Prediction of haematoma growth and outcome in patients with intracerebral haemorrhage using the CT-angiography spot sign (PREDICT): A prospective observational study

The Lancet Neurology

Volumn 11, Issue 4, 2012, Pages 307-314

  Demchuk, Andrew M ^a   Dowlatshahi, Dar ^b   Rodriguez Luna, David ^c   Molina, Carlos A ^c   Blas, Yolanda Silva ^d   Dzialowski, Imanuel ^e   Kobayashi, Adam ^f   Boulanger, Jean Martin ^g   Lum, Cheemun ^b   Gubitz, Gord ^h   Padma, Vasantha ⁱ   Roy, Jayanta ^j   Kase, Carlos S ^k   Kosior, Jayme ^a   Bhatia, Rohit ⁱ   Tymchuk, Sarah ^a   Subramaniam, Suresh ^a   Gladstone, David J ^l   Hill, Michael D ^m   Aviv, Richard I ^l  

^a UNIVERSITY OF CALGARY   (Canada)

^b OTTAWA HOSPITAL RESEARCH INSTITUTE   (Canada)

^c HOSPITAL UNIVERSITARI VALL D HEBRON   (Spain)

^d GIRONA BIOMEDICAL RESEARCH INSTITUTE IDIBGI   (Spain)

^e DRESDEN UNIVERSITY OF TECHNOLOGY   (Germany)

^f INSTITUTE OF PSYCHIATRY AND NEUROLOGY   (Poland)

^g HÔPITAL CHARLES LEMOYNE   (Canada)

^h DALHOUSIE UNIVERSITY   (Canada)

ⁱ ALL INDIA INSTITUTE OF MEDICAL SCIENCES   (India)

^j AMRI HOSPITALS   (India)

^k BOSTON MEDICAL CENTER   (United States)

^l SUNNYBROOK RESEARCH INSTITUTE   (Canada)

^m UNIVERSITY OF CALGARY   (Canada)

more..

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; ARTICLE; BRAIN HEMORRHAGE; COMPUTED TOMOGRAPHIC ANGIOGRAPHY; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DEATH; DIAGNOSTIC ACCURACY; DIAGNOSTIC TEST ACCURACY STUDY; DIAGNOSTIC VALUE; FEMALE; FOLLOW UP; HEMATOMA; HUMAN; MAJOR CLINICAL STUDY; MALE; MORTALITY; MULTICENTER STUDY; OBSERVATIONAL STUDY; OUTCOME ASSESSMENT; PREDICTIVE VALUE; PRIORITY JOURNAL; PROSPECTIVE STUDY; RANKIN SCALE; SENSITIVITY AND SPECIFICITY; SINGLE BLIND PROCEDURE; TUMOR GROWTH; TUMOR VOLUME;

ADULT; AGED; AGED, 80 AND OVER; CEREBRAL ANGIOGRAPHY; CEREBRAL ARTERIES; CEREBRAL HEMORRHAGE; FEMALE; HEMATOMA; HUMANS; MALE; MIDDLE AGED; OBSERVATION; PREDICTIVE VALUE OF TESTS; PROGNOSIS; PROSPECTIVE STUDIES; TOMOGRAPHY, X-RAY COMPUTED; YOUNG ADULT;

EID: 84858618556     PISSN: 14744422     EISSN: 14744465     Source Type: Journal    
DOI: 10.1016/S1474-4422(12)70038-8     Document Type: Article

References (30)

1. Broderick JP, Brott T, Tomsick T, Miller R, Huster G Intracerebral hemorrhage more than twice as common as subarachnoid hemorrhage. J Neurosurg 1993, 78:188-191.
2. Hemphill JC, Bonovich DC, Besmertis L, Manley GT, Johnston SC The ICH score: a simple, reliable grading scale for intracerebral hemorrhage. Stroke 2001, 32:891-897.
3. Leira R, Davalos A, Silva Y, et al. Early neurologic deterioration in intracerebral hemorrhage: predictors and associated factors. Neurology 2004, 63:461-467.
4. Brott T, Broderick J, Kothari R, et al. Early hemorrhage growth in patients with intracerebral hemorrhage. Stroke 1997, 28:1-5.
5. Davis SM, Broderick J, Hennerici M, et al. Hematoma growth is a determinant of mortality and poor outcome after intracerebral hemorrhage. Neurology 2006, 66:1175-1181.
6. Mayer SA, Brun NC, Begtrup K, et al. Recombinant activated factor VII for acute intracerebral hemorrhage. N Engl J Med 2005, 352:777-785.
7. Mayer SA, Brun NC, Begtrup K, et al. Efficacy and safety of recombinant activated factor VII for acute intracerebral hemorrhage. N Engl J Med 2008, 358:2127-2137.
8. Mayer SA, Davis SM, Skolnick BE, et al. Can a subset of intracerebral hemorrhage patients benefit from hemostatic therapy with recombinant activated factor VII?. Stroke 2009, 40:833-840.
9. Wada R, Aviv RI, Fox AJ, et al. CT angiography " spot sign" predicts hematoma expansion in acute intracerebral hemorrhage. Stroke 2007, 38:1257-1262.
10. Goldstein JN, Fazen LE, Snider R, et al. Contrast extravasation on CT angiography predicts hematoma expansion in intracerebral hemorrhage. Neurology 2007, 68:889-894.
11. Kim J, Smith A, Hemphill JC, et al. Contrast extravasation on CT predicts mortality in primary intracerebral hemorrhage. AJNR Am J Neuroradiol 2008, 29:520-525.
12. Li N, Wang Y, Wang W, et al. Contrast extravasation on computed tomography angiography predicts clinical outcome in primary intracerebral hemorrhage: a prospective study of 139 cases. Stroke 2011, 42:3441-3446.
13. Wang YH, Fan JY, Luo GD, et al. Hematoma volume affects the accuracy of computed tomographic angiography 'spot sign' in predicting hematoma expansion after acute intracerebral hemorrhage. Eur Neurol 2011, 65:150-155.
14. Park SY, Kong MH, Kim JH, Kang DS, Song KY, Huh SK Role of 'spot sign' on CT angiography to predict hematoma expansion in spontaneous intracerebral hemorrhage. J Korean Neurosurg Soc 2010, 48:399-405.
15. Delgado Almandoz JE, Yoo AJ, Stone MJ, et al. Systematic characterization of the computed tomography angiography spot sign in primary intracerebral hemorrhage identifies patients at highest risk for hematoma expansion: the spot sign score. Stroke 2009, 40:2994-3000.
16. Delgado Almandoz JE, Yoo AJ, Stone MJ, et al. The spot sign score in primary intracerebral hemorrhage identifies patients at highest risk of in-hospital mortality and poor outcome among survivors. Stroke 2010, 41:54-60.
17. Broderick JP, Brott TG, Duldner JE, Tomsick T, Huster G Volume of intracerebral hemorrhage. A powerful and easy-to-use predictor of 30-day mortality. Stroke 1993, 24:987-993.
18. Kothari RU, Brott T, Broderick JP, et al. The ABCs of measuring intracerebral hemorrhage volumes. Stroke 1996, 27:1304-1305.
19. Kosior JC, Idris S, Dowlatshahi D, et al. Quantomo: validation of a computer-assisted methodology for the volumetric analysis of intracerebral haemorrhage. Int J Stroke 2011, 6:302-305.
20. Thompson AL, Kosior JC, Gladstone DJ, et al. Defining the CT angiography 'spot sign' in primary intracerebral hemorrhage. Can J Neurol Sci 2009, 36:456-461.
21. Dowlatshahi D, Demchuk AM, Flaherty ML, Ali M, Lyden PL, Smith EE Defining hematoma expansion in intracerebral hemorrhage: Relationship with patient outcomes. Neurology 2011, 76:1238-1244.
22. Kowada M, Yamaguchi K, Matsuoka S, Ito Z Extravasation of angiographic contrast material in hypertensive intracerebral hemorrhage. J Neurosurg 1972, 36:471-473.
23. Murai Y, Ikeda Y, Teramoto A, Tsuji Y Magnetic resonance imaging-documented extravasation as an indicator of acute hypertensive intracerebral hemorrhage. J Neurosurg 1998, 88:650-655.
24. Gazzola S, Aviv RI, Gladstone DJ, et al. Vascular and nonvascular mimics of the CT angiography " spot sign" in patients with secondary intracerebral hemorrhage. Stroke 2008, 39:1177-1183.
25. Becker KJ, Baxter AB, Bybee HM, Tirschwell DL, Abouelsaad T, Cohen WA Extravasation of radiographic contrast is an independent predictor of death in primary intracerebral hemorrhage. Stroke 1999, 30:2025-2032.
26. Ederies A, Demchuk A, Chia T, Gladstone DJ, et al. Postcontrast CT extravasation is associated with hematoma expansion in CTA spot negative patients. Stroke 2009, 40:1672-1676.
27. Hallevi H, Abraham AT, Barreto AD, Grotta JC, Savitz SI The spot sign in intracerebral hemorrhage: the importance of looking for contrast extravasation. Cerebrovasc Dis 2010, 29:217-220.
28. Chakraborty S, Blacquiere D, Lum C, Stotts G Dynamic nature of the CT angiographic " spot sign" Br J Radiol 2010, 83:e216-e219.
29. d'Esterre CD, Chia TL, Jairath A, Lee TY, Symons SP, Aviv RI Early rate of contrast extravasation in patients with intracerebral hemorrhage. AJNR Am J Neuroradiol 2011, 32:1879-1884.
30. Diringer MN, Skolnick BE, Mayer SA, et al. Thromboembolic events with recombinant activated factor VII in spontaneous intracerebral hemorrhage: results from the Factor Seven for Acute Hemorrhagic Stroke (FAST) trial. Stroke 2010, 41:48-53.