Pleiotropic molecular effects of the Mycobacterium ulcerans virulence factor mycolactone underlying the cell death and immunosuppression seen in Buruli ulcer

Biochemical Society Transactions

Volumn 42, Issue 1, 2014, Pages 177-183

  Hall, Belinda ^a   Simmonds, Rachel ^a  

^a UNIVERSITY OF SURREY   (United Kingdom)

Author keywords

Buruli ulcer; Gene regulation; Inflammation; Mycobacterium ulcerans; Mycolactone

Indexed keywords

CHEMOKINE RECEPTOR; LAT PROTEIN; LYMPHOCYTE FUNCTION ASSOCIATED ANTIGEN 1; MONOCYTE CHEMOTACTIC PROTEIN 1; MUSCLE RING FINGER 1 PROTEIN; MYCOLACTONE; NEURAL WISKOTT ALDRICH SYNDROME PROTEIN; POLYKETIDE SYNTHASE; PROTEIN KINASE ZAP 70; RANTES; T LYMPHOCYTE RECEPTOR; UNCLASSIFIED DRUG; UVOMORULIN; VIRULENCE FACTOR;

ARTICLE; BACTERIAL STRAIN; BONE MARROW CULTURE; BURULI ULCER; CELL ADHESION; CELL CYCLE ARREST; CELL DEATH; CELL DIVISION; CELL FUNCTION; CELL INTERACTION; CELL MATURATION; CELL PHAGOCYTOSIS; CELL PROLIFERATION; CELL VIABILITY; CYTOKINE PRODUCTION; CYTOTOXICITY; DOWN REGULATION; G1 PHASE CELL CYCLE CHECKPOINT; IMMUNE RESPONSE; IN VITRO STUDY; IN VIVO STUDY; MACROPHAGE; MYCOBACTERIUM ULCERANS; NONHUMAN; PATHOGENESIS; PERIPHERAL BLOOD MONONUCLEAR CELL; PLEIOTROPY; PRIORITY JOURNAL; PROTEIN DEPLETION; T LYMPHOCYTE; TARGET CELL;

ANIMALS; APOPTOSIS; BURULI ULCER; HOST-PATHOGEN INTERACTIONS; HUMANS; IMMUNE TOLERANCE; IMMUNITY, INNATE; MACROLIDES; MYCOBACTERIUM ULCERANS; PROTEIN BIOSYNTHESIS; VIRULENCE FACTORS;

EID: 84893310779     PISSN: 03005127     EISSN: 14708752     Source Type: Journal    
DOI: 10.1042/BST20130133     Document Type: Article

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