-
1
-
-
84864020054
-
Brentuximab vedotin and panobinostat: new drugs for Hodgkin's lymphoma - can they make one of medical oncology's chemotherapy success stories more successful?
-
Canellos G.P. Brentuximab vedotin and panobinostat: new drugs for Hodgkin's lymphoma - can they make one of medical oncology's chemotherapy success stories more successful?. J Clin Oncol 2012, 18:2171-2172.
-
(2012)
J Clin Oncol
, vol.18
, pp. 2171-2172
-
-
Canellos, G.P.1
-
2
-
-
0018822166
-
Curability of advanced Hodgkin's disease with chemotherapy: long-term follow-up of MOPP-treated patients at the National Cancer Institute
-
De Vita V.T., Simon R.M., Hubbard S.M. Curability of advanced Hodgkin's disease with chemotherapy: long-term follow-up of MOPP-treated patients at the National Cancer Institute. Ann Intern Med 1980, 92:587-595.
-
(1980)
Ann Intern Med
, vol.92
, pp. 587-595
-
-
De Vita, V.T.1
Simon, R.M.2
Hubbard, S.M.3
-
3
-
-
0020321019
-
ABVD chemotherapy in the treatment of Hodgkin's disease
-
Bonadonna G., Santoro A. ABVD chemotherapy in the treatment of Hodgkin's disease. Cancer Treat Rev 1982, 9:21-35.
-
(1982)
Cancer Treat Rev
, vol.9
, pp. 21-35
-
-
Bonadonna, G.1
Santoro, A.2
-
5
-
-
34748816127
-
Long-term results of autologous stem cell transplantation for primary refractory or relapsed Hodgkin's lymphoma
-
Majhail N.S., Weisdorf D.J., Defor T.E., et al. Long-term results of autologous stem cell transplantation for primary refractory or relapsed Hodgkin's lymphoma. Biol Blood Marrow Transplant 2006, 12:1065-1072.
-
(2006)
Biol Blood Marrow Transplant
, vol.12
, pp. 1065-1072
-
-
Majhail, N.S.1
Weisdorf, D.J.2
Defor, T.E.3
-
6
-
-
0028829967
-
CD30 (Ki-1) molecule: a new cytokine receptor of the tumor necrosis factor superfamily as a tool for diagnosis and immunotherapy
-
Falini B., Pileri S., Pizzolo G., et al. CD30 (Ki-1) molecule: a new cytokine receptor of the tumor necrosis factor superfamily as a tool for diagnosis and immunotherapy. Blood 1995, 85:1-14.
-
(1995)
Blood
, vol.85
, pp. 1-14
-
-
Falini, B.1
Pileri, S.2
Pizzolo, G.3
-
7
-
-
0032911899
-
CD 30 in normal and neoplastic cells
-
Chiarle R., Podda A., Prolla G., et al. CD 30 in normal and neoplastic cells. Clin Immunol 1999, 90:157-164.
-
(1999)
Clin Immunol
, vol.90
, pp. 157-164
-
-
Chiarle, R.1
Podda, A.2
Prolla, G.3
-
8
-
-
78851471130
-
The molecular pathogenesis of Hodgkin lymphoma
-
Farrel K., Jarret R.F. The molecular pathogenesis of Hodgkin lymphoma. Histopathology 2011, 58:15-25.
-
(2011)
Histopathology
, vol.58
, pp. 15-25
-
-
Farrel, K.1
Jarret, R.F.2
-
9
-
-
0036645267
-
The anti-CD30 monoclonal antibody SNG-30 promotes growth arrest and DNA fragmentation in vitro and affects antitumor activity in models of Hodgkin's disease
-
Walh A.F., Klussman K., Thompson J.D., et al. The anti-CD30 monoclonal antibody SNG-30 promotes growth arrest and DNA fragmentation in vitro and affects antitumor activity in models of Hodgkin's disease. Cancer Res 2012, 62:3736-3742.
-
(2012)
Cancer Res
, vol.62
, pp. 3736-3742
-
-
Walh, A.F.1
Klussman, K.2
Thompson, J.D.3
-
10
-
-
67649908324
-
A phase II study of SNG-30 (anti-CD30 mAb) in Hodgkin lymphoma or systemic anaplastic large cell lymphoma
-
Forero-Torres A., Leonard J.P., Younes A., et al. A phase II study of SNG-30 (anti-CD30 mAb) in Hodgkin lymphoma or systemic anaplastic large cell lymphoma. Br J Haematol 2009, 146:171-179.
-
(2009)
Br J Haematol
, vol.146
, pp. 171-179
-
-
Forero-Torres, A.1
Leonard, J.P.2
Younes, A.3
-
11
-
-
34447573999
-
Phase I/II study of an anti-CD30 monoclonal antibody (MDX-060) in Hodgkin's lymphoma and anaplastic large-cell lymphoma
-
Ansell S.M., Horwitz S.M., Engert A., et al. Phase I/II study of an anti-CD30 monoclonal antibody (MDX-060) in Hodgkin's lymphoma and anaplastic large-cell lymphoma. J Clin Oncol 2007, 25:2764-2769.
-
(2007)
J Clin Oncol
, vol.25
, pp. 2764-2769
-
-
Ansell, S.M.1
Horwitz, S.M.2
Engert, A.3
-
12
-
-
77958490178
-
Serious pulmonary toxicity in patients with Hodgkin's lymphoma with SGN-30, gemcitabine, vinorelbine, and liposomal doxorubicin is associated with an Fc-RIIIa-158 V/F polymorphism
-
Blum K.A., Jung S.H., Johnson J.L., et al. Serious pulmonary toxicity in patients with Hodgkin's lymphoma with SGN-30, gemcitabine, vinorelbine, and liposomal doxorubicin is associated with an Fc-RIIIa-158 V/F polymorphism. Ann Oncol 2010, 21:2246-2254.
-
(2010)
Ann Oncol
, vol.21
, pp. 2246-2254
-
-
Blum, K.A.1
Jung, S.H.2
Johnson, J.L.3
-
13
-
-
55249097877
-
Novel peptide linkers for highly potent antibody-auristatin conjugate
-
Doronina S.O., Bovee T.D., Meyer D.W., et al. Novel peptide linkers for highly potent antibody-auristatin conjugate. Bioconjug Chem 2008, 19:1960-1963.
-
(2008)
Bioconjug Chem
, vol.19
, pp. 1960-1963
-
-
Doronina, S.O.1
Bovee, T.D.2
Meyer, D.W.3
-
14
-
-
78650301478
-
Brentuximab vedotin: delivering an antimitotic drug to activated lymphoma cells
-
Ansell S.M. Brentuximab vedotin: delivering an antimitotic drug to activated lymphoma cells. Expert Opin Investig Drugs 2011, 20:99-105.
-
(2011)
Expert Opin Investig Drugs
, vol.20
, pp. 99-105
-
-
Ansell, S.M.1
-
15
-
-
44649184200
-
Combination of the anti-CD30-auristation-E antibody-drug conjugate (SNG-35) with chemotherapy improves antitumor activity in Hodgkin lymphoma
-
Oflazoglu E., Kissler K.M., Sievers E.L., et al. Combination of the anti-CD30-auristation-E antibody-drug conjugate (SNG-35) with chemotherapy improves antitumor activity in Hodgkin lymphoma. Br J Haematol 2008, 142:69-73.
-
(2008)
Br J Haematol
, vol.142
, pp. 69-73
-
-
Oflazoglu, E.1
Kissler, K.M.2
Sievers, E.L.3
-
16
-
-
78049515807
-
Brentuximab vedotin (SNG-35) for relapsed CD30 -positive lymphomas
-
Younes A., Barlett L., Leonard J.P., et al. Brentuximab vedotin (SNG-35) for relapsed CD30 -positive lymphomas. N Engl J Med 2010, 363:1812-1821.
-
(2010)
N Engl J Med
, vol.363
, pp. 1812-1821
-
-
Younes, A.1
Barlett, L.2
Leonard, J.P.3
-
17
-
-
84855465227
-
A phase I weekly dosing study of brentuximab vedotin in patients with relapsed/refractor CD 30-positive hematologic malignancies
-
Fanale M.A., Forero-Torres A., Rosenblatt J.D., et al. A phase I weekly dosing study of brentuximab vedotin in patients with relapsed/refractor CD 30-positive hematologic malignancies. Clin Cancer Res 2012, 18:248-255.
-
(2012)
Clin Cancer Res
, vol.18
, pp. 248-255
-
-
Fanale, M.A.1
Forero-Torres, A.2
Rosenblatt, J.D.3
-
18
-
-
84863676500
-
Results of a pivotal phase II study of brentuximab vedotin for patients with relapsed or refractory Hodgkin's lymphoma
-
Younes A., Gopal A.K., Smith S.E., et al. Results of a pivotal phase II study of brentuximab vedotin for patients with relapsed or refractory Hodgkin's lymphoma. J Clin Oncol 2012, 30:2183-2189.
-
(2012)
J Clin Oncol
, vol.30
, pp. 2183-2189
-
-
Younes, A.1
Gopal, A.K.2
Smith, S.E.3
-
19
-
-
52949122818
-
Neuropathy associated with microtubule inhibitors: diagnosis, incidence, and management
-
Swain S.M., Arezzo J.C. Neuropathy associated with microtubule inhibitors: diagnosis, incidence, and management. Clin Adv Hematol Oncol 2008, 6:455-467.
-
(2008)
Clin Adv Hematol Oncol
, vol.6
, pp. 455-467
-
-
Swain, S.M.1
Arezzo, J.C.2
-
20
-
-
84868561570
-
U.S. Food and Drug Administration approval summary: brentuximab vedotin for the treatment of relapsed Hodgkin lymphoma or relapsed systemic anaplastic large-cell lymphoma
-
De Claro A., McGinn K., Kwitkowski V., et al. U.S. Food and Drug Administration approval summary: brentuximab vedotin for the treatment of relapsed Hodgkin lymphoma or relapsed systemic anaplastic large-cell lymphoma. Clin Cancer Res 2012, 18:5845-5849.
-
(2012)
Clin Cancer Res
, vol.18
, pp. 5845-5849
-
-
De Claro, A.1
McGinn, K.2
Kwitkowski, V.3
-
21
-
-
0034283760
-
European Task Force on lymphoma Project on lymphocyte predominance Hodgkin disease: histologic and immunohistologic analysis of submitted cases reveals 2 types of Hodgkin disease with nodular growth pattern and abundant lymphocytes
-
Anagnostopoulos I., Hansmann M.L., Franssila K., et al. European Task Force on lymphoma Project on lymphocyte predominance Hodgkin disease: histologic and immunohistologic analysis of submitted cases reveals 2 types of Hodgkin disease with nodular growth pattern and abundant lymphocytes. Blood 2000, 96:1889-1899.
-
(2000)
Blood
, vol.96
, pp. 1889-1899
-
-
Anagnostopoulos, I.1
Hansmann, M.L.2
Franssila, K.3
-
22
-
-
77952574651
-
Allogenic transplantation improves the overall and progression-free survival of Hodgkin lymphoma patients relapsing after autologous transplantation: a retrospective study based on the time of HLA typing and donor availability
-
Sarina B., Castagna L., Farian L., et al. Allogenic transplantation improves the overall and progression-free survival of Hodgkin lymphoma patients relapsing after autologous transplantation: a retrospective study based on the time of HLA typing and donor availability. Blood 2010, 115:3671-3677.
-
(2010)
Blood
, vol.115
, pp. 3671-3677
-
-
Sarina, B.1
Castagna, L.2
Farian, L.3
-
23
-
-
84892848427
-
Brentuximab vedotin combined with donor lymphocyte infusions for early relapse of Hodgkin lymphoma after allogeneic stem-cell transplantation induces tumor-specific immunity and sustained clinical remission
-
[Epub ahead of print]
-
Theurich S., Malcher J., Wennhold K., et al. Brentuximab vedotin combined with donor lymphocyte infusions for early relapse of Hodgkin lymphoma after allogeneic stem-cell transplantation induces tumor-specific immunity and sustained clinical remission. J Clin Oncol 2012, [Epub ahead of print].
-
(2012)
J Clin Oncol
-
-
Theurich, S.1
Malcher, J.2
Wennhold, K.3
-
24
-
-
80052969289
-
Histology and time to progression predict survival for lymphoma recurring after reduced-intensity conditioning and allogenic hematopoietic cell transplantation
-
Ram R., Gooley T.A., Maloney D.G., et al. Histology and time to progression predict survival for lymphoma recurring after reduced-intensity conditioning and allogenic hematopoietic cell transplantation. Biol Blood Marrow Transplant 2011, 17:1537-1545.
-
(2011)
Biol Blood Marrow Transplant
, vol.17
, pp. 1537-1545
-
-
Ram, R.1
Gooley, T.A.2
Maloney, D.G.3
-
25
-
-
80052964964
-
Relapse of lymphoma after allogeneic hematopoietic cell transplantation: management strategies and outcome
-
Wudhikarn K., Brunstein C.G., Bachanova V., et al. Relapse of lymphoma after allogeneic hematopoietic cell transplantation: management strategies and outcome. Biol Blood Marrow Transplant 2011, 17:1497-1504.
-
(2011)
Biol Blood Marrow Transplant
, vol.17
, pp. 1497-1504
-
-
Wudhikarn, K.1
Brunstein, C.G.2
Bachanova, V.3
-
26
-
-
84864132475
-
Safety and efficacy of brentuximab vedotin for Hodgkin lymphoma recurring after allogenic stem cell transplantation
-
Gopal A.K., Ramchandren R., O'Connor O.A., et al. Safety and efficacy of brentuximab vedotin for Hodgkin lymphoma recurring after allogenic stem cell transplantation. Blood 2012, 120:560-568.
-
(2012)
Blood
, vol.120
, pp. 560-568
-
-
Gopal, A.K.1
Ramchandren, R.2
O'Connor, O.A.3
-
27
-
-
84875414323
-
Frontline therapy with brentuximab vedotin combined with ABVD or AVD in patients with newly diagnosed advanced stage Hodgkin lymphoma
-
Ansell S.M., Connors J.M., Park S.I., O'Meara M.M., Younes A. Frontline therapy with brentuximab vedotin combined with ABVD or AVD in patients with newly diagnosed advanced stage Hodgkin lymphoma. ASH Ann Meeting Abstr 2012, 120:798.
-
(2012)
ASH Ann Meeting Abstr
, vol.120
, pp. 798
-
-
Ansell, S.M.1
Connors, J.M.2
Park, S.I.3
O'Meara, M.M.4
Younes, A.5
-
28
-
-
84892836063
-
-
ClinicalTrials.gov.: a phase 3 study of brentuximab vedotin (SGN-35) in patients at high risk of residual Hodgkin lymphoma following stem cell transplant (the AETHERA trial). Accessed December 4,
-
ClinicalTrials.gov.: a phase 3 study of brentuximab vedotin (SGN-35) in patients at high risk of residual Hodgkin lymphoma following stem cell transplant (the AETHERA trial). Accessed December 4, 2012. http://www.clinicaltrials.gov/ct2/show/NCT01100502.
-
(2012)
-
-
-
29
-
-
84892880308
-
-
US Food and Drug Administration. FDA drug safety communication: new boxed warning and contraindication for Adcetris (brentuximab vedotin), January 13, 2012. Accessed December 10
-
US Food and Drug Administration. FDA drug safety communication: new boxed warning and contraindication for Adcetris (brentuximab vedotin), January 13, 2012. Accessed December 10, 2012. http://www.fda.gov/Drugs/DrugSafety/ucm287668.htm.
-
(2012)
-
-
-
30
-
-
2342621426
-
Metilación del ADN: un fenómeno epigenético de importancia médica
-
Rodríguez Dorantes M., Téllez N., Cerbón M.A., et al. Metilación del ADN: un fenómeno epigenético de importancia médica. Rev Invest Clin 2004, 56:56-71.
-
(2004)
Rev Invest Clin
, vol.56
, pp. 56-71
-
-
Rodríguez Dorantes, M.1
Téllez, N.2
Cerbón, M.A.3
-
31
-
-
78651378094
-
Histone deacetylase inhibitors in Hodgkin lymphoma
-
Buglio D., Younes A. Histone deacetylase inhibitors in Hodgkin lymphoma. Invest New Drugs 2012, 28(Suppl. 1):S21-S27.
-
(2012)
Invest New Drugs
, vol.28
, Issue.SUPPL. 1
-
-
Buglio, D.1
Younes, A.2
-
32
-
-
79959218179
-
Clinical development of panobinostat in classical Hodgkin's lymphoma
-
Oki Y., Copeland A., Younes A. Clinical development of panobinostat in classical Hodgkin's lymphoma. Expert Rev Hematol 2011, 4:245-252.
-
(2011)
Expert Rev Hematol
, vol.4
, pp. 245-252
-
-
Oki, Y.1
Copeland, A.2
Younes, A.3
-
33
-
-
79959280862
-
a and VEGF, and synergizes with everolimus in Hodgkin lymphoma cell lines
-
a and VEGF, and synergizes with everolimus in Hodgkin lymphoma cell lines. Blood ASH Ann Meet Abstr 2012, 116:2851.
-
(2012)
Blood ASH Ann Meet Abstr
, vol.116
, pp. 2851
-
-
Lemoine, M.1
Buglio, D.2
Jona, A.3
-
34
-
-
51649092609
-
Vorinostat inhibits STAT6-mediated YH2 cytokine and TARC production and induces cell death in Hodgkin lymphoma cell lines
-
Buglio D., Georgakis G.V., Hanabuchi S., et al. Vorinostat inhibits STAT6-mediated YH2 cytokine and TARC production and induces cell death in Hodgkin lymphoma cell lines. Blood 2008, 112:1424-1433.
-
(2008)
Blood
, vol.112
, pp. 1424-1433
-
-
Buglio, D.1
Georgakis, G.V.2
Hanabuchi, S.3
-
35
-
-
79959248347
-
The histone deacetylase inhibitor entinostat (SNDX-275) targets Hodgkin lymphoma through a dual mechanism of immune modulation and apoptosis induction
-
Jona A., Khaskhely N., Buglio D., et al. The histone deacetylase inhibitor entinostat (SNDX-275) targets Hodgkin lymphoma through a dual mechanism of immune modulation and apoptosis induction. Blood ASH Ann Meet Abstr 2010, 116:2850.
-
(2010)
Blood ASH Ann Meet Abstr
, vol.116
, pp. 2850
-
-
Jona, A.1
Khaskhely, N.2
Buglio, D.3
-
36
-
-
84859843443
-
Histone deacetylase inhibition restores cisplatin sensitivity of Hodgkin's lymphoma cells
-
Kewitz S., Bernig T., Staege M.S. Histone deacetylase inhibition restores cisplatin sensitivity of Hodgkin's lymphoma cells. Leuk Res 2012, 36:773-778.
-
(2012)
Leuk Res
, vol.36
, pp. 773-778
-
-
Kewitz, S.1
Bernig, T.2
Staege, M.S.3
-
37
-
-
51649092609
-
Vorinostat inhibits STAT6-mediated TH2 cytokine and TARC production and induces cell death in Hodgkin lymphoma cell lines
-
Buglio D., Georgakis G.V., Hanabuchi S., et al. Vorinostat inhibits STAT6-mediated TH2 cytokine and TARC production and induces cell death in Hodgkin lymphoma cell lines. Blood 2008, 112:1424-1433.
-
(2008)
Blood
, vol.112
, pp. 1424-1433
-
-
Buglio, D.1
Georgakis, G.V.2
Hanabuchi, S.3
-
38
-
-
84864024420
-
Panobinostat in patients with relapsed/refractory Hodgkin's lymphoma after autologous stem-cell transplantation: results of a phase II study
-
Younes A., Sureda A., Ben-Yehuda D., et al. Panobinostat in patients with relapsed/refractory Hodgkin's lymphoma after autologous stem-cell transplantation: results of a phase II study. J Clin Oncol 2012, 30:2197-2203.
-
(2012)
J Clin Oncol
, vol.30
, pp. 2197-2203
-
-
Younes, A.1
Sureda, A.2
Ben-Yehuda, D.3
-
39
-
-
84859827198
-
The pan-deacetylase inhibitor panobinostat induces cell death and synergizes with everolimus in Hodgkin lymphoma cell lines
-
Lemoine M., Derenzini E., Buglio D., et al. The pan-deacetylase inhibitor panobinostat induces cell death and synergizes with everolimus in Hodgkin lymphoma cell lines. Blood 2012, 119:4017-4025.
-
(2012)
Blood
, vol.119
, pp. 4017-4025
-
-
Lemoine, M.1
Derenzini, E.2
Buglio, D.3
-
40
-
-
84856115538
-
A phase 2 study of vorinostat for treatment of relapsed or refractory Hodgkin lymphoma: Southwest Oncology Group Study S0517
-
Kirschbaum M.H., Goldman B.H., Zain J.M., et al. A phase 2 study of vorinostat for treatment of relapsed or refractory Hodgkin lymphoma: Southwest Oncology Group Study S0517. Leuk Lymphoma 2012, 53:259-262.
-
(2012)
Leuk Lymphoma
, vol.53
, pp. 259-262
-
-
Kirschbaum, M.H.1
Goldman, B.H.2
Zain, J.M.3
-
41
-
-
82555187781
-
Mocetinostat for relapsed classical Hodgkin's lymphoma: an open-label, single-arm, phase 2 trial
-
Younes A., Oki Y., Bociek R.G., et al. Mocetinostat for relapsed classical Hodgkin's lymphoma: an open-label, single-arm, phase 2 trial. Lancet Oncol 2011, 12:1222-1228.
-
(2011)
Lancet Oncol
, vol.12
, pp. 1222-1228
-
-
Younes, A.1
Oki, Y.2
Bociek, R.G.3
-
42
-
-
80052840489
-
The histone deacetylase inhibitor entinostat (SNDX-275) induces apoptosis in Hodgkin lymphoma cells and synergizes with Bcl-2 family inhibitors
-
Jóna A., Khaskhely N., Buglio D., et al. The histone deacetylase inhibitor entinostat (SNDX-275) induces apoptosis in Hodgkin lymphoma cells and synergizes with Bcl-2 family inhibitors. Exp Hematol 2011, 39:1007-1017.
-
(2011)
Exp Hematol
, vol.39
, pp. 1007-1017
-
-
Jóna, A.1
Khaskhely, N.2
Buglio, D.3
-
43
-
-
79953833721
-
ENGAGE-501: phase 2 study investigating the role of epigenetic therapy with entinostat (SNDX-275) in relapsed and refractory Hodgkin's lymphoma (HL), interim results
-
Younes A., Hernandez F., Bociek R.G., et al. ENGAGE-501: phase 2 study investigating the role of epigenetic therapy with entinostat (SNDX-275) in relapsed and refractory Hodgkin's lymphoma (HL), interim results. Blood ASH Ann Meet Abstr 2010, 116:3959.
-
(2010)
Blood ASH Ann Meet Abstr
, vol.116
, pp. 3959
-
-
Younes, A.1
Hernandez, F.2
Bociek, R.G.3
-
44
-
-
38849098573
-
Bendamustine in non-Hodgkin lymphoma: the double-agent that came from the Cold War
-
Forero-Torres A., Saleh M.N. Bendamustine in non-Hodgkin lymphoma: the double-agent that came from the Cold War. Clin Lymphoma Myeloma 2007, 8(Suppl. 1):S13-S17.
-
(2007)
Clin Lymphoma Myeloma
, vol.8
, Issue.SUPPL. 1
-
-
Forero-Torres, A.1
Saleh, M.N.2
-
45
-
-
0034744322
-
Bendamustine monotherapy in advanced and refractory chronic lymphocytic leukemia
-
Kath R., Blumenstengel K., Fricke H.J., et al. Bendamustine monotherapy in advanced and refractory chronic lymphocytic leukemia. J Cancer Res Clin Oncol 2001, 127:48-54.
-
(2001)
J Cancer Res Clin Oncol
, vol.127
, pp. 48-54
-
-
Kath, R.1
Blumenstengel, K.2
Fricke, H.J.3
-
46
-
-
0024512573
-
Bendamustin as an alternative approach to treat malignant non-Hodgkin's lymphoma
-
Ruffert K., Jahn H., Syrbe G., et al. Bendamustin as an alternative approach to treat malignant non-Hodgkin's lymphoma. Z Klin Med 1989, 8:671-674.
-
(1989)
Z Klin Med
, vol.8
, pp. 671-674
-
-
Ruffert, K.1
Jahn, H.2
Syrbe, G.3
-
47
-
-
0032456477
-
New drugs in the treatment of Hodgkin's disease
-
Borchmann P., Schnell R., Dielh V., et al. New drugs in the treatment of Hodgkin's disease. Ann Oncol 1998, 9(Suppl. 5):S103-S108.
-
(1998)
Ann Oncol
, vol.9
, Issue.SUPPL. 5
-
-
Borchmann, P.1
Schnell, R.2
Dielh, V.3
-
48
-
-
33846944775
-
Risk-adapted combined radiotherapy and chemotherapy for Hodgkin's disease
-
Herold M., Keinert K., Anger G. Risk-adapted combined radiotherapy and chemotherapy for Hodgkin's disease. Onkologie 1992, 15:501-505.
-
(1992)
Onkologie
, vol.15
, pp. 501-505
-
-
Herold, M.1
Keinert, K.2
Anger, G.3
-
49
-
-
0036340122
-
Metabolism and mechanisms of action of bendamustine: rationales for combination therapies
-
Gandhi W. Metabolism and mechanisms of action of bendamustine: rationales for combination therapies. Sem Oncol 2002, 29:4-11.
-
(2002)
Sem Oncol
, vol.29
, pp. 4-11
-
-
Gandhi, W.1
-
50
-
-
84874763617
-
Phase II study of bendamustine in relapsed and refractory Hodgkin lymphoma
-
Moskowitz A.J., Hamlin P.A., Perales M.A., et al. Phase II study of bendamustine in relapsed and refractory Hodgkin lymphoma. J Clin Oncol 2012, 10.1200/JCO.2012.45.3308.
-
(2012)
J Clin Oncol
-
-
Moskowitz, A.J.1
Hamlin, P.A.2
Perales, M.A.3
-
51
-
-
84872275912
-
Efficacy and safety of bendamustine for the treatment of patients with recurring Hodgkin lymphoma
-
Corazzelli G., Angilli F., DÁrco A., et al. Efficacy and safety of bendamustine for the treatment of patients with recurring Hodgkin lymphoma. Br J Haematol 2012, 10.1111/bjh.12120.
-
(2012)
Br J Haematol
-
-
Corazzelli, G.1
Angilli, F.2
Dárco, A.3
-
52
-
-
84892877901
-
Bendamustine for relapsed/refractory classical Hodgkin lymphoma after high dose chemotherapy and/or allogeneic transplant: a study of Fondazione Italiana Linfomi (FIL)
-
Anastasia A., Carlo-Stella C., Corradini P., et al. Bendamustine for relapsed/refractory classical Hodgkin lymphoma after high dose chemotherapy and/or allogeneic transplant: a study of Fondazione Italiana Linfomi (FIL). Blood ASH Ann Meeting 2012, 120:3652.
-
(2012)
Blood ASH Ann Meeting
, vol.120
, pp. 3652
-
-
Anastasia, A.1
Carlo-Stella, C.2
Corradini, P.3
-
53
-
-
84892855227
-
Mechanism of action: the unique pattern of bendamustine-induced cytotoxicity
-
Leoni L.M., Hartely J.A. Mechanism of action: the unique pattern of bendamustine-induced cytotoxicity. Sem Hematol 2001, 48(Suppl. 1):S1-S23.
-
(2001)
Sem Hematol
, vol.48
, Issue.SUPPL. 1
-
-
Leoni, L.M.1
Hartely, J.A.2
-
54
-
-
77953534075
-
The classical Hodgkin's lymphoma microenvironment and its role in promoting tumour growth and immune escape
-
Aldinucci D., Gloghini A., Pinto A., et al. The classical Hodgkin's lymphoma microenvironment and its role in promoting tumour growth and immune escape. J Pathol 2010, 221:248-263.
-
(2010)
J Pathol
, vol.221
, pp. 248-263
-
-
Aldinucci, D.1
Gloghini, A.2
Pinto, A.3
-
55
-
-
79955877897
-
Molecular pathogenesis of Hodgkin's lymphoma: increasing evidence of the importance of the microenvironment
-
Steidl C., Connors J.M., Gayscoyne R.D. Molecular pathogenesis of Hodgkin's lymphoma: increasing evidence of the importance of the microenvironment. J Clin Oncol 2011, 29:1812-1826.
-
(2011)
J Clin Oncol
, vol.29
, pp. 1812-1826
-
-
Steidl, C.1
Connors, J.M.2
Gayscoyne, R.D.3
-
56
-
-
81055123994
-
A phase 2 multicenter study of lenalidomide in relapsed or refractory classical Hodgkin lymphoma
-
Fehniger T.A., Larson S., Trinkaus K., et al. A phase 2 multicenter study of lenalidomide in relapsed or refractory classical Hodgkin lymphoma. Blood 2011, 118:5119-5125.
-
(2011)
Blood
, vol.118
, pp. 5119-5125
-
-
Fehniger, T.A.1
Larson, S.2
Trinkaus, K.3
-
57
-
-
69949096727
-
Mechanism of action of lenalidomide in hematological malignancies
-
Kotla V., Goel S., Nischal S., et al. Mechanism of action of lenalidomide in hematological malignancies. J Hematol Oncol 2009, 2(36):36.
-
(2009)
J Hematol Oncol
, vol.2
, Issue.36
, pp. 36
-
-
Kotla, V.1
Goel, S.2
Nischal, S.3
-
58
-
-
77949345555
-
Tumor-associated macrophages and survival in classic Hodgkin's lymphoma
-
Steidl C., Lee T., Shah S.P., et al. Tumor-associated macrophages and survival in classic Hodgkin's lymphoma. N Engl J Med 2010, 362:875-885.
-
(2010)
N Engl J Med
, vol.362
, pp. 875-885
-
-
Steidl, C.1
Lee, T.2
Shah, S.P.3
-
59
-
-
0036839013
-
Immunomodulatory drug CC-5013 overcomes drug resistance and is well tolerated in patients with relapsed multiple myeloma
-
Richardson P.G., Schlossman R.L., Weller E., et al. Immunomodulatory drug CC-5013 overcomes drug resistance and is well tolerated in patients with relapsed multiple myeloma. Blood 2002, 100:3063-3067.
-
(2002)
Blood
, vol.100
, pp. 3063-3067
-
-
Richardson, P.G.1
Schlossman, R.L.2
Weller, E.3
-
60
-
-
38949152337
-
Serum chemokine levels in Hodgkin lymphoma patients: highly increased levels of CCL17 and CCL22
-
Niens M., Visser L., Nolte I.M., et al. Serum chemokine levels in Hodgkin lymphoma patients: highly increased levels of CCL17 and CCL22. Br J Haematol 2008, 140:527-536.
-
(2008)
Br J Haematol
, vol.140
, pp. 527-536
-
-
Niens, M.1
Visser, L.2
Nolte, I.M.3
-
61
-
-
21344435055
-
Elevated serum levels of CC thymus and activation-related chemokine (TARC) in primary Hodgkin's disease: potential for a prognostic factor
-
Weihrauch M.R., Manzke O., Beyer M., et al. Elevated serum levels of CC thymus and activation-related chemokine (TARC) in primary Hodgkin's disease: potential for a prognostic factor. Cancer Res 2005, 65:5516-5519.
-
(2005)
Cancer Res
, vol.65
, pp. 5516-5519
-
-
Weihrauch, M.R.1
Manzke, O.2
Beyer, M.3
-
62
-
-
74049139971
-
Tumor flare reactions and response to lenalidomide in patients with refractory classic Hodgkin lymphoma
-
Corazzelli G., De Filippi R., Capobianco G., et al. Tumor flare reactions and response to lenalidomide in patients with refractory classic Hodgkin lymphoma. Am J Hematol 2010, 85:87-90.
-
(2010)
Am J Hematol
, vol.85
, pp. 87-90
-
-
Corazzelli, G.1
De Filippi, R.2
Capobianco, G.3
-
63
-
-
74049104854
-
Lenalidomide in patients with refractory or multiple relapsed Hodgkin lymphoma
-
Böll B., Borchmann P., Topp M.S., et al. Lenalidomide in patients with refractory or multiple relapsed Hodgkin lymphoma. Br J Haematol 2010, 148:480-482.
-
(2010)
Br J Haematol
, vol.148
, pp. 480-482
-
-
Böll, B.1
Borchmann, P.2
Topp, M.S.3
-
64
-
-
77952706603
-
Lenalidomide induced good clinical response in a patient with multiple relapsed and refractory Hodgkin's lymphoma
-
Mandac I., Kolonic S.O. Lenalidomide induced good clinical response in a patient with multiple relapsed and refractory Hodgkin's lymphoma. J Hematol Oncol 2010, 10.1186/1756-8722-3-20.
-
(2010)
J Hematol Oncol
-
-
Mandac, I.1
Kolonic, S.O.2
-
65
-
-
77951559617
-
A phase II trial of the oral mTOR inhibitor everolimus in relapsed Hodgkin lymphoma
-
Johnston P.B., Inwards D.J., Colgan J.P., et al. A phase II trial of the oral mTOR inhibitor everolimus in relapsed Hodgkin lymphoma. Am J Hematol 2010, 85:320-324.
-
(2010)
Am J Hematol
, vol.85
, pp. 320-324
-
-
Johnston, P.B.1
Inwards, D.J.2
Colgan, J.P.3
-
66
-
-
84870487839
-
Open-label, single-arm, Phase II study of everolimus in patients with relapsed/refractory classical Hodgkin lymphoma
-
Johnston P.B., Pinter-Brown L., Rogerio J., et al. Open-label, single-arm, Phase II study of everolimus in patients with relapsed/refractory classical Hodgkin lymphoma. Blood ASH Ann Meet Abstr 2011, 118:2717.
-
(2011)
Blood ASH Ann Meet Abstr
, vol.118
, pp. 2717
-
-
Johnston, P.B.1
Pinter-Brown, L.2
Rogerio, J.3
-
68
-
-
84892862528
-
Preclinical rationale for the use of the combined treatment with the AKT inhibitor perifosine and the multikinase inhibitor sorafenib in Hodgkin lymphoma
-
Locatelli S., Giacomini A., Guidetti A., et al. Preclinical rationale for the use of the combined treatment with the AKT inhibitor perifosine and the multikinase inhibitor sorafenib in Hodgkin lymphoma. Blood ASH Ann Meet Abstr 2011, 118:1653.
-
(2011)
Blood ASH Ann Meet Abstr
, vol.118
, pp. 1653
-
-
Locatelli, S.1
Giacomini, A.2
Guidetti, A.3
-
69
-
-
76949083372
-
Lestaurtinib, a multitargeted tyrosine kinase inhibitor: from bench to bedside
-
Shabbir M., Stuart R. Lestaurtinib, a multitargeted tyrosine kinase inhibitor: from bench to bedside. Expert Opin Investig Drugs 2010, 19:427-436.
-
(2010)
Expert Opin Investig Drugs
, vol.19
, pp. 427-436
-
-
Shabbir, M.1
Stuart, R.2
-
70
-
-
47049098437
-
Lestaurtinib (CEP701) is a JAK2 inhibitor that suppresses JAK2/STAT5 signaling and the proliferation of primary erythroid cells from patients with myeloproliferative disorders
-
Hexner E.O., Serdikoff C., Jan M., et al. Lestaurtinib (CEP701) is a JAK2 inhibitor that suppresses JAK2/STAT5 signaling and the proliferation of primary erythroid cells from patients with myeloproliferative disorders. Blood 2008, 111:5663-5671.
-
(2008)
Blood
, vol.111
, pp. 5663-5671
-
-
Hexner, E.O.1
Serdikoff, C.2
Jan, M.3
-
71
-
-
79955394571
-
Lestaurtinib inhibition of the JAK/STAT signaling pathway in Hodgkin lymphoma inhibits proliferation and induces apoptosis
-
Díaz T., Navarro A., Ferrer G., et al. Lestaurtinib inhibition of the JAK/STAT signaling pathway in Hodgkin lymphoma inhibits proliferation and induces apoptosis. PLoS One 2011, http://dx.doi.org/10.1371/journal.pone.0018856.
-
(2011)
PLoS One
-
-
Díaz, T.1
Navarro, A.2
Ferrer, G.3
-
72
-
-
80053992122
-
BAY 43-9006/sorafenib blocks CSF1R activity and induces apoptosis in various classical Hodgkin lymphoma cell lines
-
Sun S.M., Dijkstra M.K., Bijkerk A.C., et al. BAY 43-9006/sorafenib blocks CSF1R activity and induces apoptosis in various classical Hodgkin lymphoma cell lines. Br J Haematol 2011, 155:395-408.
-
(2011)
Br J Haematol
, vol.155
, pp. 395-408
-
-
Sun, S.M.1
Dijkstra, M.K.2
Bijkerk, A.C.3
-
73
-
-
84892886612
-
The future of proteasome inhibitors in the relapsed/refractory multiple mieloma
-
Orlowski R.Z. The future of proteasome inhibitors in the relapsed/refractory multiple mieloma. Oncology 2011, 25:1-16.
-
(2011)
Oncology
, vol.25
, pp. 1-16
-
-
Orlowski, R.Z.1
-
74
-
-
32644450349
-
Experience with bortezomib for the treatment of patients with relapsed classical Hodgkin lymphoma
-
Younes A., Pro B., Fayad L. Experience with bortezomib for the treatment of patients with relapsed classical Hodgkin lymphoma. Blood 2006, 107:1731-1732.
-
(2006)
Blood
, vol.107
, pp. 1731-1732
-
-
Younes, A.1
Pro, B.2
Fayad, L.3
-
75
-
-
34447566086
-
Single bortezomib in the treatment of relapsed and refractory Hodgkin lymphoma: Cancer and Leukemia Group B protocol 50206
-
Blum K.A., Johnson J.L., Niedzwieck D., et al. Single bortezomib in the treatment of relapsed and refractory Hodgkin lymphoma: Cancer and Leukemia Group B protocol 50206. Leuk Lymphoma 2007, 48:1313-1319.
-
(2007)
Leuk Lymphoma
, vol.48
, pp. 1313-1319
-
-
Blum, K.A.1
Johnson, J.L.2
Niedzwieck, D.3
|