-
1
-
-
84856223248
-
Aldehyde dehydrogenases and cell proliferation
-
10.1016/j.freeradbiomed.2011.11.033 1:CAS:528:DC%2BC38XhsF2qsr4%3D 22206977 10.1016/j.freeradbiomed.2011.11.033
-
Muzio G, Maggiora M, Paiuzzi E et al (2012) Aldehyde dehydrogenases and cell proliferation. Free Radic Biol Med 52:735-746. doi: 10.1016/j. freeradbiomed.2011.11.033
-
(2012)
Free Radic Biol Med
, vol.52
, pp. 735-746
-
-
Muzio, G.1
Maggiora, M.2
Paiuzzi, E.3
-
2
-
-
84873465688
-
Ocular aldehyde dehydrogenases: Rotection against ultraviolet damage and maintenance of transparency for vision
-
10.1016/j.preteyeres.2012.10.001 23098688 10.1016/j.preteyeres.2012.10. 001
-
Chen Y, Thompson DC, Koppaka V et al (2012) Ocular aldehyde dehydrogenases: rotection against ultraviolet damage and maintenance of transparency for vision. Prog Retin Eye Res 33:28-39. doi: 10.1016/j.preteyeres. 2012.10.001
-
(2012)
Prog Retin Eye Res
, vol.33
, pp. 28-39
-
-
Chen, Y.1
Thompson, D.C.2
Koppaka, V.3
-
3
-
-
84862736649
-
Retinaldehyde dehydrogenase 1 coordinates hepatic gluconeogenesis and lipid metabolism
-
10.1210/en.2011-2104 1:CAS:528:DC%2BC38XpsFWgtbs%3D 22555438 10.1210/en.2011-2104
-
Kiefer FW, Orasanu G, Nallamshetty S et al (2012) Retinaldehyde dehydrogenase 1 coordinates hepatic gluconeogenesis and lipid metabolism. Endocrinology 153:3089-3099. doi: 10.1210/en.2011-2104
-
(2012)
Endocrinology
, vol.153
, pp. 3089-3099
-
-
Kiefer, F.W.1
Orasanu, G.2
Nallamshetty, S.3
-
4
-
-
74949129868
-
Aldehyde dehydrogenase 1-positive cancer stem cells mediate metastasis and poor clinical outcome in inflammatory breast cancer
-
10.1158/1078-0432.CCR-09-1630 1:CAS:528:DC%2BC3cXot1Wh 2874875 20028757 10.1158/1078-0432.CCR-09-1630
-
Charafe-Jauffret E, Ginestier C, Iovino F et al (2010) Aldehyde dehydrogenase 1-positive cancer stem cells mediate metastasis and poor clinical outcome in inflammatory breast cancer. Clin Cancer Res 16:45-55. doi: 10.1158/1078-0432.CCR-09-1630
-
(2010)
Clin Cancer Res
, vol.16
, pp. 45-55
-
-
Charafe-Jauffret, E.1
Ginestier, C.2
Iovino, F.3
-
5
-
-
84863822668
-
Aldehyde dehydrogenase 1A1 possesses stem-like properties and predicts lung cancer patient outcome
-
10.1097/JTO.0b013e318257cc6d 22617249 10.1097/JTO.0b013e318257cc6d
-
Li X, Wan L, Geng J et al (2012) Aldehyde dehydrogenase 1A1 possesses stem-like properties and predicts lung cancer patient outcome. J Thorac Oncol 7:1235-1245. doi: 10.1097/JTO.0b013e318257cc6d
-
(2012)
J Thorac Oncol
, vol.7
, pp. 1235-1245
-
-
Li, X.1
Wan, L.2
Geng, J.3
-
6
-
-
84866671365
-
ALDH1A isozymes are markers of human melanoma stem cells and potential therapeutic targets
-
10.1002/stem.1193 1:CAS:528:DC%2BC38XhsF2ntrfK 3448863 22887839 10.1002/stem.1193
-
Luo Y, Dallaglio K, Chen Y et al (2012) ALDH1A isozymes are markers of human melanoma stem cells and potential therapeutic targets. Stem Cells 30:2100-2113. doi: 10.1002/stem.1193
-
(2012)
Stem Cells
, vol.30
, pp. 2100-2113
-
-
Luo, Y.1
Dallaglio, K.2
Chen, Y.3
-
7
-
-
52549087785
-
Cancer stem cells in solid tumours: Accumulating evidence and unresolved questions
-
1:CAS:528:DC%2BD1cXhtFCrtb3K 18784658 10.1038/nrc2499
-
Visvader JE, Lindeman GJ (2008) Cancer stem cells in solid tumours: accumulating evidence and unresolved questions. Nat Rev Cancer 8:755-768
-
(2008)
Nat Rev Cancer
, vol.8
, pp. 755-768
-
-
Visvader, J.E.1
Lindeman, G.J.2
-
8
-
-
58049221188
-
ALDH isozymes downregulation affects cell growth, cell motility and gene expression in lung cancer cells
-
10.1186/1476-4598-7-87 2605459 19025616 10.1186/1476-4598-7-87
-
Moreb JS, Baker HV, Chang L-J et al (2008) ALDH isozymes downregulation affects cell growth, cell motility and gene expression in lung cancer cells. Mol Cancer 7:87. doi: 10.1186/1476-4598-7-87
-
(2008)
Mol Cancer
, vol.7
, pp. 87
-
-
Moreb, J.S.1
Baker, H.V.2
Chang, L.-J.3
-
9
-
-
33747429806
-
Arachidonic acid suppresses growth of human lung tumor A549 cells through down-regulation of ALDH3A1 expression
-
10.1016/j.freeradbiomed.2006.01.020 1:CAS:528:DC%2BD28XkvVyjurg%3D 16716894 10.1016/j.freeradbiomed.2006.01.020
-
Muzio G, Trombetta A, Maggiora M et al (2006) Arachidonic acid suppresses growth of human lung tumor A549 cells through down-regulation of ALDH3A1 expression. Free Radic Biol Med 40:1929-1938. doi: 10.1016/j.freeradbiomed.2006. 01.020
-
(2006)
Free Radic Biol Med
, vol.40
, pp. 1929-1938
-
-
Muzio, G.1
Trombetta, A.2
Maggiora, M.3
-
10
-
-
0035969830
-
Inhibition of cytosolic class 3 aldehyde dehydrogenase by antisense oligonucleotides in rat hepatoma cells
-
11306046 10.1016/S0009-2797(00)00281-7
-
Muzio G, Canuto RA, Trombetta A, Maggiora M (2001) Inhibition of cytosolic class 3 aldehyde dehydrogenase by antisense oligonucleotides in rat hepatoma cells. Chem Biol Interact 130-132:219-225
-
(2001)
Chem Biol Interact
, vol.130-132
, pp. 219-225
-
-
Muzio, G.1
Canuto, R.A.2
Trombetta, A.3
Maggiora, M.4
-
11
-
-
84865004801
-
Aldehyde dehydrogenase 1A1 confers intrinsic and acquired resistance to gemcitabine in human pancreatic adenocarcinoma MIA PaCa-2 cells
-
10.3892/ijo.2012.1516 1:CAS:528:DC%2BC38XhtlWhurnE 22710732
-
Duong H-Q, Hwang JS, Kim HJ et al (2012) Aldehyde dehydrogenase 1A1 confers intrinsic and acquired resistance to gemcitabine in human pancreatic adenocarcinoma MIA PaCa-2 cells. Int J Oncol 41:855-861. doi: 10.3892/ijo.2012.1516
-
(2012)
Int J Oncol
, vol.41
, pp. 855-861
-
-
Duong, H.-Q.1
Hwang, J.S.2
Kim, H.J.3
-
12
-
-
84868496506
-
ALDH-positive lung cancer stem cells confer resistance to epidermal growth factor receptor tyrosine kinase inhibitors
-
10.1016/j.canlet.2012.08.021 1:CAS:528:DC%2BC38Xhtl2rsrnF 22935675 10.1016/j.canlet.2012.08.021
-
Huang C-P, Tsai M-F, Chang T-H et al (2013) ALDH-positive lung cancer stem cells confer resistance to epidermal growth factor receptor tyrosine kinase inhibitors. Cancer Lett 328:144-151. doi: 10.1016/j.canlet.2012.08.021
-
(2013)
Cancer Lett
, vol.328
, pp. 144-151
-
-
Huang, C.-P.1
Tsai, M.-F.2
Chang, T.-H.3
-
13
-
-
84857792056
-
Aldehyde dehydrogenase 1A1 expression in breast cancer is associated with stage, triple negativity, and outcome to neoadjuvant chemotherapy
-
10.1038/modpathol.2011.172 1:CAS:528:DC%2BC38Xjt1Wqtb0%3D 3426278 22080062 10.1038/modpathol.2011.172
-
Khoury T, Ademuyiwa FO, Chandrasekhar R et al (2012) Aldehyde dehydrogenase 1A1 expression in breast cancer is associated with stage, triple negativity, and outcome to neoadjuvant chemotherapy. Mod Pathol 25:388-397. doi: 10.1038/modpathol.2011.172
-
(2012)
Mod Pathol
, vol.25
, pp. 388-397
-
-
Khoury, T.1
Ademuyiwa, F.O.2
Chandrasekhar, R.3
-
14
-
-
84869177666
-
Aldehyde dehydrogenase 1A1-A new mediator of resistance to temozolomide in glioblastoma
-
10.1093/neuonc/nos270 3499020 23132408 10.1093/neuonc/nos270
-
Schäfer A, Teufel J, Ringel F et al (2012) Aldehyde dehydrogenase 1A1-a new mediator of resistance to temozolomide in glioblastoma. Neuro-oncology 14:1452-1464. doi: 10.1093/neuonc/nos270
-
(2012)
Neuro-oncology
, vol.14
, pp. 1452-1464
-
-
Schäfer, A.1
Teufel, J.2
Ringel, F.3
-
15
-
-
0028672634
-
Immunohistochemical study of hepatocellular carcinoma-specific aldehyde dehydrogenase
-
1:CAS:528:DyaK2MXotFKgtbc%3D 9063810
-
Shibuya A, Takeuchi A, Shibata H et al (1994) Immunohistochemical study of hepatocellular carcinoma-specific aldehyde dehydrogenase. Alcohol Alcohol Suppl 29:119-123
-
(1994)
Alcohol Alcohol Suppl
, vol.29
, pp. 119-123
-
-
Shibuya, A.1
Takeuchi, A.2
Shibata, H.3
-
16
-
-
33846463379
-
Transcriptome classification of HCC is related to gene alterations and to new therapeutic targets
-
10.1002/hep.21467 1:CAS:528:DC%2BD2sXht1arsb4%3D 17187432 10.1002/hep.21467
-
Boyault S, Rickman DS, de Reyniès A et al (2007) Transcriptome classification of HCC is related to gene alterations and to new therapeutic targets. Hepatology 45:42-52. doi: 10.1002/hep.21467
-
(2007)
Hepatology
, vol.45
, pp. 42-52
-
-
Boyault, S.1
Rickman, D.S.2
De Reyniès, A.3
-
17
-
-
79955631558
-
Genetics of hepatobiliary carcinogenesis
-
10.1055/s-0031-1276646 1:CAS:528:DC%2BC3MXotFWntrk%3D 21538283 10.1055/s-0031-1276646
-
Nault J-C, Zucman-Rossi J (2011) Genetics of hepatobiliary carcinogenesis. Semin Liver Dis 31:173-187. doi: 10.1055/s-0031-1276646
-
(2011)
Semin Liver Dis
, vol.31
, pp. 173-187
-
-
Nault, J.-C.1
Zucman-Rossi, J.2
-
18
-
-
84861625981
-
Integrated analysis of somatic mutations and focal copy-number changes identifies key genes and pathways in hepatocellular carcinoma
-
10.1038/ng.2256 1:CAS:528:DC%2BC38XmsFyjtr0%3D 3819251 22561517 10.1038/ng.2256
-
Guichard C, Amaddeo G, Imbeaud S et al (2012) Integrated analysis of somatic mutations and focal copy-number changes identifies key genes and pathways in hepatocellular carcinoma. Nat Genet 44:694-698. doi: 10.1038/ng.2256
-
(2012)
Nat Genet
, vol.44
, pp. 694-698
-
-
Guichard, C.1
Amaddeo, G.2
Imbeaud, S.3
-
19
-
-
34248674146
-
WNT/beta-catenin signaling in liver health and disease
-
10.1002/hep.21651 1:CAS:528:DC%2BD2sXlslOisr8%3D 17464972 10.1002/hep.21651
-
Thompson MD, Monga SPS (2007) WNT/beta-catenin signaling in liver health and disease. Hepatology 45:1298-1305. doi: 10.1002/hep.21651
-
(2007)
Hepatology
, vol.45
, pp. 1298-1305
-
-
Thompson, M.D.1
Monga, S.P.S.2
-
20
-
-
33645223878
-
Genotype-phenotype correlation in hepatocellular adenoma: New classification and relationship with HCC
-
10.1002/hep.21068 1:CAS:528:DC%2BD28XjtVKqsbc%3D 16496320 10.1002/hep.21068
-
Zucman-Rossi J, Jeannot E, Nhieu JTV et al (2006) Genotype-phenotype correlation in hepatocellular adenoma: new classification and relationship with HCC. Hepatology 43:515-524. doi: 10.1002/hep.21068
-
(2006)
Hepatology
, vol.43
, pp. 515-524
-
-
Zucman-Rossi, J.1
Jeannot, E.2
Nhieu, J.T.V.3
-
21
-
-
84876494014
-
Hepatocellular benign tumors-from molecular classification to personalized clinical care
-
10.1053/j.gastro.2013.02.032 1:CAS:528:DC%2BC3sXmsFCgtr0%3D 23485860 10.1053/j.gastro.2013.02.032
-
Nault J-C, Bioulac-Sage P, Zucman-Rossi J (2013) Hepatocellular benign tumors-from molecular classification to personalized clinical care. Gastroenterology 144:888-902. doi: 10.1053/j.gastro.2013.02.032
-
(2013)
Gastroenterology
, vol.144
, pp. 888-902
-
-
Nault, J.-C.1
Bioulac-Sage, P.2
Zucman-Rossi, J.3
-
22
-
-
83555161680
-
GNAS-activating mutations define a rare subgroup of inflammatory liver tumors characterized by STAT3 activation
-
10.1016/j.jhep.2011.07.018 21835143
-
Nault JC, Fabre M, Couchy G et al (2011) GNAS-activating mutations define a rare subgroup of inflammatory liver tumors characterized by STAT3 activation. J Hepatol. doi: 10.1016/j.jhep.2011.07.018
-
(2011)
J Hepatol
-
-
Nault, J.C.1
Fabre, M.2
Couchy, G.3
-
23
-
-
84872368459
-
Molecular characterization of hepatocellular adenomas developed in patients with glycogen storage disease type i
-
10.1016/j.jhep.2012.09.030
-
Calderaro J, Labrune P, Morcrette G et al (2012) Molecular characterization of hepatocellular adenomas developed in patients with glycogen storage disease type I. J Hepatol. doi: 10.1016/j.jhep.2012.09.030
-
(2012)
J Hepatol
-
-
Calderaro, J.1
Labrune, P.2
Morcrette, G.3
-
24
-
-
38649093310
-
Stabilization of beta-catenin affects mouse embryonic liver growth and hepatoblast fate
-
10.1002/hep.21952 1:CAS:528:DC%2BD1cXhtlChsb8%3D 18038450 10.1002/hep.21952
-
Decaens T, Godard C, de Reyniès A et al (2008) Stabilization of beta-catenin affects mouse embryonic liver growth and hepatoblast fate. Hepatology 47:247-258. doi: 10.1002/hep.21952
-
(2008)
Hepatology
, vol.47
, pp. 247-258
-
-
Decaens, T.1
Godard, C.2
De Reyniès, A.3
-
25
-
-
65949112714
-
Aldehyde dehydrogenase 1 is a marker for normal and malignant human colonic stem cells (SC) and tracks SC overpopulation during colon tumorigenesis
-
10.1158/0008-5472.CAN-08-4418 1:CAS:528:DC%2BD1MXksV2hsb0%3D 2789401 19336570 10.1158/0008-5472.CAN-08-4418
-
Huang EH, Hynes MJ, Zhang T et al (2009) Aldehyde dehydrogenase 1 is a marker for normal and malignant human colonic stem cells (SC) and tracks SC overpopulation during colon tumorigenesis. Cancer Res 69:3382-3389. doi: 10.1158/0008-5472.CAN-08-4418
-
(2009)
Cancer Res
, vol.69
, pp. 3382-3389
-
-
Huang, E.H.1
Hynes, M.J.2
Zhang, T.3
-
26
-
-
78649960144
-
Aldehyde dehydrogenase activity selects for lung adenocarcinoma stem cells dependent on notch signaling
-
10.1158/0008-5472.CAN-10-0881 1:CAS:528:DC%2BC3cXhsFamurjF 3058307 21118965 10.1158/0008-5472.CAN-10-0881
-
Sullivan JP, Spinola M, Dodge M et al (2010) Aldehyde dehydrogenase activity selects for lung adenocarcinoma stem cells dependent on notch signaling. Cancer Res 70:9937-9948. doi: 10.1158/0008-5472.CAN-10-0881
-
(2010)
Cancer Res
, vol.70
, pp. 9937-9948
-
-
Sullivan, J.P.1
Spinola, M.2
Dodge, M.3
-
27
-
-
84859819774
-
ALDH marks leukemia stem cell
-
10.1182/blood-2012-02-406751 1:CAS:528:DC%2BC38XmtVKgtrc%3D 22500050 10.1182/blood-2012-02-406751
-
Fleischman AG (2012) ALDH marks leukemia stem cell. Blood 119:3376-3377. doi: 10.1182/blood-2012-02-406751
-
(2012)
Blood
, vol.119
, pp. 3376-3377
-
-
Fleischman, A.G.1
-
28
-
-
34347385893
-
Cholestasis is a marker for hepatocellular carcinomas displaying beta-catenin mutations
-
10.1002/path.2169 1:CAS:528:DC%2BD2sXosVymsL4%3D 17487939 10.1002/path.2169
-
Audard V, Grimber G, Elie C et al (2007) Cholestasis is a marker for hepatocellular carcinomas displaying beta-catenin mutations. J Pathol 212:345-352. doi: 10.1002/path.2169
-
(2007)
J Pathol
, vol.212
, pp. 345-352
-
-
Audard, V.1
Grimber, G.2
Elie, C.3
-
29
-
-
0036202207
-
Cellular levels of aldehyde dehydrogenases (ALDH1A1 and ALDH3A1) as predictors of therapeutic responses to cyclophosphamide-based chemotherapy of breast cancer: A retrospective study. Rational individualization of oxazaphosphorine-based cancer chemotherapeutic regimens
-
10.1007/s00280-001-0412-4 11914911 10.1007/s00280-001-0412-4
-
Sládek NE, Kollander R, Sreerama L, Kiang DT (2002) Cellular levels of aldehyde dehydrogenases (ALDH1A1 and ALDH3A1) as predictors of therapeutic responses to cyclophosphamide-based chemotherapy of breast cancer: a retrospective study. Rational individualization of oxazaphosphorine-based cancer chemotherapeutic regimens. Cancer Chemother Pharmacol 49:309-321. doi: 10.1007/s00280-001-0412-4
-
(2002)
Cancer Chemother Pharmacol
, vol.49
, pp. 309-321
-
-
Sládek, N.E.1
Kollander, R.2
Sreerama, L.3
Kiang, D.T.4
-
30
-
-
33751300540
-
RNAi-mediated knockdown of aldehyde dehydrogenase class-1A1 and class-3A1 is specific and reveals that each contributes equally to the resistance against 4-hydroperoxycyclophosphamide
-
10.1007/s00280-006-0233-6 1:CAS:528:DC%2BD28Xht1entL%2FO 16614850 10.1007/s00280-006-0233-6
-
Moreb JS, Mohuczy D, Muhoczy D et al (2007) RNAi-mediated knockdown of aldehyde dehydrogenase class-1A1 and class-3A1 is specific and reveals that each contributes equally to the resistance against 4-hydroperoxycyclophosphamide. Cancer Chemother Pharmacol 59:127-136. doi: 10.1007/s00280-006-0233-6
-
(2007)
Cancer Chemother Pharmacol
, vol.59
, pp. 127-136
-
-
Moreb, J.S.1
Mohuczy, D.2
Muhoczy, D.3
-
31
-
-
57849134562
-
MTDH activation by 8q22 genomic gain promotes chemoresistance and metastasis of poor-prognosis breast cancer
-
10.1016/j.ccr.2008.11.013 1:CAS:528:DC%2BD1MXptVGqtA%3D%3D 2676231 19111877 10.1016/j.ccr.2008.11.013
-
Hu G, Chong RA, Yang Q et al (2009) MTDH activation by 8q22 genomic gain promotes chemoresistance and metastasis of poor-prognosis breast cancer. Cancer Cell 15:9-20. doi: 10.1016/j.ccr.2008.11.013
-
(2009)
Cancer Cell
, vol.15
, pp. 9-20
-
-
Hu, G.1
Chong, R.A.2
Yang, Q.3
-
32
-
-
84879465430
-
A hepatocellular carcinoma 5-gene score associated with survival of patients after liver resection
-
10.1053/j.gastro.2013.03.051 1:CAS:528:DC%2BC3sXhtVSlsLzP 23567350 10.1053/j.gastro.2013.03.051
-
Nault J-C, De Reyniès A, Villanueva A et al (2013) A hepatocellular carcinoma 5-gene score associated with survival of patients after liver resection. Gastroenterology 145:176-187. doi: 10.1053/j.gastro.2013.03. 051
-
(2013)
Gastroenterology
, vol.145
, pp. 176-187
-
-
Nault, J.-C.1
De Reyniès, A.2
Villanueva, A.3
-
33
-
-
0034495080
-
Beta-catenin mutations are associated with a subset of low-stage hepatocellular carcinoma negative for hepatitis B virus and with favorable prognosis
-
1:CAS:528:DC%2BD3cXmvFWqt78%3D 10980116 10.1016/S0002-9440(10)64590-7
-
Hsu HC, Jeng YM, Mao TL et al (2000) Beta-catenin mutations are associated with a subset of low-stage hepatocellular carcinoma negative for hepatitis B virus and with favorable prognosis. Am J Pathol 157:763-770
-
(2000)
Am J Pathol
, vol.157
, pp. 763-770
-
-
Hsu, H.C.1
Jeng, Y.M.2
Mao, T.L.3
-
34
-
-
77349092851
-
Molecular classification and novel targets in hepatocellular carcinoma: Recent advancements
-
10.1055/s-0030-1247131 1:CAS:528:DC%2BC3cXjvFCqtbg%3D 3668687 20175032 10.1055/s-0030-1247131
-
Hoshida Y, Toffanin S, Lachenmayer A et al (2010) Molecular classification and novel targets in hepatocellular carcinoma: recent advancements. Semin Liver Dis 30:35-51. doi: 10.1055/s-0030-1247131
-
(2010)
Semin Liver Dis
, vol.30
, pp. 35-51
-
-
Hoshida, Y.1
Toffanin, S.2
Lachenmayer, A.3
-
35
-
-
79955401037
-
Combining clinical, pathology, and gene expression data to predict recurrence of hepatocellular carcinoma
-
10.1053/j.gastro.2011.02.006 1:CAS:528:DC%2BC3MXlt1Smurs%3D 3081971 21320499 10.1053/j.gastro.2011.02.006
-
Villanueva A, Hoshida Y, Battiston C et al (2011) Combining clinical, pathology, and gene expression data to predict recurrence of hepatocellular carcinoma. Gastroenterology 140:1501-1512.e2. doi: 10.1053/j.gastro.2011.02.006
-
(2011)
Gastroenterology
, vol.140
-
-
Villanueva, A.1
Hoshida, Y.2
Battiston, C.3
-
36
-
-
84866532501
-
Wnt-pathway activation in two molecular classes of hepatocellular carcinoma and experimental modulation by sorafenib
-
10.1158/1078-0432.CCR-11-2322 1:CAS:528:DC%2BC38Xhtl2lt73N 3446854 22811581 10.1158/1078-0432.CCR-11-2322
-
Lachenmayer A, Alsinet C, Savic R et al (2012) Wnt-pathway activation in two molecular classes of hepatocellular carcinoma and experimental modulation by sorafenib. Clin Cancer Res 18:4997-5007. doi: 10.1158/1078-0432.CCR-11-2322
-
(2012)
Clin Cancer Res
, vol.18
, pp. 4997-5007
-
-
Lachenmayer, A.1
Alsinet, C.2
Savic, R.3
|