Fishing for ALK with immunohistochemistry may predict response to crizotinib

Tumori

Volumn 99, Issue 5, 2013, Pages

  Bavieri, Mario ^a   Tiseo, Marcello ^b   Lantuejoul, Sylvie ^b   McLeer Florin, Anne ^c   Lasagni, Anna ^a   Fantini, Riccardo ^a   Rossi, Giulio ^d  

^a UNIVERSITY OF MODENA AND REGGIO EMILIA   (Italy)

^b UNIVERSITY HOSPITAL OF PARMA   (Italy)

^c HÔPITAL MICHALLON   (France)

^d S MARIA NUOVA HOSPITAL   (Italy)

Author keywords

ALK; Crizotinib; FISH; IHC; NSCLC

Indexed keywords

EID: 84893498337     PISSN: 03008916     EISSN: 20382529     Source Type: Journal    
DOI: 10.1700/1377.15321     Document Type: Article

References (12)

1. Soda M, Choi YL, Enomoto M, Takada S, Yamashita Y, Ishikawa S, Fujiwara S, Watanabe H, Kurashina K, Hatanaka H, Bando M, Ohno S, Ishikawa Y, Aburatani H, Niki T, Sohara Y, Sugiyama Y, Mano H: Identification of the transforming EML4-ALK fusion gene in non-small-cell lung cancer. Nature, 448: 561-566, 2007.
2. Kwak EL, Bang YJ, Camidge DR, Shaw AT, Solomon B, Maki RG, Ou SH, Dezube BJ, Jänne PA, Costa DB, Varella-Garcia M, Kim WH, Lynch TJ, Fidias P, Stubbs H, Engelman JA, Sequist LV, Tan W, Gandhi L, Mino-Kenudson M, Wei GC, Shreeve SM, Ratain MJ, Settleman J, Christensen JG, Haber DA, Wilner K, Salgia R, Shapiro GI, Clark JW, Iafrate AJ: Anaplastic lymphoma kinase inhibition in non-small-cell lung cancer. N Engl J Med, 363: 1693-1703, 2010.
3. Tiseo M, Gelsomino F, Bartolotti M, Bordi P, Bersanelli M, Rossi G, Ardizzoni A: ALK as new target for the treatment of NSCLC. Expert Rev Anticancer Ther, 11: 1677-1687, 2011.
4. Murakami Y, Mitsudomi T, Yatabe Y: A screening method for the ALK fusion gene in NSCLC. Front Oncol, 2: 1-9, 2012.
5. McLeer-Florin A, Moro-Sibolot D, Melis A, Salameire D, Lefebvre C, Ceccaldi F, de Fraipont F, Brambilla E, Lantuejoul S: Dual IHC and FISH testing for ALK gene rearrangement in lung adenocarcinomas in a routine practice. A French study. J Thorac Oncol, 7: 348-354, 2012.
6. Park HS, Leeb JK, Kim DW, Kulig K, Kim TM, Lee SH, Jeon YK, Chung DH, Heo DS: Immunohistochemical screening for anaplastic lymphoma kinase (ALK) rearrangement in advanced non-small cell lung cancer patients. Lung Cancer, 77: 288-292, 2012.
7. Rodig SJ, Mino-Kenudson M, Dacic S, Yeap BY, Shaw A, Barletta JA, Stubbs H, Law K, Lindeman N, Mark E, Janne PA, Lynch T, Johnson BE, Iafrate AJ, Chirieac LR: Unique clinicopathologic features characterize ALK-rearranged lung adenocarcinoma in the western population. Clin Cancer Res, 15: 5216-5323, 2009.
8. Peled N, Palmer G, Hirsch FR, Wynes MW, Ilouze M, Varella-Garcia M, Soussan-Gutman L, Otto GA, Stephens PJ, Ross JS, Cronin MT, Lipson D, Miller VA: Next-generation sequencing identifies and immunuhistochemistry confirms a novel crizotinib-sensitive ALK rearrangement in a patient with metastatic non-small-cell lung cancer. J Thorac Oncol, 7: e14-e16, 2012.
9. Sun JM, Choi YL, Won JK, Hirsch FR, Ahn JS, Ahn MJ, Park K: A dramatic response to crizotinib in non-small-cell lung cancer patient with IHC-positive and FISH-negative ALK. J Thorac Oncol, 7: e36-e38, 2012.
10. Camidge DR, Theodoro M, Maxson DA, Skokan M, O'Brien T, Lu X, Doebele RC, Barón AE, Varella-Garcia M: Correlations between the percentage of tumor cells showing an anaplastic lymphoma kinase (ALK) gene rearrangement, ALK signal copy number, and response to crizotinib therapy in ALK fluorescence in situ hybridization-positive nonsmall cell lung cancer. Cancer, 118: 4486-4494, 2012.
11. Martinez P, Hernandez-Losa J, Montero MA, Cedrés S, Castellví J, Martinez-Marti A, Tallada N, Murtra-Garrell N, Navarro-Mendivill A, Rodriguez-Freixinos V, Canela M, Ramon y Cajal S, Felip E: Fluorescence in situ hybridization and immunohistochemistry as diagnostic methods for ALK positive non-small cell lung cancer patients. PLoS ONE, 8: e55261, 2013.
12. Conklin CM, Craddock KJ, Have C, Laskin J, Couture C, Ionescu DN: Immunohistochemistry is a reliable screening tool for identification of ALK rearrangement in non-smallcell lung carcinoma and is antibody dependent. J Thorac Oncol, 8: 45-51, 2013.