Mechanisms of Mycobacterium avium subsp. paratuberculosis induced apoptosis and necrosis in bovine macrophages

Veterinary Microbiology

Volumn 165, Issue 3-4, 2013, Pages 392-401

  Periasamy, Sivakumar ^a   Tripathi, Bhupendra N ^a   Singh, Nem ^a  

^a INDIAN VETERINARY RESEARCH INSTITUTE   (India)

Author keywords

Apoptosis; Bovine; Macrophages; Mycobacteria; Mycobacterium avium subsp. paratuberculosis (Map); Necrosis

Indexed keywords

CASPASE; NITRIC OXIDE;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL STRUCTURE; CONTROLLED STUDY; DISORDERS OF MITOCHONDRIAL FUNCTIONS; ELECTRON MICROSCOPY; FLUORESCENCE MICROSCOPY; MACROPHAGE; MYCOBACTERIUM PARATUBERCULOSIS; NONHUMAN; PARATUBERCULOSIS;

BOVINAE; CORYNEBACTERINEAE; MYCOBACTERIUM AVIUM SUBSP. PARATUBERCULOSIS;

ANIMALS; APOPTOSIS; CATTLE; CATTLE DISEASES; HOST-PATHOGEN INTERACTIONS; MACROPHAGES; MICROSCOPY, ELECTRON, TRANSMISSION; MITOCHONDRIA; MYCOBACTERIUM AVIUM SUBSP. PARATUBERCULOSIS; NECROSIS; NITRIC OXIDE; PARATUBERCULOSIS;

EID: 84893016561     PISSN: 03781135     EISSN: 18732542     Source Type: Journal    
DOI: 10.1016/j.vetmic.2013.03.030     Document Type: Article

References (30)

1. Abebe M., Kim L., Rook G., Aseffa A., Wassie L., Zewdie M., Zumla A., Engers H., Andersen P., Doherty T.M. Modulation of cell death by M. tuberculosis as a strategy for pathogen survival. Clin. Dev. Immunol. 2011, 2011. 11 pp., article ID: 678570.
2. Allen S., Sotos J., Sylte M.J., Czuprynski C.J. Use of Hoechst 33342 staining to detect apoptotic changes in bovine mononuclear phagocytes infected with Mycobacterium avium subsp. paratuberculosis. Clin. Diagn. Lab. Immunol. 2001, 8:460-464.
3. Bannantine J.P., Stabel J.R. Killing of Mycobacterium avium subsp. paratuberculosis within macrophages. BMC Microbiol. 2002, 2:2-9.
4. Berger S.T., Griffin F.T. A comparison of ovine monocyte-derived macrophage function following infection with Mycobacterium avium ssp. avium and Mycobacterium avium ssp. paratuberculosis. Immunol. Cell Biol. 2006, 84:349-356.
5. Castedo M., Ferri K., Roumier T., Metivier D., Zamzami N., Kroemer G. Quantitation of mitochondrial alterations associated with apoptosis. J. Immunol. Methods 2002, 265:39-47.
6. Chen M., Gan H., Remold H.G. A mechanism of virulence: virulent Mycobacterium tuberculosis strain H37Rv, but not attenuated H37Ra, causes significant mitochondrial inner membrane disruption in macrophages leading to necrosis. J. Immunol. 2006, 176:3707-3716.
7. Chipuk J.E., Bouchier-Hayes L., Green D.R. Mitochondrial outer membrane permeabilization during apoptosis: the innocent bystander scenario. Cell Death Differ. 2006, 13:1396-1402.
8. Green D.R., Kroemer G. The pathophysiology of mitochondrial cell death. Science 2004, 305:626-629.
9. Guicciardi M.E., Leist M., Gores G.J. Lysosomes in cell death. Oncogene 2004, 23:2881-2890.
10. Hostetter J., Steadham E., Haynes J., Bailey T.B., Cheville N.F. Cytokine effects on maturation of the phagosome containing Mycobacterium avium subspecies paratuberculosis in J774 cells. FEMS Immunol. Med. Microbiol. 2002, 34:127-134.
11. Jennings R.B., Ganote C.E. Mitochondrial structure and function in acute myocardial ischemic injury. Circ. Res. 1976, 38:80-91.
12. Kabara E., Coussens P.M. Infection of primary bovine macrophages with Mycobacterium avium subspecies paratuberculosis suppresses host cell apoptosis. Front. Microbiol. 2012, 3:215. epub 2012 Jul 20.
13. Kelly D.M., ten Bokum A.M.C., O'Leary S.M., O'Sullivan M.P., Keane J. Bystander macrophage apoptosis after Mycobacterium tuberculosis H37Ra infection. Infect. Immun. 2008, 76:351-360.
14. Kim J.S., He L., Lemasters J.J. Mitochondrial permeability transition: a common pathway to necrosis and apoptosis. Biochem. Biophys. Res. Commun. 2003, 304:463-470.
15. Klingler K., Tchou-wong K., Brandli O., Aston C., Kim R., Chi C., Rom W.N. Effects of mycobacteria on regulation of apoptosis in mononuclear phagocytes. Infect. Immun. 1997, 65:5272-5278.
16. Kroemer G., Dallaporta B., Resche-Rigon M. The mitochondrial death/life regulator in apoptosis and necrosis. Annu. Rev. Physiol. 1998, 60:619-642.
17. Lee J., Remold H.G., Ieong M.H., Kornfeld H. Macrophage apoptosis in response to high intracellular burden of Mycobacterium tuberculosis is mediated by a novel caspase-ipdependent pathway. J. Immunol. 2006, 176:4267-4274.
18. -δδCT method. Methods 2001, 25:402-408.
19. Ly J.D., Grubb D.R., Lawen A. The mitochondrial membrane potential (deltapsi(m)) in apoptosis- an update. Apoptosis 2003, 8:115-128.
20. Molloy A., Laochumroonvorapong P., Kaplan G. Apoptosis, but not necrosis, of infected monocytes is coupled with killing of intracellular bacillus Calmette-Guerin. J. Exp. Med. 1994, 180:1499-1509.
21. O'Sullivan M.P., O'Leary S., Kelly D.M., Keane J. A caspase-independent pathway mediates macrophage cell death in response to Mycobacterium tuberculosis infection. Infect. Immun. 2007, 75:1984-1993.
22. Periasamy S., Singh N. Mycobacterium avium subsp. paratuberculosis induced apoptosis: a complex mechanism in bovine macrophage. 9th Proceedings of International Colloquium on Paratuberculosis held at Japan during October 2007 2007, 43.
23. Ponnusamy D., Periasamy S., Tripathi B.N., Pal A. Mycobacterium avium subsp. paratuberculosis invades through M cells and enterocytes across ileal and jejunal mucosa of lambs. Res. Vet. Sci. 2013, 94:306-312.
24. Rojas M., Barrera L.F., Garcia L.F. Induction of apoptosis in murine macropahges by Mycobacterium tuberculosis is reactive oxygen intermediates independent. Biochem. Biophys. Res. Commun. 1998, 247:436-442.
25. Sivakumar P., Tripathi B.N., Singh N. Detection of Mycobacterium avium subsp. paratuberculosis in intestinal and lymph node tissues of water buffalo by bacterial culture and PCR. Vet. Microbiol. 2005, 108:263-270.
26. van Loo G., van Gurp M., Depuydt B., Srinivasula S.M., Rodriguez I., Alnemri E.S., Gevaert K., Vandekerckhove J., Declercq W., Vandenabeele P. The serine protease Omi/HtrA2 is released from mitochondria during apoptosis, Omi interacts with caspase-inhibitor XIAP and induces enhanced caspase activity. Cell Death Differ. 2002, 9:20-26.
27. Whelan R.S., Konstantinidisa K., Weid A., Chene Y., Reynac D.E., Jhaa S., Yang Y., Calvertg J.W., Lindstenh T., Thompsonh C.B., Crowi M.T., Gavathiotis E., Dorn C.E., O'Rourked B., Kitsisa R.N. Bax regulates primary necrosis through mitochondrial dynamics. Proc. Natl. Acad. Sci. U.S.A. 2012, 109:6566-6571.
28. Woo S., Heintz J.A., Albrecht R., Barletta R.G., Czuprynski C.J. Life and death in bovine monocytes: the fate of Mycobacterium avium subsp. paratuberculosis. Microb. Pathog. 2007, 43:106-113.
29. Zeiss C.J. The apoptosis-necrosis continuum: insights from genetically altered mice. Vet. Pathol. 2003, 40:481-495.
30. Zurbrick B., Czuprynski C. Ingestion and intracellular growth of Mycobacterium paratuberculosis within bovine blood monocytes and monocyte-derived macrophages. Infect. Immun. 1998, 55:1588-1593.