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Volumn 8, Issue 1, 2014, Pages

Influence networks based on coexpression improve drug target discovery for the development of novel cancer therapeutics

Author keywords

Breast cancer; Coexpression networks; Drug target discovery; Letrozole; Tumor adaptation

Indexed keywords

ANTINEOPLASTIC AGENT; ESTROGEN RECEPTOR; LETROZOLE; MESSENGER RNA; NITRILE; TRIAZOLE DERIVATIVE;

EID: 84893196547     PISSN: None     EISSN: 17520509     Source Type: Journal    
DOI: 10.1186/1752-0509-8-12     Document Type: Article
Times cited : (11)

References (34)
  • 1
    • 33846995628 scopus 로고    scopus 로고
    • Economics of new oncology drug development
    • 10.1200/JCO.2006.09.0803, 17210942
    • DiMasi JA, Grabowski HG. Economics of new oncology drug development. J Clin Oncol 2007, 25(2):209-216. 10.1200/JCO.2006.09.0803, 17210942.
    • (2007) J Clin Oncol , vol.25 , Issue.2 , pp. 209-216
    • DiMasi, J.A.1    Grabowski, H.G.2
  • 2
    • 4344645978 scopus 로고    scopus 로고
    • Can the pharmaceutical industry reduce attrition rates?
    • 10.1038/nrd1470, 15286737
    • Kola I, Landis J. Can the pharmaceutical industry reduce attrition rates?. Nat Rev Drug Discov 2004, 3(8):711-716. 10.1038/nrd1470, 15286737.
    • (2004) Nat Rev Drug Discov , vol.3 , Issue.8 , pp. 711-716
    • Kola, I.1    Landis, J.2
  • 3
    • 58149186582 scopus 로고    scopus 로고
    • Do molecularly targeted agents in oncology have reduced attrition rates?
    • Walker I, Newell H. Do molecularly targeted agents in oncology have reduced attrition rates?. Nat Rev Drug Discov 2008, 8:15-16.
    • (2008) Nat Rev Drug Discov , vol.8 , pp. 15-16
    • Walker, I.1    Newell, H.2
  • 4
    • 0742305866 scopus 로고    scopus 로고
    • Network biology: understanding the cell's functional organization
    • 10.1038/nrg1272, 14735121
    • Barabási A, Oltvai Z. Network biology: understanding the cell's functional organization. Nat Rev Genet 2004, 5:101-113. 10.1038/nrg1272, 14735121.
    • (2004) Nat Rev Genet , vol.5 , pp. 101-113
    • Barabási, A.1    Oltvai, Z.2
  • 5
    • 34247622363 scopus 로고    scopus 로고
    • The importance of bottlenecks in protein networks: correlation with gene essentiality and expression dynamics
    • Yu H, et al. The importance of bottlenecks in protein networks: correlation with gene essentiality and expression dynamics. PLoS Comput Biol 2007, 3:0713-0720.
    • (2007) PLoS Comput Biol , vol.3 , pp. 713-720
    • Yu, H.1
  • 7
    • 84856227277 scopus 로고    scopus 로고
    • Sequential changes in gene expression profiles in breast cancers during treatment with the aromatase inhibitor, letrozole
    • 10.1038/tpj.2010.67, 20697427
    • Miller W, Larionov A, Anderson T, Evans D, Dixon J. Sequential changes in gene expression profiles in breast cancers during treatment with the aromatase inhibitor, letrozole. Pharmacogenomics J 2012, 12:10-21. 10.1038/tpj.2010.67, 20697427.
    • (2012) Pharmacogenomics J , vol.12 , pp. 10-21
    • Miller, W.1    Larionov, A.2    Anderson, T.3    Evans, D.4    Dixon, J.5
  • 8
    • 29144535372 scopus 로고    scopus 로고
    • Evolving gene/transcript definitions significantly alter the interpretation of GeneChip data
    • 10.1093/nar/gni179, 1283542, 16284200
    • Dai M, Wang P, Boyd A, Kostov G, Athey B, Jones E, Bunney W, Myers R, Speed T, Akil H, et al. Evolving gene/transcript definitions significantly alter the interpretation of GeneChip data. Nucleic Acids Res 2005, 33(20):e175-e175. 10.1093/nar/gni179, 1283542, 16284200.
    • (2005) Nucleic Acids Res , vol.33 , Issue.20
    • Dai, M.1    Wang, P.2    Boyd, A.3    Kostov, G.4    Athey, B.5    Jones, E.6    Bunney, W.7    Myers, R.8    Speed, T.9    Akil, H.10
  • 9
    • 0142121516 scopus 로고    scopus 로고
    • Exploration, normalization, and summaries of high density oligonucleotide array probe level data
    • 10.1093/biostatistics/4.2.249, 12925520
    • Irizarry R, Hobbs B, Collin F, Beazer-Barclay Y, Antonellis K, Scherf U, Speed T. Exploration, normalization, and summaries of high density oligonucleotide array probe level data. Biostatistics 2003, 4(2):249-264. 10.1093/biostatistics/4.2.249, 12925520.
    • (2003) Biostatistics , vol.4 , Issue.2 , pp. 249-264
    • Irizarry, R.1    Hobbs, B.2    Collin, F.3    Beazer-Barclay, Y.4    Antonellis, K.5    Scherf, U.6    Speed, T.7
  • 10
    • 33746768303 scopus 로고    scopus 로고
    • Springer New York, Smyth, G: limma: Linear Models for Microarray Data. In Bioinformatics and Computational Biology Solutions Using R and Bioconductor. Edited by Gentleman R, Carey VJ, Huber W, Irizarry RA, Dudoit S. New York: Springer; 2005: 397-420.
    • Smyth G. limma: Linear Models for Microarray Data 2005, 397-420, Springer New York, Smyth, G: limma: Linear Models for Microarray Data. In Bioinformatics and Computational Biology Solutions Using R and Bioconductor. Edited by Gentleman R, Carey VJ, Huber W, Irizarry RA, Dudoit S. New York: Springer; 2005: 397-420.
    • (2005) limma: Linear Models for Microarray Data
    • Smyth, G.1
  • 11
    • 33747344944 scopus 로고    scopus 로고
    • Comparison and evaluation of methods for generating differentially expressed gene lists from microarray data
    • 10.1186/1471-2105-7-359, 1544358, 16872483
    • Jeffery I, Higgins D, Culhane A. Comparison and evaluation of methods for generating differentially expressed gene lists from microarray data. BMC Bioinformatics 2006, 7:359. 10.1186/1471-2105-7-359, 1544358, 16872483.
    • (2006) BMC Bioinformatics , vol.7 , pp. 359
    • Jeffery, I.1    Higgins, D.2    Culhane, A.3
  • 12
    • 12344321571 scopus 로고    scopus 로고
    • Discovery of meaningful associations in genomic data using partial correlation coefficients
    • 10.1093/bioinformatics/bth445, 15284096
    • de la Fuente A, Bing N, Hoeschele I, Mendes P. Discovery of meaningful associations in genomic data using partial correlation coefficients. Bioinformatics 2004, 20(18):3565-3574. 10.1093/bioinformatics/bth445, 15284096.
    • (2004) Bioinformatics , vol.20 , Issue.18 , pp. 3565-3574
    • de la Fuente, A.1    Bing, N.2    Hoeschele, I.3    Mendes, P.4
  • 13
    • 43349094507 scopus 로고    scopus 로고
    • The igraph software package for complex network research
    • Complex Systems
    • Csardi G, Nepusz T. The igraph software package for complex network research. InterJournal 2006, Complex Systems:1695. [http://igraph.sf.net].
    • (2006) InterJournal , pp. 1695
    • Csardi, G.1    Nepusz, T.2
  • 15
    • 84862195351 scopus 로고    scopus 로고
    • COLT-Cancer: functional genetic screening resource for essential genes in human cancer cell lines
    • 10.1093/nar/gkr959, 3245009, 22102578
    • Koh JL, Brown KR, Sayad A, Kasimer D, Ketela T, Moffat J. COLT-Cancer: functional genetic screening resource for essential genes in human cancer cell lines. Nucleic Acids Res 2012, 40(D1):D957-D963. 10.1093/nar/gkr959, 3245009, 22102578.
    • (2012) Nucleic Acids Res , vol.40 , Issue.D1
    • Koh, J.L.1    Brown, K.R.2    Sayad, A.3    Kasimer, D.4    Ketela, T.5    Moffat, J.6
  • 17
    • 84877357986 scopus 로고    scopus 로고
    • Key genes for modulating information flow play a temporal role as breast tumor coexpression networks are dynamically rewired by letrozole
    • Penrod NM, Moore JH. Key genes for modulating information flow play a temporal role as breast tumor coexpression networks are dynamically rewired by letrozole. BMC Med Genomics 2013, 6(Suppl 2):S2.
    • (2013) BMC Med Genomics , vol.6 , Issue.SUPPL. 2
    • Penrod, N.M.1    Moore, J.H.2
  • 18
    • 79960835665 scopus 로고    scopus 로고
    • TMEM14A inhibits N-(4-hydroxyphenyl) retinamide-induced apoptosis through the stabilization of mitochondrial membrane potential
    • 10.1016/j.canlet.2011.05.031, 21723035
    • Woo IS, Jin H, Kang ES, Kim HJ, Lee JH, Chang KC, Park JY, Choi WS, Seo HG. TMEM14A inhibits N-(4-hydroxyphenyl) retinamide-induced apoptosis through the stabilization of mitochondrial membrane potential. Cancer Lett 2011, 309(2):190-198. 10.1016/j.canlet.2011.05.031, 21723035.
    • (2011) Cancer Lett , vol.309 , Issue.2 , pp. 190-198
    • Woo, I.S.1    Jin, H.2    Kang, E.S.3    Kim, H.J.4    Lee, J.H.5    Chang, K.C.6    Park, J.Y.7    Choi, W.S.8    Seo, H.G.9
  • 19
    • 84893866572 scopus 로고    scopus 로고
    • Regulation of planar cell polarity and Vangl2 trafficking by Tmem14a
    • University of Toronto 2012
    • Chea E. Regulation of planar cell polarity and Vangl2 trafficking by Tmem14a. Master's thesis, University of Toronto 2012.
    • Master's thesis,
    • Chea, E.1
  • 20
    • 72049111230 scopus 로고    scopus 로고
    • The planar cell polarity protein Van Gogh-Like 2 regulates tumor cell migration and matrix metalloproteinase-dependent invasion
    • 10.1016/j.canlet.2009.05.041, 19577357
    • Cantrell VA, Jessen JR. The planar cell polarity protein Van Gogh-Like 2 regulates tumor cell migration and matrix metalloproteinase-dependent invasion. Cancer Lett 2010, 287:54-61. 10.1016/j.canlet.2009.05.041, 19577357.
    • (2010) Cancer Lett , vol.287 , pp. 54-61
    • Cantrell, V.A.1    Jessen, J.R.2
  • 21
    • 80052658935 scopus 로고    scopus 로고
    • A single nucleotide polymorphism-derived regulatory gene network underlying puberty in 2 tropical breeds of beef cattle
    • 10.2527/jas.2010-3681, 21357453
    • Fortes M, Reverter A, Nagaraj S, Zhang Y, Jonsson N, Barris W, Lehnert S, Boe-Hansen G, Hawken R. A single nucleotide polymorphism-derived regulatory gene network underlying puberty in 2 tropical breeds of beef cattle. J Anim Sci 2011, 89:1669-1683. 10.2527/jas.2010-3681, 21357453.
    • (2011) J Anim Sci , vol.89 , pp. 1669-1683
    • Fortes, M.1    Reverter, A.2    Nagaraj, S.3    Zhang, Y.4    Jonsson, N.5    Barris, W.6    Lehnert, S.7    Boe-Hansen, G.8    Hawken, R.9
  • 22
    • 33748344952 scopus 로고    scopus 로고
    • A homeodomain-zinc finger protein, ZFHX4, is expressed in neuronal differentiation manner and suppressed in muscle differentiation manner
    • 10.1248/bpb.29.1830, 16946494
    • Hemmi K, Ma D, Miura Y, Kawaguchi M, Sasahara M, Hashimoto-Tamaoki T, Tamaoki T, Sakata N, Tsuchiya K. A homeodomain-zinc finger protein, ZFHX4, is expressed in neuronal differentiation manner and suppressed in muscle differentiation manner. Biol Pharm Bull 2006, 29:1830-1835. 10.1248/bpb.29.1830, 16946494.
    • (2006) Biol Pharm Bull , vol.29 , pp. 1830-1835
    • Hemmi, K.1    Ma, D.2    Miura, Y.3    Kawaguchi, M.4    Sasahara, M.5    Hashimoto-Tamaoki, T.6    Tamaoki, T.7    Sakata, N.8    Tsuchiya, K.9
  • 26
    • 4644326931 scopus 로고    scopus 로고
    • Genomic analysis of regulatory network dynamics reveals large topological changes
    • 10.1038/nature02782, 15372033
    • Luscombe NM, Babu MM, Yu H, Snyder M, Teichmann SA, Gerstein M. Genomic analysis of regulatory network dynamics reveals large topological changes. Nature 2004, 431(7006):308-312. 10.1038/nature02782, 15372033.
    • (2004) Nature , vol.431 , Issue.7006 , pp. 308-312
    • Luscombe, N.M.1    Babu, M.M.2    Yu, H.3    Snyder, M.4    Teichmann, S.A.5    Gerstein, M.6
  • 28
    • 84880562927 scopus 로고    scopus 로고
    • Genome-wide generation and systematic phenotyping of knockout mice reveals new roles for many genes
    • 10.1016/j.cell.2013.06.022, 3717207, 23870131
    • White JK, Gerdin AK, Karp NA, Ryder E, Buljan M, Bussell JN, Salisbury J, Clare S, Ingham NJ, Podrini C, et al. Genome-wide generation and systematic phenotyping of knockout mice reveals new roles for many genes. Cell 2013, 154(2):452-464. 10.1016/j.cell.2013.06.022, 3717207, 23870131.
    • (2013) Cell , vol.154 , Issue.2 , pp. 452-464
    • White, J.K.1    Gerdin, A.K.2    Karp, N.A.3    Ryder, E.4    Buljan, M.5    Bussell, J.N.6    Salisbury, J.7    Clare, S.8    Ingham, N.J.9    Podrini, C.10
  • 29
    • 79952284127 scopus 로고    scopus 로고
    • Hallmarks of cancer: the next generation
    • 10.1016/j.cell.2011.02.013, 21376230
    • Hanahan D, Weinberg RA. Hallmarks of cancer: the next generation. Cell 2011, 144(5):646-674. 10.1016/j.cell.2011.02.013, 21376230.
    • (2011) Cell , vol.144 , Issue.5 , pp. 646-674
    • Hanahan, D.1    Weinberg, R.A.2
  • 30
    • 79953283356 scopus 로고    scopus 로고
    • Genetic interactions in cancer progression and treatment
    • 10.1016/j.cell.2011.03.020, 21458666
    • Ashworth A, Lord C, Reis-Filho J. Genetic interactions in cancer progression and treatment. Cell 2011, 145:30-38. 10.1016/j.cell.2011.03.020, 21458666.
    • (2011) Cell , vol.145 , pp. 30-38
    • Ashworth, A.1    Lord, C.2    Reis-Filho, J.3
  • 31
    • 41449115982 scopus 로고    scopus 로고
    • Neoadjuvant letrozole in postmenopausal estrogen and/or progesterone receptor positive breast cancer: a phase IIb/III trial to investigate optimal duration of preoperative endocrine therapy
    • 10.1186/1471-2407-8-62, 2270851, 18302747
    • Krainick-Strobel UE, Lichtenegger W, Wallwiener D, Tulusan AH, Jänicke F, Bastert G, Kiesel L, Wackwitz B, Paepke S. Neoadjuvant letrozole in postmenopausal estrogen and/or progesterone receptor positive breast cancer: a phase IIb/III trial to investigate optimal duration of preoperative endocrine therapy. BMC Cancer 2008, 8:62. 10.1186/1471-2407-8-62, 2270851, 18302747.
    • (2008) BMC Cancer , vol.8 , pp. 62
    • Krainick-Strobel, U.E.1    Lichtenegger, W.2    Wallwiener, D.3    Tulusan, A.H.4    Jänicke, F.5    Bastert, G.6    Kiesel, L.7    Wackwitz, B.8    Paepke, S.9
  • 32
    • 84860779793 scopus 로고    scopus 로고
    • Phase II trial with letrozole to maximum response as primary systemic therapy in postmenopausal patients with ER/PgR [+] operable breast cancer
    • 10.1007/s12094-012-0771-9, 22301401
    • Llombart-Cussac A, Guerrero T, Galán A, Carañana V, Buch E, Rodríguez-Lescure T, Ruiz A, Fuster Diana C, Guillem Porta V. Phase II trial with letrozole to maximum response as primary systemic therapy in postmenopausal patients with ER/PgR [+] operable breast cancer. Clin Transl Oncol 2012, 14(2):125-131. 10.1007/s12094-012-0771-9, 22301401.
    • (2012) Clin Transl Oncol , vol.14 , Issue.2 , pp. 125-131
    • Llombart-Cussac, A.1    Guerrero, T.2    Galán, A.3    Carañana, V.4    Buch, E.5    Rodríguez-Lescure, T.6    Ruiz, A.7    Fuster Diana, C.8    Guillem Porta, V.9
  • 33
    • 84877010367 scopus 로고    scopus 로고
    • Increased pathological complete response rate after a long-term neoadjuvant letrozole treatment in postmenopausal oestrogen and/or progesterone receptor-positive breast cancer
    • 10.1038/bjc.2013.151, 23579222
    • Allevi G, Strina C, Andreis D, Zanoni V, Bazzola L, Bonardi S, Foroni C, Milani M, Cappelletti M, Gussago F, et al. Increased pathological complete response rate after a long-term neoadjuvant letrozole treatment in postmenopausal oestrogen and/or progesterone receptor-positive breast cancer. Br J Cancer 2013, 108(8):1587-1592. 10.1038/bjc.2013.151, 23579222.
    • (2013) Br J Cancer , vol.108 , Issue.8 , pp. 1587-1592
    • Allevi, G.1    Strina, C.2    Andreis, D.3    Zanoni, V.4    Bazzola, L.5    Bonardi, S.6    Foroni, C.7    Milani, M.8    Cappelletti, M.9    Gussago, F.10
  • 34
    • 58049191344 scopus 로고    scopus 로고
    • Increase in response rate by prolonged treatment with neoadjuvant letrozole
    • 10.1007/s10549-008-9915-6, 18264759
    • Dixon J, et al. Increase in response rate by prolonged treatment with neoadjuvant letrozole. Breast Cancer Res Treat 2009, 113:145-151. 10.1007/s10549-008-9915-6, 18264759.
    • (2009) Breast Cancer Res Treat , vol.113 , pp. 145-151
    • Dixon, J.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.