Membrane cholesterol removal changes mechanical properties of cells and induces secretion of a specific pool of lysosomes

PLoS ONE

Volumn 8, Issue 12, 2013, Pages

  Hissa, Barbara ^a   Pontes, Bruno ^b   Roma, Paula Magda S ^a   Alves, Ana Paula ^a   Rocha, Carolina D ^a   Valverde, Thalita M ^a   Aguiar, Pedro Henrique N ^a   Almeida, Fernando P ^b   Guimarães, Allan J ^c   Guatimosim, Cristina ^a   Silva, Aristóbolo M ^a   Fernandes, Maria C ^d   Andrews, Norma W ^d   Viana, Nathan B ^b   Mesquita, Oscar N ^a   Agero, Ubirajara ^a   Andrade, Luciana O ^a  

^a FEDERAL UNIVERSITY OF MINAS GERAIS   (Brazil)

^b FEDERAL UNIVERSITY OF RIO DE JANEIRO   (Brazil)

^c FLUMINENSE FEDERAL UNIVERSITY   (Brazil)

^d University of Maryland   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHOLESTEROL; METHYL BETA CYCLODEXTRIN; RHO FACTOR; SYNAPTOTAGMIN; SYNAPTOTAGMIN VII; UNCLASSIFIED DRUG;

ACTIN FILAMENT; ACTIN POLYMERIZATION; ANIMAL CELL; ARTICLE; CELL MEMBRANE; CONTROLLED STUDY; CYTOSKELETON; EMBRYO; EXOCYTOSIS; FIBROBLAST; LYSOSOME; MICROSCOPY; MOUSE; NONHUMAN; OPTICAL TWEEZERS; STRESS FIBER; SURFACE TENSION; YOUNG MODULUS;

ACTINS; ANIMALS; BETA-CYCLODEXTRINS; BICYCLO COMPOUNDS, HETEROCYCLIC; CELL LINE; CELL MEMBRANE; CHOLESTEROL; CYTOSKELETON; EXOCYTOSIS; FIBROBLASTS; GENE EXPRESSION; LYSOSOMES; MEMBRANE FLUIDITY; MICE; RHO GTP-BINDING PROTEINS; RNA, SMALL INTERFERING; SYNAPTOTAGMINS; THIAZOLIDINES;

EID: 84893414590     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0082988     Document Type: Article

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