Mg supplementation protects against ritonavir-mediated endothelial oxidative stress and hepatic eNOS downregulation

Free Radical Biology and Medicine

Volumn 69, Issue , 2014, Pages 77-85

  Chen, Xi ^a   Mak, I Tong ^a  

^a GEORGE WASHINGTON UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

Decreased eNOS dimer monomer ratio; Decreased plasma nitrite; Endothelial cell oxidative stress; Free radicals; Mg supplementation; Plasma 8 isoprostane; Protease inhibitor ritonavir; Rat hepatic eNOS downregulation

Indexed keywords

8 ISOPROSTANE; DIMER; ENDOTHELIAL NITRIC OXIDE SYNTHASE; GLUTATHIONE; GLUTATHIONE DISULFIDE; MAGNESIUM; MESSENGER RNA; MONOMER; NITRIC OXIDE; REACTIVE OXYGEN METABOLITE; RITONAVIR; SUPEROXIDE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CATTLE; CELL COUNT; CELL CULTURE; CELL DEATH; CELL GROWTH; CELL VIABILITY; CONTROLLED STUDY; CYTOTOXICITY; DOWN REGULATION; ENDOTHELIUM CELL; FLOW CYTOMETRY; LIVER PROTECTION; LIVER TOXICITY; MALE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; RAT; SUPPLEMENTATION; WESTERN BLOTTING;

DECREASED ENOS DIMER/MONOMER RATIO; DECREASED PLASMA NITRITE; ENDOTHELIAL CELL OXIDATIVE STRESS; FREE RADICALS; MG SUPPLEMENTATION; PLASMA 8-ISOPROSTANE; PROTEASE INHIBITOR RITONAVIR; RAT HEPATIC ENOS DOWNREGULATION;

ANIMALS; ANTI-HIV AGENTS; CATTLE; CELLS, CULTURED; CORONARY VESSELS; DIETARY SUPPLEMENTS; ENDOTHELIAL CELLS; LIVER; MAGNESIUM; NITRIC OXIDE; NITRIC OXIDE SYNTHASE TYPE III; OXIDATIVE STRESS; RATS; RITONAVIR;

EID: 84893241993     PISSN: 08915849     EISSN: 18734596     Source Type: Journal    
DOI: 10.1016/j.freeradbiomed.2014.01.011     Document Type: Article

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