Spirometry and health status worsen with weight gain in obese smokers but improve in normal-weight smokers

American Journal of Respiratory and Critical Care Medicine

Volumn 189, Issue 3, 2014, Pages 274-281

  Sood, Akshay ^a   Petersen, Hans ^b   Meek, Paula ^c   Tesfaigzi, Yohannes ^b  

^a UNIVERSITY OF NEW MEXICO SCHOOL OF MEDICINE   (United States)

^b LOVELACE RESPIRATORY RESEARCH INSTITUTE   (United States)

^c UNIVERSITY OF COLORADO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BRONCHODILATING AGENT;

ADULT; AGED; ARTICLE; BODY MASS; CHRONIC BRONCHITIS; CHRONIC OBSTRUCTIVE LUNG DISEASE; CONTROLLED STUDY; COUGHING; CROSS-SECTIONAL STUDY; DIABETES MELLITUS; DISEASE ASSOCIATION; DYSPNEA; ENVIRONMENTAL EXPOSURE; FEMALE; FOLLOW UP; FORCED EXPIRATORY VOLUME; FORCED VITAL CAPACITY; HEALTH STATUS; HISPANIC; HUMAN; HYPERTENSION; LONGITUDINAL STUDY; MAJOR CLINICAL STUDY; MALE; MIDDLE AGED; OBESITY; PRIORITY JOURNAL; RISK FACTOR; SMOKING; SMOKING HABIT; SOCIAL STATUS; SPIROMETRY; ST. GEORGE RESPIRATORY QUESTIONNAIRE; WEIGHT GAIN; WEIGHT REDUCTION; WHEEZING;

ADULT; AGED; BODY MASS INDEX; CROSS-SECTIONAL STUDIES; FEMALE; FOLLOW-UP STUDIES; FORCED EXPIRATORY VOLUME; HEALTH STATUS; HEALTH STATUS INDICATORS; HUMANS; LINEAR MODELS; LOGISTIC MODELS; MALE; MIDDLE AGED; OBESITY; PULMONARY DISEASE, CHRONIC OBSTRUCTIVE; QUESTIONNAIRES; RISK FACTORS; SMOKING; SPIROMETRY; WEIGHT GAIN;

EID: 84893593514     PISSN: 1073449X     EISSN: 15354970     Source Type: Journal    
DOI: 10.1164/rccm.201306-1060OC     Document Type: Article

References (49)

1. World Health Organization Global Health Observatory. Obesity: situation and trends. 2013 [accessed 2013 Aug 1]. Available from: http://www.Who.Int/gho/ ncd/risk-factors/obesity-text/en/index.html
2. Ogden CL, Carroll MD, Kit BK, Flegal KM. Prevalence of obesity in the United States, 2009-2010. NCHS data brief. Hyattsville, MD: National Center for Health Statistics; 2012. pp. 1-8.
3. Masters RK, Reither EN, Powers DA, Yang YC, Burger AE, Link BG. The impact of obesity on USmortality levels: the importance of age and cohort factors in population estimates. Am J Public Health 2013;103:1895-1901.
4. Masters RK, Powers DA, Link BG. Obesity and US mortality risk over the adult life course. Am J Epidemiol 2013;177:431-442.
5. Szulińska M, Piorunek T, Suliburska J, Pupek-Musialik D, Kupsz J, Drzymala-Czyż S, Bogdański P. Evaluation of insulin resistance, tumor necrosis factor alpha, and total antioxidant status in obese patients smoking cigarettes. Eur Rev Med Pharmacol Sci 2013;17:1916-1922.
6. Komakula S, Khatri S, Mermis J, Savill S, Haque S, Rojas M, Brown L, Teague GW, Holguin F. Body mass index is associated with reduced exhaled nitric oxide and higher exhaled 8-isoprostanes in asthmatics. Respir Res 2007;8:32.
7. Sutherland TJ, Cowan JO, Young S, Goulding A, Grant AM, Williamson A, Brassett K, Herbison GP, Taylor DR. The association between obesity and asthma: interactions between systemic and airway inflammation. Am J Respir Crit Care Med 2008;178:469-475.
8. van der Vaart H, Postma DS, Timens W, ten Hacken NH. Acute effects of cigarette smoke on inflammation and oxidative stress: a review. Thorax 2004;59:713-721.
9. Jee SH, Sull JW, Park J, Lee SY, Ohrr H, Guallar E, Samet JM. Bodymass index and mortality in Korean men and women. N Engl J Med 2006;355:779-787.
10. Vestbo J, Prescott E, Almdal T, Dahl M, Nordestgaard BG, Andersen T, Sørensen TI, Lange P. Body mass, fat-free body mass, and prognosis in patients with chronic obstructive pulmonary disease from a random population sample: findings from the Copenhagen City Heart Study. Am J Respir Crit Care Med 2006;173:79-83.
11. Landbo C, Prescott E, Lange P, Vestbo J, Almdal TP. Prognostic value of nutritional status in chronic obstructive pulmonary disease. Am J Respir Crit Care Med 1999;160:1856-1861.
12. Ora J, Laveneziana P, Ofir D, Deesomchok A, Webb KA, O'Donnell DE. Combined effects of obesity and chronic obstructive pulmonary disease on dyspnea and exercise tolerance. Am J Respir Crit Care Med 2009;180:964-971.
13. Thyagarajan B, Jacobs DR Jr, Apostol GG, Smith LJ, Jensen RL, Crapo RO, Barr RG, Lewis CE, Williams OD. Longitudinal association of body mass index with lung function: the CARDIA study. Respir Res 2008;9:31.
14. O'Donnell DE, O'Donnell CD, Webb KA, Guenette JA. Respiratory consequences of mild-to-moderate obesity: impact on exercise performance in health and in chronic obstructive pulmonary disease. Pulm Med 2012;2012:818925.
15. Schoenborn CA, Adams PE. Health behaviors of adults: United States, 2005-2007. Vital Health Stat 10 2010-2010;2013:1-132.
16. Silverman EK, Weiss ST, Drazen JM, Chapman HA, Carey V, Campbell EJ, Denish P, Silverman RA, Celedon JC, Reilly JJ, et al. Genderrelated differences in severe, early-onset chronic obstructive pulmonary disease. Am J Respir Crit Care Med 2000;162: 2152-2158.
17. Sood A, Stidley CA, Picchi MA, Celedón JC, Gilliland F, Crowell RE, Belinsky SA, Tesfaigzi Y. Difference in airflow obstruction between Hispanic and non-Hispanic white female smokers. COPD 2008;5: 274-281.
18. Bruse S, Sood A, Petersen H, Liu Y, Leng S, Celedón JC, Gilliland F, Celli B, Belinsky SA, Tesfaigzi Y. New Mexican Hispanic smokers have lower odds of chronic obstructive pulmonary disease and less decline in lung function than non-Hispanic whites. Am J Respir Crit Care Med 2011;184:1254-1260.
19. Taylor B, Mannino D, Brown C, Crocker D, Twum-Baah N, Holguin F. Body mass index and asthma severity in the National Asthma Survey. Thorax 2008;63:14-20.
20. Vortmann M, Eisner MD. BMI and health status among adults with asthma. Obesity (Silver Spring) 2008;16:146-152.
21. Mosen DM, Schatz M, Magid DJ, Camargo CA Jr. The relationship between obesity and asthma severity and control in adults. J Allergy Clin Immunol 2008;122:507-511, e6.
22. Tantisira KG, Litonjua AA, Weiss ST, Fuhlbrigge AL; Childhood Asthma Management Program Research Group. Association of body mass with pulmonary function in the Childhood Asthma Management Program (CAMP). Thorax 2003;58:1036-1041.
23. European Network for Understanding Mechanisms of Severe Asthma. The ENFUMOSA cross-sectional European multicentre study of the clinical phenotype of chronic severe asthma. Eur Respir J 2003;22:470-477.
24. Sutherland ER, Lehman EB, Teodorescu M, Wechsler ME. Body mass index and phenotype in subjects with mild-to-moderate persistent asthma. J Allergy Clin Immunol 2009;123:1328-1334, e1.
25. Wenzel SE, Busse WW. Severe asthma: lessons from the Severe Asthma Research Program. J Allergy Clin Immunol 2007;119:14-21. quiz 22-23.
26. Ferris BG. Epidemiology standardization project (American Thoracic Society). Am Rev Respir Dis 1978;118:1-120.
27. Jones PW, Quirk FH, Baveystock CM, Littlejohns P. A self-complete measure of health status for chronic airflow limitation: the St. George's Respiratory Questionnaire. Am Rev Respir Dis 1992;145: 1321-1327.
28. Jones PW. St. George's Respiratory Questionnaire: MCID. COPD 2005; 2:75-79.
29. Heijdra YF, Pinto-Plata VM, Kenney LA, Rassulo J, Celli BR. Cough and phlegm are important predictors of health status in smokers without COPD. Chest 2002;121:1427-1433.
30. Kirby M, Owrangi A, Svenningsen S, Wheatley A, Coxson HO, Paterson NA, McCormack DG, Parraga G. On the role of abnormal DL(CO) in ex-smokers without airflow limitation: symptoms, exercise capacity and hyperpolarised helium-3 MRI. Thorax 2013;68:752-759.
31. Nishimura K, Mitsuma S, Kobayashi A, Yanagida M, Nakayasu K, Hasegawa Y, Jones PW. COPD and disease-specific health status in a working population. Respir Res 2013;14:61.
32. Ferrer M, Villasante C, Alonso J, Sobradillo V, Gabriel R, Vilagut G, Masa JF, Viejo JL, Jiménez-Ruiz CA, Miravitlles M. Interpretation of quality of life scores from the St George's Respiratory Questionnaire. Eur Respir J 2002;19:405-413.
33. American Thoracic Society. Standardization of spirometry, 1994 update. Am J Respir Crit Care Med 1995;152:1107-1136.
34. Grinker JA, Tucker K, Vokonas PS, Rush D. Body habitus changes among adult males from the normative aging study: relations to aging, smoking history and alcohol intake. Obes Res 1995;3: 435-446.
35. Nakamura Y, Sekikawa A, Kadowaki T, Kadota A, Kadowaki S, Maegawa H, Kita Y, Evans RW, Edmundowicz D, Curb JD, et al. Visceral and subcutaneous adiposity and adiponectin in middle-aged Japanese men: the ERA JUMP study. Obesity (Silver Spring) 2009;17:1269-1273.
36. Guerra S, Sherrill DL, Bobadilla A, Martinez FD, Barbee RA. The relation of body mass index to asthma, chronic bronchitis, and emphysema. Chest 2002;122:1256-1263.
37. Rakhimova E, Wiehlmann L, Brauer AL, Sethi S, Murphy TF, Tümmler B. Pseudomonas aeruginosa population biology in chronic obstructive pulmonary disease. J Infect Dis 2009;200:1928-1935.
38. Sethi S, Murphy TF. Infection in the pathogenesis and course of chronic obstructive pulmonary disease. N Engl J Med 2008;359:2355-2365.
39. Han MK, Postma D, Mannino DM, Giardino ND, Buist S, Curtis JL, Martinez FJ. Gender and chronic obstructive pulmonary disease: why it matters. Am J Respir Crit Care Med 2007;176:1179-1184.
40. Vozoris NT, O'Donnell DE. Prevalence, risk factors, activity limitation and health care utilization of an obese, population-based sample with chronic obstructive pulmonary disease. Can Respir J 2012;19:e18-e24.
41. Barr RG, Herbstman J, Speizer FE, Camargo CA Jr. Validation of selfreported chronic obstructive pulmonary disease in a cohort study of nurses. Am J Epidemiol 2002;155:965-971.
42. Harik-Khan RI, Fleg JL, Wise RA. Body mass index and the risk of COPD. Chest 2002;121:370-376.
43. Sood A. Altered resting and exercise respiratory physiology in obesity. Clin Chest Med 2009;30:445-454, vii.
44. Cao C, Wang R, Wang J, Bunjhoo H, Xu Y, Xiong W. Body mass index and mortality in chronic obstructive pulmonary disease: a metaanalysis. PLoS ONE 2012;7:e43892.
45. Schols AM, Broekhuizen R, Weling-Scheepers CA, Wouters EF. Body composition and mortality in chronic obstructive pulmonary disease. Am J Clin Nutr 2005;82:53-59.
46. Wannamethee SG, Shaper AG, Whincup PH. Body fat distribution, body composition, and respiratory function in elderly men. Am J Clin Nutr 2005;82:996-1003.
47. Sutherland TJ, Goulding A, Grant AM, Cowan JO, Williamson A, Williams SM, Skinner MA, Taylor DR. The effect of adiposity measured by dual-energy X-ray absorptiometry on lung function. Eur Respir J 2008;32:85-91.
48. Centers for Disease Control and Prevention (CDC). Behavioral risk factor surveillance system survey data. Atlanta, GA: Centers for Disease Control and Prevention; 2006.
49. Hankinson JL, Odencrantz JR, Fedan KB. Spirometric reference values from a sample of the general U.S. population. Am J Respir Crit Care Med 1999;159:179-187.