Targeted transferrin-modified polymeric micelles: Enhanced efficacy in vitro and in vivo in ovarian carcinoma

Molecular Pharmaceutics

Volumn 11, Issue 2, 2014, Pages 375-381

  Sawant, Rupa R ^a   Jhaveri, Aditi M ^a   Koshkaryev, Alexander ^a   Zhu, Lin ^a   Qureshi, Farooq ^b   Torchilin, Vladimir P ^a  

^a NORTHEASTERN UNIVERSITY   (United States)

^b HOFFMANN LA ROCHE INC   (United States)

Author keywords

cancer; drug delivery; polymeric micelles; targeted; transferrin

Indexed keywords

CYCLIN DEPENDENT KINASE INHIBITOR; LIPID; TRANSFERRIN; (4-AMINO-2-(1-METHANESULFONYLPIPERIDIN-4-YLAMINO)PYRIMIDIN-5-YL)(2,3-DIFLUORO-6-METHOXYPHENYL)METHANONE; ANTINEOPLASTIC AGENT; MICELLE; PYRIMIDINE DERIVATIVE; WATER;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CANCER INHIBITION; CARCINOMA CELL; CYTOTOXICITY; DRUG SOLUTION; ENDOCYTOSIS; IN VITRO STUDY; IN VIVO STUDY; MICELLE; MOUSE; NONHUMAN; OVARY CARCINOMA; POLYMERIZATION; PRIORITY JOURNAL; ANIMAL; CHEMISTRY; CONFOCAL MICROSCOPY; DRUG DELIVERY SYSTEM; FEMALE; FLOW CYTOMETRY; HUMAN; METABOLISM; NEOPLASMS, GLANDULAR AND EPITHELIAL; OVARIAN NEOPLASMS; SOLUBILITY; TUMOR CELL LINE;

ANIMALS; ANTINEOPLASTIC AGENTS; CELL LINE, TUMOR; DRUG DELIVERY SYSTEMS; FEMALE; FLOW CYTOMETRY; HUMANS; MICE; MICELLES; MICROSCOPY, CONFOCAL; NEOPLASMS, GLANDULAR AND EPITHELIAL; OVARIAN NEOPLASMS; PYRIMIDINES; SOLUBILITY; TRANSFERRIN; WATER;

EID: 84893220538     PISSN: 15438384     EISSN: 15438392     Source Type: Journal    
DOI: 10.1021/mp300633f     Document Type: Article

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