MUC1 in macrophage: Contributions to cigarette smoke-induced lung cancer

Cancer Research

Volumn 74, Issue 2, 2014, Pages 460-470

  Xu, Xiuling ^a   Padilla, Mabel T ^a   Li, Bilan ^a   Wells, Alexandria ^a   Kato, Kosuke ^b   Tellez, Carmen ^a   Belinsky, Steven A ^a   Kim, Kwang Chul ^b   Lin, Yong ^a  

^a LOVELACE RESPIRATORY RESEARCH INSTITUTE   (United States)

^b TEMPLE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CIGARETTE SMOKE; MITOGEN ACTIVATED PROTEIN KINASE; MUCIN 1; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; RNA; TUMOR NECROSIS FACTOR ALPHA; TUMOR NECROSIS FACTOR ALPHA CONVERTING ENZYME;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL TRANSFORMATION; CONTROLLED STUDY; CYTOKINE RELEASE; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME REPRESSION; HUMAN; HUMAN CELL; LUNG ALVEOLUS EPITHELIUM; LUNG ALVEOLUS MACROPHAGE; LUNG CANCER; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RNA INTERFERENCE; SMOKING; TOBACCO; TUMOR MICROENVIRONMENT;

ANIMALS; CELL SURVIVAL; CELLS, CULTURED; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; INFLAMMATION; LUNG NEOPLASMS; MACROPHAGES; MICE; MUCIN-1; RNA INTERFERENCE; SMOKE; SMOKING; TOBACCO; TUMOR NECROSIS FACTOR-ALPHA; U937 CELLS;

EID: 84892942554     PISSN: 00085472     EISSN: 15387445     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-13-1713     Document Type: Article

References (35)

1. Lin WW, Karin M. A cytokine-mediated link between innate immunity, inflammation, and cancer. J Clin Invest 2007;117:1175-83.
2. Cho WC, Kwan CK, Yau S, So PP, Poon PC, Au JS. The role of inflammation in the pathogenesis of lung cancer. Expert Opin on Ther Target 2011;15:1127-37.
3. Milara J, Cortijo J. Tobacco, inflammation, and respiratory tract cancer. Curr Pharm Des 2012;18:3901-38.
4. Hecht SS. Tobaccosmoke carcinogens and lungcancer. JNatlCancer Inst 1999;91:1194-210.
5. Belinsky SA. Gene-promoter hypermethylation as a biomarker in lung cancer. Nat Rev Cancer 2004;4:707-17.
6. Pfeifer GP, Denissenko MF, Olivier M, Tretyakova N, Hecht SS, Hainaut P. Tobacco smoke carcinogens, DNA damage and p53 mutations in smoking-associated cancers. Oncogene 2002;21:7435-51.
7. Aggarwal BB. Signalling pathways of the TNF superfamily: a doubleedged sword. Nat Rev Immunol 2003;3:745-56.
8. Wang X, Lin Y. Tumor necrosis factor and cancer, buddies or foes? Acta Pharmacol Sin 2008;29:1275-88.
9. Gonda TA, Tu S, Wang TC. Chronic inflammation, the tumor microenvironment and carcinogenesis. Cell Cycle 2009;8:2005-13.
10. Lu W, Hisatsune A, Koga T, Kato K, Kuwahara I, Lillehoj EP, et al. Cutting edge: enhanced pulmonary clearance of Pseudomonas aeruginosa by Muc1 knockout mice. J Immunol 2006;176:3890-4.
11. Kyo Y, Kato K, Park YS, Gajghate S, Umehara T, Lillehoj EP, et al. Antiinflammatory role of MUC1 mucin during infection with nontypeable Haemophilus influenzae. Am J Respir Cell Mol Biol 2012;46:149-56.
12. Hattrup CL, Gendler SJ. Structure and function of the cell surface (tethered) mucins. Annu Rev Physiol 2008;70:431-57.
13. Kufe DW. MUC1-C oncoprotein as a target in breast cancer: activation of signaling pathways and therapeutic approaches. Oncogene 2012;32:1073-81.
14. Baldus SE, Engelmann K, Hanisch FG. MUC1 and the MUCs: a family of human mucins with impact in cancer biology. Crit Rev Clin Lab Sci 2004;41:189-231.
15. Woenckhaus M, Merk J, Stoehr R, Schaeper F, Gaumann A, Wiebe K, et al. Prognostic value of FHIT, CTNNB1, and MUC1 expression in non-small cell lung cancer. Hum Pathol 2008;39:126-36.
16. Schroeder JA, Masri AA, Adriance MC, Tessier JC, Kotlarczyk KL, Thompson MC, et al. MUC1 overexpression results in mammary gland tumorigenesis and prolonged alveolar differentiation. Oncogene 2004;23:5739-47.
17. Guddo F, Giatromanolaki A, Koukourakis MI, Reina C, Vignola AM, Chlouverakis G, et al. MUC1 (episialin) expression in non-small cell lung cancer is independent of EGFR and c-erbB-2 expression and correlates with poor survival in node positive patients. J Clin Pathol 1998;51:667-71.
18. Xu X, Bai L, Chen W, Padilla MT, Liu Y, Kim KC, et al. MUC1 contributes to BPDE-induced human bronchial epithelial cell transformation through facilitating EGFR activation. PLoS ONE 2012;7:e33846.
19. Koga T, Kuwahara I, Lillehoj EP, Lu W, Miyata T, Isohama Y, et al. TNF-alpha induces MUC1 gene transcription in lung epithelial cells: its signaling pathway and biological implication. Am J Physiol Lung Cell Mol Physiol 2007;293:L693-701.
20. Correa I, Plunkett T, Vlad A, Mungul A, Candelora-Kettel J, Burchell JM, et al. Form and pattern of MUC1 expression on T cells activated in vivo or in vitro suggests a function in T-cell migration. Immunology 2003;108:32-41.
21. Taki C, Kitajima S, Sueyoshi K, Yonezawa S, Tanaka S, Sakoda K, et al. MUC1 mucin expression in follicular dendritic cells and lymphoepithelial lesions of gastric mucosa-associated lymphoid tissue lymphoma. Pathol Int 2002;52:691-701.
22. Wang Q, Chen W, Xu X, Li B, He W, Padilla MT, et al. RIP1 potentiates BPDE-induced transformation in human bronchial epithelial cells through catalase-mediated suppression of excessive reactive oxygen species. Carcinogenesis 2013;34:2119-28.
23. Ramirez RD, Sheridan S, Girard L, Sato M, Kim Y, Pollack J, et al. Immortalization of human bronchial epithelial cells in the absence of viral oncoproteins. Cancer Res 2004;64:9027-34.
24. Chen W, Xu X, Bai L, Padilla MT, Gott KM, Leng S, et al. Low-dose gamma-irradiation inhibits IL-6 secretion from human lung fibroblasts that promotes bronchial epithelial cell transformation by cigarettesmoke carcinogen. Carcinogenesis 2012;33:1368-74.
25. March TH, Wilder JA, Esparza DC, Cossey PY, Blair LF, Herrera LK, et al. Modulators of cigarette smoke-induced pulmonary emphysema in A/J mice. Toxicol Sci 2006;92:545-59.
26. Park YS, Guang W, Blanchard TG, Chul Kim K, Lillehoj EP. Suppression of IL-8 production in gastric epithelial cells by MUC1 mucin and peroxisome proliferator-associated receptor-gamma. Am J Physiol 2012;303:G765-74.
27. Park YS, Lillehoj EP, Kato K, Park CS, Kim KC. PPARgamma inhibits airway epithelialcell inflammatoryresponsethroughaMUC1-dependent mechanism. Am J Physiol Lung Cell Mol Physiol 2012;302:L679-87.
28. Kuwahara I, Lillehoj EP, Koga T, Isohama Y, Miyata T, Kim KC. The signaling pathway involved in neutrophil elastase stimulated MUC1 transcription. Am J Respir Cell Mol Biol 2007;37:691-8.
29. Shalom-Barak T, Nicholas JM, Wang Y, Zhang X, Ong ES, Young TH, et al. Peroxisome proliferator-activated receptor gamma controls Muc1 transcription in trophoblasts. Mol Cell Biol 2004;24:10661-9.
30. Mullberg J, Althoff K, Jostock T, Rose-John S. The importance of shedding of membrane proteins for cytokine biology. Eur Cytokine Netw 2000;11:27-38.
31. Nakamuta M, Enjoji M, Uchimura K, Ohta S, Sugimoto R, Kotoh K, et al. Bisphenol a diglycidyl ether (BADGE) suppresses tumor necrosis factor-alpha production as a PPARgamma agonist in the murine macrophage-like cell line, RAW 264.7. Cell Biol Int 2002;26:235-41.
32. Amoruso A, Bardelli C, Gunella G, Fresu LG, Ferrero V, Brunelleschi S. Quantification of PPAR-gamma protein in monocyte/macrophages from healthy smokers and non-smokers: a possible direct effect of nicotine. Life Sci 2007;81:906-15.
33. Ueno K, Koga T, Kato K, Golenbock DT, Gendler SJ, Kai H, et al. MUC1 mucin is a negative regulator of toll-like receptor signaling. Am J Respir Cell Mol Biol 2008;38:263-8.
34. Shen Y, Chen L, Wang T, Wen F. PPARgamma as a potential target to treat airway mucus hypersecretion in chronic airway inflammatory diseases. PPAR Res 2012;2012:256874.
35. Caito S, Yang SR, Kode A, Edirisinghe I, Rajendrasozhan S, Phipps RP, et al. Rosiglitazone and 15-deoxy-Delta12, 14-prostaglandin J2, PPARgamma agonists, differentially regulate cigarette smoke-mediated pro-inflammatory cytokine release in monocytes/macrophages. Antioxid Redox Signal 2008;10:253-60.