Identification of Navβ1 residues involved in the modulation of the sodium channel Nav1.4

PLoS ONE

Volumn 8, Issue 12, 2013, Pages

  Islas, Angel A ^a   Sánchez Solano, Alfredo ^a   Scior, Thomas ^a   Millan PerezPeña, Lourdes ^a   Salinas Stefanon, Eduardo M ^a  

^a BENEMÉRITA UNIVERSIDAD AUTÓNOMA DE PUEBLA   (Mexico)

Author keywords

[No Author keywords available]

Indexed keywords

ISOPROTEIN; SODIUM CHANNEL NAV1.4; VOLTAGE GATED SODIUM CHANNEL BETA 1 SUBUNIT;

ARTICLE; COMPUTER MODEL; CONTROLLED STUDY; DEPOLARIZATION; ELECTROPHYSIOLOGY; NONHUMAN; PHYSICAL CHEMISTRY; PROTEIN FUNCTION; SEQUENCE ANALYSIS; SITE DIRECTED MUTAGENESIS; STRUCTURE ACTIVITY RELATION;

ACTION POTENTIALS; ANIMALS; FEMALE; ION CHANNEL GATING; MODELS, MOLECULAR; MUTAGENESIS, SITE-DIRECTED; OOCYTES; PATCH-CLAMP TECHNIQUES; PROTEIN CONFORMATION; PROTEIN SUBUNITS; SODIUM CHANNELS; XENOPUS LAEVIS;

EID: 84892984231     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0081995     Document Type: Article

References (39)

1. Catterall WA (2000) From ionic currents to molecular mechanism: the structure and function of voltage-gated sodium channels. Neuron 26: 13-25.
2. Brackenbury WJ, Isom LL (2008) Voltage-gated Na+ channels: Potential for β subunits as therapeutic targets. Expert Opin Ther Targets 12: 1191-1203.
3. Catterall WA, Goldin AL, Waxman SG (2005) International Union of Pharmacology XLVII Nomenclature and structure-function relationships of voltage-gated sodium channels. Pharmacol. Rev 57: 397-409. (Pubitemid 43036431)
4. Hille B (2001) Ion channels of excitable membranes. Sunderland, MA: Sinauer Associates Inc Press. 251 p.
5. Brackenbury WJ, Isom LL (2011) Na Channel β Subunits: Overachievers of the Ion Channel Family. Front Pharmacol 28: 2-53.
6. Patton DE, Isom LL, Catterall WA, Goldin AL (1994) The Adult Rat Brain Subunit Modifies Activation and Inactivation Gating of Multiple Sodium Channels. J Biol Chem 269: 17649-17655. (Pubitemid 24218050)
7. Chen C, Cannon SC (1995) Modulation of Na+ channel inactivation by the b1 subunit: a deletion analysis. Pflügers Arch-Eur Physiol 43l: 186-195. (Pubitemid 26017987)
8. Makita N, Bennett PB, George AL Jr (1996) Molecular determinants of beta 1 subunit-induced gating modulation in voltage-dependent Na+ channels. J Neurosci 16(22): 7117-7127. (Pubitemid 26382889)
9. Qu Y, Rogers JC, Chen SF, McCormick KA, Scheuer T, et al. (1999) Functional roles of the extracellular segments of the sodium channel alpha subunit in voltage-dependent gating and modulation by beta1 subunits. J Biol Chem 274(46): 32647-32654. (Pubitemid 129535291)
10. McCormick KA, Srinivasan J, White K, Scheuer T, Catterall WA (1999) The Extracellular Domain of the β1 Subunit Is Both Necessary and Sufficient for β1-like Modulation of Sodium Channel Gating. J Biol Chem 274: 32638-32646. (Pubitemid 129535290)
11. Meadows LS, Malhotra J, Loukas A, Thyagarajan V, Kazen-Gillespie KA, et al. (2002) Functional and Biochemical Analysis of a Sodium Channel beta 1 Subunit Mutation Responsible for Generalized Epilepsy with Febrile Seizures Plus Type 1. J Neurosci 22: 10699-10709. (Pubitemid 36005144)
12. Patino GA, Isom LL (2010) Electrophysiology and beyond: multiple roles of Na+ channel β subunits in development and disease. Neurosci Lett 486(2): 53-59.
13. Zimmer T, Benndorf K (2002) The human heart and rat brain IIA Na+ channels interact with different molecular regions of the β1 subunit. J Gen Physiol 120: 887-895. (Pubitemid 35435019)
14. Nguyen HM, Miyazaki H, Hoshi N, Smith BJ, Nukina N, et al (2012) Modulation of voltage-gated K+ channels by the sodium channel β1 subunit. Proc Natl Acad Sci U S A 109(45): 18577-18582.
15. Valencia A, Pazos F (2006) Prediction of protein-protein interactions from evolutionary information. Methods Biochem Anal 44: 411-426.
16. Ofran Y, Rost B (2007) Protein-protein interaction hotspots carved into sequences. PLoS Comput Biol 3(7): e119.
17. Orta-Salazar G (2004) Mecanismo de acción de la primaquina sobre el canal de Na+ Nav1.5 y Nav1.4 expresado en ovocitos de la rana Xenopus laevis. PhD Thesis.
18. Moran O, Nizzari M, Conti F (2000) Endogenous expression of the beta1A sodium channel subunit in HEK-293 cells. FEBS Lett 473(2): 132-134. (Pubitemid 30254275)
19. Zhang Y (2008) I-TASSER server for protein 3D structure prediction. BMC Bioinformatics 9: 40-48.
20. Combet C, Jambon M, Deleage G, Geourjon C (2002) Geno3D: automatic comparative molecular modelling of protein. Bioinformatics 18: 213-214. (Pubitemid 34145058)
21. Nielsen M, Lundegaard C, Lund O, Petersen TN (2010) CPHmodels-3.0 Remote homology modeling using structure-guided sequence profiles. Nucleic Acids Res l, 38 (Web Server issue): W576-81.
22. Pedretti A, Villa L, Vistoli G (2004) VEGA-an open platform to develop chemo-bio- informatics applications, using plug-in architecture and script programming. J Comput Aided Mol Des 18: 167-173. (Pubitemid 39069412)
23. Meng EC, Pettersen EF, Couch GS, Huang CC, Ferrin TE (2006) Tools for integrated sequence-structure analysis with UCSF Chimera. BMC Bioinformatics 7: 339-349.
24. Willard L, Ranjan A, Zhang H, Monzavi H, Boyko RF, et al. (2003) VADAR: a web server for quantitative evaluation of protein structure quality. Nucleic Acids Res 31: 3316-3319. (Pubitemid 37442148)
25. Snider C, Jayasinghe S, Hristova K, White SH (2009) MPEx: A tool for exploring membrane proteins. Protein Sci 18: 2624-2628.
26. Cole C, Barber JD, Barton GJ (2008) The Jpred 3 secondary structure prediction server. Nucleic Acid Res: 36(Web Server issue): W197-201.
27. Edgar RC (2004) MUSCLE: multiple sequence alignment with high accuracy and high throughput Nucleic Acids Res 32(5): 1792-1797.
28. Smith TF, Waterman MS (1981) Identification of common molecular subsequences. J Mol Biol 147(1): 195-197.
29. Yereddi NR, Cusdin FS, Namadurai S, Packman LC, Monie TP, et al. (2013) The immunoglobulin domain of the sodium channel β3 subunit contains a surface-localized disulfide bond that is required for homophilic binding. FASEB J 27(2): 568-580.
30. Scior T, Wahab HA (2007) Structure prediction of proteins with very low homology. In: Drug Design Research Perspectives. New York, NY: Nova Science Publishers. 675-708 pp.
31. O'Reilly AO, Charalambous K, Nurani G, Powl AM, Wallace BA (2008) G219S mutagenesis as a means of stabilizing conformational f lexibility in the bacterial sodium channel NaChBac. Mol Membr Biol 25(8): 670-676.
32. Xu D, Tsai CJ, Nussinov R (1997) Hydrogen bonds and salt bridges across protein-protein interfaces. Protein Eng 10(9): 999-1012. (Pubitemid 28004646)
33. Isom LL, De Jongh KS, Patton DE, Reber BF, Offord J, et al. (1992) Primary structure and functional expression of the beta 1 subunit of the rat brain sodium channel. Science 256(5058): 839-842.
34. Bennett PB Jr, Makita N, George AL Jr (1993) A molecular basis for gating mode transitions in human skeletal muscle Na+ channels. FEBS Lett 326(1-3): 21-24. (Pubitemid 23200238)
35. Yu EJ, Ko SH, Lenkowski PW, Pance A, Patel MK, et al.(2005) Distinct domains of the sodium channel beta3-subunit modulate channel-gating kinetics and subcellular location. Biochem J 392(Pt 3): 519-526. (Pubitemid 43022731)
36. Xu R, Thomas EA, Gazina EV, Richards KL, Quick M, et al. (2007) Generalized epilepsy with febrile seizures plus-associated sodium channel beta subunit mutations severely reduce beta subunit-mediated modulation of sodium channel function. Neuroscience 148(1): 164-174. (Pubitemid 47211626)
37. Watanabe H, Koopmann TT, Le Scouarnec S, Yang T, Ingram CR, et al (2008) Sodium channel β1 subunit mutations associated with Brugada syndrome and cardiac conduction disease in humans. J Clin Invest 118(6): 2260-2268. (Pubitemid 351872343)
38. Barbieri R, Baroni D, Moran O (2012) Identification of an intra-molecular disulfide bond in the sodium channel β1-subunit. Biochem Biophys Res Commun 420(2): 364-367.
39. Changeux JP (2012) Allostery and the Monod-Wyman-Changeux model after 50 years. Annu Rev Biophys 41: 103-133.