Altered emotion processing circuits during the anticipation of emotional stimuli in women with borderline personality disorder

European Archives of Psychiatry and Clinical Neuroscience

Volumn 264, Issue 1, 2014, Pages 45-60

  Scherpiet, Sigrid ^a,b   Brühl, Annette B ^a   Opialla, Sarah ^a,b   Roth, Lilian ^a   Jäncke, Lutz ^b   Herwig, Uwe ^a,c  

^a UNIVERSITY HOSPITAL OF PSYCHIATRY ZURICH   (Switzerland)

^b UNIVERSITY OF ZURICH   (Switzerland)

^c UNIVERSITY OF ULM   (Germany)

Author keywords

Anticipation; Borderline personality disorder; Emotion; fMRI; Neurobiology

Indexed keywords

ADULT; ANTERIOR CINGULATE; ANTICIPATION; ARTICLE; BORDERLINE STATE; CLINICAL ARTICLE; CONTROLLED STUDY; ELECTROENCEPHALOGRAM; EMOTION; EMOTIONAL DISORDER; FEMALE; FUNCTIONAL MAGNETIC RESONANCE IMAGING; FUNCTIONAL NEUROIMAGING; HUMAN; LINGUAL GYRUS; MAJOR DEPRESSION; MENTAL PATIENT; MIDDLE AGED; PERCEPTION; POSTERIOR CINGULATE; PREFRONTAL CORTEX; PRIORITY JOURNAL; PSYCHOMETRY; VISUAL STIMULATION; YOUNG ADULT;

ADULT; AFFECTIVE SYMPTOMS; BORDERLINE PERSONALITY DISORDER; BRAIN; BRAIN MAPPING; FEMALE; HUMANS; IMAGE PROCESSING, COMPUTER-ASSISTED; MAGNETIC RESONANCE IMAGING; MIDDLE AGED; MOTIVATION; OXYGEN; PHOTIC STIMULATION; PSYCHOMETRICS; SELF REPORT; YOUNG ADULT;

EID: 84893270437     PISSN: 09401334     EISSN: 14338491     Source Type: Journal    
DOI: 10.1007/s00406-013-0444-x     Document Type: Article

References (106)

1. Bohus M, Kröger C (2011) Psychopathologie und Psychotherapie der Borderline-Persönlichkeitsstörung. Der Nervenarzt 82(1):16-24
2. Lieb K, Zanarini MC, Schmahl C, Linehan MM, Bohus M (2004) Borderline personality disorder. Lancet 364(9432):453-461
3. Leichsenring F, Leibing E, Kruse J, New AS, Leweke F (2011) Borderline personality disorder. The Lancet 377(9759):74-84
4. Linehan MM (1993) Skills training manual for treating borderline personality disorder. Guilford Press, New York
5. Rosenthal MZ, Gratz KL, Kosson DS, Cheavens JS, Lejuez CW, Lynch TR (2008) Borderline personality disorder and emotional responding: a review of the research literature. Clin Psychol Rev 28(1):75-91
6. Mauchnik J, Schmahl C (2010) The latest neuroimaging findings in borderline personality disorder. Curr Psychiatry Rep 12(1):46-55
7. O'Neill A, Frodl T (2012) Brain structure and function in borderline personality disorder. Brain Struct Funct 217(4):767-782
8. Herpertz SC, Dietrich TM, Wenning B, Krings T, Erberich SG, Willmes K, Thron A, Sass H (2001) Evidence of abnormal amygdala functioning in borderline personality disorder: a functional MRI study. Biol Psychiatry 50(4):292-298
9. Koenigsberg HW, Siever LJ, Lee H, Pizzarello S, New AS, Goodman M, Cheng H, Flory J, Prohovnik I (2009) Neural correlates of emotion processing in borderline personality disorder. Psychiatry Res 172(3):192-199
10. Schulze L, Domes G, Kruger A, Berger C, Fleischer M, Prehn K, Schmahl C, Grossmann A, Hauenstein K, Herpertz SC (2011) Neuronal correlates of cognitive reappraisal in borderline patients with affective instability. Biol Psychiatry 69(6):564-573
11. Hazlett EA, Zhang J, New AS, Zelmanova Y, Goldstein KE, Haznedar MM, Meyerson D, Goodman M, Siever LJ, Chu KW (2012) Potentiated amygdala response to repeated emotional pictures in borderline personality disorder. Biol Psychiatry 72(6):448-456
12. Minzenberg MJ, Fan J, New AS, Tang CY, Siever LJ (2007) Fronto-limbic dysfunction in response to facial emotion in borderline personality disorder: an event-related fMRI study. Psychiatry Res 155(3):231-243
13. Donegan NH, Sanislow CA, Blumberg HP, Fulbright RK, Lacadie C, Skudlarski P, Gore JC, Olson IR, McGlashan TH, Wexler BE (2003) Amygdala hyperreactivity in borderline personality disorder: implications for emotional dysregulation. Biol Psychiatry 54(11):1284-1293
14. Driessen M, Beblo T, Mertens M, Piefke M, Rullkoetter N, Silva-Saavedra A, Reddemann L, Rau H, Markowitsch HJ, Wulff H, Lange W, Woermann FG (2004) Posttraumatic stress disorder and fMRI activation patterns of traumatic memory in patients with borderline personality disorder. Biol Psychiatry 55(6):603-611
15. New AS, Hazlett EA, Buchsbaum MS, Goodman M, Mitelman SA, Newmark R, Trisdorfer R, Haznedar MM, Koenigsberg HW, Flory J, Siever LJ (2007) Amygdala-prefrontal disconnection in borderline personality disorder. Neuropsychopharmacology 32(7):1629-1640
16. Cullen KR, Vizueta N, Thomas KM, Han GJ, Lim KO, Camchong J, Mueller BA, Bell CH, Heller MD, Schulz SC (2011) Amygdala functional connectivity in young women with borderline personality disorder. Brain Connect 1(1):61-71
17. Bohus M, Schmahl C, Lieb K (2004) New developments in the neurobiology of borderline personality disorder. Curr Psychiatry Rep 6(1):43-50
18. New A, Perez-Rodriguez M, Ripoll L (2012) Neuroimaging and Borderline Personality Disorder. Psychiatric Annals 42(2):65-71. doi: 10.3928/00485713- 20120124-07
19. Tebartz van Elst L, Hesslinger B, Thiel T, Geiger E, Haegele K, Lemieux L, Lieb K, Bohus M, Hennig J, Ebert D (2003) Frontolimbic brain abnormalities in patients with borderline personality disorder: a volumetric magnetic resonance imaging study. Biol Psychiatry 54(2):163-171
20. Hazlett EA, New AS, Newmark R, Haznedar MM, Lo JN, Speiser LJ, Chen AD, Mitropoulou V, Minzenberg M, Siever LJ, Buchsbaum MS (2005) Reduced anterior and posterior cingulate gray matter in borderline personality disorder. Biol Psychiatry 58(8):614-623
21. Schmahl CG, Vermetten E, Elzinga BM, Bremner JD (2004) A positron emission tomography study of memories of childhood abuse in borderline personality disorder. Biol Psychiatry 55(7):759-765
22. Schmahl CG, Elzinga BM, Vermetten E, Sanislow C, McGlashan TH, Bremner JD (2003) Neural correlates of memories of abandonment in women with and without borderline personality disorder. Biol Psychiatry 54(2):142-151
23. Ochsner KN, Gross JJ (2005) The cognitive control of emotion. Trends Cogn Sci 9(5):242-249
24. Carter C (2000) Images in neuroscience. Cognition: executive function. Am J Psychiatry 157(1):3
25. Herwig U, Abler B, Walter H, Erk S (2007) Expecting unpleasant stimuli - an fMRI study. Psychiatry Res 154(1):1-12
26. Herwig U, Kaffenberger T, Baumgartner T, Jäncke L (2007) Neural correlates of a 'pessimistic' attitude when anticipating events of unknown emotional valence. Neuroimage 34(2):848-858
27. Beck AT (1967) Depression: clinical, experimental, and theoretical aspects. Harper & Row, New York
28. Abler B, Erk S, Herwig U, Walter H (2007) Anticipation of aversive stimuli activates extended amygdala in unipolar depression. J Psychiatr Res 41(6):511-522
29. Herwig U, Brühl AB, Kaffenberger T, Baumgartner T, Boeker H, Jäncke L (2010) Neural correlates of 'pessimistic' attitude in depression. Psychol Med 40(5):789-800
30. Bogels SM, Mansell W (2004) Attention processes in the maintenance and treatment of social phobia: hypervigilance, avoidance and self-focused attention. Clin Psychol Rev 24(7):827-856
31. Heinrichs N, Hofmann SG (2001) Information processing in social phobia: a critical review. Clin Psychol Rev 21(5):751-770
32. Brühl AB, Rufer M, Delsignore A, Kaffenberger T, Jancke L, Herwig U (2011) Neural correlates of altered general emotion processing in social anxiety disorder. Brain Res 1378:72-83
33. Bruehl AB, Herwig U, Delsignore A, Jancke L, Rufer M (2013) General emotion processing in social anxiety disorder: neural issues of cognitive control. Psychiatry Res 212(2):108-115
34. Enkel T, Gholizadeh D, von Bohlen und Halbach O, Sanchis-Segura C, Hurlemann R, Spanagel R, Gass P, Vollmayr B (2010) Ambiguous-cue interpretation is biased under stress- and depression-like states in rats. Neuropsychopharmacology 35(4):1008-1015
35. Bermpohl F, Pascual-Leone A, Amedi A, Merabet LB, Fregni F, Gaab N, Alsop D, Schlaug G, Northoff G (2006) Attentional modulation of emotional stimulus processing: an fMRI study using emotional expectancy. Hum Brain Mapp 27(8):662-677
36. Nitschke JB, Sarinopoulos I, Mackiewicz KL, Schaefer HS, Davidson RJ (2006) Functional neuroanatomy of aversion and its anticipation. Neuroimage 29(1):106-116
37. Ueda K, Okamoto Y, Okada G, Yamashita H, Hori T, Yamawaki S (2003) Brain activity during expectancy of emotional stimuli: an fMRI study. NeuroReport 14(1):51-55
38. Wager TD, Rilling JK, Smith EE, Sokolik A, Casey KL, Davidson RJ, Kosslyn SM, Rose RM, Cohen JD (2004) Placebo-induced changes in FMRI in the anticipation and experience of pain. Science 303(5661):1162-1167
39. Gilbert DT, Wilson TD (2007) Prospection: experiencing the future. Science 317(5843):1351-1354
40. Schacter DL, Addis DR, Buckner RL (2007) Remembering the past to imagine the future: the prospective brain. Nat Rev Neurosci 8(9):657-661
41. Enzi B, Doering S, Faber C, Hinrichs J, Bahmer J, Northoff G (2013) Reduced deactivation in reward circuitry and midline structures during emotion processing in borderline personality disorder. World J Biol Psychiatry 14(1):45-56
42. Baumeister RF, Vohs KD, DeWall CN, Liqing Z (2007) How emotion shapes behavior: feedback, anticipation, and reflection, rather than direct causation. Pers Soc Psychol Rev 11(2):167-203. doi: 10.1177/1088868307301033
43. Kamphausen S, Schroder P, Maier S, Bader K, Feige B, Kaller CP, Glauche V, Ohlendorf S, Tebartz van Elst L, Kloppel S, Jacob GA, Silbersweig D, Lieb K, Tuscher O (2013) Medial prefrontal dysfunction and prolonged amygdala response during instructed fear processing in borderline personality disorder. World J Biol Psychiatry 14(4):307-318 (S301-S304)
44. Kalisch R, Wiech K, Herrmann K, Dolan RJ (2006) Neural correlates of self-distraction from anxiety and a process model of cognitive emotion regulation. J Cogn Neurosci 18(8):1266-1276
45. Koenigsberg HW, Fan J, Ochsner KN, Liu X, Guise KG, Pizzarello S, Dorantes C, Guerreri S, Tecuta L, Goodman M, New A, Siever LJ (2009) Neural correlates of the use of psychological distancing to regulate responses to negative social cues: a study of patients with borderline personality disorder. Biol Psychiatry 66(9):854-863
46. Vogt BA, Berger GR, Derbyshire SW (2003) Structural and functional dichotomy of human midcingulate cortex. Eur J Neurosci 18(11):3134-3144
47. Vogt BA, Vogt L (2003) Cytology of human dorsal midcingulate and supplementary motor cortices. J Chem Neuroanat 26(4):301-309
48. Olsson A, Ochsner KN (2008) The role of social cognition in emotion. Trends Cogn Sci 12(2):65-71
49. Annett M (1970) A classification of hand preference by association analysis. Br J Psychol 61(3):303-321
50. American Psychiatric Association (2000) Task Force on D-I. Diagnostic and statistical manual of mental disorders: DSM-IV-TR. American Psychiatric Association, Washington, DC
51. Bohus M, Kleindienst N, Limberger MF, Stieglitz RD, Domsalla M, Chapman AL, Steil R, Philipsen A, Wolf M (2009) The short version of the Borderline Symptom List (BSL-23): development and initial data on psychometric properties. Psychopathology 42(1):32-39
52. Wolf M, Limberger MF, Kleindienst N, Stieglitz RD, Domsalla M, Philipsen A, Steil R, Bohus M (2009) Short version of the borderline symptom list (BSL-23): development and psychometric evaluation. Psychother Psychosom Med Psychol 59(8):321-324
53. Ackenheil M, Stotz G, Dietz-Bauer R, Vossen A (1999) Mini-international neuropsychiatric interview - German version 5.0.0. Psychiatrische Universitätsklinik München, München
54. Sheehan DV, Lecrubier Y, Sheehan KH, Amorim P, Janavs J, Weiller E, Hergueta T, Baker R, Dunbar GC (1998) The mini-international neuropsychiatric interview (M.I.N.I.): the development and validation of a structured diagnostic psychiatric interview for DSM-IV and ICD-10. J Clin Psychiatry 59(Suppl 20):22-33
55. Becker DF, Grilo CM, Edell WS, McGlashan TH (2000) Comorbidity of borderline personality disorder with other personality disorders in hospitalized adolescents and adults. Am J Psychiatry 157(12):2011-2016
56. Gunderson JG, Stout RL, Sanislow CA, Shea MT, McGlashan TH, Zanarini MC, Daversa MT, Grilo CM, Yen S, Skodol AE (2008) New episodes and new onsets of major depression in borderline and other personality disorders. J Affect Disord 111(1):40-45
57. Zanarini MC, Frankenbur FR, Weingeroff JL, Reich DB, Fitzmaurice GM, Weiss RD (2011) The course of substance use disorders in patients with borderline personality disorder and Axis II comparison subjects: a 10-year follow-up study. Addiction 106(2):342-348
58. Hamilton M (1960) A rating scale for depression. J Neurol Neurosurg Psychiatry 23:56-62
59. Montgomery SA, Asberg M (1979) A new depression scale designed to be sensitive to change. Br J Psychiatry 134:382-389
60. Hautzinger M, Bailer M, Worall H, Keller F (1995) Beck-depressions- inventar (BDI). Hans Huber, Bern
61. Zung WW (2005) Self-Rating Depression Scale. In: Cips CIPS (ed) Internationale Skalen für Psychiatrie. Beltz, Göttingen
62. Laux L, Glanzmann P, Schaffner P, Spielberger CD (1981) Das state-trait-angstinventar. Beltz, Weinheim
63. Bernstein DP, Fink L (1998) Childhood Trauma Questionnaire: a retrospective self-report manual. The Psychological Corporation, San Antonio, TX
64. Stiglmayr CE, Braakmann D, Haaf B, Stieglitz RD, Bohus M (2003) Development and characteristics of Dissociation-Tension-Scale acute (DSS-Akute). Psychother Psychosom Med Psychol 53(7):287-294
65. Stiglmayr C, Schmahl C, Bremner JD, Bohus M, Ebner-Priemer U (2009) Development and psychometric characteristics of the DSS-4 as a short instrument to assess dissociative experience during neuropsychological experiments. Psychopathology 42(6):370-374
66. Lang PJ, Bradley MM, Cuthbert BN (2005) International affective picture system (IAPS): affective ratings of pictures and instruction manual. Technical report A-6. Center for Research in Psychophysiology, University of Florida, Gainesville, FL
67. Goebel R, Esposito F, Formisano E (2006) Analysis of functional image analysis contest (FIAC) data with brainvoyager QX: from single-subject to cortically aligned group general linear model analysis and self-organizing group independent component analysis. Hum Brain Mapp 27(5):392-401
68. Talairach J, Tournoux P (1988) Co-planar stereotaxic atlas of the human brain: three-dimensional proportional system. Thieme Medical, New York
69. Lancaster JL, Woldorff MG, Parsons LM, Liotti M, Freitas CS, Rainey L, Kochunov PV, Nickerson D, Mikiten SA, Fox PT (2000) Automated Talairach atlas labels for functional brain mapping. Hum Brain Mapp 10(3):120-131
70. Kastner S, O'Connor DH, Fukui MM, Fehd HM, Herwig U, Pinsk MA (2004) Functional imaging of the human lateral geniculate nucleus and pulvinar. J Neurophysiol 91(1):438-448
71. Tanaka-Matsumi J, Kameoka VA (1986) Reliabilities and concurrent validities of popular self-report measures of depression, anxiety, and social desirability. J Consult Clin Psychol 54(3):328-333
72. Ochsner KN, Silvers JA, Buhle JT (2012) Functional imaging studies of emotion regulation: a synthetic review and evolving model of the cognitive control of emotion. Ann N Y Acad Sci 1251:E1-24
73. Rushworth MF, Buckley MJ, Behrens TE, Walton ME, Bannerman DM (2007) Functional organization of the medial frontal cortex. Curr Opin Neurobiol 17(2):220-227
74. Bush G, Luu P, Posner MI (2000) Cognitive and emotional influences in anterior cingulate cortex. Trends Cogn Sci 4(6):215-222
75. Posner MI, Petersen SE, Fox PT, Raichle ME (1988) Localization of cognitive operations in the human brain. Science 240(4859):1627-1631
76. Pardo JV, Pardo PJ, Janer KW, Raichle ME (1990) The anterior cingulate cortex mediates processing selection in the Stroop attentional conflict paradigm. Proc Natl Acad Sci U S A 87(1):256-259
77. Carter CS, Braver TS, Barch DM, Botvinick MM, Noll D, Cohen JD (1998) Anterior cingulate cortex, error detection, and the online monitoring of performance. Science 280(5364):747-749
78. Murtha S, Chertkow H, Beauregard M, Dixon R, Evans A (1996) Anticipation causes increased blood flow to the anterior cingulate cortex. Hum Brain Mapp 4(2):103-112
79. Vogt BA (2005) Pain and emotion interactions in subregions of the cingulate gyrus. Nat Rev Neurosci 6(7):533-544
80. Disner SG, Beevers CG, Haigh EA, Beck AT (2011) Neural mechanisms of the cognitive model of depression. Nat Rev Neurosci 12(8):467-477
81. Kalisch R (2009) The functional neuroanatomy of reappraisal: time matters. Neurosci Biobehav Rev 33(8):1215-1226
82. Kanske P, Heissler J, Schönfelder S, Bongers A, Wessa M (2011) How to regulate emotion? Neural networks for reappraisal and distraction. Cereb Cortex. doi: 10.1093/cercor/bhq216
83. Diekhof EK, Geier K, Falkai P, Gruber O (2011) Fear is only as deep as the mind allows: a coordinate-based meta-analysis of neuroimaging studies on the regulation of negative affect. NeuroImage 58:275-285
84. Salavert J, Gasol M, Vieta E, Cervantes A, Trampal C, Gispert JD (2011) Fronto-limbic dysfunction in borderline personality disorder: a 18F-FDG positron emission tomography study. J Affect Disord 131(1-3):260-267
85. Ruocco AC, Medaglia JD, Ayaz H, Chute DL (2010) Abnormal prefrontal cortical response during affective processing in borderline personality disorder. Psychiatry Res 182(2):117-122
86. Ruocco AC, Amirthavasagam S, Choi-Kain LW, McMain SF (2013) Neural correlates of negative emotionality in borderline personality disorder: an activation-likelihood-estimation meta-analysis. Biol Psychiatry 73(2):153-160
87. Baer RA, Peters JR, Eisenlohr-Moul TA, Geiger PJ, Sauer SE (2012) Emotion-related cognitive processes in borderline personality disorder: a review of the empirical literature. Clin Psychol Rev 32(5):359-369
88. Palomero-Gallagher N, Vogt BA, Schleicher A, Mayberg HS, Zilles K (2009) Receptor architecture of human cingulate cortex: evaluation of the four-region neurobiological model. Hum Brain Mapp 30(8):2336-2355
89. Sacher J, Neumann J, Funfstuck T, Soliman A, Villringer A, Schroeter ML (2012) Mapping the depressed brain: a meta-analysis of structural and functional alterations in major depressive disorder. J Affect Disord 140(2):142-148
90. Drevets WC (2001) Neuroimaging and neuropathological studies of depression: implications for the cognitive-emotional features of mood disorders. Curr Opin Neurobiol 11(2):240-249
91. Bogousslavsky J, Miklossy J, Deruaz JP, Assal G, Regli F (1987) Lingual and fusiform gyri in visual processing: a clinico-pathologic study of superior altitudinal hemianopia. J Neurol Neurosurg Psychiatry 50(5):607-614
92. Hopfinger JB, Buonocore MH, Mangun GR (2000) The neural mechanisms of top-down attentional control. Nat Neurosci 3(3):284-291
93. Kelly SP, Gomez-Ramirez M, Foxe JJ (2008) Spatial attention modulates initial afferent activity in human primary visual cortex. Cereb Cortex 18(11):2629-2636
94. Rauss KS, Pourtois G, Vuilleumier P, Schwartz S (2009) Attentional load modifies early activity in human primary visual cortex. Hum Brain Mapp 30(5):1723-1733
95. Bremner JD, Narayan M, Staib LH, Southwick SM, McGlashan T, Charney DS (1999) Neural correlates of memories of childhood sexual abuse in women with and without posttraumatic stress disorder. Am J Psychiatry 156(11):1787-1795
96. Northoff G, Heinzel A, de Greck M, Bermpohl F, Dobrowolny H, Panksepp J (2006) Self-referential processing in our brain-a meta-analysis of imaging studies on the self. Neuroimage 31(1):440-457
97. Vogt BA, Finch DM, Olson CR (1992) Functional heterogeneity in cingulate cortex: the anterior executive and posterior evaluative regions. Cereb Cortex 2(6):435-443
98. Lang PJ, Levin DN, Miller GA, Kozak MJ (1983) Fear behavior, fear imagery, and the psychophysiology of emotion: the problem of affective response integration. J Abnorm Psychol 92(3):276-306
99. Beck AT, Freeman A (1990) Cognitive therapy of personality disorders. Guilford, New York
100. Linehan M (1993) Cognitive-behavioral treatment of borderline personality disorder. Taylor & Francis, London
101. Limberg A, Barnow S, Freyberger HJ, Hamm AO (2011) Emotional vulnerability in borderline personality disorder is cue specific and modulated by traumatization. Biol Psychiatry 69(6):574-582
102. Sergerie K, Chochol C, Armony JL (2008) The role of the amygdala in emotional processing: a quantitative meta-analysis of functional neuroimaging studies. Neurosci Biobehav Rev 32(4):811-830
103. Herwig U, Baumgartner T, Kaffenberger T, Brühl A, Kottlow M, Schreiter-Gasser U, Abler B, Jäncke L, Rufer M (2007) Modulation of anticipatory emotion and perception processing by cognitive control. Neuroimage 37(2):652-662
104. Windischberger C, Lanzenberger R, Holik A, Spindelegger C, Stein P, Moser U, Gerstl F, Fink M, Moser E, Kasper S (2010) Area-specific modulation of neural activation comparing escitalopram and citalopram revealed by pharmaco-fMRI: a randomized cross-over study. Neuroimage 49(2):1161-1170
105. Braams BR, Blechert J, Boden MT, Gross JJ (2012) The effects of acceptance and suppression on anticipation and receipt of painful stimulation. J Behav Ther Exp Psychiatry 43(4):1014-1018
106. Vuilleumier P, Richardson MP, Armony JL, Driver J, Dolan RJ (2004) Distant influences of amygdala lesion on visual cortical activation during emotional face processing. Nat Neurosci 7(11):1271-1278