Vitamin C prevents cigarette smoke-induced pulmonary emphysema in mice and provides pulmonary restoration

American Journal of Respiratory Cell and Molecular Biology

Volumn 50, Issue 2, 2014, Pages 347-357

  Koike, Kengo ^a   Ishigami, Akihito ^b   Sato, Yasunori ^b   Hirai, Toyohiro ^c   Yuan, Yiming ^d   Kobayashi, Etsuko ^a   Tobino, Kazunori ^a   Sato, Tadashi ^a   Sekiya, Mitsuaki ^a   Takahashi, Kazuhisa ^a   Fukuchi, Yoshinosuke ^a   Maruyama, Naoki ^b   Seyama, Kuniaki ^a  

^a JUNTENDO UNIVERSITY   (Japan)

^b TOKYO METROPOLITAN INSTITUTE OF GERONTOLOGY   (Japan)

^c KYOTO UNIVERSITY   (Japan)

^d SICHUAN UNIVERSITY   (China)

Author keywords

Chronic obstructive pulmonary disease; Oxidative stress; Senescence marker protein 30; Vascular endothelial growth factor

Indexed keywords

ASCORBIC ACID; CIGARETTE SMOKE; GLUTATHIONE PEROXIDASE; KI 67 ANTIGEN; REACTIVE OXYGEN METABOLITE; REGUCALCIN; TUMOR NECROSIS FACTOR ALPHA; VASCULOTROPIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BODY WEIGHT; CELL COUNT; CELL POPULATION; CELL PROLIFERATION; CIGARETTE SMOKE-INDUCED EMPHYSEMA; COLLAGEN SYNTHESIS; CONTROLLED STUDY; DRUG TISSUE LEVEL; ENZYME ACTIVITY; IMMUNOHISTOCHEMISTRY; LONG TERM EXPOSURE; LUNG COMPLIANCE; LUNG HOMOGENATE; LUNG LAVAGE; LUNG PARENCHYMA; LUNG PRESSURE; LUNG VOLUME; MORPHOMETRICS; MOUSE; NONHUMAN; OXIDATIVE STRESS; PNEUMONIA; PREVENTION STUDY; PULMONARY RESTORATION; SMOKING CESSATION; TISSUE REGENERATION; TREATMENT OUTCOME;

ANIMALS; ASCORBIC ACID; CALCIUM-BINDING PROTEINS; DISEASE MODELS, ANIMAL; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MICE; MICE, KNOCKOUT; OXIDATIVE STRESS; PULMONARY DISEASE, CHRONIC OBSTRUCTIVE; PULMONARY EMPHYSEMA; SMOKE; TOBACCO;

EID: 84893210918     PISSN: 10441549     EISSN: 15354989     Source Type: Journal    
DOI: 10.1165/rcmb.2013-0121OC     Document Type: Article

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