Micro-emulsion based emulgel: A novel topical drug delivery system

Asian Pacific Journal of Tropical Disease

Volumn 4, Issue S1, 2014, Pages

  Ashara, Kalpesh Chhotalal ^a   Paun, Jalpa S ^a   Soniwala, Moinuddin M ^a   Chavada, Jayant R ^a   Mori, Nitin Merubhai ^b  

^a B K Mody Government Pharmacy College   (India)

^b SAURASHTRA UNIVERSITY   (India)

Author keywords

Emulgel; Micro emulsion; Microemulgel; Topical drug delivery system

Indexed keywords

ARTICLE; CENTRIFUGATION; DRUG DELIVERY SYSTEM; DRUG PENETRATION; DRUG RELEASE; DRUG STABILITY; DRUG SYNTHESIS; EMULGEL; FUNCTIONAL ANATOMY; GEL; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; IN VITRO STUDY; MICROEMULSION; PH MEASUREMENT; PHYSICAL CHEMISTRY; PRIORITY JOURNAL; SKIN IRRITATION; THERMODYNAMICS; THERMOSTABILITY; TOPICAL TREATMENT; VISCOSITY; ZETA POTENTIAL;

EID: 84893434022     PISSN: 22221808     EISSN: None     Source Type: Journal    
DOI: 10.1016/S2222-1808(14)60411-4     Document Type: Article

References (39)

1. Walters KA Dermatological and transdermal formulation 2002, 323-327. CRC Press, Florida, 403.
2. Prajapati MK, Patel MR, Patel KR, Patel NM Emulgels: a novel approach to topical drug delivery. Int J Univ Pharm Bio Sci 2013, 2(1):134-148.
3. Sabale V, Vora S Formulation and evaluation of micro-emulsion-based hydrogel for topical delivery. Int J Pharm Investig 2013, 2:140-149.
4. Sharma DL, Seth AK, Shah N, Chauhan SP, Aundhia C Preparation and characterizaton of aceclofenac loaded topical emulgel. Pharmatutor Pharmacy Infopedia. [Online] [Accessed on 14th October, 2013]. http://www.pharmatutor.org/articles/preparation-characterizaton-aceclofenac-loaded-topical-emulgel.
5. Shah NV, Ghelani TK, Saini V, Joshi UT, Seth AK, Chauhan SP, et al. Develpoment and characterizaton of micro-emulsion based system of aceclofenac. Indo Am J Pharm Res 2011, 2(1):110-124.
6. Shah RR, Magdum CS, Patil SS, Niakwade NS Preparation and evaluation of aceclofenac topical micro-emulsion. Iran J Pharm Res 2010, 9(1):5-11.
7. Lawrence MJ, Rees GD Micro-emulsion based media as novel drug delivery systems. Adv Drug Deliv Rev 2012, 45(1):89-121.
8. Khullar R, Kumar D, Seth N, Saini S Formulation and evaluation of mefenamic acid emulgel for topical delivery. Saudi Pharm J 2012, 20:63-67.
9. Baibhav J, Gurpreet S, Rana AC, Seema S Development and characterization of clarithromycin emulgel for topical delivery. Int J Drug Dev Res 2012, 4(3):310-323.
10. Stanos SP Topical agents for the management of musculoskeletal pain. J Pain Symptom Manage 2007, 33:342-355.
11. Kanikkannan N, Kandimalla K, Lamba SS, Singh M Structure activity relationship of chemical penetration enhancers in transdermal drug delivery. Curr Med Chem 1999, 7:593-608.
12. Singh PB, Choudhury PK Penetration enhancers for transfer drug delivery of systemic agents. J Pharm Res 2007, 6:44-50.
13. US National Institute of Health Anatomy of the skin. Bethesda: US National Institute of Health. [Online] [Accessed on 21st August, 2013]. http://training.seer.cancer.gov/images/melanoma/skin.jpg.
14. Jain K, Deveda P, Vyas N, Chauhan J, Khambete H, Jain S Development of antifungal emulsion based gel for topical fungal infection. Int J Pharm Res Dev 2011, 3(2):18-25.
15. Ayub AC, Gomes AD, Lima MV, Vianna-Soares CD, Ferreira LA Topical delivery of fluconazole: in vitro skin penetration and permeation using emulsions as dosage forms. Drug Dev Ind Pharm 2007, 33(3):273-280.
16. InTech The skin 2012, InTech, Rijeka, Croatia, [Online], [Accessed on 22th August, 2013]. http://www.intechopen.com/books/recent-advances-in-novel-drug-carrier-systems/nanocarrier-systems-for-transdermal-drug-delivery.
17. Patel D, Chaudhary SA, Parmar B, Bhura N Transdermal drug delivery system: a review. Pharm Innovation 2012, 4(1):78-87.
18. Subramanian N, Ghosal SK, Moulik SP Enhanced in vitro percutaneous absorption and in vivo anti-inflammatory effect of a selective cyclo-oxygenase inhibitor using micro-emulsion. Drug Dev Ind Pharm 2008, 31:405-416.
19. Rao YS, Deepthi KS, Chowdary KP Micro-emulsions: a novel drug carrier system. Int J Drug Deliv Technol 2009, 1(2):39-41.
20. Lee EA, Balakrishnan P, Song CK, Choi JH, Noh GY, Park CG, et al. Micro-emulsion-based hydrogel formulation of itraconazole for topical delivery. J Pharm Investig 2010, 40:305-311.
21. Rashmi M, Garg R, Kumar S, Gupta GD Topical gel: a review. Canada: Official publication of Pharmainfo.net. [Online] [Accessed on 5th August, 2013]. http://www.pharmainfo.net/reviews/topical-gel-review.
22. Shah RR, Magdum GS, Wadkar KA, Naikwade NS Fluconazole topical micro-emulsion: preparation and evaluation. Res J Pharm Technol 2009, 2(2):353-357.
23. Bonacucina G, Cespi M, Palmieri GF Characterization and stability of emulsion gels based on acrylamide/sodium acryloyldimethyl taurate copolymer. AAPS PharmSciTech 2009, 10(2):368-375.
24. Benson HA Transdermal drug delivery: penetration enhancement techniques. Curr Drug Deliv 2005, 2:23-33.
25. Rutrer N Drug absorption through the skin: a mixed blessing. Arch Dis Child 1987, 62:220-221.
26. Zhang XL, Zhao R, Qian W Preparation of an emulgel for treatment of aphthous ulcer on the basis of carbomers. Chin Pharm J 1995, 30:417-418.
27. Swarbricks J Encyclopedia of pharmaceutical technology 2007, Taylor & Francis, Oxford. 3rd ed.
28. Mandal S, Mandal SD Design and development of carbamazepine mucoadhesive micro-emulsion for intranasal delivery: an ex vivo study. Int J Pharm Sci Rev Res 2010, 3(1):56-60.
29. Kalra R, Mulik RS, Badgujar L, Paradkar AR, Mahadik KR, Bodhankar SL, et al. Development and characterization of micro-emulsion formulations for transdermal delivery of aceclofenac: a research. Int J Drug Formulation Res 2010, 1(1):359-386.
30. Anjali C, Dash M, Chandrasekaran N, Mukherjee A Anti bacterial activity of sunflower oil micro-emulsion. Int J Pharm Pharm Sci 2010, 2:123-128.
31. Mandal S, Mandal SS Micro-emulsion drug delivery system: a platform form improving dissolution rate of poorly water soluble drug. Int J Pharm Sci Nanotechnol 2011, 3(4):1214-1219.
32. Mandal S, Mandal SS, Sawant KK Design and development of micro-emulsion drug delivery system of atorvastatin and study its intestinal permeability in rats. Int J Drug Deliv Technol 2010, 2:69-75.
33. Patel RB, Patel MR, Bhatt KK, Patel BG Formulation consideration and characterization of microemulsion drug delivery system for transnasal administration of carbamazepine. Bulletin of Faculty of Pharmacy Cairo university 2013, 51:243-253.
34. Kumar M, Pathak K, Misra A Formulation and characterization of nanoemulsion-based drug delivery system of risperidone. Drug Dev Ind Pharm 2009, 35:387-395.
35. Barakat N, Fouad E, Elmedany A Formulation design of indomethacin-loaded nanoemulsion for transdermal delivery. Pharm Anal Acta 2011, 10.4172/2153-2435.S2-002.
36. Bachhav YG, Patravale VB Formulation of meloxicam gel for topical application: in vitro and in vivo evaluation. Acta Pharm 2010, 60:153-163.
37. Charoenrein S, Tatirat O, Rengsutthi K, Thongngam M Effect of konjac glucomannan on syneresis, textural properties and the microstructure of frozen rice starch gels. Carbohydr Polym 2011, 83:291-296.
38. Sarkar BK, Patel R, Bhadoriya U Antimicrobial activity of some novel pyrazoline derivatives. J Adv Pharm Edu Res 2011, 1:243-250.
39. Sharma B, Sharma A, Arora S, Gupta S, Bishnoi M Formulation, optimization and evaluation of atorvastatin Calcium loaded micro-emulsion. J Pharm Drug Deliv Res 2012, 10.4172/2325-9604.1000109.