"dynamic spot sign" on CT perfusion source images predicts haematoma expansion in acute intracerebral haemorrhage

European Radiology

Volumn 23, Issue 7, 2013, Pages 1846-1854

  Sun, Sheng Jun ^a   Gao, Pei Yi ^a   Sui, Bin Bin ^a   Hou, Xin Yi ^a   Lin, Yan ^a   Xue, Jing ^a   Zhai, Ren You ^b  

^a CAPITAL MEDICAL UNIVERSITY   (China)

^b CAPITAL MEDICAL UNIVERSITY   (China)

Author keywords

Computed tomography; Intracerebral haemorrhage; Perfusion; Prognosis; Source images

Indexed keywords

ACUTE DISEASE; ADULT; AGED; ARTICLE; BRAIN HEMATOMA; BRAIN HEMORRHAGE; BRAIN PERFUSION; BRAIN RADIOGRAPHY; COMPUTED TOMOGRAPHIC ANGIOGRAPHY; COMPUTER ASSISTED TOMOGRAPHY; FEMALE; FOLLOW UP; HUMAN; MAJOR CLINICAL STUDY; MALE; PATIENT ASSESSMENT; PREDICTION; PREDICTIVE VALUE; PRIORITY JOURNAL; PROSPECTIVE STUDY; SENSITIVITY AND SPECIFICITY; SYMPTOM;

ADULT; AGED; AGED, 80 AND OVER; CEREBRAL ANGIOGRAPHY; CEREBRAL HEMORRHAGE; FEMALE; HEMATOMA; HEMORRHAGE; HUMANS; IMAGE PROCESSING, COMPUTER-ASSISTED; MALE; MIDDLE AGED; OBSERVER VARIATION; PERFUSION; PREDICTIVE VALUE OF TESTS; PROSPECTIVE STUDIES; REGRESSION ANALYSIS; SENSITIVITY AND SPECIFICITY; TOMOGRAPHY, X-RAY COMPUTED;

EID: 84879015635     PISSN: 09387994     EISSN: 14321084     Source Type: Journal    
DOI: 10.1007/s00330-013-2803-4     Document Type: Article

References (33)

1. Broderick JP, Adams HP Jr, Barsan W et al (1999) Guidelines for the management of spontaneous intracerebral hemorrhage: a statement for healthcare professionals from a special writing group of the Stroke Council, American Heart Association. Stroke 30:905-915
2. Broderick JP, Brott T, Tomsick T et al (1992) The risk of subarachnoid and intracerebral hemorrhages in blacks as compared with whites. N Engl J Med 326:733-736
3. Broderick JP, Brott TG, Duldner JE et al (1993) Volume of intracerebral hemorrhage: a powerful and easy-to-use predictor of 30-day mortality. Stroke 24:987-993
4. Hemphill JC 3rd, Bonovich DC, Besmertis L, Manley GT, Johnston SC (2001) The ICH score: a simple, reliable grading scale for intracerebral hemorrhage. Stroke 32:891-897
5. Leira R, Davalos A, Silva Y et al (2004) Stroke Project, Cerebrovascular Diseases Group of the Spanish Neurological Society. Early neurologic deterioration in intracerebral hemorrhage: predictors and associated factors. Neurology 10:461-467
6. Davis SM, Broderick J, Hennerici M et al (2006) Recombinant activated factor VII intracerebral hemorrhage trial investigators. Hematoma growth is a determinant of mortality and poor outcome after intracerebral hemorrhage. Neurology 66:1175-1181
7. NINDS ICH Workshop Participants (2005) Priorities for clinical research in intracerebral hemorrhage: report from a National Institute of Neurological Disorders and Stroke workshop. Stroke 36:23-41.
8. Mayer SA, Rincon F (2006) Ultra-early hemostatic therapy for acute intracerebral hemorrhage. Semin Hematol 43:S70-S76
9. Mayer SA, Brun NC, Begtrup K et al (2005) Recombinant activated factor VII intracerebral hemorrhage trial investigators. Recombinant activated factor VII for acute intracerebral hemorrhage. N Engl J Med 352:777-785
10. Flibotte JJ, Hagan N, O'Donnell J et al (2004) Warfarin, hematoma expansion, and outcome of intracerebral hemorrhage. Neurology 63:1059-1064
11. Flaherty ML, Woo D, Haverbusch M et al (2005) Potential applicability of recombinant factor VIIa for intracerebral hemorrhage. Stroke 36:2660-2664
12. Yasui T, Kishi H, Komiyama M et al (1996) Very poor prognosis in cases with extravasation of the contrast medium during angiography. Surg Neurol 45:560-565
13. Murai Y, Ikeda Y, Teramoto A et al (1998) Magnetic resonance imaging documented extravasation as an indicator of acute hypertensive intracerebral hemorrhage. J Neurosurg 88:650-655
14. Walker MT, Wattamwar A, Mellman D et al (2005) Active hemorrhage into a postresection cavity detected by neuro-CT angiography. AJNR Am J Neuroradiol 26:1163-1165
15. Becker KJ, Baxter AB, Bybee HM et al (1999) Extravasation of radiographic contrast is an independent predictor of death in primary intracerebral. Stroke 30:2025-2032
16. Brouwers HB, Falcone GJ, McNamara KA et al (2012) CTA spot sign predicts hematoma expansion in patients with delayed presentation after intracerebral hemorrhage. Neurocrit Care 17:421-428
17. Romero JM, Heit JJ, Delgado Almandoz JE et al (2012) Spot sign score predicts rapid bleeding in spontaneous intracerebral hemorrhage. Emerg Radiol 19:195-202
18. Wada R, Aviv RI, Fox AJ et al (2007) CT angiography "spot sign" predicts hematoma expansion in acute intracerebral hemorrhage. Stroke 38:1257-1262
19. Demchuk AM, Dowlatshahi D, Rodriguez-Luna D et al (2012) Prediction of haematoma growth and outcome in patients with intracerebral haemorrhage using the CT-angiography spot sign (PREDICT): a prospective observational study. Lancet Neurol 11:307-314
20. d'Esterre CD, Chia TL, Jairath A et al (2011) Early rate of contrast extravasation in patients with intracerebral hemorrhage. AJNR Am J Neuroradiol 32:1879-1884
21. Kothari RU, Brott T, Broderick JP et al (1996) The ABCs of measuring intracerebral hemorrhage volumes. Stroke 27:1304-1305
22. Ohwaki K, Yano E, Nagashima H et al (2004) Blood pressure management in acute intracerebral hemorrhage: relationship between elevated blood pressure and hematoma enlargement. Stroke 35:1364-1367
23. Toyoda K, Okada Y, Minematsu K et al (2005) Antiplatelet therapy contributes to acute deterioration of intracerebral hemorrhage. Neurology 65:1000-1004
24. Fisher CM (1971) Pathological observations in hypertensive cerebral hemorrhage. J Neuropathol Exp Neurol 30:536-550
25. Huynh TJ, Keith J, Aviv RI (2012) Histopathological characteristics of the "spot sign" in spontaneous intracerebral hemorrhage. Arch Neurol 24:1-2
26. Ederies A, Demchuk A, Chia T et al (2009) Postcontrast CT extravasation is associated with hematoma expansion in CTA spot negative patients. Stroke 40:1672-1676
27. Almandoz JE, Yoo AJ, Stone MJ et al (2009) Systematic characterization of the computed tomography angiography spot sign in primary intracerebral hemorrhage identifies patients at highest risk for hematoma expansion: the spot sign score. Stroke 40:2994-3000
28. Kim J, Smith A, Hemphill JC et al (2008) Contrast extravasation on CT predicts mortality in primary intracerebral hemorrhage. AJNR Am J Neuroradiol 29:520-525
29. Hoh BL, Cheung AC, Rabinov JD et al (2004) Results of a prospective protocol of computed tomographic angiography in place of catheter angiography as the only diagnostic and pretreatment planning study for cerebral aneurysms by a combined neurovascular team. Neurosurgery 54:1329-1340
30. Sanelli PC, Mifsud MJ, Stieg PE (2004) Role of CT angiography in guiding management decisions of newly diagnosed and residual arteriovenous malformations. AJR Am J Roentgenol 183:1123-1126
31. Fainardi E, Borrelli M, Saletti A et al (2008) CT perfusion mapping of hemodynamic disturbances associated to acute spontaneous intracerebral hemorrhage. Neuroradiology 50:729-740
32. Mayer SA, Rincon F (2005) Treatment of intracerebral haemorrhage. Lancet Neurol 4:662-672
33. Xi G, Keep RF, Hoff JT (2006) Mechanisms of brain injury after intracerebral haemorrhage. Lancet Neuro 15:53-63