Gray matter atrophy and freezing of gait in Parkinson's disease: Is the evidence black-on-white?

Movement Disorders

Volumn 29, Issue 1, 2014, Pages 134-139

  Herman, Talia ^a,b   Rosenberg Katz, Keren ^a   Jacob, Yael ^a   Giladi, Nir ^a,b   Hausdorff, Jeffrey M ^a,b,c  

^a TEL AVIV SOURASKY MEDICAL CENTER   (Israel)

^b TEL AVIV UNIVERSITY   (Israel)

^c HARVARD MEDICAL SCHOOL   (United States)

Author keywords

Freezing of gait; Gray matter; Parkinson's disease; Volumetric MRI

Indexed keywords

ADULT; ANGULAR GYRUS; ARTICLE; BRAIN ATROPHY; BRAIN SIZE; CAUDATE NUCLEUS; COGNITION; FEMALE; FREEZING; FREEZING OF GAIT; GAIT; GRAY MATTER; GRAY MATTER ATROPHY; HUMAN; MAJOR CLINICAL STUDY; MALE; MIDDLE AGED; NUCLEAR MAGNETIC RESONANCE IMAGING; PARIETAL LOBE; PARKINSON DISEASE; PRIORITY JOURNAL; VOXEL BASED MORPHOMETRY;

FREEZING OF GAIT; GRAY MATTER; PARKINSON'S DISEASE; VOLUMETRIC MRI;

AGED; BRAIN; COGNITION; FEMALE; GAIT; GAIT DISORDERS, NEUROLOGIC; HUMANS; MAGNETIC RESONANCE IMAGING; MALE; MIDDLE AGED; NERVE FIBERS, UNMYELINATED; NEUROPSYCHOLOGICAL TESTS; PARKINSON DISEASE;

EID: 84892906891     PISSN: 08853185     EISSN: 15318257     Source Type: Journal    
DOI: 10.1002/mds.25697     Document Type: Article

References (40)

1. Bloem BR, Hausdorff JM, Visser JE, Giladi N. Falls and freezing of gait in Parkinson's disease: a review of two interconnected, episodic phenomena. Mov Disord 2004;19:871-884.
2. Giladi N, Nieuwboer A. Understanding and treating freezing of gait in parkinsonism, proposed working definition, and setting the stage. Mov Disord 2008;23(Suppl 2):S423-S425.
3. Moore O, Peretz C, Giladi N. Freezing of gait affects quality of life of peoples with Parkinson's disease beyond its relationships with mobility and gait. Mov Disord 2007;22:2192-2195.
4. Nutt JG, Bloem BR, Giladi N, Hallett M, Horak FB, Nieuwboer A. Freezing of gait: moving forward on a mysterious clinical phenomenon. Lancet Neurol 2011;10:734-744.
5. Plotnik M, Giladi N, Hausdorff JM. Bilateral coordination of walking and freezing of gait in Parkinson's disease. Eur J Neurosci 2008;27:1999-2006.
6. Spildooren J, Vercruysse S, Desloovere K, Vandenberghe W, Kerckhofs E, Nieuwboer A. Freezing of gait in Parkinson's disease: the impact of dual-tasking and turning. Mov Disord 2010;25:2563-2570.
7. Snijders AH, Haaxma CA, Hagen YJ, Munneke M, Bloem BR. Freezer or non-freezer: clinical assessment of freezing of gait. Parkinsonism Relat Disord 2012;18:149-154.
8. Plotnik M, Giladi N, Hausdorff JM. Bilateral coordination of gait and Parkinson's disease: the effects of dual tasking. J Neurol Neurosurg Psychiatry 2009;80:347-350.
9. Shine JM, Naismith SL, Palavra NC, et al. Attentional set-shifting deficits correlate with the severity of freezing of gait in Parkinson's disease. Parkinsonism Relat Disord 2013;19:388-390.
10. Naismith SL, Shine JM, Lewis SJ. The specific contributions of set-shifting to freezing of gait in Parkinson's disease. Mov Disord 2010;25:1000-1004.
11. Amboni M, Cozzolino A, Longo K, Picillo M, Barone P. Freezing of gait and executive functions in patients with Parkinson's disease. Mov Disord 2008;23:395-400.
12. Lewis SJ, Barker RA. A pathophysiological model of freezing of gait in Parkinson's disease. Parkinsonism Relat Disord 2009;15:333-338.
13. Tessitore A, Amboni M, Cirillo G, et al. Regional gray matter atrophy in patients with Parkinson disease and freezing of gait. AJNR Am J Neuroradiol 2012;33:1804-1809.
14. Kostic VS, Agosta F, Pievani M, et al. Pattern of brain tissue loss associated with freezing of gait in Parkinson disease. Neurology 2012;78:409-416.
15. Snijders AH, Leunissen I, Bakker M et al. Gait-related cerebral alterations in patients with Parkinson's disease with freezing of gait. Brain 2011;134:59-72.
16. Rosenberg-Katz K, Herman T, Jacob Y, Giladi N, Hendler T, Hausdorff JM. Gray matter atrophy distinguishes between Parkinson disease motor subtypes. Neurology 2013;80:1476-1484.
17. Nieuwboer A, Rochester L, Herman T, et al. Reliability of the new freezing of gait questionnaire: agreement between patients with Parkinson's disease and their carers. Gait Posture 2009;30:459-463.
18. Fahn S, Elton R; Members of the UPDRS development committee. Unified Parkinson's disease rating scale. In: Fahn S, Marsden CD, Calne D, Goldstein M, eds. Recent Developments in Parkinson's Disease. Florham Park, NJ: Macmillan Health Care Information; 1987:153-163.
19. Berg KO, Wood-Dauphinee SL, Williams JI, Maki B. Measuring balance in the elderly: validation of an instrument. Can J Public Health 1992;83(Suppl 2):S7-S11.
20. Yesavage JA, Brink TL, Rose TL, et al. Development and validation of a geriatric depression screening scale: a preliminary report. J Psychiatr Res 1982;17:37-49.
21. Powell LE, Myers AM. The Activities-specific Balance Confidence (ABC) Scale. J Gerontol A Biol Sci Med Sci 1995;50A:M28-M34.
22. Yogev G, Giladi N, Peretz C, Springer S, Simon ES, Hausdorff JM. Dual tasking, gait rhythmicity, and Parkinson's disease: which aspects of gait are attention demanding? Eur J Neurosci 2005;22:1248-1256.
23. Hausdorff JM, Yogev G, Springer S, Simon ES, Giladi N. Walking is more like catching than tapping: gait in the elderly as a complex cognitive task. Exp Brain Res 2005;164:541-548.
24. Dwolatzky T, Whitehead V, Doniger GM, et al. Validity of the Mindstreams computerized cognitive battery for mild cognitive impairment. J Mol Neurosci 2004;24:33-44.
25. Nasreddine ZS, Phillips NA, Bedirian V, et al. The Montreal Cognitive Assessment, MoCA: a brief screening tool for mild cognitive impairment. J Am Geriatr Soc 2005;53:695-699.
26. Dubois B, Slachevsky A, Litvan I, Pillon B. The FAB: a Frontal Assessment Battery at bedside. Neurology 2000;55:1621-1626.
27. Kave G. The development of naming and word fluency: evidence from Hebrew-speaking children between ages 8 and 17. Dev Neuropsychol 2006;29:493-508.
28. Tomlinson CL, Stowe R, Patel S, Rick C, Gray R, Clarke CE. Systematic review of levodopa dose equivalency reporting in Parkinson's disease. Mov Disord 2010;25:2649-2653.
29. Bartels AL, de Jong BM, Giladi N, et al. Striatal dopa and glucose metabolism in PD patients with freezing of gait. Mov Disord 2006;21:1326-1332.
30. Shine JM, Matar E, Ward PB, et al. Exploring the cortical and subcortical functional magnetic resonance imaging changes associated with freezing in Parkinson's disease. Brain 2013;136:1204-1215.
31. Thaler A, Mirelman A, Helmich RC, et al. Neural correlates of executive functions in healthy G2019S LRRK2 mutation carriers. Cortex 2013 Jan 7. doi: 10.1016/j.cortex.2012.12.017.
32. Seghier ML. The angular gyrus: multiple functions and multiple subdivisions. Neuroscientist 2013;19:43-61.
33. Caspers S, Schleicher A, Bacha-Trams M, Palomero-Gallagher N, Amunts K, Zilles K. Organization of the human inferior parietal lobule based on receptor architectonics. Cereb Cortex 2013;23:615-628.
34. Vandenbossche J, Deroost N, Soetens E, et al. Freezing of gait in Parkinson disease is associated with impaired conflict resolution. Neurorehabil Neural Repair 2011;25:765-773.
35. Giladi N, Hausdorff JM. The role of mental function in the pathogenesis of freezing of gait in Parkinson's disease. J Neurol Sci 2006;248:173-176.
36. Shima K, Mushiake H, Saito N, Tanji J. Role for cells in the presupplementary motor area in updating motor plans. Proc Natl Acad Sci U S A 1996;93:8694-8698.
37. Lau HC, Rogers RD, Haggard P, Passingham RE. Attention to intention. Science 2004;303:1208-1210.
38. Shine JM, Moore ST, Bolitho SJ, et al. Assessing the utility of Freezing of Gait Questionnaires in Parkinson's Disease. Parkinsonism Relat Disord 2012;18:25-29.
39. Grahn JA, Parkinson JA, Owen AM. The cognitive functions of the caudate nucleus. Prog Neurobiol 2008;86:141-155.
40. Heremans E, Nieuwboer A, Spildooren J, et al. Cognitive aspects of freezing of gait in Parkinson's disease: a challenge for rehabilitation. J Neural Transm 2013;120:543-557.