRACTION; KNEE MENISCUS RUPTURE; KNEE OSTEOARTHRITIS; MAJOR CLINICAL STUDY; MALE; MIDDLE AGED; MUSCLE FUNCTION; MUSCLE MASS; MUSCLE STRENGTH; NUCLEAR MAGNETIC RESONANCE IMAGING; NUCLEAR MAGNETIC RESONANCE SCANNER; OBESITY; PREDICTIVE VALUE; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE; QUADRICEPS FEMORIS MUSCLE; SCORING SYSTEM; SELF REPORT; THIGH;

CARTILAGE; HAMSTRINGS; QUADRICEPS STRENGTH; WATER/FAT IMAGING;

ADIPOSE TISSUE; ADIPOSITY; ADULT; AGED; AGING; CARTILAGE, ARTICULAR; CASE-CONTROL STUDIES; EXERCISE TEST; FEMALE; HUMANS; MAGNETIC RESONANCE IMAGING; MALE; MIDDLE AGED; MUSCLE STRENGTH; OSTEOARTHRITIS, KNEE; QUADRICEPS MUSCLE; SEVERITY OF ILLNESS INDEX; TENDONS; THIGH;

EID: 84893796972     PISSN: 10634584     EISSN: 15229653     Source Type: Journal    
DOI: 10.1016/j.joca.2013.12.005     Document Type: Article

References (50)

1. Roemer F.W., Crema M.D., Trattnig S., Guermazi A. Advances in imaging of osteoarthritis and cartilage. Radiology 2011, 260:332-354.
2. Yusuf E., Nelissen R.G., Ioan-Facsinay A., Stojanovic-Susulic V., DeGroot J., van Osch G., et al. Association between weight or body mass index and hand osteoarthritis: a systematic review. Ann Rheum Dis 2010, 69:761-765.
3. Goodpaster B.H., Carlson C.L., Visser M., Kelley D.E., Scherzinger A., Harris T.B., et al. Attenuation of skeletal muscle and strength in the elderly: the Health ABC Study. JAppl Physiol 2001, 90:2157-2165.
4. Visser M., Kritchevsky S.B., Goodpaster B.H., Newman A.B., Nevitt M., Stamm E., et al. Leg muscle mass and composition in relation to lower extremity performance in men and women aged 70 to 79: the health, aging and body composition study. JAm Geriatr Soc 2002, 50:897-904.
5. Durheim M.T., Slentz C.A., Bateman L.A., Mabe S.K., Kraus W.E. Relationships between exercise-induced reductions in thigh intermuscular adipose tissue, changes in lipoprotein particle size, and visceral adiposity. Am J Physiol Endocrinol Metab 2008, 295:E407-E412.
6. Blumenfeld O., Williams F.M., Hart D.J., Arden N.K., Spector T.D., Livshits G. Lower limbs composition and radiographic knee osteoarthritis (RKOA) in Chingford sample - a longitudinal study. Arch Gerontol Geriatr 2013, 56:148-154.
7. Conroy M.B., Kwoh C.K., Krishnan E., Nevitt M.C., Boudreau R., Carbone L.D., et al. Muscle strength, mass, and quality in older men and women with knee osteoarthritis. Arthritis Care Res (Hoboken) 2012, 64:15-21.
8. Maly M.R., Calder K.M., Macintyre N.J., Beattie K.A. Relationship of intermuscular fat volume in the thigh with knee extensor strength and physical performance in women at risk of or with knee osteoarthritis. Arthritis Care Res (Hoboken) 2013, 65:44-52.
9. Goodpaster B.H., Stenger V.A., Boada F., McKolanis T., Davis D., Ross R., et al. Skeletal muscle lipid concentration quantified by magnetic resonance imaging. Am J Clin Nutr 2004, 79:748-754.
10. Schick F., Machann J., Brechtel K., Strempfer A., Klumpp B., Stein D.T., et al. MRI of muscular fat. Magn Reson Med 2002, 47:720-727.
11. Vettor R., Milan G., Franzin C., Sanna M., De Coppi P., Rizzuto R., et al. The origin of intermuscular adipose tissue and its pathophysiological implications. Am J Physiol Endocrinol Metab 2009, 297:E987-E998.
12. Dixon W.T. Simple proton spectroscopic imaging. Radiology 1984, 153:189-194.
13. Glover G.H., Schneider E. Three-point Dixon technique for true water/fat decomposition with B0 inhomogeneity correction. Magn Reson Med 1991, 18:371-383.
14. Reeder S.B., Pineda A.R., Wen Z., Shimakawa A., Yu H., Brittain J.H., et al. Iterative decomposition of water and fat with echo asymmetry and least-squares estimation (IDEAL): application with fast spin-echo imaging. Magn Reson Med 2005, 54:636-644.
15. Yu H., Shimakawa A., McKenzie C.A., Brodsky E., Brittain J.H., Reeder S.B. Multiecho water-fat separation and simultaneous R2* estimation with multifrequency fat spectrum modeling. Magn Reson Med 2008, 60:1122-1134.
16. Meisamy S., Hines C.D., Hamilton G., Sirlin C.B., McKenzie C.A., Yu H., et al. Quantification of hepatic steatosis with T1-independent, T2-corrected MR imaging with spectral modeling of fat: blinded comparison with MR spectroscopy. Radiology 2011, 258:767-775.
17. Karampinos D.C., Baum T., Nardo L., Alizai H., Yu H., Carballido-Gamio J., et al. Characterization of the regional distribution of skeletal muscle adipose tissue in type 2 diabetes using chemical shift-based water/fat separation. JMagn Reson Imaging 2012, 35:899-907.
18. Nardo L., Karampinos D.C., Krug R. Quantitative assessment of fat infiltration in the rotator cuff muscles using water-fat MRI. JMagn Reson Imaging 2013 Sep 24, 10.1002/jmri.24278.
19. Alizai H., Nardo L., Karampinos D.C., Joseph G.B., Yap S.P., Baum T., et al. Comparison of clinical semi-quantitative assessment of muscle fat infiltration with quantitative assessment using chemical shift-based water/fat separation in MR studies of the calf of post-menopausal women. Eur Radiol 2012, 22:1592-1600.
20. Petterson S.C., Barrance P., Buchanan T., Binder-Macleod S., Snyder-Mackler L. Mechanisms underlying quadriceps weakness in knee osteoarthritis. Med Sci Sports Exerc 2008, 40:422-427.
21. Menashe L., Hirko K., Losina E., Kloppenburg M., Zhang W., Li L., et al. The diagnostic performance of MRI in osteoarthritis: a systematic review and meta-analysis. Osteoarthritis Cartilage 2011, 20:13-21.
22. Altman R., Asch E., Bloch D., Bole G., Borenstein D., Brandt K., et al. Development of criteria for the classification and reporting of osteoarthritis. Classification of osteoarthritis of the knee. Diagnostic and Therapeutic Criteria Committee of the American Rheumatism Association. Arthritis Rheum 1986, 29:1039-1049.
23. Charles H.C., Kraus V.B., Ainslie M., Hellio Le Graverand-Gastineau M.P. Optimization of the fixed-flexion knee radiograph. Osteoarthritis Cartilage 2007, 15:1221-1224.
24. Kellgren J.H., Lawrence J.S. Radiological assessment of osteo-arthrosis. Ann Rheum Dis 1957, 16:494-502.
25. Reeder S.B., McKenzie C.A., Pineda A.R., Yu H., Shimakawa A., Brau A.C., et al. Water-fat separation with IDEAL gradient-echo imaging. JMagn Reson Imaging 2007, 25:644-652.
26. Joseph G.B., Baum T., Alizai H., Carballido-Gamio J., Nardo L., Virayavanich W., et al. Baseline mean and heterogeneity of MR cartilage T2 are associated with morphologic degeneration of cartilage, meniscus, and bone marrow over 3 years - data from the Osteoarthritis Initiative. Osteoarthritis Cartilage 2012, 20:727-735.
27. Stahl R., Luke A., Ma C.B., Krug R., Steinbach L., Majumdar S., et al. Prevalence of pathologic findings in asymptomatic knees of marathon runners before and after a competition in comparison with physically active subjects - a 3.0T magnetic resonance imaging study. Skeletal Radiol 2008, 37:627-638.
28. Peterfy C.G., Guermazi A., Zaim S., Tirman P.F., Miaux Y., White D., et al. Whole-organ magnetic resonance imaging score (WORMS) of the knee in osteoarthritis. Osteoarthritis Cartilage 2004, 12:177-190.
29. Valentinitsch A., Karampinos D.C., Alizai H., Subburaj K., Kumar D., Link T.M., et al. Automated unsupervised multi-parametric classification of adipose tissue depots in skeletal muscle. JMagn Reson Imaging 2013, 37:917-927.
30. Roos E.M., Roos H.P., Lohmander L.S., Ekdahl C., Beynnon B.D. Knee Injury and Osteoarthritis Outcome Score (KOOS) - development of a self-administered outcome measure. JOrthop Sports Phys Ther 1998, 28:88-96.
31. Liang M.H., Larson M.G., Cullen K.E., Schwartz J.A. Comparative measurement efficiency and sensitivity of five health status instruments for arthritis research. Arthritis Rheum 1985, 28:542-547.
32. Rejeski W.J., Ettinger W.H., Schumaker S., James P., Burns R., Elam J.T. Assessing performance-related disability in patients with knee osteoarthritis. Osteoarthritis Cartilage 1995, 3:157-167.
33. Kennedy D.M., Stratford P.W., Wessel J., Gollish J.D., Penney D. Assessing stability and change of four performance measures: a longitudinal study evaluating outcome following total hip and knee arthroplasty. BMC Musculoskelet Disord 2005, 6:3.
34. Field A. Discovering Statistics Using SPSS 2005, Sage Publications Ltd, London, UK. 2nd edn.
35. Sattler M., Dannhauer T., Hudelmaier M., Wirth W., Sanger A.M., Kwoh C.K., et al. Side differences of thigh muscle cross-sectional areas and maximal isometric muscle force in bilateral knees with the same radiographic disease stage, but unilateral frequent pain - data from the osteoarthritis initiative. Osteoarthritis Cartilage 2012, 20:532-540.
36. Goodpaster B.H., Krishnaswami S., Resnick H., Kelley D.E., Haggerty C., Harris T.B., et al. Association between regional adipose tissue distribution and both type 2 diabetes and impaired glucose tolerance in elderly men and women. Diabetes Care 2003, 26:372-379.
37. Yim J.E., Heshka S., Albu J., Heymsfield S., Kuznia P., Harris T., et al. Intermuscular adipose tissue rivals visceral adipose tissue in independent associations with cardiovascular risk. Int J Obes (Lond) 2007, 31:1400-1405.
38. Heilbronn L., Smith S.R., Ravussin E. Failure of fat cell proliferation, mitochondrial function and fat oxidation results in ectopic fat storage, insulin resistance and type II diabetes mellitus. Int J Obes Relat Metab Disord 2004, 28(Suppl 4):S12-S21.
39. Nieves D.J., Cnop M., Retzlaff B., Walden C.E., Brunzell J.D., Knopp R.H., et al. The atherogenic lipoprotein profile associated with obesity and insulin resistance is largely attributable to intra-abdominal fat. Diabetes 2003, 52:172-179.
40. Marcus R.L., Addison O., Kidde J.P., Dibble L.E., Lastayo P.C. Skeletal muscle fat infiltration: impact of age, inactivity, and exercise. JNutr Health Aging 2010, 14:362-366.
41. Taaffe D.R., Henwood T.R., Nalls M.A., Walker D.G., Lang T.F., Harris T.B. Alterations in muscle attenuation following detraining and retraining in resistance-trained older adults. Gerontology 2009, 55:217-223.
42. Ruhdorfer A., Dannhauer T., Wirth W., Hitzl W., Kwoh C.K., Guermazi A., et al. Thigh muscle cross-sectional areas and strength in advanced versus early painful osteoarthritis: an exploratory between-knee, within-person comparison in osteoarthritis initiative participants. Arthritis Care Res (Hoboken) 2013, 65:1034-1042.
43. Ikeda S., Tsumura H., Torisu T. Age-related quadriceps-dominant muscle atrophy and incident radiographic knee osteoarthritis. JOrthop Sci 2005, 10:121-126.
44. Fink B., Egl M., Singer J., Fuerst M., Bubenheim M., Neuen-Jacob E. Morphologic changes in the vastus medialis muscle in patients with osteoarthritis of the knee. Arthritis Rheum 2007, 56:3626-3633.
45. Hassan B.S., Doherty S.A., Mockett S., Doherty M. Effect of pain reduction on postural sway, proprioception, and quadriceps strength in subjects with knee osteoarthritis. Ann Rheum Dis 2002, 61:422-428.
46. Torry M.R., Decker M.J., Viola R.W., O'Connor D.D., Steadman J.R. Intra-articular knee joint effusion induces quadriceps avoidance gait patterns. Clin Biomech (Bristol, Avon) 2000, 15:147-159.
47. Kubo K., Tsunoda N., Kanehisa H., Fukunaga T. Activation of agonist and antagonist muscles at different joint angles during maximal isometric efforts. Eur J Appl Physiol 2004, 91:349-352.
48. Goutallier D., Postel J.M., Bernageau J., Lavau L., Voisin M.C. Fatty muscle degeneration in cuff ruptures. Pre- and postoperative evaluation by CT scan. Clin Orthop Relat Res 1994, 78-83.
49. Beattie K.A., MacIntyre N.J., Ramadan K., Inglis D., Maly M.R. Longitudinal changes in intermuscular fat volume and quadriceps muscle volume in the thighs of women with knee osteoarthritis. Arthritis Care Res (Hoboken) 2012, 64:22-29.
50. NSBRI. Predicting Height from the Length of Limb Bones http://www.nsbri.org/humanphysspace/focus6/student1.html.