-
1
-
-
36849074168
-
Prasugrel: A novel thienopyridine antiplatelet agent. A review of preclinical and clinical studies and the mechanistic basis for its distinct antiplatelet profile
-
DOI 10.1111/j.1527-3466.2007.00027.x
-
J.A. Jakubowski, K.J. Winters, H. Naganuma, and L. Wallentin Prasugrel: a novel thienopyridine antiplatelet agent A review of preclinical and clinical studies and the mechanistic basis for its distinct antiplatelet profile Cardiovasc Drug Rev 25 2007 357 374 (Pubitemid 350233359)
-
(2007)
Cardiovascular Drug Reviews
, vol.25
, Issue.4
, pp. 357-374
-
-
Jakubowski, J.A.1
Winters, K.J.2
Naganuma, H.3
Wallentin, L.4
-
2
-
-
37349111065
-
Prasugrel compared with high loading- and maintenance-dose clopidogrel in patients with planned percutaneous coronary intervention: The prasugrel in comparison to clopidogrel for inhibition of platelet activation and aggregation-thrombolysis in myocardial infarction 44 trial
-
DOI 10.1161/CIRCULATIONAHA.107.740324
-
S.D. Wiviott, D. Trenk, A.L. Frelinger, M. O'Donoghue, F.J. Neumann, A.D. Michelson, D.J. Angiolillo, H. Hod, G. Montalescot, D.L. Miller, J.A. Jakubowski, R. Cairns, S.A. Murphy, C.H. McCabe, E.M. Antman, E. Braunwald PRINCIPLE-TIMI 44 Investigators Prasugrel compared with high loading- and maintenance-dose clopidogrel in patients with planned percutaneous coronary intervention: the Prasugrel in Comparison to Clopidogrel for Inhibition of Platelet Activation and AggregationThrombolysis In Myocardial Infarction 44 trial Circulation 116 2007 2923 2932 (Pubitemid 350291199)
-
(2007)
Circulation
, vol.116
, Issue.25
, pp. 2923-2932
-
-
Wiviott, S.D.1
Trenk, D.2
Frelinger, A.L.3
O'Donoghue, M.4
Neumann, F.-J.5
Michelson, A.D.6
Angiolillo, D.J.7
Hod, H.8
Montalescot, G.9
Miller, D.L.10
Jakubowski, J.A.11
Cairns, R.12
Murphy, S.A.13
McCabe, C.H.14
Antman, E.M.15
Braunwald, E.16
-
3
-
-
36148983750
-
Prasugrel versus clopidogrel in patients with acute coronary syndromes
-
DOI 10.1056/NEJMoa0706482
-
S.D. Wiviott, E. Braunwald, C.H. McCabe, G. Montalescot, W. Ruzyllo, S. Gottlieb, F.J. Neumann, D. Ardissino, S. De Servi, S.A. Murphy, J. Riesmeyer, G. Weerakkody, C.M. Gibson, and E.M. Antman Prasugrel versus Clopidogrel in Patients with Acute Coronary Syndromes N Engl J Med 357 2007 2001 2015 (Pubitemid 350106708)
-
(2007)
New England Journal of Medicine
, vol.357
, Issue.20
, pp. 2001-2015
-
-
Wiviott, S.D.1
Braunwald, E.2
McCabe, C.H.3
Montalescot, G.4
Ruzyllo, W.5
Gottlieb, S.6
Neumann, F.-J.7
Ardissino, D.8
De Servi, S.9
Murphy, S.A.10
Riesmeyer, J.11
Weerakkody, G.12
Gibson, C.M.13
Antman, E.M.14
-
4
-
-
69949163560
-
Weighing benefits and risksthe FDA's review of prasugrel
-
E.F. Unger Weighing benefits and risksthe FDA's review of prasugrel N Engl J Med 361 2009 942 945
-
(2009)
N Engl J Med
, vol.361
, pp. 942-945
-
-
Unger, E.F.1
-
5
-
-
72449133295
-
-
United States Food and Drug Administration Accessed on May 9, 2011
-
United States Food and Drug Administration FDA approved drug products http://www.accessdata.fda.gov/scripts/cder/drugsatfda/index.cfm?fuseaction= Search.DrugDetails 2009 Accessed on May 9, 2011
-
(2009)
FDA Approved Drug Products
-
-
-
6
-
-
70349266838
-
Population pharmacokinetic analyses to evaluate the influence of intrinsic and extrinsic factors on exposure of prasugrel active metabolite in TRITON-TIMI 38
-
R.E. Wrishko, C.S. Ernest, D.S. Small, Y.G. Li, G.J. Weerakkody, J.R. Riesmeyer, W.L. Macias, S. Rohatagi, D.E. Salazar, E.M. Antman, S.D. Wiviott, E. Braunwald, and L. Ni Population pharmacokinetic analyses to evaluate the influence of intrinsic and extrinsic factors on exposure of prasugrel active metabolite in TRITON-TIMI 38 J Clin Pharmacol 49 2009 984 998
-
(2009)
J Clin Pharmacol
, vol.49
, pp. 984-998
-
-
Wrishko, R.E.1
Ernest, C.S.2
Small, D.S.3
Li, Y.G.4
Weerakkody, G.J.5
Riesmeyer, J.R.6
MacIas, W.L.7
Rohatagi, S.8
Salazar, D.E.9
Antman, E.M.10
Wiviott, S.D.11
Braunwald, E.12
Ni, L.13
-
8
-
-
33748680917
-
Evaluation of prasugrel compared with clopidogrel in patients with acute coronary syndromes: Design and rationale for the TRial to assess Improvement in Therapeutic Outcomes by optimizing platelet InhibitioN with prasugrel Thrombolysis In Myocardial Infarction 38 (TRITON-TIMI 38)
-
DOI 10.1016/j.ahj.2006.04.012, PII S0002870306003486
-
S.D. Wiviott, E.M. Antman, C.M. Gibson, G. Montalescot, J. Riesmeyer, G. Weerakkody, K.J. Winters, J.W. Warmke, C.H. McCabe, E. Braunwald TRITON-TIMI 38 Investigators Evaluation of prasugrel compared with clopidogrel in patients with acute coronary syndromes: design and rationale for the TRial to assess Improvement in Therapeutic Outcomes by optimizing platelet InhibitioN with prasugrel Thrombolysis In Myocardial Infarction 38 (TRITON-TIMI 38) Am Heart J 152 2006 627 635 (Pubitemid 44396884)
-
(2006)
American Heart Journal
, vol.152
, Issue.4
, pp. 627-635
-
-
Wiviott, S.D.1
Antman, E.M.2
Gibson, C.M.3
Montalescot, G.4
Riesmeyer, J.5
Weerakkody, G.6
Winters, K.J.7
Warmke, J.W.8
McCabe, C.H.9
Braunwald, E.10
-
9
-
-
80052730648
-
Lack of benefit and evidence for harm with prasugrel as compared to clopidogrel in patients with a history of TIA/CVA undergoing PCI: Insights from TRITON-TIMI 38
-
N. Desai, E. Antman, and S. Murphy Lack of benefit and evidence for harm with prasugrel as compared to clopidogrel in patients with a history of TIA/CVA undergoing PCI: insights from TRITON-TIMI 38 ACC scientific sessions abstract 2009
-
(2009)
ACC Scientific Sessions Abstract
-
-
Desai, N.1
Antman, E.2
Murphy, S.3
-
10
-
-
3242770664
-
Aspirin and clopidogrel compared with clopidogrel alone after recent ischaemic stroke or transient ischaemic attack in high-risk patients (MATCH): Randomised, double-blind, placebo-controlled trial
-
MATCH Investigators
-
H.C. Diener, J. Bogousslavsky, L.M. Brass, C. Cimminiello, L. Csiba, M. Kaste, D. Leys, J. Matias-Guiu, H.J. Rupprecht MATCH Investigators Aspirin and clopidogrel compared with clopidogrel alone after recent ischaemic stroke or transient ischaemic attack in high-risk patients (MATCH): randomised, double-blind, placebo-controlled trial Lancet 364 2004 331 337
-
(2004)
Lancet
, vol.364
, pp. 331-337
-
-
Diener, H.C.1
Bogousslavsky, J.2
Brass, L.M.3
Cimminiello, C.4
Csiba, L.5
Kaste, M.6
Leys, D.7
Matias-Guiu, J.8
Rupprecht, H.J.9
-
11
-
-
51449116270
-
Aspirin and extended-release dipyridamole versus clopidogrel for recurrent stroke
-
PRoFESS Study Group
-
R.L. Sacco, H.C. Diener, S. Yusuf, D. Cotton, S. Ounpuu, W.A. Lawton, Y. Palesch, R.H. Martin, G.W. Albers, P. Bath, N. Bornstein, B.P. Chan, S.T. Chen, L. Cunha, B. Dahlöf, J. De Keyser, G.A. Donnan, C. Estol, P. Gorelick, V. Gu, K. Hermansson, L. Hilbrich, M. Kaste, C. Lu, T. Machnig, P. Pais, R. Roberts, V. Skvortsova, P. Teal, D. Toni, C. Vandermaelen, T. Voigt, M. Weber, B.W. Yoon PRoFESS Study Group Aspirin and extended-release dipyridamole versus clopidogrel for recurrent stroke N Engl J Med 359 2008 1238 1251
-
(2008)
N Engl J Med
, vol.359
, pp. 1238-1251
-
-
Sacco, R.L.1
Diener, H.C.2
Yusuf, S.3
Cotton, D.4
Ounpuu, S.5
Lawton, W.A.6
Palesch, Y.7
Martin, R.H.8
Albers, G.W.9
Bath, P.10
Bornstein, N.11
Chan, B.P.12
Chen, S.T.13
Cunha, L.14
Dahlöf, B.15
De Keyser, J.16
Donnan, G.A.17
Estol, C.18
Gorelick, P.19
Gu, V.20
Hermansson, K.21
Hilbrich, L.22
Kaste, M.23
Lu, C.24
MacHnig, T.25
Pais, P.26
Roberts, R.27
Skvortsova, V.28
Teal, P.29
Toni, D.30
Vandermaelen, C.31
Voigt, T.32
Weber, M.33
Yoon, B.W.34
more..
-
12
-
-
42149119040
-
Intensive oral antiplatelet therapy for reduction of ischaemic events including stent thrombosis in patients with acute coronary syndromes treated with percutaneous coronary intervention and stenting in the TRITON-TIMI 38 trial: A subanalysis of a randomised trial
-
TRITON-TIMI 38 Investigators
-
S.D. Wiviott, E. Braunwald, C.H. McCabe, I. Horvath, M. Keltai, J.P. Herrman, F. Van de Werf, W.E. Downey, B.M. Scirica, S.A. Murphy, E.M. Antman TRITON-TIMI 38 Investigators Intensive oral antiplatelet therapy for reduction of ischaemic events including stent thrombosis in patients with acute coronary syndromes treated with percutaneous coronary intervention and stenting in the TRITON-TIMI 38 trial: a subanalysis of a randomised trial Lancet 371 2008 1353 1363
-
(2008)
Lancet
, vol.371
, pp. 1353-1363
-
-
Wiviott, S.D.1
Braunwald, E.2
McCabe, C.H.3
Horvath, I.4
Keltai, M.5
Herrman, J.P.6
Van De Werf, F.7
Downey, W.E.8
Scirica, B.M.9
Murphy, S.A.10
Antman, E.M.11
-
13
-
-
33845319222
-
Late Clinical Events After Clopidogrel Discontinuation May Limit the Benefit of Drug-Eluting Stents. An Observational Study of Drug-Eluting Versus Bare-Metal Stents
-
DOI 10.1016/j.jacc.2006.10.026, PII S073510970602523X
-
M. Pfisterer, H.P. Brunner-La Rocca, P.T. Buser, P. Rickenbacher, P. Hunziker, C. Mueller, R. Jeger, F. Bader, S. Osswald, C. Kaiser BASKET-LATE Investigators Late clinical events after clopidogrel discontinuation may limit the benefit of drug-eluting stents: an observational study of drug-eluting versus bare-metal stents J Am Coll Cardiol 48 2006 2584 2591 (Pubitemid 44881238)
-
(2006)
Journal of the American College of Cardiology
, vol.48
, Issue.12
, pp. 2584-2591
-
-
Pfisterer, M.1
Brunner-La Rocca, H.P.2
Buser, P.T.3
Rickenbacher, P.4
Hunziker, P.5
Mueller, C.6
Jeger, R.7
Bader, F.8
Osswald, S.9
Kaiser, C.10
-
14
-
-
33847167065
-
Early and late coronary stent thrombosis of sirolimus-eluting and paclitaxel-eluting stents in routine clinical practice: Data from a large two-institutional cohort study
-
DOI 10.1016/S0140-6736(07)60314-6, PII S0140673607603146
-
J. Daemen, P. Wenaweser, K. Tsuchida, L. Abrecht, S. Vaina, C. Morger, N. Kukreja, P. Jni, G. Sianos, G. Hellige, R.T. van Domburg, O.M. Hess, E. Boersma, B. Meier, S. Windecker, and P.W. Serruys Early and late coronary stent thrombosis of sirolimus-eluting and paclitaxel-eluting stents in routine clinical practice: data from a large two-institutional cohort study Lancet 369 2007 667 678 (Pubitemid 46281313)
-
(2007)
Lancet
, vol.369
, Issue.9562
, pp. 667-678
-
-
Daemen, J.1
Wenaweser, P.2
Tsuchida, K.3
Abrecht, L.4
Vaina, S.5
Morger, C.6
Kukreja, N.7
Juni, P.8
Sianos, G.9
Hellige, G.10
Van Domburg, R.T.11
Hess, O.M.12
Boersma, E.13
Meier, B.14
Windecker, S.15
Serruys, P.W.16
-
15
-
-
20344408497
-
Stent thrombosis is associated with an impaired response to antiplatelet therapy
-
DOI 10.1016/j.jacc.2005.01.058, PII S0735109705006352
-
P. Wenaweser, J. Dörffler-Melly, K. Imboden, S. Windecker, M. Togni, B. Meier, A. Haeberli, and O.M. Hess Stent thrombosis is associated with an impaired response to antiplatelet therapy J Am Coll Cardiol 45 2005 1748 1752 (Pubitemid 40779850)
-
(2005)
Journal of the American College of Cardiology
, vol.45
, Issue.11
, pp. 1748-1752
-
-
Wenaweser, P.1
Dorffler-Melly, J.2
Imboden, K.3
Windecker, S.4
Togni, M.5
Meier, B.6
Haeberli, A.7
Hess, O.M.8
-
16
-
-
34250020766
-
Impact of Platelet Reactivity After Clopidogrel Administration on Drug-Eluting Stent Thrombosis
-
DOI 10.1016/j.jacc.2007.01.094, PII S0735109707011345
-
P. Buonamici, R. Marcucci, A. Migliorini, G.F. Gensini, A. Santini, R. Paniccia, G. Moschi, A.M. Gori, R. Abbate, and D. Antoniucci Impact of platelet reactivity after clopidogrel administration on drug-eluting stent thrombosis J Am Coll Cardiol 49 2007 2312 2317 (Pubitemid 46891710)
-
(2007)
Journal of the American College of Cardiology
, vol.49
, Issue.24
, pp. 2312-2317
-
-
Buonamici, P.1
Marcucci, R.2
Migliorini, A.3
Gensini, G.F.4
Santini, A.5
Paniccia, R.6
Moschi, G.7
Gori, A.M.8
Abbate, R.9
Antoniucci, D.10
-
17
-
-
65249145201
-
Cytochrome P450 2C19 loss-of-function polymorphism and stent thrombosis following percutaneous coronary intervention
-
D. Sibbing, J. Stegherr, W. Latz, W. Koch, J. Mehilli, K. Dörrler, T. Morath, A. Schömig, A. Kastrati, and N. von Beckerath Cytochrome P450 2C19 loss-of-function polymorphism and stent thrombosis following percutaneous coronary intervention Eur Heart J 30 2009 916 922
-
(2009)
Eur Heart J
, vol.30
, pp. 916-922
-
-
Sibbing, D.1
Stegherr, J.2
Latz, W.3
Koch, W.4
Mehilli, J.5
Dörrler, K.6
Morath, T.7
Schömig, A.8
Kastrati, A.9
Von Beckerath, N.10
-
18
-
-
58249135635
-
Cytochrome P450 2C19 polymorphism in young patients treated with clopidogrel after myocardial infarction: A cohort study
-
J.P. Collet, J.S. Hulot, A. Pena, E. Villard, J.B. Esteve, J. Silvain, L. Payot, D. Brugier, G. Cayla, F. Beygui, G. Bensimon, C. Funck-Brentano, and G. Montalescot Cytochrome P450 2C19 polymorphism in young patients treated with clopidogrel after myocardial infarction: a cohort study Lancet 373 2009 309 317
-
(2009)
Lancet
, vol.373
, pp. 309-317
-
-
Collet, J.P.1
Hulot, J.S.2
Pena, A.3
Villard, E.4
Esteve, J.B.5
Silvain, J.6
Payot, L.7
Brugier, D.8
Cayla, G.9
Beygui, F.10
Bensimon, G.11
Funck-Brentano, C.12
Montalescot, G.13
-
19
-
-
58749094444
-
Cytochrome p-450 polymorphisms and response to clopidogrel
-
J.L. Mega, S.L. Close, S.D. Wiviott, L. Shen, R.D. Hockett, J.T. Brandt, J.R. Walker, E.M. Antman, W. Macias, E. Braunwald, and M.S. Sabatine Cytochrome p-450 polymorphisms and response to clopidogrel N Engl J Med 360 2009 354 362
-
(2009)
N Engl J Med
, vol.360
, pp. 354-362
-
-
Mega, J.L.1
Close, S.L.2
Wiviott, S.D.3
Shen, L.4
Hockett, R.D.5
Brandt, J.T.6
Walker, J.R.7
Antman, E.M.8
MacIas, W.9
Braunwald, E.10
Sabatine, M.S.11
|