High endemicity and low molecular diversity of hepatitis B virus infections in pregnant women in a rural district of north cameroon

PLoS ONE

Volumn 8, Issue 11, 2013, Pages

  Ducancelle, Alexandra ^a   Abgueguen, Pierre ^a   Birguel, Jacques ^b   Mansour, Wael ^a   Pivert, Adeline ^a   Guillou Guillemette, Hélène Le ^a   Sobnangou, Jean Jacques ^c   Rameau, Amélie ^a   Huraux, Jean Marie ^d   Lunel Fabiani, Françoise ^a  

^a ANGERS UNIVERSITY HOSPITAL   (France)

^b Catholic Hospital of Tokombéré   (Cameroon)

^c Catholic Hospital of Tokombéré ^*  (Cameroon)

^d ASSISTANCE PUBLIQUE HÔPITAUX DE PARIS   (France)

Author keywords

[No Author keywords available]

Indexed keywords

HEPATITIS B SURFACE ANTIGEN; HEPATITIS B(E) ANTIGEN; VIRUS DNA;

ADULT; AMINO ACID SUBSTITUTION; ARTICLE; CAMEROON; DELTA AGENT HEPATITIS; ENDEMIC DISEASE; FEMALE; GENE MUTATION; GENETIC VARIABILITY; HEPATITIS B; HEPATITIS B RAPID TEST; HEPATITIS B VIRUS; HEPATITIS DELTA VIRUS; HUMAN; MAJOR CLINICAL STUDY; NUCLEOTIDE SEQUENCE; PREGNANT WOMAN; PREVALENCE; RURAL AREA; VIRUS LOAD; VIRUS TRANSMISSION; YOUNG ADULT;

ADOLESCENT; ADULT; CAMEROON; FEMALE; GENETIC VARIATION; GENOTYPE; HEPATITIS B; HEPATITIS B E ANTIGENS; HEPATITIS B SURFACE ANTIGENS; HEPATITIS B VIRUS; HUMANS; MIDDLE AGED; MUTATION; PHENOTYPE; PREGNANCY; PREVALENCE; RURAL POPULATION; SEROTYPING; VIRAL LOAD; YOUNG ADULT;

EID: 84893087283     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0080346     Document Type: Article

References (49)

1. Fattovich G, Bortolotti F, Donato F (2008) Natural history of chronic hepatitis B: special emphasis on disease progression and prognostic factors. J Hepatol48: 335-352. doi:10.1016/S0168-8278(08)60894-6. PubMed: 18096267.
2. Kwon SY, Lee CH (2011) Epidemiology and prevention of hepatitis B virus infection. Korean J Hepatol17: 87-95. doi:10.3350/kjhep.2011.17.2.87. PubMed: 21757978.
3. Liang TJ (2009) Hepatitis B: the virus and disease. Hepatology.49: S13-S21. doi:10.1002/hep.22881. PubMed: 19399811.
4. Lok AS, McMahon BJ (2009) Chronic hepatitis B: update 2009. Hepatology.50: 661-662. doi:10.1002/hep.23190. PubMed: 19714720.
5. WHO (2008) orld Health Organization fact sheet no 204 (2004 Revised August 2008)
6. Modi AA, Feld JJ (2007) Viral hepatitis and HIV in Africa. AIDS Rev9: 25-39. PubMed: 17474311.
7. Franco E, Bagnato B, Marino MG, Meleleo C, Serino L et al. (2012) Hepatitis B: Epidemiology and prevention in developing countries. World. J Hepatol4: 74-80.
8. Ott JJ, Stevens GA, Groeger J, Wiersma ST (2012) Global epidemiology of hepatitis B virus infection: new estimates of age-specific HBsAg seroprevalence and endemicity. Vaccine.30: 2212-2219. doi:10.1016/j.vaccine.2011.12.116. PubMed: 22273662.
9. Hennig BJ, Hall AJ (2012) Host genetic factors in hepatitis B infection, liver cancer and vaccination response: A review with a focus on Africa. Sci Total Environ423: 202-209. doi:10.1016/j.scitotenv.2010.09.036. PubMed: 20970823.
10. Edmunds WJ, Medley GF, Nokes DJ, Hall AJ, Whittle HC (1993) The influence of age on the development of the hepatitis B carrier state. Proc Biol Sci253: 197-201. doi:10.1098/rspb.1993.0102. PubMed: 8397416. (Pubitemid 23262603)
11. Hyams KC (1995) Risks of chronicity following acute hepatitis B virus infection: a review. Clin Infect Dis20: 992-1000. doi:10.1093/clinids/20.4.992. PubMed: 7795104.
12. Lee C, Gong Y, Brok J, Boxall EH, Gluud C (2006) Effect of hepatitis B immunisation in newborn infants of mothers positive for hepatitis B surface antigen: systematic review and meta-analysis. Bmj332: 328-336. doi:10.1136/bmj.38719.435833.7C. PubMed: 16443611.
13. Echevarría JM, Avellón A (2006) Hepatitis B virus genetic diversity. J Med Virol78 Suppl 1: S36-S42. doi:10.1002/jmv.20605. PubMed: 16622876.
14. Kim BK, Revill PA, Ahn SH (2011) HBV genotypes: relevance to natural history, pathogenesis and treatment of chronic hepatitis B. Antivir Ther16: 1169-1186. doi:10.3851/IMP1982. PubMed: 22155900.
15. Kramvis A, Kew M, François G (2005) Hepatitis B virus genotypes. Vaccine.23: 2409-2423. doi:10.1016/j.vaccine.2004.10.045. PubMed: 15752827.
16. Kurbanov F, Tanaka Y, Mizokami M (2010) Geographical and genetic diversity of the human hepatitis B virus. Hepatol Res40: 14-30. doi:10.1111/j.1872-034X.2009.00601.x. PubMed: 20156297.
17. Hsieh TH, Liu CJ, Chen DS, Chen PJ (2006) Natural course and treatment of hepatitis D virus infection. J Formos Med Assoc105: 869-881. doi:10.1016/S0929-6646(09)60172-8. PubMed: 17098688.
18. Hughes SA, Wedemeyer H, Harrison PM (2011) Hepatitis delta virus. Lancet.378: 73-85. doi:10.1016/S0140-6736(10)61931-9. PubMed: 21511329.
19. Le Gal F, Gault E, Ripault MP, Serpaggi J, Trinchet JC et al. (2006) Eighth major clade for hepatitis delta virus. Emerg Infect Dis12: 1447-1450. doi:10.3201/eid1209.060112. PubMed: 17073101. (Pubitemid 44455228)
20. Radjef N, Gordien E, Ivaniushina V, Gault E, Anaïs P et al. (2004) Molecular phylogenetic analyses indicate a wide and ancient radiation of African hepatitis delta virus, suggesting a deltavirus genus of at least seven major clades. J Virol78: 2537-2544. doi:10.1128/JVI.78.5.2537-2544.2004. PubMed: 14963156. (Pubitemid 38228948)
21. Yeh CT, Lai MW (2012) Eliminating hepatitis B virus through neonatal vaccination: can we make it? J Hepatol.57: 484-485.
22. Villeneuve JP, Durantel D, Durantel S, Westland C, Xiong S et al. (2003) Selection of a hepatitis B virus strain resistant to adefovir in a liver transplantation patient. J Hepatol39: 1085-1089. doi:10.1016/j.jhep.2003.09.022. PubMed: 14642631. (Pubitemid 37523785)
23. Friedt M, Gerner P, Lausch E, Trübel H, Zabel B et al. (1999) Mutations in the basic core promotor and the precore region of hepatitis B virus and their selection in children with fulminant and chronic hepatitis B. Hepatology.29: 1252-1258. doi:10.1002/hep.510290418. PubMed: 10094972. (Pubitemid 29168762)
24. Ivaniushina V, Radjef N, Alexeeva M, Gault E, Semenov S et al. (2001) Hepatitis delta virus genotypes I and II cocirculate in an endemic area of Yakutia, Russia. J Gen Virol82: 2709-2718. PubMed: 11602783.
25. Birguel J, Ndong JG, Akhavan S, Moreau G, Sobnangou JJ et al. (2011) [Viral markers of hepatitis B, C and D and HB vaccination status of a health care team in a rural district of Cameroon]. Med Trop (Mars). 71: 201-202.
26. Bottero J, Boyd A, Gozlan J, Lemoine M, Carrat F et al. (2013) Performance of rapid tests for detection of HBsAg and anti-HBsAb in a large cohort, France. J Hepatol58: 473-478. doi:10.1016/S0168-8278(13)61164-2. PubMed: 23183527.
27. Abdou Chekaraou M, Brichler S, Mansour W, Le Gal F, Garba A et al. (2010) A novel hepatitis B virus (HBV) subgenotype D (D8) strain, resulting from recombination between genotypes D and E, is circulating in Niger along with HBV/E strains. J Gen Virol91: 1609-1620. doi:10.1099/vir.0.018127-0. PubMed: 20147517.
28. Mansour W, Malick FZ, Sidiya A, Ishagh E, Chekaraou MA et al. (2012) Prevalence, risk factors, and molecular epidemiology of hepatitis B and hepatitis delta virus in pregnant women and in patients in Mauritania. J Med Virol84: 1186-1198. doi:10.1002/jmv.23336. PubMed: 22711346.
29. Kfutwah AK, Tejiokem MC, Njouom R (2012) A low proportion of HBeAg among HBsAg-positive pregnant women with known HIV status could suggest low perinatal transmission of HBV in Cameroon. Virol J9: 62. doi:10.1186/1743-422X-9-62. PubMed: 22401702.
30. Foupouapouognigni Y, Noah DN, Sartre MT, Njouom R (2011) High prevalence and predominance of hepatitis delta virus genotype 1 infection in Cameroon. J Clin Microbiol49: 1162-1164. doi:10.1128/JCM.01822-10. PubMed: 21209162.
31. Mbanya DN, Takam D, Ndumbe PM (2003) Serological findings amongst first-time blood donors in Yaoundé, Cameroon: is safe donation a reality or a myth? Transfus Med13: 267-273. doi:10.1046/j.1365-3148.2003.00453.x. PubMed: 14617337. (Pubitemid 37462039)
32. Mansour W, Bollahi MA, Hamed CT, Brichler S, Le Gal F et al. (2012) Virological and epidemiological features of hepatitis delta infection among blood donors in Nouakchott, Mauritania. J Clin Virol55: 12-16. doi:10.1016/j.jcv.2012.05.011. PubMed: 22704272.
33. Candotti D, Danso K, Allain JP (2007) Maternofetal transmission of hepatitis B virus genotype E in Ghana, west Africa. J Gen Virol88: 2686-2695. doi:10.1099/vir.0.83102-0. PubMed: 17872520. (Pubitemid 47555021)
34. Makuwa M, Caron M, Souquière S, Malonga-Mouelet G, Mahé A et al. (2008) Prevalence and genetic diversity of hepatitis B and delta viruses in pregnant women in Gabon: molecular evidence that hepatitis delta virus clade 8 originates from and is endemic in central Africa. J Clin Microbiol46: 754-756. doi:10.1128/JCM.02142-07. PubMed: 18077651. (Pubitemid 351231330)
35. Ampofo W, Nii-Trebi N, Ansah J, Abe K, Naito H et al. (2002) Prevalence of blood-borne infectious diseases in blood donors in Ghana. J Clin Microbiol40: 3523-3525. doi:10.1128/JCM.40.9.3523-3525.2002. PubMed: 12202610. (Pubitemid 34977485)
36. Touré-Fall AO, Dièye TN, Sall A, Diop M, Seck M et al. (2009) [Residual risk of transmission of HIV and HBV, in Senegalese national blood bank from 2003 to 2005]. Transfus Clin Biol16: 439-443. doi:10.1016/j.tracli.2009.09.005. PubMed: 19926508.
37. Buseri FI, Muhibi MA, Jeremiah A (2009) Sero-epidemiology of transfusion-transmissible infectious diseases among blood donors in Osogbo, south-west Nigeria. Blood Transfus7: 293-299. PubMed: 20011640.
38. Acquaye JK, Mingle JA (1994) Hepatitis B viral markers in Ghanaian pregnant women. West Afr J Med13: 134-137. PubMed: 7841099.
39. Emechebe GO, Ikefuna AN, Ilechukwu GC, Igwe WC, Ejiofor OS et al. (2009) Hepatitis B virus infection in Nigeria - A review Nigerian Med J. 50: 18-22.
40. Ott JJ, Stevens GA, Wiersma ST. (2012) The risk of perinatal hepatitis B virus transmission: hepatitis B e antigen (HBeAg) prevalence estimates for all world regions. BMC Infect Dis12: 131. doi: 10.1186/1471-2334-12-131. PubMed: 22682147.
41. Kurbanov F, Tanaka Y, Fujiwara K, Sugauchi F, Mbanya D et al. (2005) A new subtype (subgenotype) Ac (A3) of hepatitis B virus and recombination between genotypes A and E in Cameroon. J Gen Virol. 86: 2047-2056. (Pubitemid 40916389)
42. Olinger CM, Venard V, Njayou M, Oyefolu AO, Maïga I et al. (2006) Phylogenetic analysis of the precore/core gene of hepatitis B virus genotypes E and A in West Africa: new subtypes, mixed infections and recombinations. J Gen Virol87: 1163-1173. doi:10.1099/vir.0.81614-0. PubMed: 16603517.
43. Kramvis A, Kew MC (2007) Epidemiology of hepatitis B virus in Africa, its genotypes and clinical associations of genotypes. Hepatol Res37: S9-S19. doi:10.1111/j.1872-034X.2007.00098.x. PubMed: 17627641. (Pubitemid 47086511)
44. Garmiri P, Loua A, Haba N, Candotti D, Allain JP (2009) Deletions and recombinations in the core region of hepatitis B virus genotype E strains from asymptomatic blood donors in Guinea, west Africa. J Gen Virol90: 2442-2451. doi:10.1099/vir.0.012013-0. PubMed: 19535503.
45. Fujiwara K, Tanaka Y, Orito E, Ohno T, Kato T et al. (2005) Distribution of HBV genotypes among HBV carriers in Benin:phylogenetic analysis and virological characteristics of HBV genotype E. World J Gastroenterol11: 6410-6415. PubMed: 16425408.
46. Liu C, Gao H, Zhai S, Liu B. (2011) Molecular characterization, chromosomal localization, expression profile and association analysis with carcass traits of the porcine dickkopf homolog1 gene. Mol Biol Rep38: 1929-1934. doi:10.1007/s11033-010-0313-x. PubMed: 20848216.
47. Poustchi H, Mohamadkhani A, Bowden S, Montazeri G, Ayres A et al. (2008) Clinical significance of precore and core promoter mutations in genotype D hepatitis B-related chronic liver disease. J Viral Hepat15: 753-760. doi:10.1111/j.1365-2893.2008.00998.x. PubMed: 18507754.
48. Bekondi C, Olinger CM, Boua N, Talarmin A, Muller CP et al. (2007) Central African Republic is part of the West-African hepatitis B virus genotype E crescent. J Clin Virol40: 31-37. doi:10.1016/j.jcv.2007.05.009. PubMed: 17689139. (Pubitemid 47307431)
49. Ragheb M, Elkady A, Tanaka Y, Murakami S, Attia FM et al. (2012) Multiple intra-familial transmission patterns of hepatitis B virus genotype D in north-eastern Egypt. J Med Virol84: 587-595. doi:10.1002/jmv.23234. PubMed: 22337297.