Effect of amiodarone on the lung shown by polarized light microscopy

Archives of Pathology and Laboratory Medicine

Volumn 121, Issue 12, 1997, Pages 1269-1271

  Jacobson, W ^a   Stewart, Susan ^a   Gresham, G A ^b   Goddard, M J ^a  

^a ADDENBROOKE S HOSPITAL   (United Kingdom)

^b PAPWORTH HOSPITAL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

AMIODARONE;

ARTICLE; CLINICAL EXAMINATION; FROZEN SECTION; FUNCTIONAL ASSESSMENT; HEART ARRHYTHMIA; HUMAN; HUMAN CELL; HUMAN TISSUE; LIPID STORAGE; LUNG FUNCTION; LUNG PARENCHYMA; MICROSCOPY;

AMIODARONE; ANTI-ARRHYTHMIA AGENTS; ARTERIOLES; DOSE-RESPONSE RELATIONSHIP, DRUG; ENDOTHELIUM, VASCULAR; FROZEN SECTIONS; HUMANS; LIPIDS; LUNG; MACROPHAGES, ALVEOLAR; MALE; MICROSCOPY, POLARIZATION; MIDDLE AGED; PHOSPHOLIPASES; PHOSPHORUS; PULMONARY ALVEOLI; PULMONARY SURFACTANTS; VENULES;

EID: 0031421284     PISSN: 00039985     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (14)

1. Podrid J. Amiodarone: réévaluation of an old drug. Ann Intern Med. 1995;122:689-700.
2. Perry JC, Fenrich AL, Hulse JE, Triedman JK, Friedman RA, Lamberti JJ. Pediatric use of intravenous amiodarone: efficacy and safety in critically ill patients from a multicenter protocol. J. Am Coll Cardiol. 1996;27:1246-1250.
3. Heath MF, Costa-Jussa FR, Jacobs JM, Jacobson W. The induction of pulmonary phospholipidosis and the inhibition of lysosomal phospholipases by amiodarone. Br J Exp Palhol. 1985;66:39l-397.
4. Jacobson W, South M, Hughes G, Davies R, Morley C. Trachéal aspirates from neonates during endotracheal intubation: detection of surfactant by polarised light microscopy. J Pediatr. 1988;113:368-372.
5. Jacobson W, Morley CJ, South M. Microscopic observations on trachea! aspirates from ventilated neonates, II: the onset of bronchopulmonary dysplasia and other changes. FurJ. Pediatr. 1992;151:204-207.
6. Rotmensch HH, Liron M, Tupilski M, Laniado S. Possible association of pneumonitis with amiodarone therapy. Am Heart J. 1980;100:412-413.
7. Marchlinski FE, Gausler TS, Waxman HL, Josephson ME. Amiodarone pulmonary toxicity. Am J Intern Med. 1982;97:839-845.
8. Clark HW, Jacobson W. Polarised light microscopy of amniotic fluid: a rapid method to assess fetal lung maturity - a pilot study, J Obstet Cynaecol. 1991;11:307-314.
9. Vrobel TR, Miller PE, Mostow ND, Rakita L. A general overview of amiodarone toxicity: its prevention, detection and management. Prog Cardiovasc Dis. 1989;31:393-426.
10. Martin WJ II, Howard DM. Amiodarone-induced lung toxicity: in vitro evidence of the direct toxicity of the drug. Am J Pathol. 1985;120:344-350.
11. Martin WJ II, Kachel DL, Vilen T, Natarajan V. Mechanism of phospholipidosis in amiodarone pulmonary toxicity. J Pharmacol Exp Ther. 1989;251:272-278.
12. Wilson BD, Lippmann ML. Susceptibility to amiodarone-induced pulmonary toxicity: relationship to the uptake of amiodarone by isolated lung cells. Lung. 1996;174:31-41.
13. Palmeri S, Battisti C, Malandrini A, Federico A. Amiodarone induced lipidosis similar to Niemann-Pick C disease: biochemical and morphogical study. Life Sci. 1998;57:1963-1971.
14. Reasor MJ, Kacew S. An evaluation of possible mechanisms underlying amiodarone-induced pulmonary toxicity. Proc Soc Exp Biol Med. 1966;212:297-304.