Methicillin-resistant Staphylococcus aureus in early ventilator-associated pneumonia: Cause for concern?

Surgical Infections

Volumn 14, Issue 6, 2013, Pages 520-524

  Hill, David M ^a   Schroeppel, Thomas J ^b   Magnotti, Louis J ^b   Clement, L Paige ^a   Sharpe, John P ^b   Fischer, Peter E ^c   Weinberg, Jordan A ^b   Croce, Martin A ^b   Fabian, Timothy C ^b  

^a Regional Medical Center Memphis   (United States)

^b UNIVERSITY OF TENNESSEE HEALTH SCIENCE CENTER   (United States)

^c CAROLINAS MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CEFEPIME; CIPROFLOXACIN; MOXIFLOXACIN; SULTAMICILLIN; VANCOMYCIN;

ADULT; ANTIBIOTIC THERAPY; ARTICLE; BLOOD TRANSFUSION; DATA BASE; DISEASE SEVERITY; ENTEROBACTER; ESCHERICHIA COLI; FEMALE; HAEMOPHILUS; HEALTH CARE COST; HUMAN; INJURY SEVERITY; KLEBSIELLA; MAJOR CLINICAL STUDY; MALE; METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS; METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS INFECTION; METHICILLIN SUSCEPTIBLE STAPHYLOCOCCUS AUREUS; MORTALITY; OUTCOME ASSESSMENT; PREDICTIVE VALUE; PRIORITY JOURNAL; PSEUDOMONAS AERUGINOSA; STREPTOCOCCUS PNEUMONIAE; VENTILATOR ASSOCIATED PNEUMONIA;

ADULT; ANTI-BACTERIAL AGENTS; FEMALE; HUMANS; INCIDENCE; MALE; METHICILLIN-RESISTANT STAPHYLOCOCCUS AUREUS; PNEUMONIA, STAPHYLOCOCCAL; PNEUMONIA, VENTILATOR-ASSOCIATED; SURVIVAL ANALYSIS; TREATMENT OUTCOME;

EID: 84893020723     PISSN: 10962964     EISSN: 15578674     Source Type: Journal    
DOI: 10.1089/sur.2012.166     Document Type: Article

References (35)

1. Chastre J, Fagon JY. Ventilator-Associated pneumonia. Am J Respir Crit Care Med 2002;165:867-903
2. Rello J, Ollendorf DA, Oster G, et al. Epidemiology and outcomes of ventilator-Associated pneumonia in a large US database. Chest 2002;122:2115-2121
3. Cook D, De Jonghe B, Brochard L, Brun-Buisson C. Influence of airway management on ventilator-Associated pneumonia: Evidence from randomized trials. JAMA 1998;279:781-787
4. Croce MA, Tolley EA, Fabian TC. A formula for prediction of posttraumatic pneumonia based on early anatomic and physiologic parameters. J Trauma 2003;54:724-730
5. Magnotti LJ, Croce MA, Fabian TC. Is ventilator-Associated pneumonia in trauma patients an epiphenomenon or a cause of death? Surg Infect 2004;5:237-242
6. Guidelines for the management of adults with hospitalacquired, ventilator-Associated, and healthcare-Associated pneumonia. Am J Respir Crit Care Med 2005;171:388-416
7. Wood GC, Mueller EW, Croce MA, et al. Evaluation of a clinical pathway for ventilator-Associated pneumonia: Changes in bacterial flora and the adequacy of empiric antibiotics over a three-year period. Surg Infect 2005;6:203-213
8. Dupont H, Mentec H, Sollet JP, Bleichner G. Impact of appropriateness of initial antibiotic therapy on the outcome of ventilator-Associated pneumonia. Intensive Care Med 2001; 27:355-362
9. Magnotti LJ, Schroeppel TJ, Fabian TC, et al. Reduction in inadequate empiric antibiotic therapy for ventilatorassociated pneumonia: Impact of a unit-specific treatment pathway. Am Surg 2008;74:516-523
10. Kolleff MH. Appropriate antibiotic therapy for ventilatorassociated pneumonia and sepsis: A necessity, not an issue for debate. Intensive Care Med 2003;29:147-149
11. Croce MA, Fabian TC, Waddle-Smith L, Maxwell RA. Identification of early predictors for post-Traumatic pneumonia. Am Surg 2001;67:105-110
12. Langer M, Cigada M, Mandelli M, et al. Early onset pneumonia: A multicenter study in intensive care units. Intensive Care Med 1987;13:342-346
13. Vardakas KZ, Matthaiou DK, Falagas ME. Incidence, characteristics and outcomes of patients with severe community acquired-MRSA pneumonia. Eur Respir J 2009;34:1148-1158
14. Kollef MH, Shorr A, Tabak YP, et al. Epidemiology and outcomes of health-care-Associated pneumonia: Results from a large US database of culture-positive pneumonia. Chest 2005;128:3854-3862
15. Ott E, Bange FC, Reichardt C, et al. Costs of nosocomial pneumonia caused by methicillin-resistant Staphylococcus aureus. J Hosp Infect 2010;76:300-303
16. Wunderink RG. Clinical criteria in the diagnosis of ventilatorassociated pneumonia. Chest 2000;117:191S-194S.
17. Croce MA, Fabian TC, Schurr MJ, et al. Using bronchoalveolar lavage to distinguish nosocomial pneumonia from systemic inflammatory response syndrome: A prospective analysis. J Trauma 1995;39:1134-1140
18. Croce MA, Fabian TC, Waddle-Smith L, et al. Utility of Gram's stain and efficacy of quantitative cultures for posttraumatic pneumonia: A prospective study. Ann Surg 1998; 227:743-755
19. Swanson JM, Mueller EW, Croce MA, et al. Changes in pulmonary cytokines during antibiotic therapy for ventilatorassociated pneumonia. Surg Infect 2010;11:161-167
20. Mueller EW, Hanes SD, Croce MA, et al. Effect from multiple episodes of inadequate empiric antibiotic therapy for ventilator-Associated pneumonia on morbidity and mortality among critically ill trauma patients. J Trauma 2005;58: 94-101
21. Croce MA, Fabian TC, Stewart RM, et al. Empiric monotherapy versus combination therapy of nosocomial pneumonia in trauma patients. J Trauma 1993;35:303-311
22. Croce MA, Fabian TC. Monotherapy of gram-negative nosocomial pneumonia. J Tenn Med Assoc 1993;86:353-354
23. Swanson JM, Wood GC, Croce MA, et al. Utility of preliminary bronchoalveolar lavage results in suspected ventilatorassociated pneumonia. J Trauma 2008;65:1271-1277
24. Mueller EW, Wood GC, Kelley MS, et al. The predictive value of preliminary bacterial colony counts from bronchoalveolar lavage in critically ill trauma patients. Am Surg 2003;69:749-756
25. Mueller EW, Croce MA, Boucher BA, et al. Repeat bronchoalveolar lavage to guide antibiotic duration for ventilatorassociated pneumonia. J Trauma 2007;63:1329-1337
26. Croce MA, Fabian TC, Shaw B, et al. Analysis of charges associated with diagnosis of nosocomial pneumonia: Can routine bronchoscopy be justified? J Trauma 1994;37:721-727
27. Miller PR, Meredith JW, Chang MC. Optimal threshold for diagnosis of ventilator-Associated pneumonia using bronchoalveolar lavage. J Trauma 2003;55:263-268
28. Croce MA, Fabian TC, Mueller EW, et al. The appropriate diagnostic threshold for ventilator-Associated pneumonia using quantitative cultures. J Trauma 2004;56:931-936
29. Cook A, Norwood S, Berne J. Ventilator-Associated pneumonia is more common and of less consequence in trauma patients compared with other critically ill patients. J Trauma 2010;69:1083-1091
30. Mera RM, Suaya JA, Amrine-Madsen H, et al. Increasing role of Staphylococcus aureus and community-Acquired methicillin-resistant Staphylococcus aureus infections in the United States: A 10-year trend of replacement and expansion. Microb Drug Resist 2011;17:321-328
31. Rello J, Torres A, Ricart M, et al. Ventilator-Associated pneumonia by Staphylococcus aureus. Comparison of methicillin-resistant and methicillin-sensitive episodes. Am J Respir Crit Care Med 1994;150:1545-1549
32. Eckert MJ, Davis KA, Reed RL, 2nd, et al. Ventilator-Associated pneumonia, like real estate: Location really matters. J Trauma 2006;60:104-110
33. Bekaert M, Timsit JF, Vansteelandt S, et al. Attributable mortality of ventilator-Associated pneumonia: A reappraisal using causal analysis. Am J Respir Crit Care Med 2011;184: 1133-1139
34. Sharpe JP, Weinberg JA, Magnotti LJ, et al. Toward a better definition of massive transfusion: Focus on the interval of hemorrhage control. J Trauma Acute Care Surg. 2012;74: 1553-1557
35. Spinella PC, Perkins JG, Grathwohl KW, et al. Effect of plasma and red blood cell transfusions on survival in patients with combat related traumatic injuries. J Trauma 2008; 64(2 Suppl):S69-S77