Multifunctional superparamagnetic Fe3O4@SiO 2 core/shell nanoparticles: Design and application for cell imaging

Journal of Biomedical Nanotechnology

Volumn 10, Issue 2, 2014, Pages 262-270

  Zhao, Xueling ^a   Zhao, Hongli ^a   Yuan, Huihui ^a   Lan, Minbo ^a,b  

^a EAST CHINA UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

^b East China University of Science and Technology   (China)

Author keywords

Biocompatible; Cell imaging; Core Shell; Magnetic nanoparticles; Multifunctional

Indexed keywords

BIOCOMPATIBLE; CELL IMAGING; CORE/SHELL; MAGNETIC NANO-PARTICLES; MULTIFUNCTIONAL;

BIOCOMPATIBILITY; DYNAMIC LIGHT SCATTERING; FLUORESCENCE SPECTROSCOPY; INFRARED SPECTROSCOPY; MICROEMULSIONS; NANOPARTICLES; POLYETHYLENE GLYCOLS; SUPERPARAMAGNETISM; THERMOGRAVIMETRIC ANALYSIS; TRANSMISSION ELECTRON MICROSCOPY; X RAY DIFFRACTION;

SYNTHESIS (CHEMICAL);

3 (4,5 DIMETHYL 2 THIAZOLYL) 2,5 DIPHENYLTETRAZOLIUM BROMIDE; FOLATE RECEPTOR; MACROGOL; MULTIFUNCTIONAL NANOMATERIAL; MULTIFUNCTIONAL SUPERPARAMAGNETIC IRON OXIDE CORE SHELL NANOPARTICLE; NANOCOMPOSITE; NANOMATERIAL; SILICATE; SILICON DIOXIDE; SUPERPARAMAGNETIC IRON OXIDE NANOPARTICLE; UNCLASSIFIED DRUG; FOLIC ACID; MAGNETITE NANOPARTICLE;

ARTICLE; CANCER CELL; CELL LABELING; CELL VIABILITY; CONFOCAL LASER MICROSCOPY; CONJUGATE; CONTROLLED STUDY; CYTOTOXICITY; FLUORESCENCE SPECTROSCOPY; HUMAN; HUMAN CELL; IMAGING; INFRARED SPECTROSCOPY; LIGHT SCATTERING; MICROEMULSION; PARTICLE SIZE; SYNTHESIS; THERMOGRAVIMETRY; TRANSMISSION ELECTRON MICROSCOPY; X RAY POWDER DIFFRACTION; ANIMAL; CELL DEATH; CELL STRAIN 3T3; CHEMISTRY; DRUG EFFECT; ENDOCYTOSIS; METHODOLOGY; MOLECULAR IMAGING; MOUSE; POWDER; SPECTROFLUOROMETRY; SURFACE PROPERTY; TUMOR CELL LINE; ULTRASTRUCTURE; ULTRAVIOLET SPECTROPHOTOMETRY; X RAY DIFFRACTION;

ANIMALS; CELL DEATH; CELL LINE, TUMOR; ENDOCYTOSIS; FOLIC ACID; HUMANS; MAGNETITE NANOPARTICLES; MICE; MOLECULAR IMAGING; NIH 3T3 CELLS; PARTICLE SIZE; POWDERS; SILICON DIOXIDE; SPECTROMETRY, FLUORESCENCE; SPECTROPHOTOMETRY, ULTRAVIOLET; SPECTROSCOPY, FOURIER TRANSFORM INFRARED; SURFACE PROPERTIES; THERMOGRAVIMETRY; X-RAY DIFFRACTION;

EID: 84893167640     PISSN: 15507033     EISSN: 15507041     Source Type: Journal    
DOI: 10.1166/jbn.2014.1641     Document Type: Article

References (42)

1. J. Cheon and J. H. Lee, Synergistically integrated nanoparticles as multimodal probes for nanobiotechnology. Acc. Chem. Res. 41, 1630 (2008).
2. R. R. Qiao, C. H. Yang, and M. Y. Gao, Superparamagnetic iron oxide nanoparticles: From preparations to in vivo MRI applications. J. Mater. Chem. 19, 6274 (2009).
3. H. C. Lu, G. S. Yi, S. Y. Zhao, D. Chen, L. H. Guo, and J. Cheng, Synthesis and characterization of multifunctional nanoparticles possessing magnetic, up-conversion fluorescence and bio-affinity properties. J. Mater. Chem. 14, 1336 (2004).
4. J. H. Gao, H. W. Gu, and B. Xu, Multifunctional magnetic nanoparticles: Design, synthesis, and biomedical applications. Acc. Chem. Res. 42, 1097 (2009).
5. M. Q. Wang, J. X. Zhang, Z. M. Yuan, W. Z. Yang, Q. Wu, and H. C. Gu, Targeted thrombolysis by using of magnetic mesoporous silica nanoparticles. J. Biomed. Nanotechnol. 8, 624 (2012).
6. C. H. Cunningham, T. Arai, P. C. Yang, M. V. McConnell, J. M. Pauly, and S. M. Conolly, Positive contrast magnetic resonance imaging of cells labeled with magnetic nanoparticles. Magn. Reson. Med. 53, 999 (2005).
7. P. Tallury, S. Santra, P. Sharma, B. Maria, D. C. Matos, N. Bengtsson, S. Biswas, A. K. Saha, G. A. Walter, E. A. Scott, and B. M. Moudgil, Fluorescent and paramagnetic chitosan nanoparticles that exhibit high magnetic resonance relaxivity: Synthesis, Characterization and In vitro studies. J. Biomed. Nanotechnol. 7, 724 (2011).
8. B. Polyak and G. Friedman, Magnetic targeting for site-specific drug delivery: Applications and clinical potential. Expert. Opin. Drug Del. 6, 53 (2009).
9. M. Kawashita, K. Kawamura, and Z. Li, PMMA-based bone cements containing magnetite particles for the hyperthermia of cancer. Acta Biomater. 6, 3187 (2010).
10. K. J. Widder, A. E. Senyei, and D. F. Ranney, In vitro release of biologically active adriamycin by magnetically responsive albumin microspheres. Cancer Res. 40, 3512 (1980).
11. Y. Lu, Y. D. Yin, B. T. Mayers, and Y. N. Xia, Modifying the surface properties of superparamagnetic iron oxide nanoparticles through a sol-gel approach. Nano Lett. 2, 183 (2002).
12. H. H. Yang, S. Q. Zhang, X. L. Chen, Z. X. Zhuang, J. G. Xu, and X. R. Wang, Magnetite-containing spherical silica nanoparticles for biocatalysis and bioseparations. Anal. Chem. 76, 1316 (2004).
13. Y. A. Barnakov, M. H. Yu, and Z. Rosenzweig, Manipulation of the magnetic properties of magnetite-silica nanocomposite materials by controlled stober synthesis. Langmuir 21, 7524 (2005).
14. R. He, X. G. You, J. Shao, F. Gao, B. Pan, and D. X. Cui, Core/shell fluorescent magnetic silica-coated composite nanoparticles for bioconjugation. Nanotechnology 18, 315601 (2007).
15. W. Lai, J. Garino, and P. Ducheyne, Silicon excretion from bioactive glass implanted in rabbit bone. Biomaterials 23, 213 (2002).
16. 2 nanocomposites: Enabling the tuning of both the iron oxide load and the size of the nanoparticles. Langmuir 24, 3532 (2008).
17. T. J. Yoon, K. N. Yu, E. Kim, J. S. Kim, B. G. Kim, S. H. Yun, B. H. Sohn, M. H. Cho, J. K. Lee, and S. B. Park, Specific targeting, cell sorting, and bioimaging with smart magnetic silica core-shell nanomaterials. Small 2, 209 (2006).
18. H. Yang, Y. M. Zhuang, H. Hu, X. X. Du, C. X. Zhang, X. Y. Shi, H. X. Wu, and S. P. Yang, Silica-coated manganese oxide nanoparticles as a platform for targeted magnetic resonance and fluorescence imaging of cancer cells. Adv. Funct. Mater. 20, 1733 (2010).
19. B. B. Zhang, B. D. Chen, Y. L. Wang, F. F. Guo, Z. Q. Li, and D. L. Shi, Preparation of highly fluorescent magnetic nanoparticles for analytes-enrichment and subsequent biodetection. J. Colloid Interface Sci. 353, 426 (2011).
20. X. X. Wang, J. Y. Zhong, Y. Liu, A. X. Wen, Z. Shan, and W. S. Yang, Preparation of magnetic and fluorescent bifunctional nanocomposites and its application to separation and detection of glucose. Acta Chim. Sinica 20, 2063 (2010).
21. C. W. Lu, Y. Hung, J. K. Hsiao, M. Yao, T. H. Chung, Y. S. Lin, S. H. Wu, S. C. Hsu, H. M. Liu, C. Y. Mou, C. S. Yang, D. M. Huang, and Y. C. Chen, Bifunctional magnetic silica nanoparticles for highly efficient human stem cell labeling. Nano Lett. 7, 149 (2007).
22. 4 nanoparticles to a GMR biosensor agent for single molecular detection. J. Nanosci. Nanotechnol. 11, 82 (2011).
23. W. Schartl, Current directions in core-shell nanoparticle design. Nanoscale 2, 829 (2010).
24. X. J. Zhao, R. P. Bagwe, and W. H. Tan, Development of organicdye- doped silica nanoparticles in a reverse microemulsion. Adv. Mater. 16, 173 (2004).
25. S. Santra, P. Zhang, K. Wang, R. Tapec, and W. H. Tan, Conjugation of biomolecules with luminophore-doped silica nanoparticles for photostable biomarkers. Anal. Chem. 73, 4988 (2001).
26. 2-weighted MRI contrast agent: Highly reproducible synthesis of uniform single-loaded core-shell nanostructures. Chem. Asian J. 4, 1809 (2009).
27. X. Q. Yang, J. J. Grailer, I. J. Rowland, A. Javadi, S. A. Hurley, D. A. Steeber, and S. Q. Gong, Multifunctional SPIO/DOX-loaded wormlike polymer vesicles for cancer therapy and MR imaging. Biomaterials 31, 9065 (2010).
28. Y. Geng and D. E. Discher, Hydrolytic degradation of poly(ethylene oxide)-block-polycaprolactone worm micelles. J. Am. Chem. Soc. 127, 12780 (2005).
29. A. J. Cole, A. E. David, J. X. Wang, C. J. Galban, H. L. Hill, and V. C. Yang, Polyethylene glycol modified, cross-linked starch-coated iron oxide nanoparticles for enhanced magnetic tumor targeting. Biomaterials 32, 2183 (2011).
30. S. Sun and H. Zeng, Size-controlled synthesis of magnetite nanoparticles. J. Am. Chem. Soc. 124, 8204 (2002).
31. F. Ni, L. Jiang, R. X. Yang, Z. P. Chen, X. Qi, and J. W. Wang, Effects of PEG length and iron oxide nanoparticles size on reduced protein adsorption and non-specific uptake by macrophage cells. J. Nanosci. Nanotechnol. 12, 2094 (2012).
32. T. M. Allen, Long-circulating (sterically stabilized) liposomes for targeted drug-delivery. Trends Pharmacol. Sci. 15, 215 (1994).
33. X. X. He, H. L. Nie, K. Wang, W. H. Tan, X. Wu, and P. F. Zhang, In vivo study of biodistribution and urinary excretion of surface-modified silica nanoparticles. Anal. Chem. 80, 9597 (2008).
34. M. Wang and M. Thanou, Targeting nanoparticles to cancer. Pharmacol. Res. 62, 90 (2010).
35. R. B. Arote, S. K. Hwang, H. T. Lim, T. H. Kim, D. Jere, H. L. Jiang, Y. K. Kim, M. H. Cho, and C. S. Cho, The therapeutic efficiency of FP-PEA/TAM67 gene complexes via folate receptor-mediated endocytosis in a xenograft mice model. Biomaterials 31, 2435 (2010).
36. T. J. Chen, T. H. Cheng, Y. C. Hung, K. T. Lin, G. C. Liu, and Y. M. Wang, Targeted folic acid-PEG nanoparticles for noninvasive imaging of folate receptor by MRI. J. Biomed. Mater. Res. A 87, 165 (2008).
37. J. F. Ross, P. K. Chaudhuri, and M. Ratnam, Differential regulation of folate receptor isoforms in normal and malignant tissues in vivo and in established cell lines. Physiologic and clinical implications. Cancer 73, 2432 (1994).
38. C. Allen, N. D. Santos, R. Gallagher, GNC. Chiu, Y. Shu, W. M. Li, S. A. Johnstone, A. S. Janoff, L. D. Mayer, M. S. Webb, and M. B. Bally, Controlling the physical behavior and biological performance of liposome formulations through use of surface grafted poly(ethyleneglycol). Biosci. Rep. 22, 225 (2002).
39. X. T. Wen, J. X. Yang, B. He, and Z. W. Gu, Preparation of monodisperse magnetite nanoparticles under mild conditions. Curr. Appl. Phys. 8, 535 (2008).
40. 2 core/shell nanoparticles and their application for optical and magnetic resonance imaging. J. Mater. Chem. 22, 9253 (2012).
41. X. Q. Dong, Y. H. Zheng, Y. B. Huang, X. Chen, and X. B. Jing, Synthesis and characterization of multifunctional poly(glycidyl methacrylate) microspheres and their use in cell separation. Anal. Biochem. 405, 207 (2010).
42. M. K. Yoo, I. K. Park, H. T. Lim, S. J. Lee, H. L. Jiang, Y. K. Kim, Y. J. Choi, M. H. Cho and C. S. Cho, Folate-PEG-superparamagnetic iron oxide nanoparticles for lung cancer imaging. Acta Biomater. 8, 3005 (2012).