Autoantibodies to glutamate receptor antigens in multiple sclerosis and rasmussen's encephalitis

NeuroImmunoModulation

Volumn 21, Issue 4, 2014, Pages 189-194

  Trippe, Juergen ^a   Steinke, Katja ^a   Orth, Angela ^a   Faustmann, Pedro M ^a   Hollmann, Michael ^a   Haase, Claus G ^b  

^a RUHR UNIVERSITY BOCHUM   (Germany)

^b UNIVERSITY OF COLOGNE   (Germany)

Author keywords

Amino 3 hydroxy 5 methyl 4 isoxazole propionic acid; Autoantibody; Autoimmunity; B cell response; Glutamate receptors; Kainate; Multiple sclerosis; N Methyl D aspartate; Rasmussen's encephalitis

Indexed keywords

AUTOANTIBODY; GLUTAMATE RECEPTOR; GLUTAMATE RECEPTOR SUBUNIT A3; GLUTAMATE RECEPTOR SUBUNIT D2; GLUTAMATE RECEPTOR SUBUNIT K2; GLUTAMATE RECEPTOR SUBUNIT N1; GLUTAMATE RECEPTOR SUBUNIT N2C; UNCLASSIFIED DRUG; AMPA RECEPTOR; AUTOANTIGEN; BETA INTERFERON; GLATIRAMER; GLUTAMATE RECEPTOR A3; GLUTAMATE RECEPTOR ANTIBODY; GLUTAMATE RECEPTOR D2; GLUTAMATE RECEPTOR K2; GLUTAMATE RECEPTOR N1; GLUTAMATE RECEPTOR N2B; GLUTAMATE RECEPTOR N2C; HYBRID PROTEIN; N METHYL DEXTRO ASPARTIC ACID RECEPTOR;

ADULT; ANTIBODY AFFINITY; ANTIBODY DETECTION; ANTIBODY RESPONSE; ANTIBODY TITER; ARTICLE; AUTOIMMUNITY; CLINICAL ARTICLE; CONTROLLED STUDY; ENCEPHALITIS; FEMALE; HUMAN; HUMAN CELL; IMMUNOBLOTTING; MALE; MULTIPLE SCLEROSIS; NERVE DEGENERATION; NERVE REGENERATION; PRIORITY JOURNAL; RASMUSSEN SYNDROME; ANTIBODY BLOOD LEVEL; B LYMPHOCYTE; EMBRYO; HEK293 CELL LINE; PARANEOPLASTIC NEUROPATHY; POLYACRYLAMIDE GEL ELECTROPHORESIS; PROTEIN EXPRESSION; PROTEIN ISOLATION; WESTERN BLOTTING;

ADULT; AUTOANTIBODIES; AUTOANTIGENS; ENCEPHALITIS; FEMALE; HUMANS; IMMUNOBLOTTING; MALE; MULTIPLE SCLEROSIS, RELAPSING-REMITTING; RECEPTORS, GLUTAMATE;

EID: 84893660538     PISSN: 10217401     EISSN: 14230216     Source Type: Journal    
DOI: 10.1159/000356519     Document Type: Article

References (33)

1. Wiendl H, Bien CG, Bernasconi P, Fleckenstein B, Elger CE, Dichgans J, Mantegazza R, Melms A: GluR3 antibodies: prevalence in focal epilepsy but no specificity for Rasmussen's encephalitis. Neurology 2001; 57: 1511-1514. (Pubitemid 32995743)
2. Bolton C, Paul C: Glutamate receptors in neuroinflammatory demyelinating disease. Mediators Inflamm 2006; 2006: 93684.
3. Dingledine R, Borges K, Bowie D, Traynelis SF: The glutamate receptor ion channels. Pharmacol Rev 1999; 51: 7-61. (Pubitemid 29113865)
4. Hollmann M, Maron C, Heinemann S: NGlycosylation site tagging suggests a three transmembrane domain topology for the glutamate receptor GluR1. Neuron 1994; 13: 1331-1343.
5. Collingridge GL, Olsen RW, Peters J, Spedding M: A nomenclature for ligand-gated ion channels. Neuropharmacology 2009; 56: 25.
6. Karadottir R, Cavelier P, Bergersen LH, Attwell D: NMDA receptors are expressed in oligodendrocytes and activated in ischaemia. Nature 2005; 438: 1162-1166. (Pubitemid 41831686)
7. Matute C, Alberdi E, Domercq M, Perez-Cerda F, Perez-Samartin A, Sanchez-Gomez MV: The link between excitotoxic oligodendroglial death and demyelinating diseases. Trends Neurosci 2001; 24: 224-230. (Pubitemid 32204379)
8. Matute C, Sanchez-Gomez MV, Martinez-Millan L, Miledi R: Glutamate receptor-mediated toxicity in optic nerve oligodendrocytes. Proc Natl Acad Sci USA 1997; 94: 8830-8835. (Pubitemid 27335125)
9. Matute C, Perez-Cerda F: Multiple sclerosis: novel perspectives on newly forming lesions. Trends Neurosci 2005; 28: 173-175. (Pubitemid 40445522)
10. Micu I, Jiang Q, Coderre E, Ridsdale A, Zhang L, Woulfe J, Yin X, Trapp BD, McRory JE, Rehag R, Zamponi GW, Wang W, Stys PK: NMDA receptors mediate calcium accumulation in myelin during chemical ischaemia. Nature 2006; 439: 988-992. (Pubitemid 43292418)
11. Watson R, Jiang Y, Bermudez I, Houlihan L, Clover L, McKnight K, Cross JH, Hart IK, Roubertie A, Valmier J, Hart Y, Palace J, Beeson D, Vincent A, Lang B: Absence of antibodies to glutamate receptor type 3 (GluR3) in Rasmussen encephalitis. Neurology 2004; 63: 43-50. (Pubitemid 38943777)
12. Dalmau J, Gleichmann AJ, Hughes EG, Rossi JE, Peng X, Lai M, Dessain SK, Rosenfeld MR, Balice-Gordon R, Lynch DR: Anti-NMDAreceptor encephalitis: case series and analysis of the effects of antibodies. Lancet Neurol 2008; 7: 1091-1098.
13. Dalmau J, Tuzun E, Wu HY, Masjuan J, Rossi JE, Voloschin A, Baehring JM, Shimazaki H, Koide R, King D, Mason W, Sansing LH, Dichter ME, Rosenfeld MR, Lynch DR: Paraneoplastic anti-N-methyl-D-aspartate receptor encephalitis associated with ovarian teratoma. Ann Neurol 2007; 61: 25-36. (Pubitemid 46214241)
14. Florance NR, Davis RL, Lam C, Szperka C, Zhou L, Ahmad S, Campen CJ, Moss H, Peter N, Gleichmann AJ, Glaser CA, Lynch DR, Rosenfeld MR, Dalmau J: Anti-N-methyl-D-aspartate receptor (NMDA) encephalitis in children and adolescents. Ann Neurol 2009; 66: 11-18.
15. Irani SR, Bera K, Waters P, Zuliani L, Maxwell S, Zandi MS, Friese MA, Galea I, Kullmann DM, Beeson D, Lang B, Bien CG, Vincent A: N-methyl-D-aspartate antibody encephalitis: temporal progression of the clinical and paraclinical observations in a predominantly nonparaneoplastic disorder of both sexes. Brain 2010; 133: 1655-1667.
16. Rogers SW, Andrews PI, Gahring LC, Whisenand T, Cauley K, Crain B, Hughes TE, Heinemann SF, McNamara JO: Autoantibodies to glutamate receptor GluR3 in Rasmussen's encephalitis. Science 1994; 265: 648-651.
17. Shimokaze T, Kato M, Yoshimura Y, Takahashi Y, Hayasaka K: A case of acute cerebellitis accompanied by autoantibodies against glutamate receptor delta2. Brain Dev 2007; 29: 224-226. (Pubitemid 46283287)
18. Smith T, Groom A, Zhu B, Turski L: Autoimmune encephalomyelitis ameliorated by AMPA antagonists. Nat Med 2000; 6: 15-16.
19. Takahashi Y, Mori H, Mishina M, Watanabe M, Kondo N, Shimomura J, Kubota Y, Matsuda K, Fukushima K, Shiroma N, Akasaka N, Nishida H, Imamura A, Watanabe H, Sugiyama N, Ikezawa M, Fujiwara T: Autoantibodies and cell-mediated autoimmunity to NMDA-type GluRε2 in patients with Rasmussen's encephalitis and chronic progressive epilepsia partialis continua. Epilepsia 2005; 46: 152-158. (Pubitemid 40962139)
20. Vincent A, Bien CG: Anti-NMDA-receptor encephalitis: a cause of psychiatric, seizure, and movement disorders in young adults. Lancet Neurol 2008; 7: 1074-1075.
21. Twyman RE, Gahring LC, Spiess J, Rogers SW: Glutamate receptor antibodies activate a subset of receptors and reveal an agonist binding site. Neuron 1995; 14: 755-762.
22. Werner P, Pitt D, Raine CS: Multiple sclerosis: altered glutamate homeostasis in lesions correlates with oligodendrocyte and axonal damage. Ann Neurol 2001; 50: 169-180. (Pubitemid 32738141)
23. Camdessache J-P, Streichenberger N, Cavillon G, Rogemond V, Jousserand G, Honnorat J, Covers P, Antoine J-C: Brain immunohistopathological study in a patient with anti-NMDAR encephalitis. Eur J Neurol 2011; 18: 929-931.
24. Groom AJ, Smith T, Turski L: Multiple sclerosis and glutamate. Ann NY Acad Sci 2003; 993: 229-275. (Pubitemid 36808454)
25. Sarchielli P, Greco L, Floridi A, Gallai V: Excitatory amino acids and multiple sclerosis: evidence from cerebrospinal fluid. Arch Neurol 2003; 60: 1082-1088. (Pubitemid 36975795)
26. Pitt D, Werner P, Raine C: Glutamate excitotoxicity in a model of multiple sclerosis. Nat Med 2006; 6: 67-70.
27. Hohlfeld R, Wekerle H: Autoimmune concepts of multiple sclerosis as a basis for selective immunotherapy. Proc Natl Acad Sci USA 2004; 101: 14599-14606.
28. Haase CG, Guggenmos J, Brehm U, Andersson M, Olsson T, Reindl M, Schneidewind JM, Zettl UK, Heidenreich F, Berger T, Wekerle H, Hohlfeld R, Linington C: The fine specificity of the myelin oligodendrocyte glycoprotein autoantibody response in patients with multiple sclerosis and normal healthy controls. J Neuroimmun 2001; 114: 220-225. (Pubitemid 32184745)
29. Burnashev N: Calcium permeability of glutamate-gated channels in the central nervous system. Curr Opin Neurobiol 1996; 6: 311-317. (Pubitemid 26235678)
30. Cohen-Kashi Malina K, Ganor Y, Levite M, Teichberg VI: Autoantibodies against an extracellular peptide of the GluR3 subtype of AMPA receptors activate both homomeric and heteromeric AMPA receptor channels. Neurochem Res 2006; 31: 1181-1190. (Pubitemid 44701764)
31. Evan GI, Lewis GK, Ramsay G, Bishop JM: Isolation of monoclonal antibodies specific for human c-myc proto-oncogene product. Mol Cell Biol 1985; 5: 3610-3616. (Pubitemid 16233068)
32. Rosenberg AS: Effects of protein aggregates: an immunologic perspective. AAPS J 2006; 8:E501-E507. (Pubitemid 44294011)
33. Yamashita S, Okuda Y: Mechanisms of heatinduced antigen retrieval. J Histochem Cytochem 2005; 53: 13-21.