Viral clearance by flow-through mode ion exchange columns and membrane adsorbers

Biotechnology Progress

Volumn 30, Issue 1, 2014, Pages 124-131

  Miesegaes, G R ^a   Lute, S C ^a   Read, E K ^a   Brorson, K A ^a  

^a CENTER FOR DRUG EVALUATION AND RESEARCH   (United States)

Author keywords

Anion exchange chromatography; Design of experiments; DoE; Downstream purification; Membrane adsorbers; Monoclonal antibodies; Viral clearance

Indexed keywords

ADSORBERS; ANION EXCHANGE CHROMATOGRAPHY; DOE; DOWNSTREAM PURIFICATIONS; VIRAL CLEARANCE;

ADSORPTION; CELL CULTURE; CHROMATOGRAPHY; DESIGN OF EXPERIMENTS; MONOCLONAL ANTIBODIES; RESINS; SURFACE PLASMON RESONANCE; VIRUSES;

PURIFICATION;

METHAMPHETAMINE; MONOCLONAL ANTIBODY; RECOMBINANT PROTEIN;

ANION EXCHANGE CHROMATOGRAPHY; ARTICLE; ARTIFICIAL MEMBRANE; BIOTECHNOLOGY; DESIGN-OF-EXPERIMENTS; DOWNSTREAM PURIFICATION; EQUIPMENT; FACTUAL DATABASE; ION EXCHANGE CHROMATOGRAPHY; ISOLATION AND PURIFICATION; MEMBRANE ADSORBERS; METHODOLOGY; STANDARD; VIRAL CLEARANCE; VIRUS;

ANION EXCHANGE CHROMATOGRAPHY; DESIGN-OF-EXPERIMENTS; DOE; DOWNSTREAM PURIFICATION; MEMBRANE ADSORBERS; MONOCLONAL ANTIBODIES; VIRAL CLEARANCE;

ANTIBODIES, MONOCLONAL; BIOTECHNOLOGY; CHROMATOGRAPHY, ION EXCHANGE; DATABASES, FACTUAL; MEMBRANES, ARTIFICIAL; RECOMBINANT PROTEINS; VIRUSES;

EID: 84893786829     PISSN: 87567938     EISSN: 15206033     Source Type: Journal    
DOI: 10.1002/btpr.1832     Document Type: Article

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