Lipoid pneumonia: An overview

Expert Review of Respiratory Medicine

Volumn 4, Issue 6, 2010, Pages 799-807

  Hadda, Vijay ^a   Khilnani, Gopi C ^a  

^a ALL INDIA INSTITUTE OF MEDICAL SCIENCES   (India)

Author keywords

endogenous lipoid pneumonia; exogenous lipoid pneumonia; ipoid pneumonia; lipid laden macrophages

Indexed keywords

ANTIBIOTIC AGENT; ANTIINFLAMMATORY AGENT; CORTICOSTEROID; SESAME SEED OIL;

ASPIRATION BIOPSY; ASPIRATION PNEUMONIA; BRONCHIOLITIS OBLITERANS; CLINICAL FEATURE; COMPUTER ASSISTED TOMOGRAPHY; COUGHING; DELAYED DIAGNOSIS; DIAGNOSTIC ERROR; DYSPNEA; ENDOGENOUS LIPOID PNEUMONIA; ERYTHROCYTE SEDIMENTATION RATE; EXOGENOUS LIPOID PNEUMONIA; FEVER; FOREIGN BODY; HEMOPTYSIS; HUMAN; HYPERCALCEMIA; LUNG BIOPSY; LUNG LAVAGE; LUNG SARCOIDOSIS; MACROPHAGE; NONHUMAN; PNEUMOMEDIASTINUM; PNEUMOTHORAX; REVIEW; RISK FACTOR; SPUTUM; SYMPTOM; THORAX PAIN; THORAX RADIOGRAPHY; TUBERCULOSIS; WHEEZING;

EID: 78650058275     PISSN: 17476348     EISSN: 17476356     Source Type: Journal    
DOI: 10.1586/ers.10.74     Document Type: Review

References (97)

1. Laughlen GF. Studies on pneumonia following naso-pharyngeal injection of oil. Am. J. Pathol. 1, 407-414 (1925).
2. Adams FD, Pittman H. Lipid pneumonia of right middle lobe. N. Engl. J. Med. 241(15), 579-582 (1949).
3. Baron E. Lipoid pneumonia due to the use of mineral oil as a laxative. VA Med. Mon. 77(9), 448-450 (1950).
4. Berg R Jr, Burford TH. Pulmonary paraffnoma (lipoid pneumonia); a critical study. J. Thorac. Surg. 20(3), 418-428 (1950).
5. No authors listed. WEEKLY clinicopathological exercise: lipoid pneumonia (paraffnoma of lung). N. Engl J. Med. 246(23), 909-912 (1952).
6. Hoffman LR, Yen EH, Kanne JP, Effmann EL, Gibson RL, Van Niel CW. Lipoid pneumonia due to Mexican folk remedies: cultural barriers to diagnosis. Arch. Pediatr. Adolesc. Med. 159(11), 1043-1048 (2005).
7. Costa AS, Noya R, Calvo TC, Severo R, Afonso A. [Exogenous lipoid pneumonia-case report]. Rev. Port. Pneumol. 11(6), 567-572 (2005).
8. Chauveau R, Medart L, Ghaye B. [Exogenous lipoid pneumonia: a simple diagnosis?]. Rev. Med. Liege. 60(10), 799-804 (2005).
9. Gondouin A, Manzoni P, Ranfaing E et al. Exogenous lipid pneumonia: a retrospective multicentre study of 44 cases in France. Eur. Respir. J. 9(7), 1463-1469 (1996).
10. Bhagat R, Holmes IH, Kulaga A, Murphy F, Cockcroft DW. Self-injection with olive oil. A cause of lipoid pneumonia. Chest 107(3), 875-876 (1995).
11. Hirata M, Morita M, Maebou A, Hara H, Yoshimoto T, Hirao F. [A case of exogenous lipoid pneumonia probably due to domestic insecticide]. Nihon Kyobu Shikkan Gakkai Zasshi 31(10), 1317-1321 (1993).
12. Alaminos Garcia P, Colodro Ruiz A, Menduina Guillen MJ, Banez Sanchez F, Perez Chica G. [Exogenous lipoid pneumonia. Presentation of a new case]. An. Med. Interna. 22(6), 283-284 (2005).
13. Mydlowski T, Malong P, Wiatr E. [Exogenous lipoid pneumonia-case report]. Pneumonol. Alergol. Pol. 72(5-6), 214-216 (2004).
14. Brown AL. Lipoid pneumonia resulting from a dermoid cyst; case report. J. Thorac. Surg 20(2), 260-265 (1950).
15. Baron SE, Haramati LB, Rivera VT. Radiological and clinical fndings in acute and chronic exogenous lipoid pneumonia. J. Thorac. Imaging 18(4), 217-224 (2003).
16. Meltzer E, Guranda L, Perelman M, Krupsky M, Vassilenko L, Sidi Y Lipoid pneumonia: a preventable form of drug-induced lung injury Eur. J. Intern. Med. 16(8), 615-617 (2005).
17. Kitchen JM, O'Brien DE, McLaughlin AM. Perils of fre eating. An acute form of lipoid pneumonia or fre eater's lung. Thorax 63 (5), 401, 39 (2008).
18. Seaton A. Lipoid pneumonia in a fre breather. Occup. Med. (Lond.) 60(5), 406 (2010).
19. Becton DL, Lowe JE, Falletta JM. Lipoid pneumonia in an adolescent girl secondary to use of lip gloss. J. Pediatr. 105(3), 421-423 (1984).
20. Gurell MN, Kottmann RM, Xu H, Sime PJ. Exogenous lipoid pneumonia: an unexpected complication of substance abuse. Ann. Intern. Med. 149(5), 364-365 (2008).
21. Hadda V, Khilnani GC, Bhalla AS, Mathur S. Lipoid pneumonia presenting as non resolving community acquired pneumonia: a case report. Cases J. 2, 9332 (2009).
22. Annobil SH, Benjamin B, Kameswaran M, Khan AR. Lipoid pneumonia in children following aspiration of animal fat (ghee). Ann. Trop. Paediatr. 11(1), 87-94 (1991).
23. Hugosson CO, Riff EJ, Moore CC, Akhtar M, Tufenkeji HT. Lipoid pneumonia in infants: a radiological-pathological study. Pediatr. Radiol. 21(3), 193-197 (1991).
24. Balakrishnan S. Lipoid pneumonia in infants and children in South India. Br. Med. J. 4(5888), 329-331 (1973).
25. de Oliveira GA, Del Caro SR, Bender Lamego CM, Mercon de Vargas PR, Vervloet VE. Radiographic plain flm and CT fndings in lipoid pneumonia in infants following aspiration of mineral oil used in the treatment of partial small bowel obstruction by Ascaris lumbricoides. Pediatr. Radiol. 15(3), 157-160 (1985).
26. McDonald JR, Hodgson CH. The problem of lipoid pneumonia or granuloma of the lung. Med. Clin. North Am. New York 989-996 (1954).
27. Wolfson BJ, Allen JL, Panitch HB, Karmazin N. Lipid aspiration pneumonia due to gastroesophageal refux. A complication of nasogastric lipid feedings. Pediatr. Radiol. 19(8), 545-547 (1989).
28. Fournier P, Aerts J, Damade R, Pasquier P. [A rare cause of infammatory syndrome: lipoid pneumonia]. Presse Med. 19(38), 1768-1769 (1990).
29. Aibar Arregui MA, Laborda Ezquerra K, Conget Lopez F. [Lipoid pneumonia related to an accidental aspiration of gas-oil]. An. Med. Interna. 24(4), 187-189 (2007).
30. Bernabeu Mora R, Mendez Martinez P, Abellan Martinez MC, Polo Garcia LA, Lorenzo Cruz M, Sanchez Gascon F. [Acute lipoid pneumonia caused by accidental aspiration of vaseline used in nasogastric intubation]. Arch. Bronconeumol. 36(8), 485-487 (2000).
31. Facon D, Coumbaras J, Bigot E, Bahlouli F, Boissonnas A, Bellin MF. Acute hydrocarbon pneumonia after white spirit aspiration: sequential HRCT fndings. Eur. Radiol. 15(1), 31-33 (2005).
32. Subramanian S, Kherdekar SS, Babu PG, Christianson CS. Lipoid pneumonia with Cryptococcus neoformans colonisation. Thorax 37(4), 319-320 (1982).
33. Simmons A, Rouf E, Whittle J. Not your typical pneumonia: a case of exogenous lipoid pneumonia. J. Gen. Intern. Med. 22(11), 1613-1616 (2007).
34. Hampton AO, Bickham CE Jr, Winship T. Lipoid pneumonia. Am. J. Roentgenol. Radium Ther. Nucl. Med. 73(6), 938-949 (1955).
35. Felson B, Ralaisomay G. Carcinoma of the lung complicating lipoid pneumonia. Am. J. Roentgenol. 141(5), 901-907 (1983).
36. Lipinski JK, Weisbrod GL, Sanders DE. Exogenous lipoid pneumonitis: pulmonary patterns. AJR Am. J. Roentgenol. 136(5), 931-934 (1981).
37. Haas C, Lebas FX, Le Jeunne C, Lowenstein W, Durand H, Hugues FC. [Pneumopathies caused by inhalation of hydrocarbons: apropos of 3 cases]. Ann. Med. Interne (Paris).151(6), 438-447 (2000).
38. Marchiori E, Zanetti G, Mano CM, Irion KL, Daltro PA, Hochhegger B. Lipoid pneumonia in 53 patients after aspiration of mineral oil: comparison of high-resolution computed tomography fndings in adults and children. J. Comput. Assist. Tomogr. 34(1), 9-12 (2010).
39. Betancourt SL, Martinez-Jimenez S, Rossi SE, Truong MT, Carrillo J, Erasmus JJ. Lipoid pneumonia: spectrum of clinical and radiologic manifestations. AJR Am. J. Roentgenol. 194(1), 103-109 (2010).
40. Lipinski JK, Weisbrod GL, Sanders DE. Exogenous lipoid pneumonitis. J. Can. Assoc. Radiol. 31(2), 92-98 (1980).
41. Kennedy JD, Costello P, Balikian JP, Herman PG. Exogenous lipoid pneumonia. AJR Am. J. Roentgenol. 136(6), 1145-1149 (1981).
42. Brechot JM, Buy JN, Laaban JP, Rochemaure J. Computed tomography and magnetic resonance fndings in lipoid pneumonia. Thorax 46(10), 738-739 (1991).
43. Weinberg I, Fridlender ZG. Exogenous lipoid pneumonia caused by paraffn in an amateur fre breather. Occup. Med. (Lond.) 60(3), 234-235 (2010).
44. Genereux GP. Lipids in the lungs: radio logic-pathologic correlation. J. Can. Assoc. Radiol. 21(1), 2-15 (2010).
45. Antico A, Gabrielli M, DAversa C, Musa M, Torri T. Lipoid pneumonia: a case of cavitary bilateral nodular opacity Monaldi Arch. Chest Dis. 51(4), 296-298 (1996).
46. Bandla HP, Davis SH, Hopkins NE. Lipoid pneumonia: a silent complication of mineral oil aspiration. Pediatrics 103(2), E19 (1999).
47. Miller GJ, Ashcroft MT, Beadnell HM, Wagner JC, Pepys J. The lipoid pneumonia of blackfat tobacco smokers in Guyana. Q. J. Med. 40(160), 457-470 (1971).
48. Carrillon Y, Tixier E, Revel D, Cordier JF. MR diagnosis of lipoid pneumonia. J. Comput. Assist. Tomogr. 12(5), 876-877 (1988).
49. Laurent F, Philippe JC, Vergier B et al. Exogenous lipoid pneumonia: HRCT, MR, and pathologic fndings. Eur. Radiol. 9(6), 1190-1196 (1999).
50. Carette MF, Grivaux M, Monod B, Capeau F, Lebreton C, Bigot JM. MR fndings in lipoid pneumonia. AJR Am. J. Roentgenol. 153(5), 1097-1098 (1989).
51. Brody JS, Levin B. Interlobular septa thickening in lipid pneumonia. Am. J. Roentgenol. Radium Ther. Nucl. Med. 88, 1061-1069 (1962).
52. Davis EW, Hampton AO, Bickham CE, Winship T. Lipoid pneumonia simulating tumor. J. Thorac. Surg. 28(2), 212-219 (1954).
53. Scully RE, Galdabini JJ, McNeely BU. Case records of the Massachusetts General Hospital. Weekly clinicopathological exercises. Case 22-1977. N. Engl. J. Med. 296(22), 1279-1287 (1977).
54. Tahon F, Berthezene Y, Hominal S et al. Exogenous lipoid pneumonia with unusual CT pattern and FDG positron emission tomography scan fndings. Eur. Radiol. 12(Suppl. 3), S171-S173 (2002).
55. Kanaji N, Bandoh S, Takano K et al. Positron emission tomography-positive squalene-induced lipoid pneumonia confrmed by gas chromatography-mass spectrometry of bronchoalveolar lavage fuid. Am. J. Med. Sci. 335(4), 310-314 (2008).
56. Casey JF. Chronic cor pulmonale associated with lipoid pneumonia. JAMA 177, 896-898 (1961).
57. Domej W, Mitterhammer H, Stauber R, Kaufmann P, Smolle KH. Successful outcome after intravenous gasoline injection. J. Med. Toxicol. 3(4), 173-177 (2007).
58. Guerguerian AM, Lacroix J. Pulmonary injury after intravenous hydrocarbon injection. Paediatr. Child Health 5(8), 471-472 (2000).
59. Bratton L, Haddow JE. Ingestion of charcoal lighter fuid. J. Pediatr. 87(4), 633-636 (1975).
60. Russo R, Chiumello D, Cassani G, Maiocchi G, Gattinoni L. Case of exogenous lipoid pneumonia: steroid therapy and lung lavage with an emulsifer. Anesthesiology 104(1), 197-198 (2006).
61. Parameswaran K, Anvari M, Efthimiadis A, Kamada D, Hargreave FE, Allen CJ. Lipid-laden macrophages in induced sputum are a marker of oropharyngeal refux and possible gastric aspiration. Eur. Respir. J. 16(6), 1119-1122 (2000).
62. Levade T, Salvayre R, Dongay G et al. Chemical analysis of the bronchoalveolar washing fuid in the diagnosis of liquid paraffn pneumonia. J. Clin. Chem. Clin. Biochem. 25(1), 45-48 (1987).
63. Gattuso P, Reddy VB, Castelli MJ. Exogenous lipoid pneumonitis due to Vicks Vaporub inhalation diagnosed by fne needle aspiration cytology. Cytopathology 2(6), 315-316 (1991).
64. Ferretti GR, Jankowski A, Rodiere M, Brichon PY, Brambilla C, Lantuejoul S. CT-guided biopsy of nonresolving focal air space consolidation. J. Thorac. Imaging 23(1), 7-12 (2008).
65. de Albuquerque Filho AP. Exogenous lipoid pneumonia: importance of clinical history to the diagnosis. J. Bras. Pneumol. 32(6), 596-598 (2006).
66. Knauer-Fischer S, Ratjen F. Lipid-laden macrophages in bronchoalveolar lavage fuid as a marker for pulmonary aspiration. Pediatr. Pulmonol. 27(6), 419-422 (1999).
67. Kazachkov MY, Muhlebach MS, Livasy CA, Noah TL. Lipid-laden macrophage index and infammation in bronchoalveolar lavage fuids in children. Eur. Respir. J. 18(5), 790-795 (2001).
68. McDonald JR, Harrington SW, Clagett OT. Obstructive pneumonitis of neoplastic origin; an interpretation of one form of so-called atelectasis and its correlation according to presence of absence of sputum. J. Thorac. Surg 18(1), 97-112 (1949).
69. Gaerte SC, Meyer CA, Winer-Muram HT, Tarver RD, Conces DJ Jr. Fat-containing lesions of the chest. Radiographics 22, S61-S78 (2002).
70. Tamura A, Hebisawa A, Fukushima K, Yotsumoto H, Mori M. Lipoid pneumonia in lung cancer: radiographic and pathological features. Jpn J. Clin. Oncol. 28(8), 492-496 (1998).
71. Burke M, Fraser R. Obstructive pneumonitis: a pathologic and pathogenetic reappraisal. Radiology 166(3), 699-704 (1988).
72. Cohen AB, Cline MJ. In vitro studies of the foamy macrophage of postobstructive endogenous lipoid pneumonia in man. Am. Rev. Respir. Dis. 106(1), 69-78 (1972).
73. Itoh Y, Segawa H, Kito K et al. Lipoid pneumonia with chronic myelomonocytic leukemia. Pathol. Res. Pract. 205(2), 143-147 (2009).
74. Nicholson AG, Wells AU, Hooper J, Hansell DM, Kelleher A, Morgan C. Successful treatment of endogenous lipoid pneumonia due to Niemann-Pick Type B disease with whole-lung lavage. Am. J. Respir. Crit. Care Med. 165(1), 128-131 (2002).
75. Berghaus TM, Haeckel T, Wagner T, von Scheidt W, Schwaiblmair MG. Endogenous lipoid pneumonia associated with primary sclerosing cholangitis. Lancet 369(9567), 1140 (2007).
76. Au WY, Lie AK, Cheng VC, Cheng LC, Wang EP, Wong CF. Successful lung transplantation for post-BMT bronchiolitis obliterans and lipoid pneumonia associated with atypical mycobacterium and aspergillosis infection. J. Heart Lung Transplant. 26(8), 870-872 (2007).
77. Meyer EC. [Necrotizing granulomatosis with cholesterol pneumonitis diagnosed during life]. Dapim Refuiim. 24(2), 175-178 (1965).
78. Barta Z, Szabo GG, Bruckner G, Szegedi G. Endogenous lipoid pneumonia associated with undifferentiated connective tissue disease (UCTD). Med. Sci. Monit. 7(1), 134-136 (2001).
79. Verbeken EK, Demedts M, Vanwing J, Deneffe G, Lauweryns JM. Pulmonary phospholipid accumulation distal to an obstructed bronchus. A morphologic study. Arch. Pathol. Lab. Med. 113(8), 886-890 (1989).
80. Taki T, Nakazima T, Emi Y, Konishi Y, Hayashi A, Matsumoto M. Accumulation of surfactant phospholipids in lipid pneumonia induced with methylnaphthalene. Lipids 21(9), 548-552 (1986).
81. Tolle A, Kolleck I, Schlame M, Wauer R, Stevens PA, Rustow B. Effect of hyperoxia on the composition of the alveolar surfactant and the turnover of surfactant phospholipids, cholesterol, plasmalogens and vitamin E. Biochim. Biophys. Acta 1346(2), 198-204 (1997).
82. Evans AJ, Sawyez CG, Wolfe BM, Connelly PW, Maguire GF, Huff MW. Evidence that cholesteryl ester and triglyceride accumulation in J774 macrophages induced by very low density lipoprotein subfractions occurs by different mechanisms. J. Lipid Res. 34(5), 703-717 (1993).
83. Spickard A 3rd, Hirschmann JV. Exogenous lipoid pneumonia. Arch. Intern. Med. 154(6), 686-692 (1994).
84. Khilnani GC, Hadda V. Lipoid pneumonia: an uncommon entity. Indian J. Med. Sci. 63(10), 474-480 (2009).
85. Marks MI, Chicoine L, Legere G, Hillman E. Adrenocorticosteroid treatment of hydrocarbon pneumonia in children-a cooperative study. J. Pediatr. 81(2), 366-369 (1972).
86. Chin NK, Hui KP, Sinniah R, Chan TB. Idiopathic lipoid pneumonia in an adult treated with prednisolone. Chest 105(3), 956-957 (1994).
87. Amato GM, Novara V, Amato G. [Lipid pneumonia. Favorable outcome after treatment with intravenous immunoglobulins, steroids, cephalosporins]. Minerva Pediatr. 49(4), 163-169 (1997).
88. Chang HY, Chen CW, Chen CY et al. Successful treatment of diffuse lipoid pneumonitis with whole lung lavage. Thorax 48(9), 947-948 (1993).
89. Ciravegna B, Sacco O, Moroni C et al. Mineral oil lipoid pneumonia in a child with anoxic encephalopathy: treatment by whole lung lavage. Pediatr. Pulmonol. 23(3), 233-237 (1997).
90. Sias SM, Ferreira AS, Daltro PA, Caetano RL, Moreira Jda S, Quirico-Santos T. Evolution of exogenous lipoid pneumonia in children: clinical aspects, radiological aspects and the role of broncho alveolar lavage. J. Bras. Pneumol. 35(9), 839-845 (2009).
91. Sias SM, Daltro PA, Marchiori E et al. Clinic and radiological improvement of lipoid pneumonia with multiple bronchoalveolar lavages. Pediatr. Pulmonol 44(4), 309-315 (2009).
92. Bellenot F, Regnard JF, Babo P, Rojas-Miranda A, Couffnhal JC, Levasseur P. [Pseudotumoral lipid pneumopathies. Apropos of six cases]. Ann. Chir. 45 (8), 715-718 (1991).
93. Greenberger PA, Katzenstein AL. Lipid pneumonia with atypical mycobacterial colonization. Association with allergic bronchopulmonary aspergillosis. Arch. Intern. Med. 143(10), 2003-2005 (1983).
94. Dixon C, Bolivar R, Katz R, McMurtrey M. Lipoid pneumonia and Mycobacterium fortuitum pulmonary infection: successful treatment with sulfsoxazole. Tex. Med. 81(3), 57-60 (1985).
95. Greenaway TM, Caterson ID. Hypercalcemia and lipoid pneumonia. Aust. NZ J. Med. 19(6), 713-715 (1989).
96. Keshishian JM, Abad JM, Fuchs M. Lipoid pneumonia. Review with a report of a case of carcinoma occurring within an area of lipoid pneumonia. Ann. Thorac. Surg. 7(3), 231-234 (1969).
97. Breton JL, Jeffredo Y, Ranfaing E, Clement F, Faure E, Garnier G. [Associated lipid pneumonia and bronchiolo-alveolar carcinoma]. Rev. Mal. Respir. 11(6), 596-598 (1994).