-
1
-
-
0037150728
-
Src in cancer: deregulation and consequences for cell behaviour
-
Frame M.C. Src in cancer: deregulation and consequences for cell behaviour. Biochim Biophys Acta 2002, 1602:114-130.
-
(2002)
Biochim Biophys Acta
, vol.1602
, pp. 114-130
-
-
Frame, M.C.1
-
2
-
-
2942618768
-
A renaissance for SRC
-
Yeatman T.J. A renaissance for SRC. Nat Rev Cancer 2004, 4:470-480.
-
(2004)
Nat Rev Cancer
, vol.4
, pp. 470-480
-
-
Yeatman, T.J.1
-
3
-
-
0031439247
-
Cellular functions regulated by Src family kinases
-
Thomas S.M., Brugge J.S. Cellular functions regulated by Src family kinases. Annu Rev Cell Dev Biol 1997, 13:513-609.
-
(1997)
Annu Rev Cell Dev Biol
, vol.13
, pp. 513-609
-
-
Thomas, S.M.1
Brugge, J.S.2
-
4
-
-
0036270145
-
V-Src's hold over actin and cell adhesions
-
Frame M.C., Fincham V.J., Carragher N.O., Wyke J.A. v-Src's hold over actin and cell adhesions. Nat Rev Mol Cell Biol 2002, 3:233-245.
-
(2002)
Nat Rev Mol Cell Biol
, vol.3
, pp. 233-245
-
-
Frame, M.C.1
Fincham, V.J.2
Carragher, N.O.3
Wyke, J.A.4
-
5
-
-
17444374230
-
Src kinase regulation by phosphorylation and dephosphorylation
-
Roskoski R. Src kinase regulation by phosphorylation and dephosphorylation. Biochem Biophys Res Commun 2005, 331:1-14.
-
(2005)
Biochem Biophys Res Commun
, vol.331
, pp. 1-14
-
-
Roskoski, R.1
-
6
-
-
34547199651
-
Clinical relevance of targeted interference with Src-mediated signal transduction events
-
Ly Q.P., Yeatman T.J. Clinical relevance of targeted interference with Src-mediated signal transduction events. Recent Results Cancer Res 2007, 172:169-188.
-
(2007)
Recent Results Cancer Res
, vol.172
, pp. 169-188
-
-
Ly, Q.P.1
Yeatman, T.J.2
-
7
-
-
15844365555
-
Modulation of the SH2 binding specificity and kinase activity of Src by tyrosine phosphorylation within its SH2 domain
-
Stover D.R., Furet P., Lydon N.B. Modulation of the SH2 binding specificity and kinase activity of Src by tyrosine phosphorylation within its SH2 domain. J Biol Chem 1996, 271:12481-12487.
-
(1996)
J Biol Chem
, vol.271
, pp. 12481-12487
-
-
Stover, D.R.1
Furet, P.2
Lydon, N.B.3
-
8
-
-
0035030510
-
SH3 domains: complexity in moderation
-
Mayer B.J. SH3 domains: complexity in moderation. J Cell Sci 2001, 114:1253-1263.
-
(2001)
J Cell Sci
, vol.114
, pp. 1253-1263
-
-
Mayer, B.J.1
-
9
-
-
73549112454
-
Is expression or activation of Src kinase associated with cancer-specific survival in ER-, PR- and HER2-negative breast cancer patients
-
Elsberger B., Tan B.A., Mitchell T.J., et al. Is expression or activation of Src kinase associated with cancer-specific survival in ER-, PR- and HER2-negative breast cancer patients. Am J Pathol 2009, 175:1389-1397.
-
(2009)
Am J Pathol
, vol.175
, pp. 1389-1397
-
-
Elsberger, B.1
Tan, B.A.2
Mitchell, T.J.3
-
10
-
-
0034693806
-
Selected glimpses into the activation and function of Src kinase
-
Bjorge J.D., Jakymiw A., Fujita D.J. Selected glimpses into the activation and function of Src kinase. Oncogene 2000, 19:5620-5635.
-
(2000)
Oncogene
, vol.19
, pp. 5620-5635
-
-
Bjorge, J.D.1
Jakymiw, A.2
Fujita, D.J.3
-
11
-
-
0036674501
-
Dissemination and growth of cancer cells in metastatic sites
-
Chambers A.F., Groom A.C., MacDonald I.C. Dissemination and growth of cancer cells in metastatic sites. Nat Rev Cancer 2002, 2:563-572.
-
(2002)
Nat Rev Cancer
, vol.2
, pp. 563-572
-
-
Chambers, A.F.1
Groom, A.C.2
MacDonald, I.C.3
-
12
-
-
67649311599
-
Latent bone metastasis in breast cancer tied to Src-dependent survival signals
-
Zhang X.H., Wang Q., Gerald W., et al. Latent bone metastasis in breast cancer tied to Src-dependent survival signals. Cancer Cell 2009, 16:67-78.
-
(2009)
Cancer Cell
, vol.16
, pp. 67-78
-
-
Zhang, X.H.1
Wang, Q.2
Gerald, W.3
-
13
-
-
77956430031
-
Breast cancer patients' clinical outcome measures are associated with Src kinase family member expression
-
Elsberger B., Fullerton R., Zino S., et al. Breast cancer patients' clinical outcome measures are associated with Src kinase family member expression. Br J Cancer 2010, 103:899-909.
-
(2010)
Br J Cancer
, vol.103
, pp. 899-909
-
-
Elsberger, B.1
Fullerton, R.2
Zino, S.3
-
14
-
-
0030474489
-
C-Src protein expression is increased in human breast cancer. An immunohistochemical and biochemical analysis
-
Verbeek B.S., Vroom T.M., Adriaansen-Slot S.S., et al. c-Src protein expression is increased in human breast cancer. An immunohistochemical and biochemical analysis. J Pathol 1996, 180:383-388.
-
(1996)
J Pathol
, vol.180
, pp. 383-388
-
-
Verbeek, B.S.1
Vroom, T.M.2
Adriaansen-Slot, S.S.3
-
15
-
-
79959362334
-
Clinicopathological significance of Y416Src and Y527Src expression in breast cancer
-
Kanomata N., Kurebayashi J., Kozuka Y., Sonoo H., Moriya T. Clinicopathological significance of Y416Src and Y527Src expression in breast cancer. J Clin Pathol 2011, 64:578-586.
-
(2011)
J Clin Pathol
, vol.64
, pp. 578-586
-
-
Kanomata, N.1
Kurebayashi, J.2
Kozuka, Y.3
Sonoo, H.4
Moriya, T.5
-
16
-
-
34548701082
-
Dasatinib, an orally active small molecule inhibitor of both the Src and Abl kinases, selectively inhibits growth of basal-type/triple-negative breast cancer cell lines growing in vitro
-
Finn R.S., Dering J., Ginther C., et al. Dasatinib, an orally active small molecule inhibitor of both the Src and Abl kinases, selectively inhibits growth of basal-type/triple-negative breast cancer cell lines growing in vitro. Breast Cancer Res Treat 2007, 105:319-326.
-
(2007)
Breast Cancer Res Treat
, vol.105
, pp. 319-326
-
-
Finn, R.S.1
Dering, J.2
Ginther, C.3
-
17
-
-
56749185425
-
Phosphorylated c-Src in the nucleus is associated with improved patient outcome in ER-positive breast cancer
-
Campbell E.J., McDuff E., Tatarov O., et al. Phosphorylated c-Src in the nucleus is associated with improved patient outcome in ER-positive breast cancer. Br J Cancer 2008, 99:1769-1774.
-
(2008)
Br J Cancer
, vol.99
, pp. 1769-1774
-
-
Campbell, E.J.1
McDuff, E.2
Tatarov, O.3
-
18
-
-
85046914922
-
Elevated Src kinase activity attenuates Tamoxifen response in vitro and is associated with poor prognosis clinically
-
Morgan L., Gee J., Pumford S., et al. Elevated Src kinase activity attenuates Tamoxifen response in vitro and is associated with poor prognosis clinically. Cancer Biol Ther 2009, 8:1550-1580.
-
(2009)
Cancer Biol Ther
, vol.8
, pp. 1550-1580
-
-
Morgan, L.1
Gee, J.2
Pumford, S.3
-
19
-
-
84858741454
-
Subcellular localization of total and activated Src kinase in African American and Caucasian breast cancer
-
Anbalagan M., Moroz K., Ali A., Carrier L., Glodowski S., Rowan B.G. Subcellular localization of total and activated Src kinase in African American and Caucasian breast cancer. PLoS One 2012, 7:e33017.
-
(2012)
PLoS One
, vol.7
-
-
Anbalagan, M.1
Moroz, K.2
Ali, A.3
Carrier, L.4
Glodowski, S.5
Rowan, B.G.6
-
20
-
-
84868330508
-
Activation of rapid oestrogen signalling in aggressive human breast cancers
-
Poulard C., Treilleux I., Lavergne E., et al. Activation of rapid oestrogen signalling in aggressive human breast cancers. EMBO Mol Med 2012, 4:1200-1213.
-
(2012)
EMBO Mol Med
, vol.4
, pp. 1200-1213
-
-
Poulard, C.1
Treilleux, I.2
Lavergne, E.3
-
21
-
-
31044447246
-
Role of c-Src and focal adhesion kinase in progression and metastasis of estrogen receptor-positive breast cancer
-
Planas-Silva M.D. Role of c-Src and focal adhesion kinase in progression and metastasis of estrogen receptor-positive breast cancer. Biochem Biophys Res Commun 2006, 341:73-81.
-
(2006)
Biochem Biophys Res Commun
, vol.341
, pp. 73-81
-
-
Planas-Silva, M.D.1
-
22
-
-
84857048945
-
Shorter disease-specific survival of ER-positive breast cancer patients with high cytoplasmic Src kinase expression after tamoxifen treatment
-
Elsberger B., Paravasthu D.M., Tovey S.M., Edwards J. Shorter disease-specific survival of ER-positive breast cancer patients with high cytoplasmic Src kinase expression after tamoxifen treatment. J Cancer Res Clin Oncol 2012, 138:327-332.
-
(2012)
J Cancer Res Clin Oncol
, vol.138
, pp. 327-332
-
-
Elsberger, B.1
Paravasthu, D.M.2
Tovey, S.M.3
Edwards, J.4
-
23
-
-
84862829884
-
C-Src expression is predictive of poor prognosis in breast cancer patients with bone metastasis, but not in patients with visceral metastasis
-
Zhang L., Teng Y., Zhang Y., et al. c-Src expression is predictive of poor prognosis in breast cancer patients with bone metastasis, but not in patients with visceral metastasis. AMPIS 2012, 120:549-557.
-
(2012)
AMPIS
, vol.120
, pp. 549-557
-
-
Zhang, L.1
Teng, Y.2
Zhang, Y.3
-
24
-
-
80052860747
-
Phase II trial of dasatinib in patients with metastatic breast cancer using real-time pharmacodynamic tissue biomarkers of Src inhibition to escalate dosing
-
Herold C.I., Chadaram V., Peterson B.L., et al. Phase II trial of dasatinib in patients with metastatic breast cancer using real-time pharmacodynamic tissue biomarkers of Src inhibition to escalate dosing. Clin Cancer Res 2011, 17:6061-6070.
-
(2011)
Clin Cancer Res
, vol.17
, pp. 6061-6070
-
-
Herold, C.I.1
Chadaram, V.2
Peterson, B.L.3
-
25
-
-
80455173400
-
Dasatinib as a single agent in triple-negative breast cancer: results of an open-label phase 2 study
-
Finn R.S., Bengala C., Ibrahim N., et al. Dasatinib as a single agent in triple-negative breast cancer: results of an open-label phase 2 study. Clin Cancer Res 2011, 17:6905-6913.
-
(2011)
Clin Cancer Res
, vol.17
, pp. 6905-6913
-
-
Finn, R.S.1
Bengala, C.2
Ibrahim, N.3
-
26
-
-
84867891436
-
Targeted agents to reverse resistance to endocrine therapy in metastatic breast cancer: where are we now and where are we going
-
Fedele P., Calvani N., Marino A., et al. Targeted agents to reverse resistance to endocrine therapy in metastatic breast cancer: where are we now and where are we going. Crit Rev Oncol Hematol 2012, 84:243-251.
-
(2012)
Crit Rev Oncol Hematol
, vol.84
, pp. 243-251
-
-
Fedele, P.1
Calvani, N.2
Marino, A.3
-
27
-
-
0036890288
-
Activation of c-Src is inversely correlated with biological aggressiveness of breast carcinoma
-
Ito Y., Kawakatsu H., Takeda T., et al. Activation of c-Src is inversely correlated with biological aggressiveness of breast carcinoma. Breast Cancer Res Treat 2002, 76:261-267.
-
(2002)
Breast Cancer Res Treat
, vol.76
, pp. 261-267
-
-
Ito, Y.1
Kawakatsu, H.2
Takeda, T.3
-
28
-
-
78649990525
-
Is there an association with phosphorylation and dephosphorylation of Src kinase at tyrosine 530 and breast cancer patient disease-specific survival
-
Elsberger B., Tan B.A., Mallon E.A., Brunton V.G., Edwards J. Is there an association with phosphorylation and dephosphorylation of Src kinase at tyrosine 530 and breast cancer patient disease-specific survival. Br J Cancer 2010, 103:1831-1834.
-
(2010)
Br J Cancer
, vol.103
, pp. 1831-1834
-
-
Elsberger, B.1
Tan, B.A.2
Mallon, E.A.3
Brunton, V.G.4
Edwards, J.5
-
29
-
-
0030006232
-
A new monoclonal antibody which selectively recognizes the active form of Src tyrosine kinase
-
Kawakatsu H., Sakai T., Takagaki Y., et al. A new monoclonal antibody which selectively recognizes the active form of Src tyrosine kinase. J Biol Chem 1996, 271:5680-5685.
-
(1996)
J Biol Chem
, vol.271
, pp. 5680-5685
-
-
Kawakatsu, H.1
Sakai, T.2
Takagaki, Y.3
-
30
-
-
0033890195
-
Regulation of both apoptosis and cell survival by the v-Src oncoprotein
-
Johnson D., Agochiya M., Samejima K., Earnshaw W., Frame M., Wyke J. Regulation of both apoptosis and cell survival by the v-Src oncoprotein. Cell Death Differ 2000, 7(8):685-696.
-
(2000)
Cell Death Differ
, vol.7
, Issue.8
, pp. 685-696
-
-
Johnson, D.1
Agochiya, M.2
Samejima, K.3
Earnshaw, W.4
Frame, M.5
Wyke, J.6
-
31
-
-
67349267711
-
Redox regulation of anoikis resistance of metastatic prostate cancer cells: key role for Src and EGFR-mediated pro-survival signals
-
Giannoni E., Fiaschi T., Ramponi G., Chiarugi P. Redox regulation of anoikis resistance of metastatic prostate cancer cells: key role for Src and EGFR-mediated pro-survival signals. Oncogene 2009, 28(20):2074-2086.
-
(2009)
Oncogene
, vol.28
, Issue.20
, pp. 2074-2086
-
-
Giannoni, E.1
Fiaschi, T.2
Ramponi, G.3
Chiarugi, P.4
-
33
-
-
7244247062
-
Endothelial barrier disruption by VEGF-mediated Src activity potentiates tumor cell extravasation and metastasis
-
Weis S., Cui J., Barnes L., Cheresh D. Endothelial barrier disruption by VEGF-mediated Src activity potentiates tumor cell extravasation and metastasis. J Cell Biol 2004, 167(2):223-229.
-
(2004)
J Cell Biol
, vol.167
, Issue.2
, pp. 223-229
-
-
Weis, S.1
Cui, J.2
Barnes, L.3
Cheresh, D.4
-
34
-
-
13544252467
-
Tumor metastasis but not tumor growth is dependent on Src-mediated vascular permeability
-
Criscuoli M.L., Nguyen M., Eliceiri B.P. Tumor metastasis but not tumor growth is dependent on Src-mediated vascular permeability. Blood 2005, 105(4):1508-1514.
-
(2005)
Blood
, vol.105
, Issue.4
, pp. 1508-1514
-
-
Criscuoli, M.L.1
Nguyen, M.2
Eliceiri, B.P.3
-
35
-
-
0029068339
-
Hypoxic induction of human vascular endothelial growth factor expression through c-Src activation
-
Mukhopadhyay D., Tsiokas L., Zhou X.M., Foster D., Brugge J.S., Sukhatme V.P. Hypoxic induction of human vascular endothelial growth factor expression through c-Src activation. Nature 1995, 375(6532):577-581.
-
(1995)
Nature
, vol.375
, Issue.6532
, pp. 577-581
-
-
Mukhopadhyay, D.1
Tsiokas, L.2
Zhou, X.M.3
Foster, D.4
Brugge, J.S.5
Sukhatme, V.P.6
-
36
-
-
0032472411
-
The catalytic activity of Src is dispensable for translocation to focal adhesions but controls the turnover of these structures during cell motility
-
Fincham V.J., Frame M.C. The catalytic activity of Src is dispensable for translocation to focal adhesions but controls the turnover of these structures during cell motility. EMBO J 1998, 17(1):81-92.
-
(1998)
EMBO J
, vol.17
, Issue.1
, pp. 81-92
-
-
Fincham, V.J.1
Frame, M.C.2
-
37
-
-
24644471128
-
Src and FAK signalling controls adhesion fate and the epithelial-to-mesenchymal transition
-
October (5)
-
Avizienyte E., Frame M.C. Src and FAK signalling controls adhesion fate and the epithelial-to-mesenchymal transition. Curr Opin Cell Biol 2005, 17(October (5)):542-547.
-
(2005)
Curr Opin Cell Biol
, vol.17
, pp. 542-547
-
-
Avizienyte, E.1
Frame, M.C.2
-
38
-
-
80455132309
-
A phase 2 trial of dasatinib in patients with advanced HER2-positive and/or hormone receptor-positive breast cancer
-
Mayer E., Baurain J., Sparano J., et al. A phase 2 trial of dasatinib in patients with advanced HER2-positive and/or hormone receptor-positive breast cancer. Clin Cancer Res 2011, 17:6897-6904.
-
(2011)
Clin Cancer Res
, vol.17
, pp. 6897-6904
-
-
Mayer, E.1
Baurain, J.2
Sparano, J.3
-
39
-
-
84877088758
-
Dasatinib plus capecitabine for advanced breast cancer: safety and efficacy in phase I study CA180004
-
Somlo G., Atzori F., Strauss L.C., et al. Dasatinib plus capecitabine for advanced breast cancer: safety and efficacy in phase I study CA180004. Clin Cancer Res 2013, 19:1884-1893.
-
(2013)
Clin Cancer Res
, vol.19
, pp. 1884-1893
-
-
Somlo, G.1
Atzori, F.2
Strauss, L.C.3
-
40
-
-
80051832638
-
A phase I study of dasatinib and weekly paclitaxel for metastatic breast cancer
-
Fornier M.N., Morris P.G., Abbruzzi A., et al. A phase I study of dasatinib and weekly paclitaxel for metastatic breast cancer. Ann Oncol 2011, 22:2575-2581.
-
(2011)
Ann Oncol
, vol.22
, pp. 2575-2581
-
-
Fornier, M.N.1
Morris, P.G.2
Abbruzzi, A.3
-
41
-
-
84893732927
-
-
http://clinicaltrials.gov/.
-
-
-
-
42
-
-
84857546448
-
Phase II study of single-agent bosutinib, a Src/Abl tyrosine kinase inhibitor, in patients with locally advanced or metastatic breast cancer pretreated with chemotherapy
-
Campone M., Bondarenko I., Brincat S., et al. Phase II study of single-agent bosutinib, a Src/Abl tyrosine kinase inhibitor, in patients with locally advanced or metastatic breast cancer pretreated with chemotherapy. Ann Oncol 2012, 23:610-617.
-
(2012)
Ann Oncol
, vol.23
, pp. 610-617
-
-
Campone, M.1
Bondarenko, I.2
Brincat, S.3
|