Metronidazole and hydroxymetronidazole central nervous system distribution: 1. Microdialysis assessment of brain extracellular fluid concentrations in patients with acute brain injury

Antimicrobial Agents and Chemotherapy

Volumn 58, Issue 2, 2014, Pages 1019-1023

  Frasca, Denis ^a,b,c   Dahyot Fizelier, Claire ^a,b,c   Adier, Christophe ^a,c   Mimoz, Olivier ^a,b,c   Debaene, Bertrand ^a,b,c   Couet, William ^a,b,c   Marchand, Sandrine ^a,b,c  

^a INSERM   (France)

^b UNIVERSITÉ DE POITIERS   (France)

^c POITIERS UNIVERSITY HOSPITAL   (France)

Author keywords

[No Author keywords available]

Indexed keywords

HYDROXYMETRONIDAZOLE; METRONIDAZOLE; UNCLASSIFIED DRUG;

ADULT; AGED; AREA UNDER THE CURVE; ARTICLE; BLOOD SAMPLING; BRAIN INJURY; CASE REPORT; DIALYSATE; DRUG DISTRIBUTION; EXTRACELLULAR FLUID; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; MALE; MICRODIALYSIS; MIDDLE AGED; PLASMA CONCENTRATION-TIME CURVE; PRIORITY JOURNAL;

AGED; ANTI-INFECTIVE AGENTS; AREA UNDER CURVE; BIOTRANSFORMATION; BLOOD-BRAIN BARRIER; BRAIN; BRAIN INJURIES; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; EXTRACELLULAR FLUID; HUMANS; MALE; METRONIDAZOLE; MICRODIALYSIS; MIDDLE AGED;

EID: 84893513808     PISSN: 00664804     EISSN: 10986596     Source Type: Journal    
DOI: 10.1128/AAC.01760-13     Document Type: Article

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