Quantitative assessment of cerebral glucose metabolic rates after blood-brain barrier disruption induced by focused ultrasound using FDG-MicroPET

NeuroImage

Volumn 90, Issue , 2014, Pages 93-98

  Yang, Feng Yi ^a   Chang, Wen Yuan ^a   Chen, Jyh Cheng ^a   Lee, Lin Chien ^b   Hung, Yi Shun ^a  

^a NATIONAL YANG MING UNIVERSITY   (Taiwan)

^b CHENG HSIN GENERAL HOSPITAL   (Taiwan)

Author keywords

18F FDG; Blood brain barrier disruption; Focused ultrasound; MicroPET; Pharmacokinetics

Indexed keywords

(18)F-FDG; BLOOD-BRAIN BARRIER DISRUPTION; FOCUSED ULTRASOUND; MICROPET; PHARMACOKINETICS;

ANIMALS; BLOOD-BRAIN BARRIER; BLOTTING, WESTERN; BRAIN; GLUCOSE; GLUCOSE TRANSPORTER TYPE 1; GLUCOSE-6-PHOSPHATE; MALE; POSITRON-EMISSION TOMOGRAPHY; RADIOPHARMACEUTICALS; RATS; RATS, SPRAGUE-DAWLEY; ULTRASONOGRAPHY;

EID: 84893569405     PISSN: 10538119     EISSN: 10959572     Source Type: Journal    
DOI: 10.1016/j.neuroimage.2013.12.033     Document Type: Article

References (29)

1. Abbott N.J., Romero I.A. Transporting therapeutics across the blood-brain barrier. Mol. Med. Today 1996, 2:106-113.
2. Avril N. GLUT1 expression in tissue and (18)F-FDG uptake. J. Nucl. Med. 2004, 45:930-932.
3. Choi J.J., Pernot M., Small S.A., Konofagou E.E. Noninvasive, transcranial and localized opening of the blood-brain barrier using focused ultrasound in mice. Ultrasound Med. Biol. 2007, 33:95-104.
4. de Geus-Oei L.F., van Krieken J.H., Aliredjo R.P., Krabbe P.F., Frielink C., Verhagen A.F., Boerman O.C., Oyen W.J. Biological correlates of FDG uptake in non-small cell lung cancer. Lung Cancer 2007, 55:79-87.
5. Engel J., Kuhl D.E., Phelps M.E. Patterns of human local cerebral glucose metabolism during epileptic seizures. Science 1982, 218:64-66.
6. Fan L., Liu Y., Ying H., Xue Y., Zhang Z., Wang P., Liu L., Zhang H. Increasing of blood-tumor barrier permeability through paracellular pathway by low-frequency ultrasound irradiation in vitro. J. Mol. Neurosci. 2011, 43:541-548.
7. Fox P., Ingham R., George M.S., Mayberg H., Ingham J., Roby J., Martin C., Jerabek P. Imaging human intra-cerebral connectivity by PET during TMS. Neuroreport 1997, 8:2787-2791.
8. 18F-2-fluoro-2-deoxy-d-glucose uptake by positron emission tomography in colorectal cancer. Dig. Dis. Sci. 2006, 51:2198-2205.
9. 18F-FDG kinetics in patients with traumatic brain injury. J. Nucl. Med. 2004, 45:775-783.
10. Huang S.C., Phelps M.E., Hoffman E.J., Sideris K., Selin C.J., Kuhl D.E. Noninvasive determination of local cerebral metabolic rate of glucose in man. Am. J. Physiol. 1980, 238:E69-E82.
11. 18F]fluoro-d-glucose transport and phosphorylation rates in myocardium using dual-tracer kinetic experiments. FEBS Lett. 1987, 216:128-132.
12. Hynynen K. Ultrasound for drug and gene delivery to the brain. Adv. Drug Deliv. Rev. 2008, 60:1209-1217.
13. 18)F-FDG uptake changes in rat brain. Med. Phys. 2013, 40:033501.
14. Kinoshita M., McDannold N., Jolesz F.A., Hynynen K. Noninvasive localized delivery of Herceptin to the mouse brain by MRI-guided focused ultrasound-induced blood-brain barrier disruption. Proc. Natl. Acad. Sci. U. S. A. 2006, 103:11719-11723.
15. Moore A.H., Osteen C.L., Chatziioannou A.F., Hovda D.A., Cherry S.R. Quantitative assessment of longitudinal metabolic changes in vivo after traumatic brain injury in the adult rat using FDG-microPET. J. Cereb. Blood Flow Metab. 2000, 20:1492-1501.
16. Pardridge W.M. Drug and gene delivery to the brain: the vascular route. Neuron 2002, 36:555-558.
17. Rougemont D., Baron J.C., Collard P., Bustany P., Comar D., Agid Y. Local cerebral glucose utilisation in treated and untreated patients with Parkinson's disease. J. Neurol. Neurosurg. Psychiatry 1984, 47:824-830.
18. Shang X., Wang P., Liu Y., Zhang Z., Xue Y. Mechanism of low-frequency ultrasound in opening blood-tumor barrier by tight junction. J. Mol. Neurosci. 2011, 43:364-369.
19. 18F-FDG, the ATLAS small animal PET scanner, and arterial blood sampling. J. Nucl. Med. 2004, 45:665-672.
20. Siebner H.R., Willoch F., Peller M., Auer C., Boecker H., Conrad B., Bartenstein P. Imaging brain activation induced by long trains of repetitive transcranial magnetic stimulation. Neuroreport 1998, 9:943-948.
21. Sokoloff L., Reivich M., Kennedy C., Rosiers M.H.D., Patlak C.S., Pettigrew K.D., Sakurada O., Shinohara M. The [14c] deoxyglucose method for the measurement of local cerebral glucose utilization: theory, procedure, and normal values in the conscious and anesthetized albino rat1. J. Neurochem. 1977, 28:897-916.
22. Wu F., Shao Z.Y., Zhai B.J., Zhao C.L., Shen D.M. Ultrasound reverses multidrug resistance in human cancer cells by altering gene expression of ABC transporter proteins and Bax protein. Ultrasound Med. Biol. 2011, 37:151-159.
23. Yang F.Y., Liu S.H., Ho F.M., Chang C.H. Effect of ultrasound contrast agent dose on the duration of focused-ultrasound-induced blood-brain barrier disruption. J. Acoust. Soc. Am. 2009, 126:3344-3349.
24. Yang F.Y., Horng S.C., Lin Y.S., Kao Y.H. Association between contrast-enhanced MR images and blood-brain barrier disruption following transcranial focused ultrasound. J. Magn. Reson. Imaging 2010, 32:593-599.
25. Yang F.Y., Wang H.E., Lin G.L., Teng M.C., Lin H.H., Wong T.T., Liu R.S. Micro-SPECT/CT-based pharmacokinetic analysis of 99mTc-diethylenetriaminepentaacetic acid in rats with blood-brain barrier disruption induced by focused ultrasound. J. Nucl. Med. 2011, 52:478-484.
26. Yang F.Y., Chen Y.W., Chou F.I., Yen S.H., Lin Y.L., Wong T.T. Boron neutron capture therapy for glioblastoma multiforme: enhanced drug delivery and antitumor effect following blood-brain barrier disruption induced by focused ultrasound. Future Oncol. 2012, 8:1361-1369.
27. Yang F.Y., Teng M.C., Lu M., Liang H.F., Lee Y.R., Yen C.C., Liang M.L., Wong T.T. Treating glioblastoma multiforme with selective high-dose liposomal doxorubicin chemotherapy induced by repeated focused ultrasound. Int. J. Nanomedicine 2012, 7:965-974.
28. Yang F.Y., Wong T.T., Teng M.C., Liu R.S., Lu M., Liang H.F., Wei M.C. Focused ultrasound and interleukin-4 receptor-targeted liposomal doxorubicin for enhanced targeted drug delivery and antitumor effect in glioblastoma multiforme. J. Control. Release 2012, 160:652-658.
29. Zhai B.J., Shao Z.Y., Zhao C.L., Hu K., Shen D.M., Wu F. Optimization of ultrasound-mediated in vitro reversal of multidrug resistance in human hepatocarcinoma cell line HepG2. Ultrasound Med. Biol. 2008, 34:1697-1702.