Short-term splenic impact of single-strand DNA functionalized multi-walled carbon nanotubes intraperitoneally injected in rats

Journal of Applied Toxicology

Volumn 34, Issue 4, 2014, Pages 332-344

  Clichici, Simona ^a   Biris, Alexandru Radu ^b   Catoi, Cornel ^c   Filip, Adriana ^a   Tabaran, Flaviu ^c  

^a IULIU HATIEGANU UNIVERSITY OF MEDICINE AND PHARMACY   (Romania)

^b NATIONAL INSTITUTE FOR RESEARCH AND DEVELOPMENT OF ISOTOPIC AND MOLECULAR TECHNOLOGIES   (Romania)

^c UNIVERSITY OF AGRICULTURAL SCIENCES AND VETERINARY MEDICINE   (Romania)

Author keywords

Apoptosis; Cytotoxicity; Lymphoid hyperplasia; Multi walled carbon nanotubes; Oxidative stress

Indexed keywords

CARBONYL DERIVATIVE; CASPASE 3; CYCLINE; GLUTATHIONE; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERLEUKIN 1BETA; MALONALDEHYDE; MULTI WALLED NANOTUBE; NITRIC OXIDE; SINGLE STRANDED DNA;

ADULT; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BODY WEIGHT; CELL PROLIFERATION; CONFOCAL LASER MICROSCOPY; CONFOCAL MICROSCOPY; CONTROLLED STUDY; DISPERSION; ELECTRON MICROSCOPY; HISTOPATHOLOGY; IMMUNOHISTOCHEMISTRY; LYMPH FOLLICLE; LYMPHOID HYPERPLASIA; MALE; MITOSIS; MORPHOMETRICS; NITROSATIVE STRESS; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAMAN SPECTROMETRY; RAT; SPLEEN; SPLEEN TOXICITY; SURFACE PROPERTY; TOXICITY; TRANSMISSION ELECTRON MICROSCOPY;

RATTUS;

APOPTOSIS; CYTOTOXICITY; LYMPHOID HYPERPLASIA; MULTI-WALLED CARBON NANOTUBES; OXIDATIVE STRESS;

ANIMALS; CASPASE 3; DNA, SINGLE-STRANDED; INJECTIONS, INTRAPERITONEAL; INTERLEUKIN-1BETA; MALE; MICROSCOPY, CONFOCAL; MICROSCOPY, ELECTRON, TRANSMISSION; NANOTUBES, CARBON; NITRIC OXIDE; NITRIC OXIDE SYNTHASE TYPE II; OXIDATIVE STRESS; PARTICLE SIZE; PROLIFERATING CELL NUCLEAR ANTIGEN; RATS; RATS, WISTAR; SPECTRUM ANALYSIS, RAMAN; SPLEEN; TIME FACTORS; TISSUE DISTRIBUTION; TOXICITY TESTS;

EID: 84893689728     PISSN: 0260437X     EISSN: 10991263     Source Type: Journal    
DOI: 10.1002/jat.2883     Document Type: Article

References (45)

1. Berlett BS, Stadtman ER. 1997. Protein oxidation in aging, disease and oxidative stress. J. Biol. Chem. 272: 20313-20316.
2. Biris AR, Biris AS, Lupu D, Trigwell S, Dervishi E, Rahman Z, Marginean P. 2006. Catalyst excitation by radio frequency for improved carbon nanotubes synthesis. Chem. Phys. Lett. 429: 204-208.
3. Biris AS, Schmitt TC, Little RB, Li Z, Biris AR, Lupu D, Dervishi E, Trigwell S, Miller DW, Rahman Z. 2007. Influence of the RF excitation of the catalyst system on the morphology of multi-wall carbon nanotubes. J. Phys. Chem. C 111: 17970-17975.
4. Cesta MF. 2006. Normal structure, function, and histology of the spleen. Toxicol. Pathol. 34: 455-465.
5. Clichici S, Biris AR, Tabaran F, Filip A. 2012. Transient oxidative stress and inflammation after intraperitoneal administration of multiwalled carbon nanotubes functionalized with single strand DNA in rats. Toxicol. Appl. Pharmacol. 259: 281-292.
6. Clichici S, Mocan T, Filip A, Biris A, Simon S, Daicoviciu D, Decea N, Parvu A, Moldovan R, Muresan A. 2011. Blood oxidative stress generation after intraperitoneal administration of functionalized single-walled carbon nanotubes in rats. Acta Physiol. Hun. 98: 231-241.
7. Conti M, Morand PC, Levillain P, Lemonnier A. 1991. Improved fluorimetric determination of malondialdehyde. Clin. Chem. 3: 1273-1275.
8. Deng X, Wu F, Liu Z, Luo M, Li L, Ni Q, Jiao Z, Wu M, Liu Y. 2009. The splenic toxicity of water soluble multi-walled carbon nanotubes in mice. Carbon 47: 1421-1428.
9. Elmore SA. 2006. Enhanced histopathology of the spleen. Toxicol. Pathol. 34: 648-655.
10. Fujigaya T, Nakashima N. 2008. Methodology for homogeneous dispersion of single-walled carbon nanotubes by physical modification. Polymer. J. 40: 577-589.
11. Germolec DR, Kashon M, Nyska A, Kuper CF, Portier C, Kommineni C, Johnson KA, Luster MI. 2004. The accuracy of extended histopathology to detect immunotoxic chemicals. Toxicol. Sci. 82: 504-514.
12. Haley P, Perry R, Ennulat D, Frame S, Johnson C, Lapointe JM, Nyska A, Snyder PW, Walker D, Walter G. 2005. STP Position Paper: Best Practice Guideline for the Routine Pathology Evaluation of the Immune System. Toxicol. Pathol. 33: 404-407.
13. Han SG, Andrews R, Gairola CG. 2010. Acute pulmonary response of mice to multi-wall carbon nanotubes. Inhal. Toxicol. 22: 340-347.
14. Hu ML. 1994. Measurement of protein thiol groups and glutathione in plasma. Methods Enzymol. 233: 380-384.
15. Jana M, Anderson JA, Saha RN, Liu X, Pahan K. 2005. Regulation of inducible nitric oxide synthase in proinflammatory cytokine-stimulated human primary astrocytes. Free Rad. BioMed. 38: 655-664.
16. Kawaguchi M, Ohno J, Irie A, Fukushima T, Yamazaki J, Nakashima N. 2011. Dispersion stability and exothermic properties od DNA-functionalized single-walled carbon nanotubes. Int. J. Nanomed. 6: 729-736.
17. Kuper CF, Harleman JH, Richter-Reichelm HB, Vos JG. 2000. Histopathologic approaches to detect changes indicative of immunotoxicity. Toxicol. Pathol. 28: 454-466.
18. Lacerda L, Ali-Boucetta H, Herrero MA, Pastorin G, Bianco A, Prato M, Kostarelos K. 2008. Tissue histology and physiology following intravenous administration of different types of functionalized multiwalled carbon nanotubes. Nanomedicine 3: 149-161.
19. Liang G, Yin L, Zhang J, Liu R, Zhang T, Ye B, Pu Y. 2010a. Effects of subchronic exposure to multi-walled carbon nanotubes on mice. J. Toxicol. Environ. Health A 73: 463-470.
20. Liang G, Zhang T, Liu R, Ye B, Yin L, Pu Y. 2010b. Preparation and biodistribution of tyrosine modified multiwall carbon nanotubes. J. Nanosci. Nanotechnol. 10: 8508-8515.
21. Liu X, Guo L, Morris D, Kane AB, Hurt RH. 2008. Targeted removal of bioavailable metal as a detoxification strategy for carbon nanotubes. Carbon 46: 489-500.
22. Liu Z, Tabakman S, Welsher K, Dai H. 2009. Carbon nanotubes in biology and medicine: In vitro and in vivo detection, imaging and drug delivery. Nano Res. 2: 85-120.
23. Meng J, Yang M, Jia F, Xu Z, Kong H, Xu H. 2011. Immune responses of BALB/c mice to subcutaneously injected multi-walled carbon nanotubes. Nanotoxicology 5: 583-591.
24. Mitchell LA, Gao J, Wal RV, Gigliotti A, Burchiel SW, McDonald JD. 2007. Pulmonary and systemic immune response to inhaled multiwalled carbon nanotubes. Toxicol. Sci. 100: 203-214.
25. Moghimi SM, Hunter AC, Murray JC. 2001. Long-circulating and target-specific nanoparticles: theory to practice. Pharmacol. Rev. 53: 283-318.
26. Muller J, Huaux F, Moreau N, Misson P, Heilier JF, Delos M, Arras M, Fonseca A, Nagy JB, Lison D. 2005. Respiratory toxicity of multi-wall carbon nanotubes. Toxicol. Appl. Pharmacol. 207: 221-231.
27. Muresan A, Clichici S, Mocan T, Filip A, Biris AR, Simon S, Daicoviciu D, Moldovan R, Mocan LC, Biris AS. 2010. Effects of different concentrations of carbon nanotubes upon the pattern of oxidative stress generation after intraperitoneal administration. Acta Physiol. 198 (Suppl. 667): 68.
28. Murray AR, Kisin E, Leonard SS, Young SH, Kommineni C, Kagan VE, Castranova V, Shvedova AA. 2009. Oxidative stress and inflammatory response in dermal toxicity of single-walled carbon nanotubes. Toxicology 257: 161-171.
29. Murray JA, Slater DN, Parsons MA, Fox M, Smith S, Platts MM. 1984. Splenic siderosis and parenteral iron dextran in maintenance haemodialysis patients. J. Clin. Pathol. 37: 59-64.
30. Nakashima N, Okuzono S, Murakami H, Nakai T, Yoshizawa K. 2003. DNA dissolves single-walled carbon nanotubes in water. Chem. Lett. 32: 456-457.
31. Noble JE, Bailey MJA. 2009. Quantitation of protein. Methods Enzymol. 463: 72-95.
32. Park YH, Jeong SH, Lee EY, Lee SH, Choi BH, Kim MK, Son SW. 2011. Assessment of Dermal Irritation Potential of MWCNT. Toxicol. Environ. Health Sci. 2: 115-118.
33. Patlolla A, Knighten B, Tchounwou P. 2010. Multi-walled carbon nanotubes induce cytotoxicity, genotoxicity and apoptosis in normal human dermal fibroblast cells. Ethn. Dis. 20 (1 Suppl 1): S1-65-72.
34. Patlolla A, McGinnis B, Tchounwou P. 2011. Biochemical and histopatological evaluation of functionalized single-walled carbon nanotubes in Swiss-Webster mice. J. Appl. Toxicol. 31: 75-83.
35. Prophet EB, Mills B, Arrington JB, Sobin LH. 1992. Laboratory Methods in Histotechnology. Armed Forces Institute of Pathology-American Registry of Pathology: Washington, DC; 53-58, 128-130, 134-136, 156-158, 170, 177-178.
36. Rahman I, MacNee W. 2000. Oxidative stress and regulation of glutathione in lung inflammation. Eur. Respir. J. 16: 534-554.
37. Reznick AZ, Packer L. 1994. Oxidative damage to proteins: spectrophotometric method for carbonyl assay. Methods Enzymol. 233: 357-363.
38. Riviere JE. 2009. Pharmacokinetics of nanomaterials: an overview of carbon nanotubes, fullerenes and quantum dots. Nanomed. Nanobiotechnol. 191: 26-34.
39. Salzmann CG, Chu B, Tobias G, Llewellyn SA, Green M. 2007. Quantitative assessment of carbon nanotubes dispersions by Raman spectroscopy. Carbon 45: 907-912.
40. Sharma CS, Sarkar S, Periyakaruppan A, Barr J, Wise K, Thomas R, Wilson BL, Ramesn GT. 2007. Single-walled carbon nanotubes induces oxidative stress in rat lung epithelial cells. J. Nanosci. Nanotechnol. 7: 2466-2472.
41. Titheradge MA. 1998. The enzymatic measurement of nitrate and nitrite. In Methods in Molecular Biology, vol 100. Nitric Oxide Protocols, Titheradge MA (ed.). Humana Press: Totowa, NJ; 83-91.
42. Valko M, Rhodes CJ, Moncol J, Izakovic M, Mazur M. 2006. Free radicals, metals, and antioxidants in oxidative stress-induced cancer. Chem. Biol. Interact. 160: 1-40.
43. Ward M, Reznik-Schüller H. 1980. Morphological and Histochemical Characteristics of Pigments in Aging F344 Rats. Vet. Pathol. 17: 678-685.
44. Yamashita K, Yoshioka Y, Higashisaka K, Morishita Y, Yoshida T, Fujimura M, Kayamuro H, Nabeshi H, Yamashita T, Nagano K. 2010. Carbon nanotubes elicit DNA damage and inflammatory response relative to their size and shape. Inflammation 33: 276-280.
45. Ye S, Wang Y, Jiao F, Zhang H, Lin C, Wu Y, Zhang Q. 2011. The Role of NADPH Oxidase in Multi-Walled Carbon Nanotubes-Induced Oxidative Stress and Cytotoxicity in Human Macrophages. J. Nanosci. Nanotechnol. 11: 3773-3781.