Evolution of computed tomography angiography spot sign is consistent with a site of active hemorrhage in acute intracerebral hemorrhage

Stroke

Volumn 45, Issue 1, 2014, Pages 277-280

  Dowlatshahi, Dar ^a   Wasserman, Jason K ^a   Momoli, Franco ^a   Petrcich, William ^a   Stotts, Grant ^a   Hogan, Matthew ^a   Sharma, Mukul ^b   Aviv, Richard I ^c   Demchuk, Andrew M ^d   Chakraborty, Santanu ^a  

^a OTTAWA HOSPITAL RESEARCH INSTITUTE   (Canada)

^b MCMASTER UNIVERSITY   (Canada)

^c UNIVERSITY OF TORONTO   (Canada)

^d UNIVERSITY OF CALGARY   (Canada)

Author keywords

Cerebral hemorrhage; Computerized tomography; Contrast agent; Hematoma

Indexed keywords

EID: 84893667638     PISSN: 00392499     EISSN: 15244628     Source Type: Journal    
DOI: 10.1161/Strokeaha.113.003387     Document Type: Article

References (15)

1. Davis SM, Broderick J, Hennerici M, Brun NC, Diringer MN, Mayer SA, et al; Recombinant Activated Factor VII Intracerebral Hemorrhage Trial Investigators. Hematoma growth is a determinant of mortality and poor outcome after intracerebral hemorrhage. Neurology. 2006;66:1175-1181.
2. Wada R, Aviv RI, Fox AJ, Sahlas DJ, Gladstone DJ, Tomlinson G, et al. CT angiography "spot sign" predicts hematoma expansion in acute intracerebral hemorrhage. Stroke. 2007;38:1257-1262.
3. Goldstein JN, Fazen LE, Snider R, Schwab K, Greenberg SM, Smith EE, et al. Contrast extravasation on CT angiography predicts hematoma expansion in intracerebral hemorrhage. Neurology. 2007;68:889-894.
4. Kim J, Smith A, Hemphill JC III, Smith WS, Lu Y, Dillon WP, et al. Contrast extravasation on CT predicts mortality in primary intracerebral hemorrhage. AJNR Am J Neuroradiol. 2008;29:520-525.
5. Li N, Wang Y, Wang W, Ma L, Xue J, Weissenborn K, et al. Contrast extravasation on computed tomography angiography predicts clinical outcome in primary intracerebral hemorrhage: a prospective study of 139 cases. Stroke. 2011;42:3441-3446.
6. Demchuk AM, Dowlatshahi D, Rodriguez-Luna D, Molina CA, Blas YS, Dzialowski I, et al; PREDICT/Sunnybrook ICH CTA Study Group. Prediction of haematoma growth and outcome in patients with intracerebral haemorrhage using the CT-angiography spot sign (PREDICT): a prospective observational study. Lancet Neurol. 2012;11:307-314.
7. Fisher CM. Cerebral miliary aneurysms in hypertension. Am J Pathol. 1972;66:313-330.
8. Chakraborty, S, Blacquiere D, Lum C, and Stotts, G. Dynamic nature of the CTA "spot sign". British J Radiology. 2010;83:e216-e219.
9. Thompson AL, Kosior JC, Gladstone DJ, Hopyan JJ, Symons SP, Romero F, et al; PREDICTS/Sunnybrook ICH CTA Study Group. Defining the CT angiography 'spot sign' in primary intracerebral hemorrhage. Can J Neurol Sci. 2009;36:456-461.
10. Dowlatshahi D, Kosior JC, Idris S, Eesa M, Dickhoff P, Joshi M, et al; PREDICT/Sunnybrook ICH-CTA Study Group. Planimetric hematoma measurement in patients with intraventricular hemorrhage: is total volume a preferred target for reliable analysis? Stroke. 2012;43:1961-1963.
11. d'Esterre CD, Chia TL, Jairath A, Lee TY, Symons SP, Aviv RI. Early rate of contrast extravasation in patients with intracerebral hemorrhage. AJNR Am J Neuroradiol. 2011;32:1879-1884.
12. Sun SJ, Gao PY, Sui BB, Hou XY, Lin Y, Xue J, et al. "Dynamic spot sign" on CT perfusion source images predicts haematoma expansion in acute intracerebral haemorrhage. Eur Radiol. 2013;23:1846-1854.
13. Huynh TJ, Demchuk AM, Dowlatshahi D, Gladstone DJ, Krischek O, Kiss A, et al; PREDICT/Sunnybrook ICH CTA Study Group. Spot sign number is the most important spot sign characteristic for predicting hematoma expansion using first-pass computed tomography angiography: analysis from the PREDICT study. Stroke. 2013;44:972-977.
14. Delgado Almandoz JE, Yoo AJ, Stone MJ, Schaefer PW, Goldstein JN, Rosand J, et al. Systematic characterization of the computed tomography angiography spot sign in primary intracerebral hemorrhage identifies patients at highest risk for hematoma expansion: the spot sign score. Stroke. 2009;40:2994-3000.
15. Koculym A, Huynh TJ, Jakubovic R, Zhang L, Aviv RI. CT perfusion spot sign improves sensitivity for prediction of outcome compared with CTA and postcontrast CT. AJNR Am J Neuroradiol. 2013;34:965-70, S1.