Gait-related cerebral alterations in patients with Parkinson's disease with freezing of gait

Brain

Volumn 134, Issue 1, 2011, Pages 59-72

  Snijders, Anke H ^a,b   Leunissen, Inge ^a,b   Bakker, Maaike ^a,b   Overeem, Sebastiaan ^b   Helmich, Rick C ^a,b   Bloem, Bastiaan R ^b   Toni, Ivan ^a,c  

^a RADBOUD UNIVERSITY   (Netherlands)

^b RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

^c RADBOUD UNIVERSITY NIJMEGEN   (Netherlands)

Author keywords

gait; motor planning; Parkinsons disease; pedunculopontine nucleus

Indexed keywords

ANTIPARKINSON AGENT;

ADULT; ARTICLE; BRAIN ATROPHY; CLINICAL ARTICLE; CONTROLLED STUDY; DISEASE DURATION; ELECTROENCEPHALOGRAM; ELECTROMYOGRAPHY; FEMALE; FREEZING OF GAIT; FUNCTIONAL MAGNETIC RESONANCE IMAGING; GAIT DISORDER; GRAY MATTER; HUMAN; MALE; MOTOR ACTIVITY; NEUROIMAGING; PARKINSON DISEASE; PRIORITY JOURNAL; SOMATOSENSORY SYSTEM; TASK PERFORMANCE; VOXEL BASED MORPHOMETRY; WALKING;

AGED; ANALYSIS OF VARIANCE; BRAIN; BRAIN MAPPING; FEMALE; GAIT; GAIT DISORDERS, NEUROLOGIC; HUMANS; IMAGE PROCESSING, COMPUTER-ASSISTED; IMAGINATION; MAGNETIC RESONANCE IMAGING; MALE; MIDDLE AGED; PARKINSON DISEASE; QUESTIONNAIRES;

EID: 78650681586     PISSN: 00068950     EISSN: 14602156     Source Type: Journal    
DOI: 10.1093/brain/awq324     Document Type: Article

References (69)

1. Almeida QJ, Frank JS, Roy EA, Jenkins ME, Spaulding S, Patla AE, et al. An evaluation of sensorimotor integration during locomotion toward a target in Parkinson's disease. Neuroscience 2005; 134: 283-93.
2. Ashburner J, Friston KJ. Voxel-based morphometry-the methods. Neuroimage 2000; 11: 805-21.
3. Bakker M, de Lange FP, Helmich RC, Scheeringa R, Bloem BR, Toni I. Cerebral correlates of motor imagery of normal and precision gait. Neuroimage 2008; 41: 998-1010.
4. Bakker M, de Lange FP, Stevens JA, Toni I, Bloem BR. Motor imagery of gait: a quantitative approach. Exp Brain Res 2007a; 179: 497-504.
5. Bakker M, Verstappen CC, Bloem BR, Toni I. Recent advances in functional neuroimaging of gait. J Neural Transm 2007b; 114: 1323-31.
6. Ballanger B, Lozano AM, Moro E, van ET, Hamani C, Chen R, et al. Cerebral blood flow changes induced by pedunculopontine nucleus stimulation in patients with advanced Parkinson's disease: A [(15)O] H(2)O PET study. Hum Brain Mapp 2009; 30: 3901-9.
7. Bartels AL, de Jong BM, Giladi N, Schaafsma JD, Maguire RP, Veenma L, et al. Striatal dopa and glucose metabolism in PD patients with freezing of gait. Mov Disord 2006; 21: 1326-32.
8. Blakemore SJ, Sirigu A. Action prediction in the cerebellum and in the parietal lobe. Exp Brain Res 2003; 153: 239-45.
9. Bloem BR, Hausdorff JM, Visser JE, Giladi N. Falls and freezing in Parkinson's disease: a review of two interconnected, episodic phenomena. Mov Disord 2004; 19: 871-84.
10. Braak H, Rub U, Sandmann-Keil D, Gai WP, de Vos RA, Jansen Steur EN, et al. Parkinson's disease: affection of brain stem nuclei controlling premotor and motor neurons of the somatomotor system. Acta Neuropathol 2000; 99: 489-95.
11. Buhmann C, Binkofski F, Klein C, Buchel C, van ET, Erdmann C, et al. Motor reorganization in asymptomatic carriers of a single mutantParkin allele: a human model for presymptomatic parkinsonism. Brain 2005; 128: 2281-90.
12. Chee R, Murphy A, Danoudis M, Georgiou-Karistianis N, Iansek R. Gait freezing in Parkinson's disease and the stride length sequence effect interaction. Brain 2009; 132: 2151-60.
13. Cisek P, Kalaska JF. Neural correlates of mental rehearsal in dorsal pre-motor cortex. Nature 2004; 431: 993-6.
14. de Lange FP, Helmich RC, Toni I. Posture influences motor imagery: an fMRI study. Neuroimage 2006; 33: 609-17.
15. Duvernoy HM, Cabanis EA, Vannson JL. The human brain: surface, and three-dimensional sectional anatomy and MRI. Vienna: Springer; 1991.
16. Eickhoff SB, Stephan KE, Mohlberg H, Grefkes C, Fink GR, Amunts K, et al. A new SPM toolbox for combining probabilistic cytoarchitectonic maps and functional imaging data. Neuroimage 2005; 25: 1325-35.
17. Eippert F, Bingel U, Schoell ED, Yacubian J, Klinger R, Lorenz J, et al. Activation of the opioidergic descending pain control system underlies placebo analgesia. Neuron 2009; 63: 533-43.
18. Fabre N, Brefel C, Sabatini U, Celsis P, Montastruc JL, Chollet F, et al. Normal frontal perfusion in patients with frozen gait. Mov Disord 1998; 13: 677-83.
19. Fasano A, Piano C, De SC, Cioni B, Di GD, Zinno M, et al. High frequency extradural motor cortex stimulation transiently improves axial symptoms in a patient with Parkinson's disease. Mov Disord 2008; 23: 1916-19.
20. Ferraye MU, Debu B, Fraix V, Goetz L, Ardouin C, Yelnik J, et al. Effects of pedunculopontine nucleus area stimulation on gait disorders in Parkinson's disease. Brain 2010; 133: 205-14.
21. Field A. Discovering statistics using SPSS. London: SAGE publications Ltd; 2009.
22. Fink GR, Frackowiak RS, Pietrzyk U, Passingham RE. Multiple nonprim-ary motor areas in the human cortex. J Neurophysiol 1997; 77: 2164-74.
23. Friston KJ, Holmes AP, Poline JB, Grasby PJ, Williams SC, Frackowiak RS, et al. Analysis of fMRI time-series revisited. Neuroimage 1995; 2: 45-53.
24. Friston KJ, Holmes A, Poline JB, Price CJ, Frith CD. Detecting activations in PET and fMRI: levels of inference and power. Neuroimage 1996; 4: 223-35.
25. Gentili R, Cahouet V, Ballay Y, Papaxanthis C. Inertial properties of the arm are accurately predicted during motor imagery. Behav Brain Res 2004; 155: 231-9.
26. Hanakawa T, Katsumi Y, Fukuyama H, Honda M, Hayashi T, Kimura J, et al. Mechanisms underlying gait disturbance in Parkinson's disease: a single photon emission computed tomography study. Brain 1999; 122 (Pt 7): 1271-82.
27. Hathout GM, Bhidayasiri R. Midbrain ataxia: an introduction to the mes-encephalic locomotor region and the pedunculopontine nucleus. AJR Am J Roentgenol 2005; 184: 953-6.
28. Hausdorff JM, Schaafsma JD, Balash Y, Bartels AL, Gurevich T, Giladi N. Impaired regulation of stride variability in Parkinson's disease subjects with freezing of gait. Exp Brain Res 2003; 149: 187-94.
29. Helmich RC, Aarts E, de Lange FP, Bloem BR, Toni I. Increased dependence of action selection on recent motor history in Parkinson's disease. J Neurosci 2009; 29: 6105-13.
30. Hughes AJ, Daniel SE, Kilford L, Lees AJ. Accuracy of clinical diagnosis of idiopathic Parkinson's disease: a clinico-pathological study of 100 cases. J Neurol Neurosurg Psychiatry 1992; 55: 181-4.
31. Isaac I, Marks DF, Russell DG. An instrument for assessing imagery of movement: the vividness of movement imagery questionnaire (VMIQ). J Ment Imag 1986; 23-30.
32. Iseki K, Hanakawa T, Hashikawa K, Tomimoto H, Nankaku M, Yamauchi H, Hallett M, Fukuyama H. Gait disturbance associated with white matter changes: a gait analysis and blood flow study. Neuroimage 2010; 49: 1659-66.
33. Jacobs JV, Lou JS, Kraakevik JA, Horak FB. The supplementary motor area contributes to the timing of the anticipatory postural adjustment during step initiation in participants with and without Parkinson's disease. Neuroscience 2009a; 164: 877-85.
34. Jacobs JV, Nutt JG, Carlson-Kuhta P, Stephens M, Horak FB. Knee trembling during freezing of gait represents multiple anticipatory posturaladjustments. Exp Neurol 2009b; 215: 334-41.
35. Jahn K, Deutschlander A, Stephan T, Kalla R, Wiesmann M, Strupp M,et al. Imaging human supraspinal locomotor centers in brainstem andcerebellum. Neuroimage 2008; 39: 786-92.
36. Jeannerod M. The representing brain: neural correlates of motor intention and imagery. Behavioral Brain Sciences 1994; 17: 187-245.
37. Jordan LM. Initiation of locomotion in mammals. Ann N Y Acad Sci1998; 860: 83-93.
38. Kaas A, Weigelt S, Roebroeck A, Kohler A, Muckli L. Imagery of amoving object: the role of occipital cortex and human MT/V5+.Neuroimage 2010; 49: 794-804.
39. Keijsers NL, Admiraal MA, Cools AR, Bloem BR, Gielen CC. Differentialprogression of proprioceptive and visual information processing deficitsin Parkinson's disease. Eur J Neurosci 2005; 21: 239-48.
40. Keren NI, Lozar CT, Harris KC, Morgan PS, Eckert MA. In vivo mappingof the human locus coeruleus. Neuroimage 2009; 47: 1261-7.
41. la Fougere C, Zwergal A, Rominger A, Forster S, Fesl G, Dieterich M,et al. Real versus imagined locomotion: A [(18)F]-FDG PET-fMRI comparison. Neuroimage 2010; 50: 1589-98.
42. Lewis GN, Byblow WD. Altered sensorimotor integration in Parkinson'sdisease. Brain 2002; 125: 2089-99.
43. Macht M, Kaussner Y, Moller JC, Stiasny-Kolster K, Eggert KM,Kruger HP, et al. Predictors of freezing in Parkinson's disease: asurvey of 6,620 patients. Mov Disord 2007; 22: 953-56.
44. Malouin F, Richards CL, Jackson PL, Dumas F, Doyon J. Brain activationsduring motor imagery of locomotor-related tasks: a PET study. HumBrain Mapp 2003; 19: 47-62.
45. Masdeu JC, Alampur U, Cavaliere R, Tavoulareas G. Astasia and gaitfailure with damage of the pontomesencephalic locomotor region.Ann Neurol 1994; 35: 619-21.
46. Matsui H, Udaka F, Miyoshi T, Hara N, Tamaura A, Oda M, et al.Three-dimensional stereotactic surface projection study of freezing ofgait and brain perfusion image in Parkinson's disease. Mov Disord2005; 20: 1272-7.
47. Mayka MA, Corcos DM, Leurgans SE, Vaillancourt DE.Three-dimensional locations and boundaries of motor and premotorcortices as defined by functional brain imaging: a meta-analysis.Neuroimage 2006; 31: 1453-74.
48. Miller KJ, Schalk G, Fetz EE, den NM, Ojemann JG, Rao RP. Corticalactivity during motor execution, motor imagery, and imagery-basedonline feedback. Proc Natl Acad Sci USA 2010; 107: 4430-5.
49. Mulder T, Hochstenbach JB, van Heuvelen MJ, den Otter AR. Motorimagery: the relation between age and imagery capacity. Hum MovSci 2007; 26: 203-11.
50. Nachev P, Kennard C, Husain M. Functional role of the supplementaryand pre-supplementary motor areas. Nat Rev Neurosci 2008; 9:856-69.
51. Nico D, Daprati E, Rigal F, Parsons L, Sirigu A. Left and right handrecognition in upper limb amputees. Brain 2004; 127: 120-32.
52. Nieuwboer A, Dom R, De WW, Desloovere K, Janssens L, Stijn V.Electromyographic profiles of gait prior to onset of freezing episodesin patients with Parkinson's disease. Brain 2004; 127: 1650-60.
53. Nieuwboer A, Rochester L, Herman T, Vandenberghe W, Emil GE,Thomaes T, et al. Reliability of the new freezing of gait questionnaire:agreement between patients with Parkinson's disease and their carers.Gait Posture 2009; 30: 459-63.
54. Pahapill PA, Lozano AM. The pedunculopontine nucleus and Parkinson'sdisease. Brain 2000; 123 (Pt 9): 1767-83.
55. Piallat B, Chabardes S, Torres N, Fraix V, Goetz L, Seigneuret E, et al.Gait is associated with an increase in tonic firing of the sub-cuneiformnucleus neurons. Neuroscience 2009; 158: 1201-5.
56. Picard N, Strick PL. Motor areas of the medial wall: a review oftheir location and functional activation. Cereb Cortex 1996; 6:342-53.
57. Plaha P, Gill SS. Bilateral deep brain stimulation of the pedunculopontinenucleus for Parkinson's disease. Neuroreport 2005; 16: 1883-7.
58. Plotnik M, Giladi N, Hausdorff JM. Bilateral coordination of walking and freezing of gait in Parkinson's disease. Eur J Neurosci 2008; 27: 1999-2006.
59. Price CJ, Friston KJ. Functional imaging studies of neuropsycho-logical patients: applications and limitations. Neurocase 2002; 8: 345-54.
60. Rushworth MF, Hadland KA, Paus T, Sipila PK. Role of the human medial frontal cortex in task switching: a combined fMRI and TMS study. J Neurophysiol 2002; 87: 2577-92.
61. Sabatini U, Boulanouar K, Fabre N, Martin F, Carel C, Colonnese C, et al. Cortical motor reorganization in akinetic patients with Parkinson's disease: a functional MRI study. Brain 2000; 123 (Pt 2): 394-403.
62. Scheperjans F, Eickhoff SB, Homke L, Mohlberg H, Hermann K, Amunts K, et al. Probabilistic maps, morphometry, and variability of cytoarchitectonic areas in the human superior parietal cortex. Cereb Cortex 2008; 18: 2141-57.
63. Snijders AH, Nijkrake MJ, Bakker M, Munneke M, Wind C, Bloem BR. Clinimetrics of freezing of gait. Mov Disord 2008; 23 (Suppl. 2): S468-S474.
64. Stefani A, Lozano AM, Peppe A, Stanzione P, Galati S, Tropepi D, et al. Bilateral deep brain stimulation of the pedunculopontine and subtha-lamic nuclei in severe Parkinson's disease. Brain 2007; 130: 1596-607.
65. Stephan KM, Fink GR, Passingham RE, Silbersweig D, Ceballos-Baumann AO, Frith CD, et al. Functional anatomy of the mental representation of upper extremity movements in healthy subjects. J Neurophysiol 1995; 73: 373-86.
66. Tani N, Saitoh Y, Kishima H, Oshino S, Hatazawa J, Hashikawa K, et al. Motor cortex stimulation for levodopa-resistant akinesia: case report. Mov Disord 2007; 22: 1645-9.
67. Wolpert DM, Goodbody SJ, Husain M. Maintaining internal representations: the role of the human superior parietal lobe. Nat Neurosci 1998; 1: 529-33.
68. Zrinzo L, Zrinzo LV, Tisch S, Limousin PD, Yousry TA, Afshar F, et al. Stereotactic localization of the human pedunculopontine nucleus: atlas-based coordinates and validation of a magnetic resonance imaging protocol for direct localization. Brain 2008; 131: 1588-98.
69. Zweig RM, Jankel WR, Hedreen JC, Mayeux R, Price DL. The peduncu-lopontine nucleus in Parkinson's disease. Ann Neurol 1989; 26: 41-6.