Wif1 hypermethylation as unfavorable prognosis of non-small cell lung cancers with EGFR mutation

Molecules and Cells

Volumn 36, Issue 1, 2013, Pages 69-73

  Lee, Su Man ^a   Park, Jae Yong ^a   Kim, Dong Sun ^a  

^a Kyungpook National University   (South Korea)

Author keywords

Egfr; Hypermethylation; Msp; Nsclc; Prognosis; Wif1

Indexed keywords

BETA CATENIN; EPIDERMAL GROWTH FACTOR RECEPTOR; MESSENGER RNA; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; UNCLASSIFIED DRUG; WNT INHIBITORY FACTOR 1; WNT PROTEIN;

ADENOCARCINOMA; ADENOMA; ADULT; ALLELE; ARTICLE; CANCER PATIENT; CANCER PROGNOSIS; CANCER SURVIVAL; CANCER TISSUE; CONTROLLED STUDY; FEMALE; GENE MUTATION; HUMAN; HUMAN CELL; HUMAN TISSUE; LUNG NON SMALL CELL CANCER; LUNG PARENCHYMA; MALE; META ANALYSIS (TOPIC); MIDDLE AGED; OVERALL SURVIVAL; PROGRESSION FREE SURVIVAL; PROMOTER REGION; PROTEIN METHYLATION; SMOKING; SOMATIC MUTATION;

NICOTIANA TABACUM;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; AGED; CARCINOMA, NON-SMALL-CELL LUNG; DNA METHYLATION; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; KAPLAN-MEIER ESTIMATE; LUNG NEOPLASMS; MALE; MIDDLE AGED; MUTATION; PROGNOSIS; RECEPTOR, EPIDERMAL GROWTH FACTOR; REPRESSOR PROTEINS; RNA, MESSENGER;

EID: 84893694694     PISSN: 10168478     EISSN: 02191032     Source Type: Journal    
DOI: 10.1007/s10059-013-0060-7     Document Type: Article

References (31)

1. Belinsky, S.A., Palmisano, W.A., Gilliland, E.D., Crooks, L.A., Divine, K.K., Winters, S.A., Grimes, M.J., Harms, H.J., Tellez, C.S., Smith, T.M., et al. (2002). Aberrant promoter methylation in bronchial epithelium and sputum from current and former smokers. Cancer Res. 62, 2370-2377.
2. Gazdar, A.F., Shigematsu, H., and Herz, J. (2004). Mutations and addiction to EGFR: the Achilles 'heal' of lung cancers? Trends Mol. Med. 10, 481-486.
3. Guo, M., House, M.G., Hooker, C., Han, Y., Heath, E., Gabrielson, E., Yang, S.C., Baylin, S.B., Herman, J.G., and Brock, M.V. (2004). Promoter hypermethylation of resected bronchial margins: a field defect of changes? Clin. Cancer Res. 10, 5131-5136.
4. Hu, T., and Li, C. (2010). Convergence between Wnt-?-catenin and EGFR signaling in cancer. Mol. Cancer 9, 236-242.
5. Jee, S.H., Samet, J.M., Ohrr, H., Kim, J.H., and Kim, I.S. (2004). Smoking and cancer risk in Korean men and women. Cancer Cases Control 15, 341-348.
6. Jemal, A., Siegel, R., Xu, J., and Ward, E. (2010). Cancer statistics 2010. CA Cancer J. Clin. 60, 277-300.
7. Kerr, K.M., Galler, J.S., Hagen, J.A., Laird, P.W., and Laird-Offringa, I.A. (2007). The role of DNA methylation in the development and progression in lung adenocarcinoma. Disease Marker 23, 5-30.
8. Kim, D.S., Cha, S.I., Lee, J.H., Lee, Y.M., Choi, J.E., Kim, M.J., Lim, J.S., Lee, E.B., Kim, C.H., Park, T.I., et al. (2007). Aberrant DNA methylation profiles of non-small cell lung cancers in a Korean population. Lung Cancer 58, 1-6.
9. Konigshoff, M., and Eickelberg, O. (2010). WNT signaling in lung disease. Am. J. Respir. Cell. Mol. Biol. 42, 21-31.
10. Lee, S.M., Park, J.Y., and Kim, D.S. (2012). Methylation of TMEFF2 gene in tissue and serum DNA from patients with non-small cell lung cancer. Mol. Cells 34, 171-176.
11. Lemjabbar-Alaoui, H., Dasari, V., Sidhu, S., Mengistab, A., Finkbeiner, W., Gallup, M., and Basbaum, C. (2006). Wnt and hedgehog are critical mediators of cigarette smoke-induced lung cancer. PLoS One 1, 1-11.
12. Licchesi, J.D.F., Westra, W.H., Hooker, C.M., Machida, E.O., Baylin, S.B., and Herman, J.G. (2008). Epignetic alteration of Wnt pathway antagonists in progressive glandular neoplasia of the lung. Carcinogenesis 29, 895-904.
13. Liu, F., Killian, J.K., Yang, M., Walker, R.L., Hong, J.A., Zhang, M., Davis, S., Zhang, Y., Hussain, M., Xi, S., et al. (2010). Epigenomic alterations and gene expression profiles in respiratory epithelia exposed to cigarette smoke condensate. Oncogene 29, 3650-3664.
14. Mazieres, J., He, B., You, L., Xu, Z., Lee, A.Y., Mikami, I., Reguart, N., Rosell, R., McCormick, F., and Jablons, D.M. (2004). Wnt inhibitory factor is silenced by promoter hypermethylation in human lung cancer. Cancer Res. 64, 717-720.
15. Mazieres, J., He, B., You, L., Xu, Z., and Jablons, D.M. (2005). Wnt signaling in lung cancer. Cancer Lett. 222, 1-10.
16. Minna, J.D., Roth, J.A., and Gazdar, A.F. (2002). Focus on lung cancer. Cancer Cell 1, 49-52.
17. Na, Y.K., Lee, S.M., Hong, H.S., Kim, J.B., Park, J.Y., and Kim, D.S. (2010). Hypermethylation of growth arrest DNA-damage inducible gene 45 in non-small cell lung cancer and its relationship with clinicopathologic features. Mol. Cells 30, 89-92.
18. Na, Y.K., Lee, S.M., Kim, D.S., and Park, J.Y. (2012). Promoter methylation of Wnt antagonist DKK1 gene and prognostic value in Korean patients with non-small cell lung cancers. Cancer Biomarkers 12, 73-79.
19. Nakamura, H., Kawasaki, N., Taguchi, M., and Kabasawa, K. (2006). Survival impact of epidermal growth factor receptor overexpression in patients with non-small cell lung cancer: a meta-Analysis. Thorax 61, 140-145.
20. Ohtsuka, K., Ohnishi, H., Furuyashiki, G., Nogami, H., Koshiishi, Y., Ooide, A., Matsushima, S., Watanabe, T., and Goya, T. (2006). Clinico-pathological and biological significance of tyrosine kinase domain gene mutations and overexpression of epidermal growth factor receptor for lung adenocarcinoma. J. Thorac. Oncol. 8, 787-795.
21. Paul, S., and Dey, A. (2008). Wnt signaling and cancer development: therapeutic implication. Neoplasma 55, 165-176.
22. Rubin, J.S., Barshishat-Kupper, M., Feroze-Merzoug, F., and Xi, Z.F. (2006). Secreted WNT antagonists as tumor suppressors: pro and con. Front. Biosci. 11, 2093-105.
23. Sharm, S.V., Bell, D.W., Settleman, J., and Haber, D.A. (2007). Epidermal growth factor receptor mutations in lung cancer. Nat. Rev. Cancer 7, 169-181.
24. Tang, M., Torres-Lanzas, J., Lopez-Rios, F., Esteller, M., and Sanchez-Cespedes, M. (2006). Wnt signaling promoter hyperemthylation distinguishes lung primary adenocarcinomas from colorectal metastasis to the lung. Int. J. Cancer 119, 2603-2606.
25. Toyooka, S., Toyook, K.O., Maruyama, R., Virmani, A.K., Girard, L., Miyajima, K., Harada, K., Ariyoshi, Y., Takahashi, T., Sugio, K., et al. (2001). DNA methylation profiles of lung tumors. Mol. Cancer Ther. 1, 61-67.
26. Toyooka, S., Maruyama, R., and Toyooka, K.O. (2003). Smoke exposure, histologic type and geography-related differences in the methylation profiles of non-small cell lung cancer. Int. J. Cancer 103, 153-160.
27. Van Scoyk, M., Randall, J., Sergew, A., Williams, L.M., Tennis, M., and Winn, R.A. (2008). Wnt signaling pathway and lung disease. Transl. Res. 151, 175-180.
28. Wang, R., Ahmed, J., Wang, G., Hassan, I., Strulovici-Barel, Y., Hackett, N.R., and Crystal, R.G. (2011). Down-regulation of the canonical Wnt ?-catenin pathway in the airway epithelium of healthy smokers and smokers with COPD. PLoS One 6, e14793.
29. Ying, Y., and Tao, Q. (2009). Epigenetic disruption of the WNT/?-catenin signaling pathway in human cancers. Epigenetics 4, 307-312.
30. Yoshino, M., Suzuki, M., Tian, L., Moriya, Y., Hoshino, H., Okamoto, T., Yoshida, S., Shibuya, K., and Yoshino, I. (2009). Promoter hypermethylation of the p16 and Wif-1 genes as an independent prognostic marker in stage IA non-small cell lung cancers. Int. J. Oncol. 35, 1201-1209.
31. Zhu, J., Wang, Y., Duan, J., Bai, H., Wang, Z., Wei, L., Zhao, J., Zhou, M., Wang, S., Yang, L., et al. (2012). DNA methylation status of Wnt antagonist SFRP5 can predict the response to the EGFR-tyrosine kinase inhibitor therapy in non-small cell lung cancer. J. Exp. Clin. Cancer Res. 31, 80-88.