Melanocyte-secreted fibromodulin promotes an angiogenic microenvironment

Journal of Clinical Investigation

Volumn 124, Issue 1, 2014, Pages 425-436

  Adini, Irit ^a   Ghosh, Kaustabh ^b   Adini, Avner ^a   Chi, Zai Long ^a   Yoshimura, Takeru ^a   Benny, Ofra ^a   Connor, Kip M ^c   Rogers, Michael S ^a   Bazinet, Lauren ^a   Birsner, Amy E ^a   Bielenberg, Diane R ^a   D'Amato, Robert J ^a,c  

^a BOSTON CHILDREN S HOSPITAL   (United States)

^b University of California Riverside   (United States)

^c HARVARD MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

FIBROBLAST GROWTH FACTOR 2; FIBROMODULIN; MATRIGEL;

AFRICAN AMERICAN; ALBINO; ANGIOGENESIS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; CORNEA NEOVASCULARIZATION; GENE DELETION; HUMAN; HUMAN CELL; IN VIVO STUDY; MELANOCYTE; MICROENVIRONMENT; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DETERMINATION; PROTEIN FUNCTION; PROTEIN SECRETION; RETINA DEVELOPMENT; SKIN PIGMENTATION; SUBRETINAL NEOVASCULARIZATION; WOUND HEALING;

EID: 84892906083     PISSN: 00219738     EISSN: 15588238     Source Type: Journal    
DOI: 10.1172/JCI69404     Document Type: Article

References (46)

1. Congdon N, et al. Causes and prevalence of visual impairment among adults in the United States. Arch Ophthalmol. 2004;122(4):477-485
2. Gottlieb JL. Age-related macular degeneration. JAMA. 2002;288(18):2233- 2236
3. Vanderbeek BL, Zacks DN, Talwar N, Nan B, Musch DC, Stein JD. Racial differences in agerelated macular degeneration rates in the United States: a longitudinal analysis of a managed care network. Am J Ophthalmol. 2011;152(2):273-282.e3
4. Abdel-Malek Z, et al. Mitogenic and melanogenic stimulation of normal human melanocytes by melanotropic peptides. Proc Natl Acad Sci U S A. 1995; 92(5):1789-1793
5. Hu DN, Yu GP, McCormick SA, Schneider S, Finger PT. Population-based incidence of uveal melanoma in various races and ethnic groups. Am J Ophthalmol. 2005;140(4):612-617
6. Weis E, Shah CP, Lajous M, Shields JA, Shields CL. The association between host susceptibility factors and uveal melanoma: a meta-Analysis. Arch Ophthalmol. 2006;124(1):54-60
7. Costin GE, Hearing VJ. Human skin pigmentation: melanocytes modulate skin color in response to stress. FASEB J. 2007;21(4):976-994
8. Sarangarajan R, Apte SP. Melanization and phagocytosis: implications for age related macular degeneration. Mol Vis. 2005;11:482-490
9. Abdel-Malek Z, Swope V, Smalara D, Babcock G, Dawes S, Nordlund J. Analysis of the UV-induced melanogenesis and growth arrest of human melanocytes. Pigment Cell Res. 1994;7(5):326-332
10. Fedorow H, Tribl F, Halliday G, Gerlach M, Riederer P, Double KL. Neuromelanin in human dopamine neurons: comparison with peripheral melanins and relevance to Parkinson's disease. Prog Neurobiol. 2005;75(2):109-124
11. Galibert MD, Carreira S, Goding CR. The Usf-1 transcription factor is a novel target for the stress-responsive p38 kinase and mediates UV-induced Tyrosinase expression. EMBO J. 2001;20(17):5022-5031
12. Hornyak TJ, Hayes DJ, Ziff EB. Cell-density-dependent regulation of expression and glycosylation of dopachrome tautomerase/tyrosinase-related protein- 2. J Invest Dermatol. 2000;115(1):106-112
13. Kobayashi T, et al. Tyrosinase related protein 1 (TRP1) functions as a DHICA oxidase in melanin biosynthesis. EMBO J. 1994;13(24):5818-5825
14. Benedito E, et al. Melanin formation in the inner ear is catalyzed by a new tyrosine hydroxylase kinetically and structurally different from tyrosinase. Biochim Biophys Acta. 1997;1336(1):59-72
15. Englaro W, et al. Inhibition of the mitogen-Activated protein kinase pathway triggers B16 melanoma cell differentiation. J Biol Chem. 1998;273(16):9966-9970
16. Winder A, et al. The tyrosinase gene family - interactions of melanogenic proteins to regulate melanogenesis. Cell Mol Biol Res. 1994;40(7-8):613-626
17. Yokoyama K, Suzuki H, Yasumoto K, Tomita Y, Shibahara S. Molecular cloning and functional analysis of a cDNA coding for human DOPAchrome tautomerase/tyrosinase-related protein-2. Biochim Biophys Acta. 1994;1217(3):317-321
18. Rohan RM, Fernandez A, Udagawa T, Yuan J, D'Amato RJ. Genetic heterogeneity of angiogenesis in mice. FASEB J. 2000;14(7):871-876
19. Folkman J, Haudenschild CC, Zetter BR. Longterm culture of capillary endothelial cells. Proc Natl Acad Sci U S A. 1979;76(10):5217-5221
20. Alexeev V, Yoon K. Stable and inheritable changes in genotype and phenotype of albino melanocytes induced by an RNA-DNA oligonucleotide. Nat Biotechnol. 1998;16(13):1343-1346
21. Hedbom E, Heinegard D. Interaction of a 59-kDa connective tissue matrix protein with collagen I and collagen II. J Biol Chem. 1989;264(12):6898-6905
22. Oldberg A, Antonsson P, Lindblom K, Heinegard D. A collagen-binding 59-kd protein (fibromodulin) is structurally related to the small interstitial proteoglycans PG-S1 and PG-S2 (decorin). EMBO J. 1989;8(9):2601-2604
23. Svensson L, Narlid I, Oldberg A. Fibromodulin and lumican bind to the same region on collagen type I fibrils. FEBS Lett. 2000;470(2):178-182
24. Sjoberg AP, et al. The factor H variant associated with age-related macular degeneration (His-384) and the non-disease-Associated form bind differentially to C-reactive protein, fibromodulin, DNA, and necrotic cells. J Biol Chem. 2007;282(15):10894-10900
25. Ameye L, Aria D, Jepsen K, Oldberg A, Xu T, Young MF. Abnormal collagen fibrils in tendons of biglycan/ fibromodulin-deficient mice lead to gait impairment, ectopic ossification, and osteoarthritis. FASEB J. 2002;16(7):673-680
26. Ameye L, Young MF. Mice deficient in small leucine- rich proteoglycans: novel in vivo models for osteoporosis, osteoarthritis, Ehlers-Danlos syndrome, muscular dystrophy, and corneal diseases. Glycobiology. 2002;12(9):107R-116R
27. Antonsson P, Heinegard D, Oldberg A. Posttranslational modifications of fibromodulin. J Biol Chem. 1991;266(25):16859-16861
28. Chakravarti S. Functions of lumican and fibromodulin: lessons from knockout mice. Glycoconj J. 2002;19(4-5):287-293
29. Ezura Y, Chakravarti S, Oldberg A, Chervoneva I, Birk DE. Differential expression of lumican and fibromodulin regulate collagen fibrillogenesis in developing mouse tendons. J Cell Biol. 2000; 151(4):779-788
30. Gori F, Schipani E, Demay MB. Fibromodulin is expressed by both chondrocytes and osteoblasts during fetal bone development. J Cell Biochem. 2001; 82(1):46-57
31. Hedlund H, Mengarelli-Widholm S, Heinegard D, Reinholt FP, Svensson O. Fibromodulin distribution and association with collagen. Matrix Biol. 1994; 14(3):227-232
32. Skerka C, et al. Defective complement control of factor H (Y402H) and FHL-1 in age-related macular degeneration. Mol Immunol. 2007;44(13):3398-3406
33. Prota G. Regulatory mechanisms of melanogenesis: beyond the tyrosinase concept. J Invest Dermatol. 1993;100(2 suppl):156S-161S
34. Hata Y, Rook SL, Aiello LP. Basic fibroblast growth factor induces expression of VEGF receptor KDR through a protein kinase C and p44/p42 mitogen- activated protein kinase-dependent pathway. Diabetes. 1999;48(5):1145-1155
35. Ley CD, Olsen MW, Lund EL, Kristjansen PE. Angiogenic synergy of bFGF and VEGF is antagonized by Angiopoietin-2 in a modified in vivo Matrigel assay. Microvasc Res. 2004;68(3):161-168
36. Melero-Martin JM, et al. Engineering robust and functional vascular networks in vivo with human adult and cord blood-derived progenitor cells. Circ Res. 2008;103(2):194-202
37. Adini A, Fainaru O, Udagawa T, Connor KM, Folkman J, D'Amato RJ. Matrigel cytometry: a novel method for quantifying angiogenesis in vivo. J Immunol Methods. 2009;342(1-2):78-81
38. Zudaire E, Gambardella L, Kurcz C, Vermeren S. A computational tool for quantitative analysis of vascular networks. PLoS One. 2011;6(11):e27385
39. Zhang H, Sonoda KH, Qiao H, Oshima T, Hisatomi T, Ishibashi T. Development of a new mouse model of branch retinal vein occlusion and retinal neovascularization. Jpn J Ophthalmol. 2007;51(4):251-257
40. Soo C, et al. Differential expression of fibromodulin, a transforming growth factor-beta modulator, in fetal skin development and scarless repair. Am J Pathol. 2000;157(2):423-433
41. Oh SP, et al. Activin receptor-like kinase 1 modulates transforming growth factor-beta 1 signaling in the regulation of angiogenesis. Proc Natl Acad Sci U S A. 2000;97(6):2626-2631
42. Shao ES, Lin L, Yao Y, Bostrom KI. Expression of vascular endothelial growth factor is coordinately regulated by the activin-like kinase receptors 1 and 5 in endothelial cells. Blood. 2009; 114(10):2197-2206
43. Schonherr E, et al. Decorin deficiency leads to impaired angiogenesis in injured mouse cornea. J Vasc Res. 2004;41(6):499-508
44. Oldberg A, et al. Collagen-binding proteoglycan fibromodulin can determine stroma matrix structure and fluid balance in experimental cancinoma. Proc Natl Acad Sci U S A. 2007;104(35):13966-13971
45. Satchi-Fainaro R, et al. Inhibition of vessel permeability by TNP-470 and its polymer conjugate, caplostatin. Cancer Cell. 2005;7(3):251-261
46. Rogers MS, Birsner AE, D'Amato RJ. The mouse cornea micropocket angiogenesis assay. Nat Protoc. 2007;2(10):2545-2550.