Multifunctional SPIO/DOX-loaded wormlike polymer vesicles for cancer therapy and MR imaging

Biomaterials

Volumn 31, Issue 34, 2010, Pages 9065-9073

  Yang, Xiaoqiang ^a   Grailer, Jamison J ^b   Rowland, Ian J ^c   Javadi, Alireza ^a   Hurley, Samuel A ^c   Steeber, Douglas A ^b   Gong, Shaoqin ^d  

^a University of Wisconsin Milwaukee   (United States)

^b UNIVERSITY OF WISCONSIN MILWAUKEE   (United States)

^c UNIVERSITY OF WISCONSIN SCHOOL OF MEDICINE AND PUBLIC HEALTH   (United States)

^d University of Wisconsin Madison   (United States)

Author keywords

Crosslinked inner hydrophilic layer; Targeted cancer therapy; Ultrasensitive MR imaging; Wormlike vesicles

Indexed keywords

ACRYLATE GROUPS; AMPHIPHILIC TRIBLOCK COPOLYMERS; ANTICANCER DRUG; CANCER THERAPY; CELLULAR UPTAKE; CLUSTERING EFFECT; CROSSLINKED; DOUBLE EMULSIONS; DOXORUBICIN; FOLATE RECEPTOR; HYDROPHOBIC MEMBRANE; IN-VIVO; LOADING LEVEL; MAGNETIC RESONANCE IMAGING CONTRAST AGENTS; METHOXY; MR IMAGING; PERSONALIZED MEDICINES; RELAXIVITY; SUPERPARAMAGNETIC IRON OXIDE NANOPARTICLES; TARGETED CANCER THERAPY; THERANOSTICS; TUMOR CELL LINES; ULTRASENSITIVE; WORM-LIKE POLYMERS; WORMLIKE VESICLES;

BLOCK COPOLYMERS; CELL CULTURE; DRUG THERAPY; EMULSIFICATION; FREE RADICAL POLYMERIZATION; FREE RADICALS; HYDROPHILICITY; HYDROPHOBICITY; IRON OXIDES; MOLECULAR BIOLOGY; NANOMAGNETICS; ONCOLOGY; POLYETHYLENE GLYCOLS; POLYETHYLENE OXIDES; POLYMERS; RESONANCE; SUPERPARAMAGNETISM; TUMORS;

MAGNETIC RESONANCE IMAGING;

COPOLYMER; DOXORUBICIN; FOLATE POLY(ETHYLENE GLYCOL) POLY(DEXTRO LEVO LACTIDE) POLY(ETHYLENE GLYCOL) ACRYLATE; FOLATE RECEPTOR; FREE RADICAL; NANOPARTICLE; SUPERPARAMAGNETIC IRON OXIDE; UNCLASSIFIED DRUG;

ARTICLE; CANCER THERAPY; CONTROLLED STUDY; CROSS LINKING; CYTOTOXICITY; DRUG STABILITY; EMULSION; ENCAPSULATION; ENDOCYTOSIS; HELA CELL; HUMAN; HUMAN CELL; HYDROPHILICITY; HYDROPHOBICITY; IN VIVO STUDY; NANOENCAPSULATION; NUCLEAR MAGNETIC RESONANCE IMAGING; POLYMERIZATION; PRIORITY JOURNAL;

CELL DEATH; DEXTRANS; DOXORUBICIN; DRUG CARRIERS; DRUG DELIVERY SYSTEMS; FLOW CYTOMETRY; FOLIC ACID; HELA CELLS; HUMANS; HYDROPHOBIC AND HYDROPHILIC INTERACTIONS; MAGNETIC RESONANCE IMAGING; MAGNETIC RESONANCE SPECTROSCOPY; MAGNETITE NANOPARTICLES; MICROSCOPY, CONFOCAL; NANOPARTICLES; NEOPLASMS; POLYMERS;

EID: 77957318157     PISSN: 01429612     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2010.08.039     Document Type: Article

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