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Volumn 163, Issue 7, 1999, Pages 3928-3935

The inhibitory action of Mycobacterium ulcerans soluble factor on monocyte/T cell cytokine production and NF-κB function

Author keywords

[No Author keywords available]

Indexed keywords

IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1; INTERLEUKIN 10; INTERLEUKIN 2; PHORBOL ESTER; TOXIN; TUMOR NECROSIS FACTOR;

EID: 0033214405     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (129)

References (60)
  • 1
    • 0029941914 scopus 로고    scopus 로고
    • Mycobacterium ulcerans infection (Buruli ulcer): First reported patients in Togo
    • Meyers, W. M., N. Tignokpa, G. B. Priuli, and F. Portaels. 1996. Mycobacterium ulcerans infection (Buruli ulcer): first reported patients in Togo. Br. J. Dermatol. 134:1116.
    • (1996) Br. J. Dermatol. , vol.134 , pp. 1116
    • Meyers, W.M.1    Tignokpa, N.2    Priuli, G.B.3    Portaels, F.4
  • 2
    • 0001116515 scopus 로고
    • Mycobacterial skin ulcer in Uganda: Histopathological and experimental aspects
    • Dodge, O. G. 1964. Mycobacterial skin ulcer in Uganda: histopathological and experimental aspects. J. Pathol. Bacteriol. 88:167.
    • (1964) J. Pathol. Bacteriol. , vol.88 , pp. 167
    • Dodge, O.G.1
  • 3
    • 0000031558 scopus 로고
    • Buruli ulceration: A clinicopathologic study of 38 Ugandans with M. ulcerans ulceration
    • Connor, D. H., and F. Lunn. 1966. Buruli ulceration: a clinicopathologic study of 38 Ugandans with M. ulcerans ulceration. Arch. Pathol. 81:183.
    • (1966) Arch. Pathol. , vol.81 , pp. 183
    • Connor, D.H.1    Lunn, F.2
  • 4
    • 0040832695 scopus 로고
    • Mycobacterium ulcerans infection
    • Connor, D. H., and F. Lunn. 1965. Mycobacterium ulcerans infection. Int. J. Leprosy 33:698.
    • (1965) Int. J. Leprosy , vol.33 , pp. 698
    • Connor, D.H.1    Lunn, F.2
  • 6
    • 0027500073 scopus 로고
    • Out of africa: Observations on the histopathology of Mycobacterium ulcerans infection
    • Hayman, J. 1993. Out of Africa: observations on the histopathology of Mycobacterium ulcerans infection. J. Clin. Pathol. 46:5.
    • (1993) J. Clin. Pathol. , vol.46 , pp. 5
    • Hayman, J.1
  • 7
    • 0016131268 scopus 로고
    • Toxin of Mycobacterium ulcerans: Production and effects in guinea pig skin
    • Krieg, R. E., W. T. Hockmeyer, and D. H. Connor. 1974. Toxin of Mycobacterium ulcerans: production and effects in guinea pig skin. Arch. Dermatol. 110:783.
    • (1974) Arch. Dermatol. , vol.110 , pp. 783
    • Krieg, R.E.1    Hockmeyer, W.T.2    Connor, D.H.3
  • 10
    • 0017184389 scopus 로고
    • A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding
    • Bradford, M. M. 1976. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal. Biochem. 72:248.
    • (1976) Anal. Biochem. , vol.72 , pp. 248
    • Bradford, M.M.1
  • 11
    • 0031883476 scopus 로고    scopus 로고
    • Partial purification and characterization of biological effects of a lipid toxin produced by Mycobacterium ulcerans
    • George, K. M., L. P. Barker, D. M. Welty, and P. L. Small. 1998. Partial purification and characterization of biological effects of a lipid toxin produced by Mycobacterium ulcerans. Infect. Immun. 66:587.
    • (1998) Infect. Immun. , vol.66 , pp. 587
    • George, K.M.1    Barker, L.P.2    Welty, D.M.3    Small, P.L.4
  • 13
    • 0028983488 scopus 로고
    • + th1 cells pro-inflammatory or anti-inflammatory? The ratio of IL-10 to IFN-γ or IL-2 determines their function
    • + Th1 cells pro-inflammatory or anti-inflammatory? The ratio of IL-10 to IFN-γ or IL-2 determines their function. Int. Immunol. 7:1287.
    • (1995) Int. Immunol. , vol.7 , pp. 1287
    • Katsikis, P.D.1    Cohen, S.B.2    Londei, M.3    Feldmann, M.4
  • 14
    • 0029149947 scopus 로고
    • IL-10 and IL-3 synergize to cause proliferation of human T cells
    • Cohen, S. B. 1995. IL-10 and IL-3 synergize to cause proliferation of human T cells. Immunology 85:351.
    • (1995) Immunology , vol.85 , pp. 351
    • Cohen, S.B.1
  • 15
    • 0029891449 scopus 로고    scopus 로고
    • Paradoxical effects of a synthetic metalloproteinase inhibitor that blocks both p55 and p75 TNF receptor shedding and TNF α processing in RA synovial membrane cell cultures
    • Williams, L. M., D. L. Gibbons, A. Gearing, R. N. Maini, M. Feldmann, and F. M. Brennan. 1996. Paradoxical effects of a synthetic metalloproteinase inhibitor that blocks both p55 and p75 TNF receptor shedding and TNF α processing in RA synovial membrane cell cultures. J. Clin. Invest. 97:2833.
    • (1996) J. Clin. Invest. , vol.97 , pp. 2833
    • Williams, L.M.1    Gibbons, D.L.2    Gearing, A.3    Maini, R.N.4    Feldmann, M.5    Brennan, F.M.6
  • 16
    • 0022972464 scopus 로고
    • A highly sensitive cell line, WEHI 164 clone 13, for measuring cytotoxic factor/tumor necrosis factor from human monocytes
    • Espevik, T., and J. Nissen-Meyer. 1986. A highly sensitive cell line, WEHI 164 clone 13, for measuring cytotoxic factor/tumor necrosis factor from human monocytes. J. Immunol. Methods 95:99.
    • (1986) J. Immunol. Methods , vol.95 , pp. 99
    • Espevik, T.1    Nissen-Meyer, J.2
  • 17
    • 0026611676 scopus 로고
    • Strategies of anti-cytokine monoclonal antibody development: Immunoassay of IL-10 and IL-5 in clinical samples
    • Abrams, J. S., M. G. Roncarolo, H. Yssel, U. Andersson, G. J. Gleich, and J. E. Silver. 1992. Strategies of anti-cytokine monoclonal antibody development: immunoassay of IL-10 and IL-5 in clinical samples. Immunol. Rev. 127:5.
    • (1992) Immunol. Rev. , vol.127 , pp. 5
    • Abrams, J.S.1    Roncarolo, M.G.2    Yssel, H.3    Andersson, U.4    Gleich, G.J.5    Silver, J.E.6
  • 18
    • 0031944393 scopus 로고    scopus 로고
    • IL-10-mediated suppression of TNF-α production is independent of its ability to inhibit NF-κB activity
    • Clarke, C. J., A. Hales, A. Hunt, and B. M. Foxwell. 1998. IL-10-mediated suppression of TNF-α production is independent of its ability to inhibit NF-κB activity. Eur. J. Immunol. 28:1719.
    • (1998) Eur. J. Immunol. , vol.28 , pp. 1719
    • Clarke, C.J.1    Hales, A.2    Hunt, A.3    Foxwell, B.M.4
  • 19
    • 0018252771 scopus 로고
    • Rapid hypotonic method for flow cytofluorometry of monolayer cell cultures. Some pitfalls in staining and data analysis
    • Fried, J., A. G. Perez, and B. D. Clarkson. 1978. Rapid hypotonic method for flow cytofluorometry of monolayer cell cultures. Some pitfalls in staining and data analysis. J. Histochem. Cytochem. 26:921.
    • (1978) J. Histochem. Cytochem. , vol.26 , pp. 921
    • Fried, J.1    Perez, A.G.2    Clarkson, B.D.3
  • 20
    • 0025726216 scopus 로고
    • A rapid and simple method for measuring thymocyte apoptosis by propidium iodide staining and flow cytometry
    • Nicoletti, I., G. Migliorati, M. C. Pagliacci, F. Grignani, and C. Riccardi. 1991. A rapid and simple method for measuring thymocyte apoptosis by propidium iodide staining and flow cytometry. J. Immunol. Methods 139:271.
    • (1991) J. Immunol. Methods , vol.139 , pp. 271
    • Nicoletti, I.1    Migliorati, G.2    Pagliacci, M.C.3    Grignani, F.4    Riccardi, C.5
  • 21
    • 0014682747 scopus 로고
    • BCG vaccination against Mycobacterium ulcerans infection (Buruli ulcer)
    • Uganda-Buruli-Group. 1969. BCG vaccination against Mycobacterium ulcerans infection (Buruli ulcer). Lancet 1:111.
    • (1969) Lancet , vol.1 , pp. 111
  • 22
    • 0016441818 scopus 로고
    • The production and preliminary investigation of Burulin, a new skin test reagent for Mycobacterium ulcerans infection
    • Stanford, J. L., W. D. Revill, W. J. Gunthorpe, and J. M. Grange. 1975. The production and preliminary investigation of Burulin, a new skin test reagent for Mycobacterium ulcerans infection. J. Hyg. 74:7.
    • (1975) J. Hyg. , vol.74 , pp. 7
    • Stanford, J.L.1    Revill, W.D.2    Gunthorpe, W.J.3    Grange, J.M.4
  • 23
    • 0023902965 scopus 로고
    • Immunosuppressive properties of the soluble toxin from Mycobacterium ulcerans
    • Pimsler, M., T. A. Sponsler, and W. M. Meyers. 1988. Immunosuppressive properties of the soluble toxin from Mycobacterium ulcerans. J. Infect. Dis. 157:577.
    • (1988) J. Infect. Dis. , vol.157 , pp. 577
    • Pimsler, M.1    Sponsler, T.A.2    Meyers, W.M.3
  • 24
    • 0031873504 scopus 로고    scopus 로고
    • Cell surface and nuclear changes during TNF-α-induced apoptosis in WEHI 164 murine fibrosarcoma cells: A correlative light, scanning, and transmission electron microscopical study
    • Katsen, A. D., B. Vollmar, P. Mestres-Ventura, and M. D. Menger. 1998. Cell surface and nuclear changes during TNF-α-induced apoptosis in WEHI 164 murine fibrosarcoma cells: a correlative light, scanning, and transmission electron microscopical study. Virchows Arch. 433:75.
    • (1998) Virchows Arch. , vol.433 , pp. 75
    • Katsen, A.D.1    Vollmar, B.2    Mestres-Ventura, P.3    Menger, M.D.4
  • 25
    • 0031906550 scopus 로고    scopus 로고
    • Signal transduction through NF-κB
    • May, M. J., and S. Ghosh. 1998. Signal transduction through NF-κB. Immunol. Today 19:80.
    • (1998) Immunol. Today , vol.19 , pp. 80
    • May, M.J.1    Ghosh, A.S.2
  • 27
    • 0032488837 scopus 로고    scopus 로고
    • p38 and extracellular signal-regulated kinase mitogen-activated protein kinase pathways are required for nuclear factor-κB p65 transactivation mediated by tumor necrosis factor
    • Vanden Berghe, W., S. Plaisance, E. Boone, K. De Bosscher, M. L. Schmitz, W. Fiers, and G. Haegeman. 1998. p38 and extracellular signal-regulated kinase mitogen-activated protein kinase pathways are required for nuclear factor-κB p65 transactivation mediated by tumor necrosis factor. J. Biol. Chem. 273:3285.
    • (1998) J. Biol. Chem. , vol.273 , pp. 3285
    • Vanden Berghe, W.1    Plaisance, S.2    Boone, E.3    De Bosscher, K.4    Schmitz, M.L.5    Fiers, W.6    Haegeman, G.7
  • 28
    • 0025884625 scopus 로고
    • Tumor necrosis factor: Characterization at the molecular, cellular and in vivo level
    • Fiers, W. 1991. Tumor necrosis factor: characterization at the molecular, cellular and in vivo level. FEBS Lett. 285:199.
    • (1991) FEBS Lett. , vol.285 , pp. 199
    • Fiers, W.1
  • 29
    • 0028574382 scopus 로고
    • Interleukin-1, tumor necrosis factor and their specific inhibitors
    • Dayer, J. M., and D. Burger. 1994. Interleukin-1, tumor necrosis factor and their specific inhibitors. Eur. Cytokine Netw. 5:563.
    • (1994) Eur. Cytokine Netw. , vol.5 , pp. 563
    • Dayer, J.M.1    Burger, D.2
  • 30
    • 0023706894 scopus 로고
    • Release of reactive nitrogen intermediates and reactive oxygen intermediates from mouse peritoneal macrophages: Comparison of activating cytokines and evidence for independent production
    • Ding, A. H., C. F. Nathan, and D. J. Stuehr. 1988. Release of reactive nitrogen intermediates and reactive oxygen intermediates from mouse peritoneal macrophages: comparison of activating cytokines and evidence for independent production. J. Immunol. 141:2407.
    • (1988) J. Immunol. , vol.141 , pp. 2407
    • Ding, A.H.1    Nathan, C.F.2    Stuehr, D.J.3
  • 31
    • 0023934091 scopus 로고
    • Tumor necrosis factor, alone or in combination with IL-2, but not IFN-γ, is associated with macrophage killing of Mycobacterium avium complex
    • Bermudez, L. E., and L. S. Young. 1988. Tumor necrosis factor, alone or in combination with IL-2, but not IFN-γ, is associated with macrophage killing of Mycobacterium avium complex. J. Immunol. 140:3006.
    • (1988) J. Immunol. , vol.140 , pp. 3006
    • Bermudez, L.E.1    Young, L.S.2
  • 34
    • 0029007855 scopus 로고
    • The TNF receptor 1-associated protein TRADD signals cell death and NF-κB activation
    • Hsu, H., J. Xiong, and D. V. Goeddel. 1995. The TNF receptor 1-associated protein TRADD signals cell death and NF-κB activation. Cell 81:495.
    • (1995) Cell , vol.81 , pp. 495
    • Hsu, H.1    Xiong, J.2    Goeddel, D.V.3
  • 35
    • 0029949257 scopus 로고    scopus 로고
    • TNF-dependent recruitment of the protein kinase RIP to the TNF receptor-1 signaling complex
    • Hsu, H., J. Huang, H. B. Shu, V. Baichwal, and D. V. Goeddel. 1996. TNF-dependent recruitment of the protein kinase RIP to the TNF receptor-1 signaling complex. Immunity 4:387.
    • (1996) Immunity , vol.4 , pp. 387
    • Hsu, H.1    Huang, J.2    Shu, H.B.3    Baichwal, V.4    Goeddel, D.V.5
  • 36
    • 0031017618 scopus 로고    scopus 로고
    • MAP3K-related kinase involved in NF-κB induction by TNF, CD95 and IL-1
    • Malinin, N. L., M. P. Boldin, A. V. Kovalenko, and D. Wallach. 1997. MAP3K-related kinase involved in NF-κB induction by TNF, CD95 and IL-1. Nature 385:540.
    • (1997) Nature , vol.385 , pp. 540
    • Malinin, N.L.1    Boldin, M.P.2    Kovalenko, A.V.3    Wallach, D.4
  • 37
    • 0030032106 scopus 로고    scopus 로고
    • TRADD-TRAF2 and TRADD-FADD interactions define two distinct TNF receptor 1 signal transduction pathways
    • Hsu, H., H. B. Shu, M. G. Pan, and D. V. Goeddel. 1996 TRADD-TRAF2 and TRADD-FADD interactions define two distinct TNF receptor 1 signal transduction pathways. Cell 84:299.
    • (1996) Cell , vol.84 , pp. 299
    • Hsu, H.1    Shu, H.B.2    Pan, M.G.3    Goeddel, D.V.4
  • 38
    • 0031897632 scopus 로고    scopus 로고
    • NF-κB and Rel proteins: Evolutionarily conserved mediators of immune responses
    • Ghosh, S., M. J. May, and E. B. Kopp. 1998. NF-κB and Rel proteins: evolutionarily conserved mediators of immune responses. Annu. Rev. Immunol. 16:225.
    • (1998) Annu. Rev. Immunol. , vol.16 , pp. 225
    • Ghosh, S.1    May, M.J.2    Kopp, E.B.3
  • 40
    • 0031437893 scopus 로고    scopus 로고
    • Activation of nuclear transcription factor NF-κB by interleukin-1 is accompanied by casein kinase II-mediated phosphorylation of the p65 subunit
    • Bird, T. A., K. Schooley, S. K. Dower, H. Hagen, and G. D. Virca. 1997. Activation of nuclear transcription factor NF-κB by interleukin-1 is accompanied by casein kinase II-mediated phosphorylation of the p65 subunit. J. Biol. Chem. 272:32606.
    • (1997) J. Biol. Chem. , vol.272 , pp. 32606
    • Bird, T.A.1    Schooley, K.2    Dower, S.K.3    Hagen, H.4    Virca, G.D.5
  • 41
    • 0028984263 scopus 로고
    • Tumor necrosis factor-α-dependent activation of a RelA homodimer in astrocytes: Increased phosphorylation of RelA and MAD-3 precede activation of RelA
    • Diehl, J. A., W. Tong, G. Sun, and M. Hannink. 1995. Tumor necrosis factor-α-dependent activation of a RelA homodimer in astrocytes: increased phosphorylation of RelA and MAD-3 precede activation of RelA. J. Biol. Chem. 270:2703.
    • (1995) J. Biol. Chem. , vol.270 , pp. 2703
    • Diehl, J.A.1    Tong, W.2    Sun, G.3    Hannink, M.4
  • 42
    • 0030882666 scopus 로고    scopus 로고
    • Oncogenic Ha-Ras-induced signaling activates NF-κB transcriptional activity, which is required for cellular transformation
    • Finco, T. S., J. K. Westwick, J. L. Norris, A. A. Beg, C. J. Der, and A. S. Baldwin, Jr. 1997. Oncogenic Ha-Ras-induced signaling activates NF-κB transcriptional activity, which is required for cellular transformation. J. Biol. Chem. 272:24113.
    • (1997) J. Biol. Chem. , vol.272 , pp. 24113
    • Finco, T.S.1    Westwick, J.K.2    Norris, J.L.3    Beg, A.A.4    Der, C.J.5    Baldwin A.S., Jr.6
  • 43
    • 0028170265 scopus 로고
    • Activation of NF-κB in vivo is regulated by multiple phosphorylations
    • Naumann, M., and C. Scheidereit. 1994. Activation of NF-κB in vivo is regulated by multiple phosphorylations. EMBO J. 13:4597.
    • (1994) EMBO J. , vol.13 , pp. 4597
    • Naumann, M.1    Scheidereit, C.2
  • 44
    • 0029058962 scopus 로고
    • Transactivation domain 2 (TA2) of p65 NF-κB: Aimilarity to TA1 and phorbol ester-stimulated activity and phosphorylation in intact cells
    • Schmitz, M. L., M. A. dos Santos Silva, and P. A. Baeuerle. 1995. Transactivation domain 2 (TA2) of p65 NF-κB: aimilarity to TA1 and phorbol ester-stimulated activity and phosphorylation in intact cells. J. Biol. Chem. 270:15576.
    • (1995) J. Biol. Chem. , vol.270 , pp. 15576
    • Schmitz, M.L.1    Dos Santos Silva, M.A.2    Baeuerle, P.A.3
  • 45
    • 0032491485 scopus 로고    scopus 로고
    • Activation of nuclear factor-KB-dependent transcription by tumor necrosis factor-α is mediated through phosphorylation of RelA/p65 on serine 529
    • Wang, D., and A. S. Baldwin, Jr. 1998. Activation of nuclear factor-KB-dependent transcription by tumor necrosis factor-α is mediated through phosphorylation of RelA/p65 on serine 529. J. Biol. Chem. 273:29411.
    • (1998) J. Biol. Chem. , vol.273 , pp. 29411
    • Wang, D.1    Baldwin A.S., Jr.2
  • 46
    • 0032571569 scopus 로고    scopus 로고
    • TRAF2 plays a dual rote in NF-κB-dependent gene activation by mediating the TNF-induced activation of p38 MAPK and IκB kinase pathways
    • Carpentier, I., W. Declercq, N. L. Malinin, D. Wallach, W. Fiers, and R. Beyaert. 1998. TRAF2 plays a dual rote in NF-κB-dependent gene activation by mediating the TNF-induced activation of p38 MAPK and IκB kinase pathways. FEBS Lett. 425:195.
    • (1998) FEBS Lett. , vol.425 , pp. 195
    • Carpentier, I.1    Declercq, W.2    Malinin, N.L.3    Wallach, D.4    Fiers, W.5    Beyaert, R.6
  • 47
    • 0032055225 scopus 로고    scopus 로고
    • Activation of caspase 3 (CPP32)-like proteases is essential for TNF-α-induced hepatic parenchymal cell apoptosis and neutrophil-mediated necrosis in a murine endotoxin shock model
    • Jaeschke, H., M. A. Fisher, J. A. Lawson, C. A. Simmons, A. Farhood, and D. A. Jones. 1998. Activation of caspase 3 (CPP32)-like proteases is essential for TNF-α-induced hepatic parenchymal cell apoptosis and neutrophil-mediated necrosis in a murine endotoxin shock model. J. Immunol. 160:3480.
    • (1998) J. Immunol. , vol.160 , pp. 3480
    • Jaeschke, H.1    Fisher, M.A.2    Lawson, J.A.3    Simmons, C.A.4    Farhood, A.5    Jones, D.A.6
  • 50
    • 0031423761 scopus 로고    scopus 로고
    • MyD88: An adapter that recruits IRAK to the IL-1 receptor complex
    • Wesche, H., W. J. Henzel, W. Shillinglaw, S. Li, and Z. Cao. 1997. MyD88: an adapter that recruits IRAK to the IL-1 receptor complex Immunity 7:837.
    • (1997) Immunity , vol.7 , pp. 837
    • Wesche, H.1    Henzel, W.J.2    Shillinglaw, W.3    Li, S.4    Cao, Z.5
  • 51
    • 0028982919 scopus 로고
    • NF-κB activation by interleukin-1 (IL-I) requires an IL-1 receptor-associated protein kinase activity
    • Croston, G. E., Z. Cao, and D. V. Goeddel. 1995. NF-κB activation by interleukin-1 (IL-I) requires an IL-1 receptor-associated protein kinase activity. J. Biol. Chem. 270:16514.
    • (1995) J. Biol. Chem. , vol.270 , pp. 16514
    • Croston, G.E.1    Cao, Z.2    Goeddel, D.V.3
  • 53
    • 0029865142 scopus 로고    scopus 로고
    • IRAK: A kinase associated with the interleukin-1 receptor
    • Cao, Z., W. J. Henzel, and X. Gao. 1996. IRAK: a kinase associated with the interleukin-1 receptor. Science 271:1128.
    • (1996) Science , vol.271 , pp. 1128
    • Cao, Z.1    Henzel, W.J.2    Gao, X.3
  • 55
    • 0031914323 scopus 로고    scopus 로고
    • The antibiotic rifampicin is a nonsteroidal ligand and activator of the human glucocorticoid receptor
    • Calleja, C. J., M. Pascussi, J. C. J. C. Mani, P. P. Maurel, and M. J. Vilarem. 1998. The antibiotic rifampicin is a nonsteroidal ligand and activator of the human glucocorticoid receptor. Nat. Med. 4:92.
    • (1998) Nat. Med. , vol.4 , pp. 92
    • Calleja, C.J.1    Pascussi, M.2    Mani, J.C.J.C.3    Maurel, P.P.4    Vilarem, M.J.5
  • 56
    • 0018921055 scopus 로고
    • Effect of rifampin on the immune response in mice
    • Bellahsène, A., and A. Forsgren. 1980. Effect of rifampin on the immune response in mice. Infect. Immun. 27:15.
    • (1980) Infect. Immun. , vol.27 , pp. 15
    • Bellahsène, A.1    Forsgren, A.2
  • 57
    • 0019627597 scopus 로고
    • Effect of rifampicin on body immunological reactivity
    • Chemushenko, E. F., and V. A. Shiniberov. 1981. Effect of rifampicin on body immunological reactivity. Antibiotiki 26:743.
    • (1981) Antibiotiki , vol.26 , pp. 743
    • Chemushenko, E.F.1    Shiniberov, V.A.2
  • 60
    • 0029979369 scopus 로고    scopus 로고
    • Biologic basis for interleukin-1 in disease
    • Dinarello, C. A. 1996. Biologic basis for interleukin-1 in disease. Blood 87:2095.
    • (1996) Blood , vol.87 , pp. 2095
    • Dinarello, C.A.1


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