-
1
-
-
34547638047
-
Identification of the transforming EML4-ALK fusion gene in non-small-cell lung cancer
-
Soda M., Choi Y.L., Enomoto M., Takada S., Yamashita Y., Ishikawa S., et al. Identification of the transforming EML4-ALK fusion gene in non-small-cell lung cancer. Nature 2007, 448:561-566.
-
(2007)
Nature
, vol.448
, pp. 561-566
-
-
Soda, M.1
Choi, Y.L.2
Enomoto, M.3
Takada, S.4
Yamashita, Y.5
Ishikawa, S.6
-
2
-
-
84866934606
-
Activity and safety of crizotinib in patients with ALK-positive non-small-cell lung cancer: updated results from a phase 1 study
-
Camidge D.R., Bang Y.J., Kwak E.L., Iafrate A.J., Varella-Garcia M., Fox S.B., et al. Activity and safety of crizotinib in patients with ALK-positive non-small-cell lung cancer: updated results from a phase 1 study. Lancet Oncol 2012, 13:1011-1019.
-
(2012)
Lancet Oncol
, vol.13
, pp. 1011-1019
-
-
Camidge, D.R.1
Bang, Y.J.2
Kwak, E.L.3
Iafrate, A.J.4
Varella-Garcia, M.5
Fox, S.B.6
-
3
-
-
84878347085
-
CH5424802 (RO5424802) for patients with ALK-rearranged advanced non-small-cell lung cancer (AF-001JP study): a single-arm, open-label, phase 1-2 study
-
Seto T., Kiura K., Nishio M., Nakagawa K., Maemondo M., Inoue A., et al. CH5424802 (RO5424802) for patients with ALK-rearranged advanced non-small-cell lung cancer (AF-001JP study): a single-arm, open-label, phase 1-2 study. Lancet Oncol 2013, 14:590-598.
-
(2013)
Lancet Oncol
, vol.14
, pp. 590-598
-
-
Seto, T.1
Kiura, K.2
Nishio, M.3
Nakagawa, K.4
Maemondo, M.5
Inoue, A.6
-
4
-
-
84879071011
-
Crizotinib versus chemotherapy in advanced ALK-positive lung cancer
-
Shaw A.T., Kim D.W., Nakagawa K., Seto T., Crino L., Ahn M.J., et al. Crizotinib versus chemotherapy in advanced ALK-positive lung cancer. N Engl J Med 2013, 368:2385-2394.
-
(2013)
N Engl J Med
, vol.368
, pp. 2385-2394
-
-
Shaw, A.T.1
Kim, D.W.2
Nakagawa, K.3
Seto, T.4
Crino, L.5
Ahn, M.J.6
-
5
-
-
84884993118
-
Clinical activity of the ALK inhibitor LDK378 in advanced, ALK-positive NSCLC
-
[abstr 8010]
-
Shaw A.T., Mehra R., Kim D.W., Felip E., Chow L.Q.M., Camidge D.R., et al. Clinical activity of the ALK inhibitor LDK378 in advanced, ALK-positive NSCLC. J Clin Oncol 2013, 31(Suppl.). [abstr 8010].
-
(2013)
J Clin Oncol
, vol.31
, Issue.SUPPL.
-
-
Shaw, A.T.1
Mehra, R.2
Kim, D.W.3
Felip, E.4
Chow, L.Q.M.5
Camidge, D.R.6
-
6
-
-
48249114422
-
EML4-ALK fusion gene and efficacy of an ALK kinase inhibitor in lung cancer
-
Koivunen J.P., Mermel C., Zejnullahu K., Murphy C., Lifshits E., Holmes A.J., et al. EML4-ALK fusion gene and efficacy of an ALK kinase inhibitor in lung cancer. Clin Cancer Res 2008, 14:4275-4283.
-
(2008)
Clin Cancer Res
, vol.14
, pp. 4275-4283
-
-
Koivunen, J.P.1
Mermel, C.2
Zejnullahu, K.3
Murphy, C.4
Lifshits, E.5
Holmes, A.J.6
-
7
-
-
69349083935
-
Unique clinicopathologic features characterize ALK-rearranged lung adenocarcinoma in the western population
-
Rodig S.J., Mino-Kenudson M., Dacic S., Yeap B.Y., Shaw A., Barletta J.A., et al. Unique clinicopathologic features characterize ALK-rearranged lung adenocarcinoma in the western population. Clin Cancer Res 2009, 15:5216-5223.
-
(2009)
Clin Cancer Res
, vol.15
, pp. 5216-5223
-
-
Rodig, S.J.1
Mino-Kenudson, M.2
Dacic, S.3
Yeap, B.Y.4
Shaw, A.5
Barletta, J.A.6
-
8
-
-
65249095599
-
The EML4-ALK fusion gene is involved in various histologic types of lung cancers from nonsmokers with wild-type EGFR and KRAS
-
Wong D.W., Leung E.L., So K.K., Tam I.Y., Sihoe A.D., Cheng L.C., et al. The EML4-ALK fusion gene is involved in various histologic types of lung cancers from nonsmokers with wild-type EGFR and KRAS. Cancer 2009, 115:1723-1733.
-
(2009)
Cancer
, vol.115
, pp. 1723-1733
-
-
Wong, D.W.1
Leung, E.L.2
So, K.K.3
Tam, I.Y.4
Sihoe, A.D.5
Cheng, L.C.6
-
9
-
-
84863776821
-
Clinicoradiologic characteristics of patients with lung adenocarcinoma harboring EML4-ALK fusion oncogene
-
Fukui T., Yatabe Y., Kobayashi Y., Tomizawa K., Ito S., Hatooka S., et al. Clinicoradiologic characteristics of patients with lung adenocarcinoma harboring EML4-ALK fusion oncogene. Lung Cancer 2012, 77:319-325.
-
(2012)
Lung Cancer
, vol.77
, pp. 319-325
-
-
Fukui, T.1
Yatabe, Y.2
Kobayashi, Y.3
Tomizawa, K.4
Ito, S.5
Hatooka, S.6
-
10
-
-
57349113565
-
Multiplex reverse transcription-PCR screening for EML4-ALK fusion transcripts
-
Takeuchi K., Choi Y.L., Soda M., Inamura K., Togashi Y., Hatano S., et al. Multiplex reverse transcription-PCR screening for EML4-ALK fusion transcripts. Clin Cancer Res 2008, 14:6618-6624.
-
(2008)
Clin Cancer Res
, vol.14
, pp. 6618-6624
-
-
Takeuchi, K.1
Choi, Y.L.2
Soda, M.3
Inamura, K.4
Togashi, Y.5
Hatano, S.6
-
11
-
-
80051784751
-
Detection of ALK gene rearrangement in non-small cell lung cancer: a comparison of fluorescence in situ hybridization and chromogenic in situ hybridization with correlation of ALK protein expression
-
Kim H., Yoo S.B., Choe J.Y., Paik J.H., Xu X., Nitta H., et al. Detection of ALK gene rearrangement in non-small cell lung cancer: a comparison of fluorescence in situ hybridization and chromogenic in situ hybridization with correlation of ALK protein expression. J Thorac Oncol 2011, 6:1359-1366.
-
(2011)
J Thorac Oncol
, vol.6
, pp. 1359-1366
-
-
Kim, H.1
Yoo, S.B.2
Choe, J.Y.3
Paik, J.H.4
Xu, X.5
Nitta, H.6
-
12
-
-
84871986190
-
Immunohistochemistry is a reliable screening tool for identification of ALK rearrangement in non-small-cell lung carcinoma and is antibody dependent
-
Conklin C.M., Craddock K.J., Have C., Laskin J., Couture C., Ionescu D.N. Immunohistochemistry is a reliable screening tool for identification of ALK rearrangement in non-small-cell lung carcinoma and is antibody dependent. J Thorac Oncol 2013, 8:45-51.
-
(2013)
J Thorac Oncol
, vol.8
, pp. 45-51
-
-
Conklin, C.M.1
Craddock, K.J.2
Have, C.3
Laskin, J.4
Couture, C.5
Ionescu, D.N.6
-
13
-
-
80052604399
-
Frequency and clinicopathologic correlates of KRAS amplification in non-small cell lung carcinoma
-
Wagner P.L., Stiedl A.C., Wilbertz T., Petersen K., Scheble V., Menon R., et al. Frequency and clinicopathologic correlates of KRAS amplification in non-small cell lung carcinoma. Lung Cancer 2011, 74:118-123.
-
(2011)
Lung Cancer
, vol.74
, pp. 118-123
-
-
Wagner, P.L.1
Stiedl, A.C.2
Wilbertz, T.3
Petersen, K.4
Scheble, V.5
Menon, R.6
-
14
-
-
69949162760
-
Gefitinib or carboplatin-paclitaxel in pulmonary adenocarcinoma
-
Mok T.S., Wu Y.L., Thongprasert S., Yang C.H., Chu D.T., Saijo N., et al. Gefitinib or carboplatin-paclitaxel in pulmonary adenocarcinoma. N Engl J Med 2009, 361:947-957.
-
(2009)
N Engl J Med
, vol.361
, pp. 947-957
-
-
Mok, T.S.1
Wu, Y.L.2
Thongprasert, S.3
Yang, C.H.4
Chu, D.T.5
Saijo, N.6
-
15
-
-
70349336416
-
Clinical features and outcome of patients with non-small-cell lung cancer who harbor EML4-ALK
-
Shaw A.T., Yeap B.Y., Mino-Kenudson M., Digumarthy S.R., Costa D.B., Heist R.S., et al. Clinical features and outcome of patients with non-small-cell lung cancer who harbor EML4-ALK. J Clin Oncol 2009, 27:4247-4253.
-
(2009)
J Clin Oncol
, vol.27
, pp. 4247-4253
-
-
Shaw, A.T.1
Yeap, B.Y.2
Mino-Kenudson, M.3
Digumarthy, S.R.4
Costa, D.B.5
Heist, R.S.6
-
16
-
-
77953291664
-
The biology and treatment of EML4-ALK non-small cell lung cancer
-
Sasaki T., Rodig S.J., Chirieac L.R., Janne P.A. The biology and treatment of EML4-ALK non-small cell lung cancer. Eur J Cancer 2010, 46:1773-1780.
-
(2010)
Eur J Cancer
, vol.46
, pp. 1773-1780
-
-
Sasaki, T.1
Rodig, S.J.2
Chirieac, L.R.3
Janne, P.A.4
-
17
-
-
84860500563
-
Clinicopathologic implication of ALK rearrangement in surgically resected lung cancer: a proposal of diagnostic algorithm for ALK-rearranged adenocarcinoma
-
Paik J.H., Choi C.M., Kim H., Jang S.J., Choe G., Kim D.K., et al. Clinicopathologic implication of ALK rearrangement in surgically resected lung cancer: a proposal of diagnostic algorithm for ALK-rearranged adenocarcinoma. Lung Cancer 2012, 76:403-409.
-
(2012)
Lung Cancer
, vol.76
, pp. 403-409
-
-
Paik, J.H.1
Choi, C.M.2
Kim, H.3
Jang, S.J.4
Choe, G.5
Kim, D.K.6
-
18
-
-
84655164310
-
EML4-ALK translocation predicts better outcome in lung adenocarcinoma patients with wild-type EGFR
-
Wu S.G., Kuo Y.W., Chang Y.L., Shih J.Y., Chen Y.H., Tsai M.F., et al. EML4-ALK translocation predicts better outcome in lung adenocarcinoma patients with wild-type EGFR. J Thorac Oncol 2012, 7:98-104.
-
(2012)
J Thorac Oncol
, vol.7
, pp. 98-104
-
-
Wu, S.G.1
Kuo, Y.W.2
Chang, Y.L.3
Shih, J.Y.4
Chen, Y.H.5
Tsai, M.F.6
-
19
-
-
79953029071
-
Anaplastic lymphoma kinase gene rearrangements in non-small cell lung cancer are associated with prolonged progression-free survival on pemetrexed
-
Camidge D.R., Kono S.A., Lu X., Okuyama S., Baron A.E., Oton A.B., et al. Anaplastic lymphoma kinase gene rearrangements in non-small cell lung cancer are associated with prolonged progression-free survival on pemetrexed. J Thorac Oncol 2011, 6:774-780.
-
(2011)
J Thorac Oncol
, vol.6
, pp. 774-780
-
-
Camidge, D.R.1
Kono, S.A.2
Lu, X.3
Okuyama, S.4
Baron, A.E.5
Oton, A.B.6
-
20
-
-
80052261903
-
Anaplastic lymphoma kinase translocation: a predictive biomarker of pemetrexed in patients with non-small cell lung cancer
-
Lee J.O., Kim T.M., Lee S.H., Kim D.W., Kim S., Jeon Y.K., et al. Anaplastic lymphoma kinase translocation: a predictive biomarker of pemetrexed in patients with non-small cell lung cancer. J Thorac Oncol 2011, 6:1474-1480.
-
(2011)
J Thorac Oncol
, vol.6
, pp. 1474-1480
-
-
Lee, J.O.1
Kim, T.M.2
Lee, S.H.3
Kim, D.W.4
Kim, S.5
Jeon, Y.K.6
-
21
-
-
84871040678
-
Favorable clinical outcomes of pemetrexed treatment in anaplastic lymphoma kinase positive non-small-cell lung cancer
-
Lee H.Y., Ahn H.K., Jeong J.Y., Kwon M.J., Han J.H., Sun J.M., et al. Favorable clinical outcomes of pemetrexed treatment in anaplastic lymphoma kinase positive non-small-cell lung cancer. Lung Cancer 2013, 79:40-45.
-
(2013)
Lung Cancer
, vol.79
, pp. 40-45
-
-
Lee, H.Y.1
Ahn, H.K.2
Jeong, J.Y.3
Kwon, M.J.4
Han, J.H.5
Sun, J.M.6
-
22
-
-
84865964696
-
Oncogene status predicts patterns of metastatic spread in treatment-naive nonsmall cell lung cancer
-
Doebele R.C., Lu X., Sumey C., Maxson D.A., Weickhardt A.J., Oton A.B., et al. Oncogene status predicts patterns of metastatic spread in treatment-naive nonsmall cell lung cancer. Cancer 2012, 118:4502-4511.
-
(2012)
Cancer
, vol.118
, pp. 4502-4511
-
-
Doebele, R.C.1
Lu, X.2
Sumey, C.3
Maxson, D.A.4
Weickhardt, A.J.5
Oton, A.B.6
-
23
-
-
34548462932
-
The IASLC lung cancer staging project: validation of the proposals for revision of the T, N, and M descriptors and consequent stage groupings in the forthcoming (seventh) edition of the TNM classification of malignant tumours
-
Groome P.A., Bolejack V., Crowley J.J., Kennedy C., Krasnik M., Sobin L.H., et al. The IASLC lung cancer staging project: validation of the proposals for revision of the T, N, and M descriptors and consequent stage groupings in the forthcoming (seventh) edition of the TNM classification of malignant tumours. J Thorac Oncol 2007, 2:694-705.
-
(2007)
J Thorac Oncol
, vol.2
, pp. 694-705
-
-
Groome, P.A.1
Bolejack, V.2
Crowley, J.J.3
Kennedy, C.4
Krasnik, M.5
Sobin, L.H.6
-
24
-
-
84884211534
-
Multiplexed gene expression and fusion transcript analysis to detect ALK fusions in lung cancer
-
Lira M.E., Kim T.M., Huang D., Deng S., Koh Y., Jang B., et al. Multiplexed gene expression and fusion transcript analysis to detect ALK fusions in lung cancer. J Mol Diagn 2013, 15:51-61.
-
(2013)
J Mol Diagn
, vol.15
, pp. 51-61
-
-
Lira, M.E.1
Kim, T.M.2
Huang, D.3
Deng, S.4
Koh, Y.5
Jang, B.6
-
25
-
-
84883022821
-
Clinical, pathological and biological features associated with BRAF mutations in non-small cell lung cancer
-
Cardarella S., Ogino A., Nishino M., Butaney M., Shen J., Lydon C., et al. Clinical, pathological and biological features associated with BRAF mutations in non-small cell lung cancer. Clin Cancer Res 2013, 19:4532-4540.
-
(2013)
Clin Cancer Res
, vol.19
, pp. 4532-4540
-
-
Cardarella, S.1
Ogino, A.2
Nishino, M.3
Butaney, M.4
Shen, J.5
Lydon, C.6
-
26
-
-
84863338079
-
ROS1 rearrangements define a unique molecular class of lung cancers
-
Bergethon K., Shaw A.T., Ou S.H., Katayama R., Lovly C.M., McDonald N.T., et al. ROS1 rearrangements define a unique molecular class of lung cancers. J Clin Oncol 2012, 30:863-870.
-
(2012)
J Clin Oncol
, vol.30
, pp. 863-870
-
-
Bergethon, K.1
Shaw, A.T.2
Ou, S.H.3
Katayama, R.4
Lovly, C.M.5
McDonald, N.T.6
-
27
-
-
84863230117
-
A transforming KIF5B and RET gene fusion in lung adenocarcinoma revealed from whole-genome and transcriptome sequencing
-
Ju Y.S., Lee W.C., Shin J.Y., Lee S., Bleazard T., Won J.K., et al. A transforming KIF5B and RET gene fusion in lung adenocarcinoma revealed from whole-genome and transcriptome sequencing. Genome Res 2012, 22:436-445.
-
(2012)
Genome Res
, vol.22
, pp. 436-445
-
-
Ju, Y.S.1
Lee, W.C.2
Shin, J.Y.3
Lee, S.4
Bleazard, T.5
Won, J.K.6
|