Novel nanostructured lipid carrier co-loaded with doxorubicin and docosahexaenoic acid demonstrates enhanced in vitro activity and overcomes drug resistance in MCF-7/Adr cells

Pharmaceutical Research

Volumn 31, Issue 8, 2014, Pages 1882-1892

  Mussi, Samuel V ^a,b   Sawant, Rupa ^b   Perche, Federico ^b   Oliveira, Mônica C ^a   Azevedo, Ricardo B ^c   Ferreira, Lucas A M ^a   Torchilin, Vladimir P ^b  

^a FEDERAL UNIVERSITY OF MINAS GERAIS   (Brazil)

^b NORTHEASTERN UNIVERSITY   (United States)

^c UNIVERSITY OF BRASILIA   (Brazil)

Author keywords

cancer therapy; docosahexaenoic acid; doxorubicin; nanostructured lipid carrier; resistance overcoming

Indexed keywords

DOCOSAHEXAENOIC ACID; DOXORUBICIN; DRUG CARRIER; NANOMATERIAL;

CELL SURVIVAL; CHEMISTRY; DOSE RESPONSE; DRUG EFFECTS; DRUG RESISTANCE; HUMAN; MCF 7 CELL LINE; MEDICINAL CHEMISTRY; MULTIDRUG RESISTANCE; PHYSIOLOGY;

CELL SURVIVAL; CHEMISTRY, PHARMACEUTICAL; DOCOSAHEXAENOIC ACIDS; DOSE-RESPONSE RELATIONSHIP, DRUG; DOXORUBICIN; DRUG CARRIERS; DRUG RESISTANCE, MULTIPLE; DRUG RESISTANCE, NEOPLASM; HUMANS; MCF-7 CELLS; NANOSTRUCTURES;

EID: 84893660534     PISSN: 07248741     EISSN: 1573904X     Source Type: Journal    
DOI: 10.1007/s11095-013-1290-2     Document Type: Article

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