-
1
-
-
0037451929
-
The epidemiology of sepsis in the united states from 1979 through 2000
-
Martin, G. S., D. M. Mannino, S. Eaton, and M. Moss. 2003. The epidemiology of sepsis in the United States from 1979 through 2000. N. Engl. J. Med. 348: 1546-1554.
-
(2003)
N. Engl. J. Med
, vol.348
, pp. 1546-1554
-
-
Martin, G.S.1
Mannino, D.M.2
Eaton, S.3
Moss, M.4
-
2
-
-
78049351610
-
The lingering consequences of sepsis: A hidden public health disaster?
-
Angus, D. C. 2010. The lingering consequences of sepsis: a hidden public health disaster? JAMA 304: 1833-1834.
-
(2010)
JAMA
, vol.304
, pp. 1833-1834
-
-
Angus, D.C.1
-
3
-
-
84875262757
-
The inflammatory response in sepsis
-
Bosmann, M., and P. A. Ward. 2013. The inflammatory response in sepsis. Trends Immunol. 34: 129-136.
-
(2013)
Trends Immunol
, Issue.34
, pp. 129-136
-
-
Bosmann, M.1
Ward, P.A.2
-
4
-
-
0037180768
-
The immunopathogenesis of sepsis
-
Cohen, J. 2002. The immunopathogenesis of sepsis. Nature 420: 885-891.
-
(2002)
Nature
, vol.420
, pp. 885-891
-
-
Cohen, J.1
-
5
-
-
84861706642
-
Septic shock evaluating another failed treatment
-
Wenzel, R. P., and M. B. Edmond. 2012. Septic shock -evaluating another failed treatment. N. Engl. J. Med. 366: 2122-2124.
-
(2012)
N. Engl. J. Med
, Issue.366
, pp. 2122-2124
-
-
Wenzel, R.P.1
Edmond, M.B.2
-
6
-
-
77954558483
-
Novel insights for systemic inflammation in sepsis and hemorrhage
-
Cai, B., E. A. Deitch, and L. Ulloa. 2010. Novel insights for systemic inflammation in sepsis and hemorrhage. Mediators Inflamm. 2010: 642462.
-
(2010)
Mediators Inflamm
, Issue.2010
, pp. 642462
-
-
Cai, B.1
Deitch, E.A.2
Ulloa, L.3
-
8
-
-
34247884612
-
The function of programmed cell death 1 and its ligands in regulating autoimmunity and infection
-
Sharpe, A. H., E. J. Wherry, R. Ahmed, and G. J. Freeman. 2007. The function of programmed cell death 1 and its ligands in regulating autoimmunity and infection. Nat. Immunol. 8: 239-245.
-
(2007)
Nat. Immunol
, vol.8
, pp. 239-245
-
-
Sharpe, A.H.1
Wherry, E.J.2
Ahmed, R.3
Freeman, G.J.4
-
9
-
-
42649125225
-
Pd-1 and its ligands in tolerance and immunity
-
Keir, M. E., M. J. Butte, G. J. Freeman, and A. H. Sharpe. 2008. PD-1 and its ligands in tolerance and immunity. Annu. Rev. Immunol. 26: 677-704.
-
(2008)
Annu. Rev. Immunol
, vol.26
, pp. 677-704
-
-
Keir, M.E.1
Butte, M.J.2
Freeman, G.J.3
Sharpe, A.H.4
-
10
-
-
32544459770
-
Restoring function in exhausted cd8 t cells during chronic viral infection
-
Barber, D. L., E. J. Wherry, D. Masopust, B. Zhu, J. P. Allison, A. H. Sharpe, G. J. Freeman, and R. Ahmed. 2006. Restoring function in exhausted CD8 T cells during chronic viral infection. Nature 439: 682-687.
-
(2006)
Nature
, vol.439
, pp. 682-687
-
-
Barber, D.1
Wherry, E.J.2
Masopust, D.3
Zhu, B.4
Allison, J.P.5
Sharpe, A.H.6
Freeman, G.J.7
Ahmed, R.8
-
11
-
-
84859158384
-
Targeting the pd-1/b7-h1 (pd-l1) pathway to activate anti-tumor immunity
-
Topalian, S. L., C. G. Drake, and D. M. Pardoll. 2012. Targeting the PD-1/B7-H1 (PD-L1) pathway to activate anti-tumor immunity. Curr. Opin. Immunol. 24: 207-212.
-
(2012)
Curr. Opin. Immunol
, vol.24
, pp. 207-212
-
-
Topalian, S.L.1
Drake, C.G.2
Pardoll, D.M.3
-
12
-
-
77953747963
-
The pd-1 pathway in tolerance and autoimmunity
-
Francisco, L. M., P. T. Sage, and A. H. Sharpe. 2010. The PD-1 pathway in tolerance and autoimmunity. Immunol. Rev. 236: 219-242.
-
(2010)
Immunol. Rev
, Issue.236
, pp. 219-242
-
-
Francisco, L.M.1
Sage, P.T.2
Sharpe, A.H.3
-
13
-
-
77953513733
-
Role of pd-1 in regulating acute infections
-
Brown, K. E., G. J. Freeman, E. J. Wherry, and A. H. Sharpe. 2010. Role of PD-1 in regulating acute infections. Curr. Opin. Immunol. 22: 397-401.
-
(2010)
Curr. Opin. Immunol
, Issue.22
, pp. 397-401
-
-
Brown, K.E.1
Freeman, G.J.2
Wherry, E.J.3
Sharpe, A.H.4
-
14
-
-
65549084772
-
Pd-1 expression by macrophages plays a pathologic role in altering microbial clearance and the innate inflammatory response to sepsis
-
Huang, X., F. Venet, Y. L. Wang, A. Lepape, Z. Yuan, Y. Chen, R. Swan, H. Kherouf, G. Monneret, C. S. Chung, and A. Ayala. 2009. PD-1 expression by macrophages plays a pathologic role in altering microbial clearance and the innate inflammatory response to sepsis. Proc. Natl. Acad. Sci. USA 106: 6303-6308.
-
(2009)
Proc. Natl. Acad. Sci. USA
, vol.106
, pp. 6303-6308
-
-
Huang, X.1
Venet, F.2
Wang, Y.L.3
Lepape, A.4
Yuan, Z.5
Chen, Y.6
Swan, R.7
Kherouf, H.8
Monneret, G.9
Chung, C.S.10
Ayala, A.11
-
15
-
-
1642306942
-
B7-h1 determines accumulation and deletion of intrahepatic cd8(+) t lymphocytes
-
Dong, H., G. Zhu, K. Tamada, D. B. Flies, J. M. van Deursen, and L. Chen. 2004. B7-H1 determines accumulation and deletion of intrahepatic CD8(+) T lymphocytes. Immunity 20: 327-336.
-
(2004)
Immunity
, vol.20
, pp. 327-336
-
-
Dong, H.1
Zhu, G.2
Tamada, K.3
Flies, D.B.4
Van Deursen, J.M.5
Chen, L.6
-
16
-
-
0033180181
-
Development of lupus-like autoimmune diseases by disruption of the pd-1 gene encoding an itim motif-carrying immunoreceptor
-
Nishimura, H., M. Nose, H. Hiai, N. Minato, and T. Honjo. 1999. Development of lupus-like autoimmune diseases by disruption of the PD-1 gene encoding an ITIM motif-carrying immunoreceptor. Immunity 11: 141-151.
-
(1999)
Immunity
, vol.11
, pp. 141-151
-
-
Nishimura, H.1
Nose, M.2
Hiai, H.3
Minato, N.4
Honjo, T.5
-
17
-
-
0031128235
-
Factors responsible for peritoneal granulocyte apoptosis during sepsis
-
Ayala, A., S. M. Karr, T. A. Evans, and I. H. Chaudry. 1997. Factors responsible for peritoneal granulocyte apoptosis during sepsis. J. Surg. Res. 69: 67-75.
-
(1997)
J. Surg. Res
, vol.69
, pp. 67-75
-
-
Ayala, A.1
Karr, S.M.2
Evans, T.A.3
Chaudry, I.H.4
-
18
-
-
0033174324
-
Immunopathologic responses to non-lethal sepsis
-
Ebong, S. J., D. R. Call, G. Bolgos, D. E. Newcomb, J. I. Granger, M. O'Reilly, and D. G. Remick. 1999. Immunopathologic responses to non-lethal sepsis. Shock 12: 118-126.
-
(1999)
Shock
, vol.12
, pp. 118-126
-
-
Ebong, S.J.1
Call, D.R.2
Bolgos, G.3
Newcomb, D.E.4
Granger, J.I.5
O'Reilly, M.6
Remick, D.G.7
-
19
-
-
78650630315
-
Early enhanced local neutrophil recruitment in peritonitis-induced sepsis improves bacterial clearance and survival
-
Craciun, F. L., E. R. Schuller, and D. G. Remick. 2010. Early enhanced local neutrophil recruitment in peritonitis-induced sepsis improves bacterial clearance and survival. J. Immunol. 185: 6930-6938.
-
(2010)
J. Immunol
, Issue.185
, pp. 6930-6938
-
-
Craciun, F.L.1
Schuller, E.R.2
Remick, D.G.3
-
20
-
-
84857792409
-
Sepsis, thrombosis and organ dysfunction
-
Semeraro, N., C. T. Ammollo, F. Semeraro, and M. Colucci. 2012. Sepsis, thrombosis and organ dysfunction. Thromb. Res. 129: 290-295.
-
(2012)
Thromb. Res
, Issue.129
, pp. 290-295
-
-
Semeraro, N.1
Ammollo, C.T.2
Semeraro, F.3
Colucci, M.4
-
21
-
-
0035338993
-
Sepsis-induced apoptosis causes progressive profound depletion of b and cd4+ t lymphocytes in humans
-
Hotchkiss, R. S., K. W. Tinsley, P. E. Swanson, R. E. Schmieg, Jr., J. J. Hui, K. C. Chang, D. F. Osborne, B. D. Freeman, J. P. Cobb, T. G. Buchman, and I. E. Karl. 2001. Sepsis-induced apoptosis causes progressive profound depletion of B and CD4+ T lymphocytes in humans. J. Immunol. 166: 6952-6963.
-
(2001)
J. Immunol
, vol.166
, pp. 6952-6963
-
-
Hotchkiss, R.S.1
Tinsley, K.W.2
Swanson, P.E.3
Schmieg Jr., R.E.4
Hui, J.J.5
Chang, K.C.6
Osborne, D.F.7
Freeman, B.D.8
Cobb, J.P.9
Buchman, T.G.10
Karl, I.E.11
-
23
-
-
0037012470
-
Inhibition of intestinal epithelial apoptosis and survival in a murine model of pneumonia-induced sepsis
-
Coopersmith, C. M., P. E. Stromberg, W. M. Dunne, C. G. Davis, D. M. Amiot, II, T. G. Buchman, I. E. Karl, and R. S. Hotchkiss. 2002. Inhibition of intestinal epithelial apoptosis and survival in a murine model of pneumonia-induced sepsis. JAMA 287: 1716-1721.
-
(2002)
JAMA
, vol.287
, pp. 1716-1721
-
-
Coopersmith, C.M.1
Stromberg, P.E.2
Dunne, W.M.3
Davis, C.G.4
Amiot, D.M.5
Buchman II, T.G.6
Karl, I.E.7
Hotchkiss, R.S.8
-
24
-
-
33750288937
-
Apoptosis and caspases regulate death and inflammation in sepsis
-
Hotchkiss, R. S., and D. W. Nicholson. 2006. Apoptosis and caspases regulate death and inflammation in sepsis. Nat. Rev. Immunol. 6: 813-822.
-
(2006)
Nat. Rev. Immunol
, vol.6
, pp. 813-822
-
-
Hotchkiss, R.S.1
Nicholson, D.W.2
-
25
-
-
33947277195
-
Role of protein c in renal dysfunction after polymicrobial sepsis
-
Gupta, A., D. T. Berg, B. Gerlitz, G. R. Sharma, S. Syed, M. A. Richardson, G. Sandusky, J. G. Heuer, E. J. Galbreath, and B. W. Grinnell. 2007. Role of protein C in renal dysfunction after polymicrobial sepsis. J. Am. Soc. Nephrol. 18: 860-867.
-
(2007)
J. Am. Soc. Nephrol
, Issue.18
, pp. 860-867
-
-
Gupta, A.1
Berg, D.T.2
Gerlitz, B.3
Sharma, G.R.4
Syed, S.5
Richardson, M.A.6
Sandusky, G.7
Heuer, J.G.8
Galbreath, E.J.9
Grinnell, B.W.10
-
26
-
-
0030011909
-
Toward a theory regarding the pathogenesis of the systemic inflammatory response syndrome: What we do and do not know about cytokine regulation
-
Bone, R. C. 1996. Toward a theory regarding the pathogenesis of the systemic inflammatory response syndrome: what we do and do not know about cytokine regulation. Crit. Care Med. 24: 163-172.
-
(1996)
Crit. Care Med
, vol.24
, pp. 163-172
-
-
Bone, R.C.1
-
27
-
-
84867045163
-
Role of the pd-1 pathway in the immune response
-
Riella, L. V., A. M. Paterson, A. H. Sharpe, and A. Chandraker. 2012. Role of the PD-1 pathway in the immune response. Am. J. Transplant. 12: 2575-2587.
-
(2012)
Am. J. Transplant
, Issue.12
, pp. 2575-2587
-
-
Riella, L.V.1
Paterson, A.M.2
Sharpe, A.H.3
Chandraker, A.4
-
28
-
-
84887006158
-
Kupffer cells potentiate liver sinusoidal endothelial cell injury in sepsis by ligating programmed cell death ligand-1
-
Hutchins, N. A., F. Wang, Y. Wang, C. S. Chung, and A. Ayala. 2013. Kupffer cells potentiate liver sinusoidal endothelial cell injury in sepsis by ligating programmed cell death ligand-1. J. Leukoc. Biol. 94: 963-970.
-
(2013)
J. Leukoc. Biol
, Issue.94
, pp. 963-970
-
-
Hutchins, N.A.1
Wang, F.2
Wang, Y.3
Chung, C.S.4
Ayala, A.5
-
29
-
-
65249098310
-
The diversity of costimulatory and inhibitory receptor pathways and the regulation of antiviral t cell responses
-
Crawford, A., and E. J. Wherry. 2009. The diversity of costimulatory and inhibitory receptor pathways and the regulation of antiviral T cell responses. Curr. Opin. Immunol. 21: 179-186.
-
(2009)
Curr. Opin. Immunol
, vol.21
, pp. 179-186
-
-
Crawford, A.1
Wherry, E.J.2
-
30
-
-
70350743827
-
Pd-1 and ctla-4 inhibitory cosignaling pathways in hiv infection and the potential for therapeutic intervention
-
Kaufmann, D. E., and B. D. Walker. 2009. PD-1 and CTLA-4 inhibitory cosignaling pathways in HIV infection and the potential for therapeutic intervention. J. Immunol. 182: 5891-5897.
-
(2009)
J. Immunol
, vol.182
, pp. 5891-5897
-
-
Kaufmann, D.E.1
Walker, B.D.2
-
31
-
-
0037111483
-
Expression of programmed death 1 ligands by murine t cells and apc
-
Yamazaki, T., H. Akiba, H. Iwai, H. Matsuda, M. Aoki, Y. Tanno, T. Shin, H. Tsuchiya, D. M. Pardoll, K. Okumura, et al. 2002. Expression of programmed death 1 ligands by murine T cells and APC. J. Immunol. 169: 5538-5545.
-
(2002)
J. Immunol
, vol.169
, pp. 5538-5545
-
-
Yamazaki, T.1
Akiba, H.2
Iwai, H.3
Matsuda, H.4
Aoki, M.5
Tanno, Y.6
Shin, T.7
Tsuchiya, H.8
Pardoll, D.M.9
Okumura, K.10
-
32
-
-
84861096769
-
Predictors of survival in sepsis: What is the best inflammatory marker to measure?
-
Lichtenstern, C., T. Brenner, H. J. Bardenheuer, and M. A. Weigand. 2012. Predictors of survival in sepsis: what is the best inflammatory marker to measure? Curr. Opin. Infect. Dis. 25: 328-336.
-
(2012)
Curr. Opin. Infect. Dis
, vol.25
, pp. 328-336
-
-
Lichtenstern, C.1
Brenner, T.2
Bardenheuer, H.J.3
Weigand, M.A.4
-
33
-
-
84856381402
-
A combined score of pro-And anti-inflammatory interleukins improves mortality prediction in severe sepsis
-
Andaluz-Ojeda, D., F. Bobillo, V. Iglesias, R. Almansa, L. Rico, F. Gandía, S. Resino, E. Tamayo, R. O. de Lejarazu, and J. F. Bermejo-Martin. 2012. A combined score of pro-And anti-inflammatory interleukins improves mortality prediction in severe sepsis. Cytokine 57: 332-336.
-
(2012)
Cytokine
, vol.57
, pp. 332-336
-
-
Andaluz-Ojeda, D.1
Bobillo, F.2
Iglesias, V.3
Almansa, R.4
Rico, L.5
Gandía, F.6
Resino, S.7
Tamayo, E.8
De Lejarazu, R.O.9
Bermejo-Martin, J.F.10
-
34
-
-
78650835112
-
Multiplex cytokine profiling in patients with sepsis
-
Mera, S., D. Tatulescu, C. Cismaru, C. Bondor, A. Slavcovici, V. Zanc, D. Carstina, and M. Oltean. 2011. Multiplex cytokine profiling in patients with sepsis. APMIS 119: 155-163.
-
(2011)
APMIS
, vol.119
, pp. 155-163
-
-
Mera, S.1
Tatulescu, D.2
Cismaru, C.3
Bondor, C.4
Slavcovici, A.5
Zanc, V.6
Carstina, D.7
Oltean, M.8
-
35
-
-
8544262221
-
Efficacy and safety of the monoclonal anti-tumor necrosis factor antibody f(ab9)2 fragment afelimomab in patients with severe sepsis and elevated interleukin-6 levels
-
Monoclonal Anti-TNF: a Randomized Controlled Sepsis Study Investigators
-
Panacek, E. A., J. C. Marshall, T. E. Albertson, D. H. Johnson, S. Johnson, R. D. MacArthur, M. Miller, W. T. Barchuk, S. Fischkoff, M. Kaul, et al; Monoclonal Anti-TNF: a Randomized Controlled Sepsis Study Investigators. 2004. Efficacy and safety of the monoclonal anti-tumor necrosis factor antibody F(ab9)2 fragment afelimomab in patients with severe sepsis and elevated interleukin-6 levels. Crit. Care Med. 32: 2173-2182.
-
(2004)
Crit. Care Med
, vol.32
, pp. 2173-2182
-
-
Panacek, E.A.1
Marshall, J.C.2
Albertson, T.E.3
Johnson, D.H.4
Johnson, S.5
MacArthur, R.D.6
Miller, M.7
Barchuk, W.T.8
Fischkoff, S.9
Kaul, M.10
-
36
-
-
34247623669
-
The diagnostic value of c-reactive protein, interleukin-8, and monocyte chemotactic protein in risk stratification of febrile neutropenic children with hematologic malignancies
-
El-Maghraby, S. M., M. M. Moneer, M. M. Ismail, L. M. Shalaby, and H. A. El-Mahallawy. 2007. The diagnostic value of C-reactive protein, interleukin-8, and monocyte chemotactic protein in risk stratification of febrile neutropenic children with hematologic malignancies. J. Pediatr. Hematol. Oncol. 29: 131-136.
-
(2007)
J. Pediatr. Hematol. Oncol
, vol.29
, pp. 131-136
-
-
El-Maghraby, S.M.1
Moneer, M.M.2
Ismail, M.M.3
Shalaby, L.M.4
El-Mahallawy, H.A.5
-
37
-
-
34249318067
-
Cytokine profiles as markers of disease severity in sepsis: A multiplex analysis
-
Bozza, F. A., J. I. Salluh, A. M. Japiassu, M. Soares, E. F. Assis, R. N. Gomes, M. T. Bozza, H. C. Castro-Faria-Neto, and P. T. Bozza. 2007. Cytokine profiles as markers of disease severity in sepsis: a multiplex analysis. Crit. Care 11: R49.
-
(2007)
Crit. Care
, vol.11
-
-
Bozza, F.A.1
Salluh, J.I.2
Japiassu, A.M.3
Soares, M.4
Assis, E.F.5
Gomes, R.N.6
Bozza, M.T.7
Castro-Faria-Neto, H.C.8
Bozza, P.T.9
-
38
-
-
33747368257
-
Evaluation of serum c-reactive protein, procalcitonin, tumor necrosis factor alpha, and interleukin-10 levels as diagnostic and prognostic parameters in patients with community-Acquired sepsis, severe sepsis, and septic shock
-
Heper, Y., E. H. Akalin, R. Mistik, S. Akgoz, O. Tore, G. Goral, B. Oral, F. Budak, and S. Helvaci. 2006. Evaluation of serum C-reactive protein, procalcitonin, tumor necrosis factor alpha, and interleukin-10 levels as diagnostic and prognostic parameters in patients with community-Acquired sepsis, severe sepsis, and septic shock. Eur. J. Clin. Microbiol. Infect. Dis. 25: 481-491.
-
(2006)
Eur. J. Clin. Microbiol. Infect. Dis
, vol.25
, pp. 481-491
-
-
Heper, Y.1
Akalin, E.H.2
Silasi-Mansat, R.3
Tore, O.4
Goral, G.5
Oral, B.6
Budak, F.7
Helvaci, S.8
-
40
-
-
1542313883
-
Fcgammariib balances efficient pathogen clearance and the cytokine-mediated consequences of sepsis
-
Clatworthy, M. R., and K. G. Smith. 2004. FcgammaRIIb balances efficient pathogen clearance and the cytokine-mediated consequences of sepsis. J. Exp. Med. 199: 717-723.
-
(2004)
J. Exp. Med
, vol.199
, pp. 717-723
-
-
Clatworthy, M.R.1
Smith, K.G.2
|