메뉴 건너뛰기




Volumn 35, Issue 2, 2014, Pages 272-281

Heat shock factor 1 accelerates hepatocellular carcinoma development by activating nuclear factor-κB/mitogen-activated protein kinase

Author keywords

[No Author keywords available]

Indexed keywords

BAG 3 PROTEIN; CARRIER PROTEIN; EPIDERMAL GROWTH FACTOR; HEAT SHOCK TRANSCRIPTION FACTOR 1; I KAPPA B KINASE GAMMA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE; SHORT HAIRPIN RNA; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

EID: 84893349967     PISSN: 01433334     EISSN: 14602180     Source Type: Journal    
DOI: 10.1093/carcin/bgt343     Document Type: Article
Times cited : (34)

References (43)
  • 1
    • 84860287080 scopus 로고    scopus 로고
    • Epidemiology of viral hepatitis and hepatocellular carcinoma
    • El-Serag,H.B. (2012) Epidemiology of viral hepatitis and hepatocellular carcinoma. Gastroenterology, 142, 1264-1273.e1.
    • (2012) Gastroenterology , vol.142
    • El-Serag, H.B.1
  • 2
    • 57749189578 scopus 로고    scopus 로고
    • Efficacy and safety of sorafenib in patients in the Asia-Pacific region with advanced hepatocellular carcinoma: a phase III randomised, double-blind, placebo-controlled trial
    • Cheng,A.L. et al. (2009) Efficacy and safety of sorafenib in patients in the Asia-Pacific region with advanced hepatocellular carcinoma: a phase III randomised, double-blind, placebo-controlled trial. Lancet Oncol., 10, 25-34.
    • (2009) Lancet Oncol. , vol.10 , pp. 25-34
    • Cheng, A.L.1
  • 3
    • 79957494402 scopus 로고    scopus 로고
    • Strategies for hepatocellular carcinoma therapy and diagnostics: lessons learned from high throughput and profiling approaches
    • Breuhahn,K. et al. (2011) Strategies for hepatocellular carcinoma therapy and diagnostics: lessons learned from high throughput and profiling approaches. Hepatology, 53, 2112-2121.
    • (2011) Hepatology , vol.53 , pp. 2112-2121
    • Breuhahn, K.1
  • 4
    • 17744372861 scopus 로고    scopus 로고
    • Roles of the heat shock transcription factors in regulation of the heat shock response and beyond
    • Pirkkala,L. et al. (2001) Roles of the heat shock transcription factors in regulation of the heat shock response and beyond. FASEB J., 15, 1118-1131.
    • (2001) FASEB J. , vol.15 , pp. 1118-1131
    • Pirkkala, L.1
  • 5
    • 0025755922 scopus 로고
    • Heat shock factor and the heat shock response
    • Sorger,P.K. (1991) Heat shock factor and the heat shock response. Cell, 65, 363-366.
    • (1991) Cell , vol.65 , pp. 363-366
    • Sorger, P.K.1
  • 6
    • 78049440475 scopus 로고    scopus 로고
    • Chromatin landscape dictates HSF binding to target DNA elements
    • Guertin,M.J. et al. (2010) Chromatin landscape dictates HSF binding to target DNA elements. PLoS Genet., 6, e1001114.
    • (2010) PLoS Genet. , vol.6
    • Guertin, M.J.1
  • 7
    • 84864585171 scopus 로고    scopus 로고
    • HSF1 drives a transcriptional program distinct from heat shock to support highly malignant human cancers
    • Mendillo,M.L. et al. (2012) HSF1 drives a transcriptional program distinct from heat shock to support highly malignant human cancers. Cell, 150, 549-562.
    • (2012) Cell , vol.150 , pp. 549-562
    • Mendillo, M.L.1
  • 8
    • 33751092252 scopus 로고    scopus 로고
    • Genome-wide analysis of human HSF1 signaling reveals a transcriptional program linked to cellular adaptation and survival
    • Page,T.J. et al. (2006) Genome-wide analysis of human HSF1 signaling reveals a transcriptional program linked to cellular adaptation and survival. Mol. Biosyst., 2, 627-639.
    • (2006) Mol. Biosyst. , vol.2 , pp. 627-639
    • Page, T.J.1
  • 9
    • 34548658230 scopus 로고    scopus 로고
    • Heat shock factor 1 is a powerful multifaceted modifier of carcinogenesis
    • Dai,C. et al. (2007) Heat shock factor 1 is a powerful multifaceted modifier of carcinogenesis. Cell, 130, 1005-1018.
    • (2007) Cell , vol.130 , pp. 1005-1018
    • Dai, C.1
  • 10
    • 33750212109 scopus 로고    scopus 로고
    • A novel HSF1-mediated death pathway that is suppressed by heat shock proteins
    • Hayashida,N. et al. (2006) A novel HSF1-mediated death pathway that is suppressed by heat shock proteins. EMBO J., 25, 4773-4783.
    • (2006) EMBO J. , vol.25 , pp. 4773-4783
    • Hayashida, N.1
  • 11
    • 36348938843 scopus 로고    scopus 로고
    • Heat shock factor 1 attenuates 4-hydroxynonenalmediated apoptosis: critical role for heat shock protein 70 induction and stabilization of Bcl-XL
    • Jacobs,A.T. et al. (2007) Heat shock factor 1 attenuates 4-hydroxynonenalmediated apoptosis: critical role for heat shock protein 70 induction and stabilization of Bcl-XL. J. Biol. Chem., 282, 33412-33420.
    • (2007) J. Biol. Chem. , vol.282 , pp. 33412-33420
    • Jacobs, A.T.1
  • 12
    • 30844456876 scopus 로고    scopus 로고
    • Spermatocyte-specific expression of constitutively active heat shock factor 1 induces HSP70i-resistant apoptosis in male germ cells
    • Vydra,N. et al. (2006) Spermatocyte-specific expression of constitutively active heat shock factor 1 induces HSP70i-resistant apoptosis in male germ cells. Cell Death Differ., 13, 212-222.
    • (2006) Cell Death Differ. , vol.13 , pp. 212-222
    • Vydra, N.1
  • 13
    • 84855457952 scopus 로고    scopus 로고
    • Hsp90 molecular chaperone inhibitors: are we there yet?
    • Neckers,L. et al. (2012) Hsp90 molecular chaperone inhibitors: are we there yet? Clin. Cancer Res., 18, 64-76.
    • (2012) Clin. Cancer Res. , vol.18 , pp. 64-76
    • Neckers, L.1
  • 14
    • 79960337453 scopus 로고    scopus 로고
    • Heat shock proteins in oncology: diagnostic biomarkers or therapeutic targets?
    • Khalil,A.A. et al. (2011) Heat shock proteins in oncology: diagnostic biomarkers or therapeutic targets? Biochim. Biophys. Acta, 1816, 89-104.
    • (2011) Biochim. Biophys. Acta , vol.1816 , pp. 89-104
    • Khalil, A.A.1
  • 15
    • 0037223571 scopus 로고    scopus 로고
    • Expression profiling in multistage hepatocarcinogenesis: identification of HSP70 as a molecular marker of early hepatocellular carcinoma
    • Chuma,M. et al. (2003) Expression profiling in multistage hepatocarcinogenesis: identification of HSP70 as a molecular marker of early hepatocellular carcinoma. Hepatology, 37, 198-207.
    • (2003) Hepatology , vol.37 , pp. 198-207
    • Chuma, M.1
  • 16
    • 0141545042 scopus 로고    scopus 로고
    • The tumor-selective over-expression of the human Hsp70 gene is attributed to the aberrant controls at both initiation and elongation levels of transcription
    • Cai,L. et al. (2003) The tumor-selective over-expression of the human Hsp70 gene is attributed to the aberrant controls at both initiation and elongation levels of transcription. Cell Res., 13, 93-109.
    • (2003) Cell Res. , vol.13 , pp. 93-109
    • Cai, L.1
  • 17
    • 34547616810 scopus 로고    scopus 로고
    • Selective suppression of lymphomas by functional loss of Hsf1 in a p53-deficient mouse model for spontaneous tumors
    • Min,J.N. et al. (2007) Selective suppression of lymphomas by functional loss of Hsf1 in a p53-deficient mouse model for spontaneous tumors. Oncogene, 26, 5086-5097.
    • (2007) Oncogene , vol.26 , pp. 5086-5097
    • Min, J.N.1
  • 18
    • 81055141345 scopus 로고    scopus 로고
    • High levels of nuclear heat-shock factor 1 (HSF1) are associated with poor prognosis in breast cancer
    • Santagata,S. et al. (2011) High levels of nuclear heat-shock factor 1 (HSF1) are associated with poor prognosis in breast cancer. Proc. Natl Acad. Sci. USA, 108, 18378-18383.
    • (2011) Proc. Natl Acad. Sci. USA , vol.108 , pp. 18378-18383
    • Santagata, S.1
  • 19
    • 79957931628 scopus 로고    scopus 로고
    • Prosurvival role of heat shock factor 1 in the pathogenesis of pancreatobiliary tumors
    • Dudeja,V. et al. (2011) Prosurvival role of heat shock factor 1 in the pathogenesis of pancreatobiliary tumors. Am. J. Physiol. Gastrointest. Liver Physiol., 300, G948-G955.
    • (2011) Am. J. Physiol. Gastrointest. Liver Physiol. , vol.300
    • Dudeja, V.1
  • 20
    • 0033899869 scopus 로고    scopus 로고
    • A novel association between the human heat shock transcription factor 1 (HSF1) and prostate adenocarcinoma
    • Hoang,A.T. et al. (2000) A novel association between the human heat shock transcription factor 1 (HSF1) and prostate adenocarcinoma. Am. J. Pathol., 156, 857-864.
    • (2000) Am. J. Pathol. , vol.156 , pp. 857-864
    • Hoang, A.T.1
  • 21
    • 84455163098 scopus 로고    scopus 로고
    • State of heat shock factor 1 expression as a putative diagnostic marker for oral squamous cell carcinoma
    • Ishiwata,J. et al. (2012) State of heat shock factor 1 expression as a putative diagnostic marker for oral squamous cell carcinoma. Int. J. Oncol., 40, 47-52.
    • (2012) Int. J. Oncol. , vol.40 , pp. 47-52
    • Ishiwata, J.1
  • 22
    • 61949171989 scopus 로고    scopus 로고
    • Pathologic diagnosis of early hepatocellular carcinoma: a report of the international consensus group for hepatocellular neoplasia
    • Kojiro,M. et al. (2009) Pathologic diagnosis of early hepatocellular carcinoma: a report of the international consensus group for hepatocellular neoplasia. Hepatology, 49, 658-664.
    • (2009) Hepatology , vol.49 , pp. 658-664
    • Kojiro, M.1
  • 23
    • 34247602670 scopus 로고    scopus 로고
    • Survival and apoptosis: a dysregulated balance in liver cancer
    • Fabregat,I. et al. (2007) Survival and apoptosis: a dysregulated balance in liver cancer. Liver Int., 27, 155-162.
    • (2007) Liver Int. , vol.27 , pp. 155-162
    • Fabregat, I.1
  • 24
    • 79959535966 scopus 로고    scopus 로고
    • Apoptosis signal-regulating kinase 1 inhibits hepatocarcinogenesis by controlling the tumor-suppressing function of stress-activated mitogen-activated protein kinase
    • Nakagawa,H. et al. (2011) Apoptosis signal-regulating kinase 1 inhibits hepatocarcinogenesis by controlling the tumor-suppressing function of stress-activated mitogen-activated protein kinase. Hepatology, 54, 185-195.
    • (2011) Hepatology , vol.54 , pp. 185-195
    • Nakagawa, H.1
  • 25
    • 54249125424 scopus 로고    scopus 로고
    • NF-kappaB signaling, liver disease and hepatoprotective agents
    • Sun,B. et al. (2008) NF-kappaB signaling, liver disease and hepatoprotective agents. Oncogene, 27, 6228-6244.
    • (2008) Oncogene , vol.27 , pp. 6228-6244
    • Sun, B.1
  • 26
    • 21244472975 scopus 로고    scopus 로고
    • IKKbeta couples hepatocyte death to cytokinedriven compensatory proliferation that promotes chemical hepatocarcinogenesis
    • Maeda,S. et al. (2005) IKKbeta couples hepatocyte death to cytokinedriven compensatory proliferation that promotes chemical hepatocarcinogenesis. Cell, 121, 977-990.
    • (2005) Cell , vol.121 , pp. 977-990
    • Maeda, S.1
  • 27
    • 27244457769 scopus 로고    scopus 로고
    • Raf: a strategic target for therapeutic development against cancer
    • Beeram,M. et al. (2005) Raf: a strategic target for therapeutic development against cancer. J. Clin. Oncol., 23, 6771-6790.
    • (2005) J. Clin. Oncol. , vol.23 , pp. 6771-6790
    • Beeram, M.1
  • 28
    • 77956627711 scopus 로고    scopus 로고
    • The role of signaling pathways in the development and treatment of hepatocellular carcinoma
    • Whittaker,S. et al. (2010) The role of signaling pathways in the development and treatment of hepatocellular carcinoma. Oncogene, 29, 4989-5005.
    • (2010) Oncogene , vol.29 , pp. 4989-5005
    • Whittaker, S.1
  • 29
    • 0043133760 scopus 로고    scopus 로고
    • Activation of heat shock genes is not necessary for protection by heat shock transcription factor 1 against cell death due to a single exposure to high temperatures
    • Inouye,S. et al. (2003) Activation of heat shock genes is not necessary for protection by heat shock transcription factor 1 against cell death due to a single exposure to high temperatures. Mol. Cell. Biol., 23, 5882-5895.
    • (2003) Mol. Cell. Biol. , vol.23 , pp. 5882-5895
    • Inouye, S.1
  • 30
    • 4644271628 scopus 로고    scopus 로고
    • Overexpression of cortactin is involved in motility and metastasis of hepatocellular carcinoma
    • Chuma,M. et al. (2004) Overexpression of cortactin is involved in motility and metastasis of hepatocellular carcinoma. J. Hepatol., 41, 629-636.
    • (2004) J. Hepatol. , vol.41 , pp. 629-636
    • Chuma, M.1
  • 31
    • 33746651189 scopus 로고    scopus 로고
    • Heat shock transcription factor (HSF1) plays a critical role in cell migration via maintaining MAP kinase signaling
    • O'Callaghan-Sunol,C. et al. (2006) Heat shock transcription factor (HSF1) plays a critical role in cell migration via maintaining MAP kinase signaling. Cell Cycle, 5, 1431-1437.
    • (2006) Cell Cycle , vol.5 , pp. 1431-1437
    • O'Callaghan-Sunol, C.1
  • 32
    • 0034048115 scopus 로고    scopus 로고
    • LPS-induced liver injury in D-galactosaminesensitized mice requires secreted TNF-alpha and the TNF-p55 receptor
    • Nowak,M. et al. (2000) LPS-induced liver injury in D-galactosaminesensitized mice requires secreted TNF-alpha and the TNF-p55 receptor. Am. J. Physiol. Regul. Integr. Comp. Physiol., 278, R1202-R1209.
    • (2000) Am. J. Physiol. Regul. Integr. Comp. Physiol. , vol.278
    • Nowak, M.1
  • 33
    • 77952112425 scopus 로고    scopus 로고
    • IKK{gamma} protein is a target of BAG3 regulatory activity in human tumor growth
    • Ammirante,M. et al. (2010) IKK{gamma} protein is a target of BAG3 regulatory activity in human tumor growth. Proc. Natl Acad. Sci. USA, 107, 7497-7502.
    • (2010) Proc. Natl Acad. Sci. USA , vol.107 , pp. 7497-7502
    • Ammirante, M.1
  • 34
    • 77956929098 scopus 로고    scopus 로고
    • Heat-shock transcription factor HSF1 has a critical role in human epidermal growth factor receptor-2-induced cellular transformation and tumorigenesis
    • Meng,L. et al. (2010) Heat-shock transcription factor HSF1 has a critical role in human epidermal growth factor receptor-2-induced cellular transformation and tumorigenesis. Oncogene, 29, 5204-5213.
    • (2010) Oncogene , vol.29 , pp. 5204-5213
    • Meng, L.1
  • 35
    • 34548785473 scopus 로고    scopus 로고
    • Non-oncogene addiction and the stress phenotype of cancer cells
    • Solimini,N.L. et al. (2007) Non-oncogene addiction and the stress phenotype of cancer cells. Cell, 130, 986-988.
    • (2007) Cell , vol.130 , pp. 986-988
    • Solimini, N.L.1
  • 36
    • 0036290257 scopus 로고    scopus 로고
    • Heat shock inhibits activation of NF-kappaB in the absence of heat shock factor-1
    • Malhotra,V. et al. (2002) Heat shock inhibits activation of NF-kappaB in the absence of heat shock factor-1. Biochem. Biophys. Res. Commun., 291, 453-457.
    • (2002) Biochem. Biophys. Res. Commun. , vol.291 , pp. 453-457
    • Malhotra, V.1
  • 37
    • 82355191506 scopus 로고    scopus 로고
    • NF-κB signaling pathway is inhibited by heat shock independently of active transcription factor HSF1 and increased levels of inducible heat shock proteins
    • Janus,P. et al. (2011) NF-κB signaling pathway is inhibited by heat shock independently of active transcription factor HSF1 and increased levels of inducible heat shock proteins. Genes Cells, 16, 1168-1175.
    • (2011) Genes Cells , vol.16 , pp. 1168-1175
    • Janus, P.1
  • 38
    • 79960008971 scopus 로고    scopus 로고
    • BAG3: a multifaceted protein that regulates major cell pathways
    • Rosati,A. et al. (2011) BAG3: a multifaceted protein that regulates major cell pathways. Cell Death Dis., 2, e141.
    • (2011) Cell Death Dis. , vol.2
    • Rosati, A.1
  • 39
    • 33748801507 scopus 로고    scopus 로고
    • BAG3 deficiency results in fulminant myopathy and early lethality
    • Homma,S. et al. (2006) BAG3 deficiency results in fulminant myopathy and early lethality. Am. J. Pathol., 169, 761-773.
    • (2006) Am. J. Pathol. , vol.169 , pp. 761-773
    • Homma, S.1
  • 40
    • 42949179530 scopus 로고    scopus 로고
    • Bag3 gene expression is regulated by heat shock factor 1
    • Franceschelli,S. et al. (2008) Bag3 gene expression is regulated by heat shock factor 1. J. Cell. Physiol., 215, 575-577.
    • (2008) J. Cell. Physiol. , vol.215 , pp. 575-577
    • Franceschelli, S.1
  • 41
    • 26444605834 scopus 로고    scopus 로고
    • IKK/NF-kappaB signaling: balancing life and death-a new approach to cancer therapy
    • Luo,J.L. et al. (2005) IKK/NF-kappaB signaling: balancing life and death-a new approach to cancer therapy. J. Clin. Invest., 115, 2625-2632.
    • (2005) J. Clin. Invest. , vol.115 , pp. 2625-2632
    • Luo, J.L.1
  • 42
    • 79959947025 scopus 로고    scopus 로고
    • Heat shock transcription factor 1 is a key determinant of HCC development by regulating hepatic steatosis and metabolic syndrome
    • Jin,X. et al. (2011) Heat shock transcription factor 1 is a key determinant of HCC development by regulating hepatic steatosis and metabolic syndrome. Cell Metab., 14, 91-103.
    • (2011) Cell Metab. , vol.14 , pp. 91-103
    • Jin, X.1
  • 43
    • 33846839443 scopus 로고    scopus 로고
    • Deletion of NEMO/IKKgamma in liver parenchymal cells causes steatohepatitis and hepatocellular carcinoma
    • Luedde,T. et al. (2007) Deletion of NEMO/IKKgamma in liver parenchymal cells causes steatohepatitis and hepatocellular carcinoma. Cancer Cell, 11, 119-132.
    • (2007) Cancer Cell , vol.11 , pp. 119-132
    • Luedde, T.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.