메뉴 건너뛰기




Volumn 34, Issue 7, 2014, Pages 2444-2450

Bdnf deletion or TrkB impairment in amygdala inhibits both appetitive and aversive learning

Author keywords

Amygdala; BDNF; Learning; TrkB

Indexed keywords

AMYGDALA; BDNF; LEARNING; TRKB;

EID: 84893639126     PISSN: 02706474     EISSN: 15292401     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.4085-12.2014     Document Type: Article
Times cited : (40)

References (34)
  • 1
    • 24144483438 scopus 로고    scopus 로고
    • BDNF function in adult synaptic plasticity: The synaptic consolidation hypothesis
    • CrossRef Medline
    • Bramham CR, Messaoudi E (2005) BDNF function in adult synaptic plasticity: the synaptic consolidation hypothesis. Prog Neurobiol 76:99-125. CrossRef Medline
    • (2005) Prog Neurobiol , vol.76 , pp. 99-125
    • Bramham, C.R.1    Messaoudi, E.2
  • 2
    • 26844482700 scopus 로고    scopus 로고
    • Brain-derived neurotrophic factor (Val66Met) genetic polymorphism is associated with substance abuse in males
    • CrossRef Medline
    • Cheng CY, Hong CJ, Yu YW, Chen TJ, Wu HC, Tsai SJ (2005) Brain-derived neurotrophic factor (Val66Met) genetic polymorphism is associated with substance abuse in males. Brain Res Mol Brain Res 140:86-90. CrossRef Medline
    • (2005) Brain Res Mol Brain Res , vol.140 , pp. 86-90
    • Cheng, C.Y.1    Hong, C.J.2    Yu, Y.W.3    Chen, T.J.4    Wu, H.C.5    Tsai, S.J.6
  • 3
    • 33745582492 scopus 로고    scopus 로고
    • Amygdala BDNF signaling is required for consolidation but not encoding of extinction
    • CrossRef Medline
    • Chhatwal JP, Stanek-Rattiner L, Davis M, Ressler KJ (2006) Amygdala BDNF signaling is required for consolidation but not encoding of extinction. Nat Neurosci 9:870-872. CrossRef Medline
    • (2006) Nat Neurosci , vol.9 , pp. 870-872
    • Chhatwal, J.P.1    Stanek-Rattiner, L.2    Davis, M.3    Ressler, K.J.4
  • 4
    • 77249140499 scopus 로고    scopus 로고
    • Prelimbic cortical BDNF is required for memory of learned fear but not extinction or innate fear
    • CrossRef Medline
    • Choi DC, Maguschak KA, Ye K, Jang SW, Myers KM, Ressler KJ (2010) Prelimbic cortical BDNF is required for memory of learned fear but not extinction or innate fear. Proc Natl Acad Sci U S A 107:2675-2680. CrossRef Medline
    • (2010) Proc Natl Acad Sci U S A , vol.107 , pp. 2675-2680
    • Choi, D.C.1    Maguschak, K.A.2    Ye, K.3    Jang, S.W.4    Myers, K.M.5    Ressler, K.J.6
  • 5
    • 77952349119 scopus 로고    scopus 로고
    • Brain-derived neurotrophic factor: A dynamic gatekeeper of neural plasticity
    • CrossRef Medline
    • Cowansage KK, Le Doux JE, Monfils MH (2010) Brain-derived neurotrophic factor: a dynamic gatekeeper of neural plasticity. Curr Mol Pharmacol 3:12-29. CrossRef Medline
    • (2010) Curr Mol Pharmacol , vol.3 , pp. 12-29
    • Cowansage, K.K.1    Le Doux, J.E.2    Monfils, M.H.3
  • 6
    • 0026535166 scopus 로고
    • The role of the amygdala in fear and anxiety
    • CrossRef Medline
    • Davis M (1992) The role of the amygdala in fear and anxiety. Annu Rev Neurosci 15:353-375. CrossRef Medline
    • (1992) Annu Rev Neurosci , vol.15 , pp. 353-375
    • Davis, M.1
  • 7
    • 0037276699 scopus 로고    scopus 로고
    • Appetitive behavior: Impact of amygdala-dependent mechanisms of emotional learning
    • CrossRef Medline
    • Everitt BJ, Cardinal RN, Parkinson JA, Robbins TW (2003) Appetitive behavior: impact of amygdala-dependent mechanisms of emotional learning. Ann N Y Acad Sci 985:233-250. CrossRef Medline
    • (2003) Ann N Y Acad Sci , vol.985 , pp. 233-250
    • Everitt, B.J.1    Cardinal, R.N.2    Parkinson, J.A.3    Robbins, T.W.4
  • 8
    • 0033153226 scopus 로고    scopus 로고
    • Why we think plasticity underlying Pavlovian fear conditioning occurs in the basolateral amygdala
    • CrossRef Medline
    • Fanselow MS, Le Doux JE (1999) Why we think plasticity underlying Pavlovian fear conditioning occurs in the basolateral amygdala. Neuron 23: 229-232. CrossRef Medline
    • (1999) Neuron , vol.23 , pp. 229-232
    • Fanselow, M.S.1    Le Doux, J.E.2
  • 9
    • 78149267659 scopus 로고    scopus 로고
    • Variant brain-derived neurotrophic factor Val66Met endophenotypes: Implications for posttraumatic stress disorder
    • CrossRef Medline
    • Frielingsdorf H, Bath KG, Soliman F, Difede J, Casey BJ, Lee FS (2010) Variant brain-derived neurotrophic factor Val66Met endophenotypes: implications for posttraumatic stress disorder. Ann N Y Acad Sci 1208: 150-157. CrossRef Medline
    • (2010) Ann N Y Acad Sci , vol.1208 , pp. 150-157
    • Frielingsdorf, H.1    Bath, K.G.2    Soliman, F.3    Difede, J.4    Casey, B.J.5    Lee, F.S.6
  • 10
    • 0036498266 scopus 로고    scopus 로고
    • Effects of excitotoxic lesions of the basolateral amygdala on cocaine-seeking behavior and cocaine conditioned place preference in rats
    • CrossRef Medline
    • Fuchs RA, Weber SM, Rice HJ, Neisewander JL (2002) Effects of excitotoxic lesions of the basolateral amygdala on cocaine-seeking behavior and cocaine conditioned place preference in rats. Brain Res 929:15-25. CrossRef Medline
    • (2002) Brain Res , vol.929 , pp. 15-25
    • Fuchs, R.A.1    Weber, S.M.2    Rice, H.J.3    Neisewander, J.L.4
  • 11
    • 0036433355 scopus 로고    scopus 로고
    • Long-term potentiation as a substrate for memory: Evidence from studies of amygdaloid plasticity and Pavlovian fear conditioning
    • CrossRef Medline
    • Goosens KA, Maren S (2002) Long-term potentiation as a substrate for memory: evidence from studies of amygdaloid plasticity and Pavlovian fear conditioning. Hippocampus 12:592-599. CrossRef Medline
    • (2002) Hippocampus , vol.12 , pp. 592-599
    • Goosens, K.A.1    Maren, S.2
  • 12
    • 0037044850 scopus 로고    scopus 로고
    • Regulation of TRKB surface expression by brainderived neurotrophic factor and truncated TRKB isoforms
    • CrossRef Medline
    • Haapasalo A, Sipola I, Larsson K, Akerman KE, Stoilov P, Stamm S, Wong G, Castren E (2002) Regulation of TRKB surface expression by brainderived neurotrophic factor and truncated TRKB isoforms. J Biol Chem 277:43160-43167. CrossRef Medline
    • (2002) J Biol Chem , vol.277 , pp. 43160-43167
    • Haapasalo, A.1    Sipola, I.2    Larsson, K.3    Akerman, K.E.4    Stoilov, P.5    Stamm, S.6    Wong, G.7    Castren, E.8
  • 13
    • 77953048850 scopus 로고    scopus 로고
    • Amygdala-specific reduction of alpha1-GABAA receptors disrupts the anticonvulsant, locomotor, and sedative, but not anxiolytic, effects of benzodiazepines in mice
    • Medline
    • Heldt SA, Ressler KJ (2010) Amygdala-specific reduction of alpha1-GABAA receptors disrupts the anticonvulsant, locomotor, and sedative, but not anxiolytic, effects of benzodiazepines in mice. J Neurosci 30:7139-7151. Medline
    • (2010) J Neurosci , vol.30 , pp. 7139-7151
    • Heldt, S.A.1    Ressler, K.J.2
  • 14
    • 34247856252 scopus 로고    scopus 로고
    • Hippocampus-specific deletion of BDNF in adult mice impairs spatial memory and extinction of aversive memories
    • CrossRef Medline
    • Heldt SA, Stanek L, Chhatwal JP, Ressler KJ (2007) Hippocampus-specific deletion of BDNF in adult mice impairs spatial memory and extinction of aversive memories. Mol Psychiatry 12:656-670. CrossRef Medline
    • (2007) Mol Psychiatry , vol.12 , pp. 656-670
    • Heldt, S.A.1    Stanek, L.2    Chhatwal, J.P.3    Ressler, K.J.4
  • 15
    • 0029021177 scopus 로고
    • Hippocampal long-term potentiation is impaired in mice lacking brainderived neurotrophic factor
    • Medline
    • Korte M, Carroll P, Wolf E, Brem G, Thoenen H, Bonhoeffer T (1995) Hippocampal long-term potentiation is impaired in mice lacking brainderived neurotrophic factor. Proc Natl Acad Sci U S A 92:8856-8860. Medline
    • (1995) Proc Natl Acad Sci U S A , vol.92 , pp. 8856-8860
    • Korte, M.1    Carroll, P.2    Wolf, E.3    Brem, G.4    Thoenen, H.5    Bonhoeffer, T.6
  • 16
    • 38849198650 scopus 로고    scopus 로고
    • Expression of trk B and trk C receptors and their ligands brain-derived neurotrophic factor and neurotrophin-3 in the murine amygdala
    • CrossRef Medline
    • Krause S, Schindowski K, Zechel S, von Bohlen und Halbach O (2008) Expression of trk B and trk C receptors and their ligands brain-derived neurotrophic factor and neurotrophin-3 in the murine amygdala. J Neurosci Res 86:411-421. CrossRef Medline
    • (2008) J Neurosci Res , vol.86 , pp. 411-421
    • Krause, S.1    Schindowski, K.2    Zechel, S.3    von Bohlen4    Halbach, O.5
  • 17
    • 0027434646 scopus 로고
    • CNS glial cells express neurotrophin receptors whose levels are regulated by NGF
    • Medline
    • Kumar S, Peña LA, de Vellis J (1993) CNS glial cells express neurotrophin receptors whose levels are regulated by NGF. Brain Res Mol Brain Res 17:163-168. Medline
    • (1993) Brain Res Mol Brain Res , vol.17 , pp. 163-168
    • Kumar, S.1    Peña, L.A.2    de Vellis, J.3
  • 18
    • 80054705607 scopus 로고    scopus 로고
    • Synergistic activation of dopamine D1 and Trk B receptors mediate gain control of synaptic plasticity in the basolateral amygdala
    • CrossRef Medline
    • Li C, Dabrowska J, Hazra R, Rainnie DG (2011) Synergistic activation of dopamine D1 and Trk B receptors mediate gain control of synaptic plasticity in the basolateral amygdala. PLo S One 6:e26065. CrossRef Medline
    • (2011) PLo S One , vol.6
    • Li, C.1    Dabrowska, J.2    Hazra, R.3    Rainnie, D.G.4
  • 19
    • 0032168991 scopus 로고    scopus 로고
    • Expression of a dominant-negative Trk B receptor, T1, reveals a requirement for presynaptic signaling in BDNF-induced synaptic potentiation in cultured hippocampal neurons
    • Medline
    • Li YX, Xu Y, Ju D, Lester HA, Davidson N, Schuman EM (1998) Expression of a dominant-negative Trk B receptor, T1, reveals a requirement for presynaptic signaling in BDNF-induced synaptic potentiation in cultured hippocampal neurons. Proc Natl Acad Sci U S A 95:10884-10889. Medline
    • (1998) Proc Natl Acad Sci U S A , vol.95 , pp. 10884-10889
    • Li, Y.X.1    Xu, Y.2    Ju, D.3    Lester, H.A.4    Davidson, N.5    Schuman, E.M.6
  • 20
    • 77249178282 scopus 로고    scopus 로고
    • Amygdala-dependent fear conditioning in humans is modulated by the BDNFval66met polymorphism
    • CrossRef Medline
    • Lonsdorf TB, Weike AI, Golkar A, Schalling M, Hamm AO, Ohman A (2010) Amygdala-dependent fear conditioning in humans is modulated by the BDNFval66met polymorphism. Behav Neurosci 124:9-15. CrossRef Medline
    • (2010) Behav Neurosci , vol.124 , pp. 9-15
    • Lonsdorf, T.B.1    Weike, A.I.2    Golkar, A.3    Schalling, M.4    Hamm, A.O.5    Ohman, A.6
  • 21
    • 1242319311 scopus 로고    scopus 로고
    • A single infusion of brain-derived neurotrophic factor into the ventral tegmental area induces long-lasting potentiation of cocaine seeking after withdrawal
    • CrossRef Medline
    • Lu L, Dempsey J, Liu SY, Bossert JM, Shaham Y (2004) A single infusion of brain-derived neurotrophic factor into the ventral tegmental area induces long-lasting potentiation of cocaine seeking after withdrawal. J Neurosci 24:1604-1611. CrossRef Medline
    • (2004) J Neurosci , vol.24 , pp. 1604-1611
    • Lu, L.1    Dempsey, J.2    Liu, S.Y.3    Bossert, J.M.4    Shaham, Y.5
  • 22
    • 84855175745 scopus 로고    scopus 로고
    • Postsynaptic BDNF signaling regulates long-term potentiation at thalamo-amygdala afferents
    • CrossRef Medline
    • Meis S, Endres T, Lessmann V (2012) Postsynaptic BDNF signaling regulates long-term potentiation at thalamo-amygdala afferents. J Physiol 590: 193-208. CrossRef Medline
    • (2012) J Physiol , vol.590 , pp. 193-208
    • Meis, S.1    Endres, T.2    Lessmann, V.3
  • 24
    • 0037007995 scopus 로고    scopus 로고
    • BDNF binding to truncated trk B. T1 does not affect gene expression
    • Medline
    • Offenhäuser N, Muzio V, Biffo S (2002) BDNF binding to truncated trk B. T1 does not affect gene expression. Neuroreport 13:1189-1193. Medline
    • (2002) Neuroreport , vol.13 , pp. 1189-1193
    • Offenhäuser, N.1    Muzio, V.2    Biffo, S.3
  • 25
    • 30944458206 scopus 로고    scopus 로고
    • Regulation of amygdala-dependent learning by brain-derived neurotrophic factor is mediated by extracellular signalregulated kinase and phosphatidylinositol-3-kinase
    • CrossRef Medline
    • Ou LC, Gean PW (2006) Regulation of amygdala-dependent learning by brain-derived neurotrophic factor is mediated by extracellular signalregulated kinase and phosphatidylinositol-3-kinase. Neuropsychopharmacology 31:287-296. CrossRef Medline
    • (2006) Neuropsychopharmacology , vol.31 , pp. 287-296
    • Ou, L.C.1    Gean, P.W.2
  • 28
    • 2442655323 scopus 로고    scopus 로고
    • Brain-derived neurotrophic factor and tyrosine kinase receptor B involvement in amygdala-dependent fear conditioning
    • CrossRef Medline
    • Rattiner LM, Davis M, French CT, Ressler KJ (2004) Brain-derived neurotrophic factor and tyrosine kinase receptor B involvement in amygdala-dependent fear conditioning. J Neurosci 24:4796-4806. CrossRef Medline
    • (2004) J Neurosci , vol.24 , pp. 4796-4806
    • Rattiner, L.M.1    Davis, M.2    French, C.T.3    Ressler, K.J.4
  • 29
    • 22844449978 scopus 로고    scopus 로고
    • Brain-derived neurotrophic factor in amygdala-dependent learning
    • CrossRef Medline
    • Rattiner LM, Davis M, Ressler KJ (2005) Brain-derived neurotrophic factor in amygdala-dependent learning. Neuroscientist 11:323-333. CrossRef Medline
    • (2005) Neuroscientist , vol.11 , pp. 323-333
    • Rattiner, L.M.1    Davis, M.2    Ressler, K.J.3
  • 30
    • 0037107121 scopus 로고    scopus 로고
    • Regulation of synaptic plasticity genes during consolidation of fear conditioning
    • Medline
    • Ressler KJ, Paschall G, Zhou XL, Davis M (2002) Regulation of synaptic plasticity genes during consolidation of fear conditioning. J Neurosci 22: 7892-7902. Medline
    • (2002) J Neurosci , vol.22 , pp. 7892-7902
    • Ressler, K.J.1    Paschall, G.2    Zhou, X.L.3    Davis, M.4
  • 31
    • 0031471239 scopus 로고    scopus 로고
    • Fear conditioning induces associative long-term potentiation in the amygdala
    • CrossRef Medline
    • Rogan MT, Stäubli UV, Le Doux JE (1997) Fear conditioning induces associative long-term potentiation in the amygdala. Nature 390:604-607. CrossRef Medline
    • (1997) Nature , vol.390 , pp. 604-607
    • Rogan, M.T.1    Stäubli, U.V.2    Le Doux, J.E.3
  • 33
    • 77549087500 scopus 로고    scopus 로고
    • The brain-derived neurotrophic factor Val66Met polymorphism affects memory formation and retrieval of biologically salient stimuli
    • CrossRef Medline
    • van Wingen G, Rijpkema M, Franke B, van Eijndhoven P, Tendolkar I, Verkes RJ, Buitelaar J, Fernández G (2010) The brain-derived neurotrophic factor Val66Met polymorphism affects memory formation and retrieval of biologically salient stimuli. Neuroimage 50:1212-1218. CrossRef Medline
    • (2010) Neuroimage , vol.50 , pp. 1212-1218
    • van Wingen, G.1    Rijpkema, M.2    Franke, B.3    van Eijndhoven, P.4    Tendolkar, I.5    Verkes, R.J.6    Buitelaar, J.7    Fernández, G.8
  • 34
    • 0027161055 scopus 로고
    • Distribution of trk B tyrosine kinase immunoreactivity in the rat central nervous system
    • CrossRef Medline
    • Zhou XF, Parada LF, Soppet D, Rush RA (1993) Distribution of trk B tyrosine kinase immunoreactivity in the rat central nervous system. Brain Res 622:63-70. CrossRef Medline
    • (1993) Brain Res , vol.622 , pp. 63-70
    • Zhou, X.F.1    Parada, L.F.2    Soppet, D.3    Rush, R.A.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.