Lipid-laden bronchoalveolar macrophages in asthma and chronic cough

Respiratory Medicine

Volumn 108, Issue 1, 2014, Pages 71-77

  Gibeon, D ^a,b   Zhu, J ^a   Sogbesan, A ^b   Banya, W ^a,b   Rossios, C ^a   Saito, J ^a   Rocha, J P ^a,b   Hull, J H ^b   Menzies Gow, A N ^b   Bhavsar, P K ^a   Chung, K F ^a,b  

^a NATIONAL HEART AND LUNG INSTITUTE   (United Kingdom)

^b ROYAL BROMPTON AND HAREFIELD NHS FOUNDATION TRUST   (United Kingdom)

Author keywords

Asthma; Cough; Lipid laden macrophages

Indexed keywords

LIPID;

ADULT; ARTICLE; ASTHMA; BODY MASS; CHRONIC COUGH; CLINICAL ARTICLE; CONTROLLED STUDY; DISEASE SEVERITY; FEMALE; FORCED EXPIRATORY VOLUME; FORCED VITAL CAPACITY; GASTROESOPHAGEAL REFLUX; HUMAN; HUMAN CELL; LIPID LADEN MACROPHAGE; LUNG ALVEOLUS MACROPHAGE; LUNG LAVAGE; MALE; PRIORITY JOURNAL; RESPIRATORY TRACT INFLAMMATION;

ASTHMA; COUGH; LIPID-LADEN MACROPHAGES;

ADULT; ASTHMA; BODY MASS INDEX; BRONCHOALVEOLAR LAVAGE FLUID; BRONCHOSCOPY; CASE-CONTROL STUDIES; CELL COUNT; CHRONIC DISEASE; COUGH; FEMALE; HUMANS; LIPIDS; MACROPHAGES, ALVEOLAR; MALE; MIDDLE AGED; OBESITY; RISK FACTORS; SEVERITY OF ILLNESS INDEX;

EID: 84893663445     PISSN: 09546111     EISSN: 15323064     Source Type: Journal    
DOI: 10.1016/j.rmed.2013.10.005     Document Type: Article

References (33)

1. N.E. Alexis, J. Soukup, S. Nierkens, and S. Becker Association between airway hyperreactivity and bronchial macrophage dysfunction in individuals with mild asthma Am J Physiol Lung Cell Mol Physiol 280 2 2001 Feb L369 L375
2. J.L. Simpson, P.G. Gibson, I.A. Yang, J. Upham, A. James, and P.N. Reynolds et al. Impaired macrophage phagocytosis in non-eosinophilic asthma Clin Exp Allergy 43 1 2013 Jan 29 35
3. A.M. Fitzpatrick, F. Holguin, W.G. Teague, and L.A. Brown Alveolar macrophage phagocytosis is impaired in children with poorly controlled asthma J Allergy Clin Immunol 121 6 2008 Jun 1372-8, 1378
4. A.M. Fitzpatrick, W.G. Teague, L. Burwell, M.S. Brown, and L.A. Brown Glutathione oxidation is associated with airway macrophage functional impairment in children with severe asthma Pediatr Res 69 2 2011 Feb 154 159
5. D.M. Schrijvers, G.R. De Meyer, M.M. Kockx, A.G. Herman, and W. Martinet Phagocytosis of apoptotic cells by macrophages is impaired in atherosclerosis Arterioscler Thromb Vasc Biol 25 6 2005 Jun 1256 1261
6. I. Rahman, D. Morrison, K. Donaldson, and W. MacNee Systemic oxidative stress in asthma, COPD, and smokers Am J Respir Crit Care Med 154 4 Pt 1 1996 Oct 1055 1060
7. C.J. De, A. Hernandez-Hernandez, M.C. Rodriguez, J.L. Sardina, M. Llanillo, and J. Sanchez-Yague Comparison of changes in erythrocyte and platelet phospholipid and fatty acid composition and protein oxidation in chronic obstructive pulmonary disease and asthma Platelets 18 1 2007 Feb 43 51
8. K. Shibuya, M. Tajima, J. Yamate, T. Saitoh, and S. Sannai Genesis of pulmonary foam cells in rats with diet-induced hyper beta-lipoproteinaemia Int J Exp Pathol 72 4 1991 Aug 423 435
9. V. Hadda, and G.C. Khilnani Lipoid pneumonia: an overview Expert Rev Respir Med 4 6 2010 Dec 799 807
10. R. Adams, R. Ruffin, and D. Campbell The value of the lipid-laden macrophage index in the assessment of aspiration pneumonia Aust N Z J Med 27 5 1997 Oct 550 553
11. K. Parameswaran, M. Anvari, A. Efthimiadis, D. Kamada, F.E. Hargreave, and C.J. Allen Lipid-laden macrophages in induced sputum are a marker of oropharyngeal reflux and possible gastric aspiration Eur Respir J 16 6 2000 Dec 1119 1122
12. P. Bostrom, B. Magnusson, P.A. Svensson, O. Wiklund, J. Boren, and L.M. Carlsson et al. Hypoxia converts human macrophages into triglyceride-loaded foam cells Arterioscler Thromb Vasc Biol 26 8 2006 Aug 1871 1876
13. M.J. Reasor, K.L. Hastings, and R.G. Ulrich Drug-induced phospholipidosis: issues and future directions Expert Opin Drug Saf 5 4 2006 Jul 567 583
14. W. Jacobson, S. Stewart, G.A. Gresham, and M.J. Goddard Effect of amiodarone on the lung shown by polarized light microscopy Arch Pathol Lab Med 121 12 1997 Dec 1269 1271
15. J.R. Wright, and D.C. Youmans Degradation of surfactant lipids and surfactant protein A by alveolar macrophages in vitro Am J Physiol 268 5 Pt 1 1995 May L772 L780
16. Proceedings of the ATS workshop on refractory asthma: current understanding, recommendations, and unanswered questions Am J Respir Crit Care Med 162 2001 2341 2351
17. R.W. Corwin, and R.S. Irwin The lipid-laden alveolar macrophage as a marker of aspiration in parenchymal lung disease Am Rev Respir Dis 132 3 1985 Sep 576 581
18. J.L. Colombo, and T.K. Hallberg Recurrent aspiration in children: lipid-laden alveolar macrophage quantitation Pediatr Pulmonol 3 2 1987 Mar 86 89
19. H.J. Schunemann, P. Muti, J.L. Freudenheim, D. Armstrong, R. Browne, and R.A. Klocke et al. Oxidative stress and lung function Am J Epidemiol 146 11 1997 Dec 939 948
20. J.B. Sedgwick, Y.S. Hwang, H.A. Gerbyshak, H. Kita, and W.W. Busse Oxidized low-density lipoprotein activates migration and degranulation of human granulocytes Am J Respir Cell Mol Biol 29 6 2003 Dec 702 709
21. B.E. Brown, E. Nobecourt, J. Zeng, A.J. Jenkins, K.A. Rye, and M.J. Davies Apolipoprotein A-I glycation by glucose and reactive aldehydes alters phospholipid affinity but not cholesterol export from lipid-laden macrophages PLoS One 8 5 2013 May e65430
22. O. Sacco, M. Silvestri, F. Sabatini, R. Sale, G. Moscato, and P. Pignatti et al. IL-8 and airway neutrophilia in children with gastroesophageal reflux and asthma-like symptoms Respir Med 100 2 2006 Feb 307 315
23. M.Y. Kazachkov, M.S. Muhlebach, C.A. Livasy, and T.L. Noah Lipid-laden macrophage index and inflammation in bronchoalveolar lavage fluids in children Eur Respir J 18 5 2001 Nov 790 795
24. I.K. Carney, P.G. Gibson, K. Murree-Allen, N. Saltos, L.G. Olson, and M.J. Hensley A systematic evaluation of mechanisms in chronic cough Am J Respir Crit Care Med 156 1 1997 Jul 211 216
25. M.L. Bauer, and R.K. Lyrene Chronic aspiration in children: evaluation of the lipid-laden macrophage index Pediatr Pulmonol 28 2 1999 Aug 94 100
26. M.E. Furuya, V. Moreno-Cordova, J.L. Ramirez-Figueroa, M.H. Vargas, G. Ramon-Garcia, and D.H. Ramirez-San Juan Cutoff value of lipid-laden alveolar macrophages for diagnosing aspiration in infants and children Pediatr Pulmonol 42 5 2007 May 452 457
27. R. Kitz, H.J. Boehles, M. Rosewich, and M.A. Rose Lipid-laden alveolar macrophages and pH monitoring in gastroesophageal reflux-related respiratory symptoms Pulm Med 2012 2012 673637
28. R. Rosen, J. Fritz, A. Nurko, D. Simon, and S. Nurko Lipid-laden macrophage index is not an indicator of gastroesophageal reflux-related respiratory disease in children Pediatrics 121 4 2008 Apr e879 e884
29. D. Hayes Jr., S.S. Kirkby, K. McCoy, H.M. Mansour, M. Khosravi, H. Strawbridge, and J.D. Tobias Reduction of lipid-laden macrophage index after laparoscopic Nissen fundoplication in cystic fibrosis patients after lung transplantation Clin Trasnplant 27 1 2013 Sep 121 125
30. G. Hoskins, C. McCowan, R.G. Neville, G.E. Thomas, B. Smith, and S. Silverman Risk factors and costs associated with an asthma attack Thorax 55 1 2000 Jan 19 24
31. D. Koksal, B. Ozkan, C. Simsek, A.S. Koksal, Y. Agackyran, and N. Sasmaz Lipid-laden alveolar macrophage index in sputum is not useful in the differential diagnosis of pulmonary symptoms secondary to gastroesophageal reflux Arch Med Res 36 5 2005 Sep 485 489
32. A.M. Wilson, P. Nair, F.E. Hargreave, A.E. Efthimiadis, M. Anvari, and C.J. Allen Lipid and smoker's inclusions in sputum macrophages in patients with airway diseases Respir Med 105 11 2011 Nov 1691 1695
33. Y. Ding, P.M. Simpson, D.E. Schellhase, A.F. Tryka, L. Ding, and D.M. Parham Limited reliability of lipid-laden macrophage index restricts its use as a test for pulmonary aspiration: comparison with a simple semiquantitative assay Pediatr Dev Pathol 5 6 2002 Nov 551 558