CDK inhibitors, p21Cip1 and p27Kip1, participate in cell cycle exit of mammalian cardiomyocytes

Biochemical and Biophysical Research Communications

Volumn 443, Issue 3, 2014, Pages 1105-1109

  Tane, Shoji ^a   Ikenishi, Aiko ^a   Okayama, Hitomi ^a   Iwamoto, Noriko ^a,c   Nakayama, Keiichi I ^b   Takeuchi, Takashi ^a  

^a TOTTORI UNIVERSITY   (Japan)

^b KYUSHU UNIVERSITY   (Japan)

^c Kinutani Women's Clinic   (Japan)

Author keywords

Cardiomyocyte; CDK inhibitor; Cell cycle exit; Mouse

Indexed keywords

CYCLIN A; CYCLIN DEPENDENT KINASE 2; CYCLIN DEPENDENT KINASE INHIBITOR 1; CYCLIN DEPENDENT KINASE INHIBITOR 1B; CYCLIN E;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CELL CYCLE; CELL CYCLE G1 PHASE; COMPLEX FORMATION; CONTROLLED STUDY; ENZYME ACTIVITY; HEART MUSCLE CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION;

MAMMALIA; MUS;

CARDIOMYOCYTE; CDK; CDK INHIBITOR; CELL CYCLE EXIT; CKI; CM; CYCLIN DEPENDENT KINASE; CYCLIN DEPENDENT KINASE INHIBITOR; KNOCKOUT; KO; MOUSE;

ANIMALS; CELL CYCLE; CYCLIN-DEPENDENT KINASE INHIBITOR P21; CYCLIN-DEPENDENT KINASE INHIBITOR P27; GENE EXPRESSION REGULATION; MAMMALS; MICE; MICE, INBRED C57BL; MYOCYTES, CARDIAC;

EID: 84893651561     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2013.12.109     Document Type: Article

References (19)

1. I.L. Erokhina Proliferation dynamics of cellular elements in the differentiating mouse myocardium Tsitologia 10 1968 1391 1409
2. M. Toyoda, H. Shirato, K. Nakajima, M. Kojima, M. Takahashi, M. Kubota, R. Suzuki-Migishima, Y. Motegi, M. Yokoyama, and T. Takeuchi Jumonji downregulates cardiac cell proliferation by repressing cyclin D1 expression Dev. Cell 5 2003 85 97
3. M.H. Soonpaa, K.K. Kim, L. Pajak, M. Franklin, and L.J. Field Cardiomyocyte DNA synthesis and binucleation during murine development Am. J. Physiol. 271 1996 H2183 H2189
4. A. Ikenishi, H. Okayama, N. Iwamoto, S. Yoshitome, S. Tane, K. Nakamura, T. Obayashi, T. Hayashi, and T. Takeuchi Cell cycle regulation in mouse heart during embryonic and postnatal stages Dev. Growth Differ. 54 2012 731 738
5. M. Mollova, K. Bersell, S. Walsh, J. Savla, L.T. Das, S.-Y. Park, L.E. Silberstein, C.G. dos Remedios, D. Graham, S. Colan, and B. Kuhn Cardiomyocyte proliferation contributes to heart growth in young humans Proc. Natl. Acad. Sci. 110 2013 1446 1451
6. S.E. Senyo, M.L. Steinhauser, C.L. Pizzimenti, V.K. Yang, L. Cai, M. Wang, T.-D. Wu, J.-L. Guerquin-Kern, C.P. Lechene, and R.T. Lee Mammalian heart renewal by pre-existing cardiomyocytes Nature 493 2013 433 436
7. C.J. Sherr, and J.M. Roberts CDK inhibitors: positive and negative regulators of G1-phase progression Genes Dev. 13 1999 1501 1512
8. C. Deng, P. Zhang, J. Wade Harper, S.J. Elledge, and P. Leder Mice lacking p21Cip1/Waf1 undergo normal development, but are defective in G1 checkpoint control Cell 82 1995 675 684
9. J. Brugarolas, C. Chandrasekaran, J.I. Gordon, D. Beach, T. Jacks, and G.J. Hannon Radiation-induced cell cycle arrest compromised by p21 deficiency Nature 377 1995 552 557
10. H. Kiyokawa, R.D. Kineman, K.O. Manova-Todorova, V.C. Soares, E.S. Hoffman, M. Ono, D. Khanam, A.C. Hayday, L.A. Frohman, and A. Koff Enhanced growth of mice lacking the cyclin-dependent kinase inhibitor function of p27Kip1 Cell 85 1996 721 732
11. K. Nakayama, N. Ishida, M. Shirane, A. Inomata, T. Inoue, N. Shishido, I. Horii, D.Y. Loh, and K.-I. Nakayama Mice lacking p27Kip1 display increased body size, multiple organ hyperplasia, retinal dysplasia, and pituitary tumors Cell 85 1996 707 720
12. Y. Yan, J. Frisen, M.H. Lee, J. Massague, and M. Barbacid Ablation of the CDK inhibitor p57Kip2 results in increased apoptosis and delayed differentiation during mouse development Genes Dev. 11 1997 973 983
13. K. Takahashi, K.-I. Nakayama, and K. Nakayama Mice lacking a CDK inhibitor, p57Kip2, exhibit skeletal abnormalities and growth retardation J. Biochem. 127 2000 73 83
14. T. Shioya A simple technique for isolating healthy heart cells from mouse models J. Physiol. Sci. 57 2007 327 335
15. K. Nakajima, M. Inagawa, C. Uchida, K. Okada, S. Tane, M. Kojima, M. Kubota, M. Noda, S. Ogawa, H. Shirato, M. Sato, R. Suzuki-Migishima, T. Hino, Y. Satoh, M. Kitagawa, and T. Takeuchi Coordinated regulation of differentiation and proliferation of embryonic cardiomyocytes by a jumonji (jarid2)-cyclin D1 pathway Development 138 2011 1771 1782
16. H. Shirato, S. Ogawa, K. Nakajima, M. Inagawa, M. Kojima, M. Tachibana, Y. Shinkai, and T. Takeuchi A jumonji (jarid2) protein complex represses cyclin D1 expression by methylation of histone H3-K9 J. Biol. Chem. 284 2009 733 739
17. J.W. Harper, S.J. Elledge, K. Keyomarsi, B. Dynlacht, L.H. Tsai, P. Zhang, S. Dobrowolski, C. Bai, L. Connell-Crowley, and E. Swindell Inhibition of cyclin-dependent kinases by p21 Mol. Biol. Cell 6 1995 387 400
18. R.A. Garcia-Fernandez, P. Garcia-Palencia, M.A. Sanchez, G. Gil-Gomez, B. Sanchez, E. Rollan, J. Martin-Caballero, and J.M. Flores Combined loss of p21Waf1/Cip1 and p27Kip1 enhances tumorigenesis in mice Lab. Invest. 91 2011 1634 1642
19. A.I. Mahmoud, F. Kocabas, S.A. Muralidhar, W. Kimura, A.S. Koura, S. Thet, E.R. Porrello, and H.A. Sadek Meis1 regulates postnatal cardiomyocyte cell cycle arrest Nature 497 2013 249 253