Pharmacology on microfluidics: Multimodal analysis for studying cell-cell interaction

Current Opinion in Pharmacology

Volumn 13, Issue 5, 2013, Pages 821-828

  Delamarche, Emmanuel ^a   Tonna, Noemi ^b,c   Lovchik, Robert D ^a   Bianco, Fabio ^b   Matteoli, Michela ^d,e  

^a IBM RESEARCH ZURICH   (Switzerland)

^b Neuro Zone srl   (Italy)

^c CNR   (Italy)

^d UNIVERSITY OF MILAN   (Italy)

^e HUMANITAS CLINICAL AND RESEARCH CENTER   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

DIMETICONE;

ARTICLE; CANCER RESEARCH; CELL ADHESION; CELL COMMUNICATION; CELL CULTURE; CELL INTERACTION; CELL SUSPENSION; CHRONIC INFLAMMATION; COCULTURE; ENDOTHELIUM CELL; HUMAN; MICROFLUIDICS; MICROVASCULATURE; NERVOUS SYSTEM INFLAMMATION; NONHUMAN; PRIORITY JOURNAL; SHEAR STRESS; SIGNAL TRANSDUCTION; TUMOR CELL;

CELL COMMUNICATION; MICROFLUIDICS; PHARMACOLOGY;

EID: 84892991359     PISSN: 14714892     EISSN: 14714973     Source Type: Journal    
DOI: 10.1016/j.coph.2013.07.005     Document Type: Review

References (44)

1. Neuži P, Giselbrecht S, Länge K, Huang TJ, Manz A: Revisiting lab-On-A-Chip technology for drug discovery. Nat Rev Drug Discov 2012, 11: 620-632.
2. Whitesides GM: The origins and the future of microfluidics. Nature 2006, 442: 368-373. (Pubitemid 44264779)
3. Ciftlik AT, Lehr HA, Gijs MA: Microfluidic processor allows rapid HER2 immunohistochemistry of breast carcinomas and significantly reduces ambiguous (2+) read-outs. Proc Natl Acad Sci U S A 2013, 110: 5363-5368.
4. Tang SKY, Whitesides GM: Basic microfluidic and soft lithographic techniques. In Optofluidics: Fundamentals, Devices and Applications. Edited by Fainman Y, Lee LP, Psaltis D, Yang C. McGraw-Hill; 2010: 7-28.
5. Folch A: Introduction to BioMEMS. CRC Press; 2013.
6. Tourovskaia A, Figueroa-Masot X, Folch A: Long-term microfluidic cultures of myotube microarrays for high-throughput focal stimulation. Nat Protocols 2006, 1: 1092-1104.
7. Futai N, Gu W, Song JW, Takatama S: Handheld recirculation system and customized media for microfluidic cell culture. Lab Chip 2006, 6: 149-154.
8. Di Carlo D, Wu LY, Lee LP: Dynamic single cell culture arrays. Lab Chip 2006, 6: 1445-1449. (Pubitemid 44656865)
9. Eyer K, Stratz S, Kuhn P, Küster SK, Dittrich PS: Implementing enzyme-linked immunoadsorbent assays on a microfluidic chip to quantify intracellular molecules in single cells. Anal Chem 2013 http://dx.doi.org/10. 1021/ac303628j.
10. Hong S, Pan Q, Lee LP: Single-cell level co-culture platform for intercellular communication. Integr Biol 2012, 4: 374-380.
11. Lovchik RD, Bianco F, Matteoli M, Delamarche E: Controlled deposition of cells in sealed microfluidics using flow velocity boundaries. Lab Chip 2009, 9: 1395-1402.
12. Lovchik RD, Bianco F, Tonna N, Ruiz A, Matteoli M, Delamarche E: Overflow microfluidic networks for open and closed cultures on chip. Anal Chem 2010, 82: 3936-3942.
13. Lovchik RD, Tonna N, Bianco F, Matteoli M, Delamarche E: A microfluidic device for depositing and addressing two cell populations with intercellular population communication capability. Biomed Microdevices 2010, 12: 275-282.
14. Bianco F, Tonna N, Lovchik RD, Mastrangelo R, Morini R, Ruiz A, Delamarche E, Matteoli M: Overflow microfluidic networks: application to the biochemical analysis of brain cell interactions in complex neuroinflammatory scenarios. Anal Chem 2012, 84: 9833-9840.
15. Fair RB: Digital microfluidics: is a true lab-On-A-Chip possible? Microfluid Nanofluid 2007, 3: 245-281. (Pubitemid 46681552)
16. Srigunapalan S, Eydelnant IA, Simmons CA, Wheeler A: A digital microfluidic platform for primary cell culture and analysis. Lab Chip 2012, 12: 369-375.
17. Shih SCC, Barbulovic-Nad I, Yang X, Fobel R, Wheeler AR: Digital microfluidics with impedance sensing for integrated cell culture and analysis. Biosens Bioelectron 2013, 42: 314-320.
18. Eker B, Meissner R, Bertsch A, Mehta K, Renaud P: Label-free recognition of drug resistance via impedimetric screening of breast cancer cells. PLoS ONE 2013, 8:e57423.
19. Bagnaninchi PO, Drummond N: Real-time label-free monitoring of adipose-derived stem cell differentiation with electric cell- substrate impedance sensing. Proc Natl Acad Sci U S A 2011, 108: 6462-6467.
20. Janhke HG, Braesigk A, Mack TGA, Pönick S, Striggow F, Robitzki AA: Impedance spectroscopy based measurement system for quantitative and label-free real-time monitoring of tauopathy in hippocampal slice cultures. Biosens Bioelectron 2012, 32: 250-258.
21. Taylor AM, Rhee SW, Tu CH, Cribbs DH, Cotman CW, Jeon NL: Microfluidic multicompartment device for neuroscience research. Langmuir 2003, 19: 1551-1556.
22. Taylor AM, Dieterich DC, Ito HT, Kim SA, Schuman EM: Microfluidic local perfusion chambers for the visualization and manipulation of synapses. Neuron 2010, 66: 57-68.
23. Peyrin JM, Deleglise B, Saias L, Vignes M, Gougis P, Magnifico S, Betuing S, Pietri M, Caboche J, Vanhoutte P, Viovy JL, Brugg B: Axon diodes for reconstruction of oriented neuronal networks in microfluidic chambers. Lab Chip 2011, 11: 3663-3673.
24. Wei H, Li H, Mao S, Lin JM: Cell signaling analysis by mass spectrometry under coculture conditions on an integrated microfluidic device. Anal Chem 2011, 83: 9306-9313.
25. Wu HI, Cheng GH, Wong YY, Lin CM, Fang W, Chow WY, Chang YC: A lab-On-A-Chip platform for studying the subcellular functional proteome of neuronal axons. Lab Chip 2010, 10: 647-653.
26. van der Meer AD, Poot AA, Duits MH, Feijen J, Vermes I: Microfluidic technology in vascular research. J Biomed Biotechnol 2009, 2009:823148.
27. Wong KH, Chan JM, Kamm RD, Tien J: Microfluidic models of vascular functions. Annu Rev Biomed Eng 2012, 14: 205-230.
28. Song JW, Munn LL: Fluid forces control endothelial sprouting. Proc Natl Acad Sci U S A 2011, 108: 15342-15347.
29. Rosano JM, Tousi N, Scott RC, Krynska B, Rizzo V, Prabhakarpandian B, Pant K, Sundaram S, Kiani MF: A physiologically realistic in vitro model of microvascular networks. Biomed Microdevices 2009, 11: 1051-1057.
30. Jain RK, Au P, Tam J, Duda DG, Fukumura D: Engineering vascularized tissue. Nat Biotechnol 2005, 23: 821-823. (Pubitemid 43093121)
31. Günther A, Yasotharan S, Vagaon A, Lochovsky C, Pinto S, Yang J, Lau C, Voigtlaender-Bolz J, Bolz SS: A microfluidic platform for probing small artery structure and function. Lab Chip 2010, 10: 2341-2349.
32. Zhang Z, Nagrath S: Microfluidics and cancer: are we there yet? Biomed Microdevices 2013, 29 PMID: 23358873.
33. Buchanan C, Rylander MN: Microfluidic culture models to study the hydrodynamics of tumor progression and therapeutic response. Biotechnol Bioeng 2013 http://dx.doi.org/10.1002/bit.24944.
34. Ma H, Xu H, Qin J: Biomimetic tumor microenvironment on a microfluidic platform. Biomicrofluidics 2013, 7 doi:011501.
35. Khan ZS, Vanapalli SA: Probing the mechanical properties of brain cancer cells using a microfluidic cell squeezer device. Biomicrofluidics 2013, 7 doi:011806.
36. Salmanzadeh A, Sano MB, Gallo-Villanueva RC, Roberts PC, Schmelz EM, Davalos RV: Investigating dielectric properties of different stages of syngeneic murine ovarian cancer cells. Biomicrofluidics 2013, 7 doi:011809.
37. Sun J, Liu C, Li M, Wang J, Xianyu Y, Hu G, Jiang X: Size-based hydrodynamic rare tumor cell separation in curved microfluidic channels. Biomicrofluidics 2013, 7 doi:011802.
38. Chung S, Sudo R, Zervantonakis IK, Rimchala T, Kamm RD: Surface-treatment-induced three-dimensional capillary morphogenesis in a microfluidic platform. Adv Mater 2009, 8, 21: 4863-4867.
39. Zervantonakis IK, Hughes-Alford SK, Charest JL, Condeelis JS, Gertler FB, Kamm RD: Three-dimensional microfluidic model for tumor cell intravasation and endothelial barrier function. Proc Natl Acad Sci U S A 2012, 109: 13515-13520.
40. Huang CP, Lu J, Seon H, Lee AP, Flanagan LA, Kim HY, Putnam AJ, Jeon NL: Engineering microscale cellular niches for three-dimensional multicellular co-cultures. Lab Chip 2009, 9: 1740-1748.
41. Elliott NT, Yuan F: A microfluidic system for investigation of extravascular transport and cellular uptake of drugs in tumors. Biotechnol Bioeng 2012, 109: 1326-1335.
42. Montanez-Sauri SI, Sung KE, Puccinelli JP, Pehlke C, Beebe DJ: Automation of three-dimensional cell culture in arrayed microfluidic devices. J Lab Autom 2011, 16: 171-185.
43. Huang SB, Wang SS, Hsieh CH, Lin YC, Lai CS, Wu MH: An integrated microfluidic cell culture system for high-throughput perfusion three-dimensional cell culture-based assays: effect of cell culture model on the results of chemosensitivity assays. Lab Chip 2013, 13: 1133-1143.
44. Glass CK, Saijo K, Winner B, Marchetto MC, Gage FH: Mechanisms underlying inflammation in neurodegeneration. Cell 2010, 140: 918-934.