Advances in targeting the vacuolar proton-translocating ATPase (V-ATPase) for anti-fungal therapy

Frontiers in Pharmacology

Volumn 5 JAN, Issue , 2014, Pages

  Hayek, Summer R ^a   Lee, Samuel A ^a,b   Parra, Karlett J ^a  

^a UNIVERSITY OF NEW MEXICO SCHOOL OF MEDICINE   (United States)

^b NEW MEXICO VA HEALTH CARE SYSTEM   (United States)

Author keywords

Anti fungal target; C. albicans virulence; Fungal V ATPase; PH homeostasis; Vacuolar acidification; Vacuolar proton pump

Indexed keywords

ALEXIDINE DIHYDROCHLORIDE; BAFILOMYCIN; CONCANAMYCIN; DISULFIRAM; EBSELEN; FLUCONAZOLE; FUNGAL PROTEIN; PMA1P PROTEIN; PROTON TRANSPORTING ADENOSINE TRIPHOSPHATE SYNTHASE; PROTON TRANSPORTING ADENOSINE TRIPHOSPHATE SYNTHASE INHIBITOR; PYRROLE; TONZONIUM BROMIDE; UNCLASSIFIED DRUG;

ACIDIFICATION; ANTIFUNGAL ACTIVITY; CANDIDA ALBICANS; CANDIDIASIS; CELL FUNCTION; DRUG INHIBITION; DRUG TARGETING; ENZYME ACTIVITY; ENZYME MECHANISM; ENZYME REGULATION; FUNGAL VIRULENCE; GENETIC VARIABILITY; HUMAN; MYCOSIS; NONHUMAN; PROTEIN ANALYSIS; PROTEIN ASSEMBLY; PROTEIN QUATERNARY STRUCTURE; REVIEW; SACCHAROMYCES CEREVISIAE; SIGNAL TRANSDUCTION;

EID: 84893487618     PISSN: None     EISSN: 16639812     Source Type: Journal    
DOI: 10.3389/fphar.2014.00004     Document Type: Review

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