-
1
-
-
33847065486
-
The Epigenomics of Cancer
-
DOI 10.1016/j.cell.2007.01.029, PII S0092867407001274
-
PA Jones SB Baylin 2007 The epigenomics of cancer Cell 128 683 692 1:CAS:528:DC%2BD2sXis12ju7k%3D 10.1016/j.cell.2007.01.029 17320506 (Pubitemid 46273572)
-
(2007)
Cell
, vol.128
, Issue.4
, pp. 683-692
-
-
Jones, P.A.1
Baylin, S.B.2
-
2
-
-
34250213859
-
DNA methylation as a therapeutic target in cancer
-
DOI 10.1158/1078-0432.CCR-06-2076
-
JP Issa 2007 DNA methylation as a therapeutic target in cancer Clin Cancer Res 13 1634 1637 1:CAS:528:DC%2BD2sXivV2gtr8%3D 10.1158/1078-0432.CCR-06- 2076 17363514 (Pubitemid 46952927)
-
(2007)
Clinical Cancer Research
, vol.13
, Issue.6
, pp. 1634-1637
-
-
Issa, J.-P.J.1
-
3
-
-
34547897023
-
Histone deacetylases and cancer
-
DOI 10.1038/sj.onc.1210610, PII 1210610
-
MA Glozak E Seto 2007 Histone deacetylases and cancer Oncogene 26 5420 5432 1:CAS:528:DC%2BD2sXovFeku7Y%3D 10.1038/sj.onc.1210610 17694083 (Pubitemid 47255924)
-
(2007)
Oncogene
, vol.26
, Issue.37
, pp. 5420-5432
-
-
Glozak, M.A.1
Seto, E.2
-
4
-
-
31344466008
-
DNA methylation and gene silencing in cancer
-
DOI 10.1038/ncponc0354, PII N0354
-
SB Baylin 2005 DNA methylation and gene silencing in cancer Nat Clin Pract Oncol 2 Suppl 1 S4 S11 1:CAS:528:DC%2BD28Xjs1Gisg%3D%3D 10.1038/ncponc0354 16341240 (Pubitemid 43135229)
-
(2005)
Nature Clinical Practice Oncology
, vol.2
, Issue.SUPPL. 1
-
-
Baylin, S.B.1
-
5
-
-
49249116407
-
A work in progress: The clinical development of histone deacetylase inhibitors
-
10.4161/epi.3.3.6253 18487953
-
S Marsoni G Damia G Camboni 2008 A work in progress: the clinical development of histone deacetylase inhibitors Epigenetics 3 164 171 10.4161/epi.3.3.6253 18487953
-
(2008)
Epigenetics
, vol.3
, pp. 164-171
-
-
Marsoni, S.1
Damia, G.2
Camboni, G.3
-
6
-
-
33644873930
-
Histone deacetylase inhibitors reduce VEGF production and induce growth suppression and apoptosis in human mantle cell lymphoma
-
1:CAS:528:DC%2BD28XitFSlt7c%3D 10.1111/j.1600-0609.2005.00546.x 16343270
-
U Heider M Kaiser J Sterz, et al. 2006 Histone deacetylase inhibitors reduce VEGF production and induce growth suppression and apoptosis in human mantle cell lymphoma Eur J Haematol 76 42 50 1:CAS:528:DC%2BD28XitFSlt7c%3D 10.1111/j.1600-0609.2005.00546.x 16343270
-
(2006)
Eur J Haematol
, vol.76
, pp. 42-50
-
-
Heider, U.1
Kaiser, M.2
Sterz, J.3
-
7
-
-
33747836834
-
Activation of mitochondrial pathway is crucial for tumor selective induction of apoptosis by LAQ824
-
1:CAS:528:DC%2BD28Xht12ht7rI 10.4161/cc.5.15.3099 16861932
-
S Wang Y Yan-Neale R Cai I Alimov D Cohen 2006 Activation of mitochondrial pathway is crucial for tumor selective induction of apoptosis by LAQ824 Cell Cycle 5 1662 1668 1:CAS:528:DC%2BD28Xht12ht7rI 10.4161/cc.5.15.3099 16861932
-
(2006)
Cell Cycle
, vol.5
, pp. 1662-1668
-
-
Wang, S.1
Yan-Neale, Y.2
Cai, R.3
Alimov, I.4
Cohen, D.5
-
8
-
-
33846876336
-
Histone deacetylase activities are required for innate immune cell control of Th1 but not Th2 effector cell function
-
DOI 10.1182/blood-2006-04-019711
-
JL Brogdon Y Xu SJ Szabo, et al. 2007 Histone deacetylase activities are required for innate immune cell control of Th1 but not Th2 effector cell function Blood 109 1123 1130 1:CAS:528:DC%2BD2sXjtFert7Y%3D 10.1182/blood-2006- 04-019711 17008546 (Pubitemid 46220659)
-
(2007)
Blood
, vol.109
, Issue.3
, pp. 1123-1130
-
-
Brogdon, J.L.1
Xu, Y.2
Szabo, S.J.3
An, S.4
Buxton, F.5
Cohen, D.6
Huang, Q.7
-
9
-
-
33748451151
-
Anticancer activities of histone deacetylase inhibitors
-
DOI 10.1038/nrd2133, PII NRD2133
-
JE Bolden MJ Peart RW Johnstone 2006 Anticancer activities of histone deacetylase inhibitors Nat Rev Drug Discov 5 769 784 1:CAS:528: DC%2BD28XptVCltrY%3D 10.1038/nrd2133 16955068 (Pubitemid 44348499)
-
(2006)
Nature Reviews Drug Discovery
, vol.5
, Issue.9
, pp. 769-784
-
-
Bolden, J.E.1
Peart, M.J.2
Johnstone, R.W.3
-
10
-
-
30344477367
-
Histone deacetylase inhibitors and the promise of epigenetic (and more) treatments for cancer
-
DOI 10.1038/nrc1779
-
S Minucci PG Pelicci 2006 Histone deacetylase inhibitors and the promise of epigenetic (and more) treatments for cancer Nat Rev Cancer 6 38 51 1:CAS:528:DC%2BD28Xht1GgsA%3D%3D 10.1038/nrc1779 16397526 (Pubitemid 43054973)
-
(2006)
Nature Reviews Cancer
, vol.6
, Issue.1
, pp. 38-51
-
-
Minucci, S.1
Pelicci, P.G.2
-
11
-
-
28044471827
-
Acetylation and deacetylation of non-histone proteins
-
DOI 10.1016/j.gene.2005.09.010, PII S037811190500572X
-
MA Glozak N Sengupta X Zhang E Seto 2005 Acetylation and deacetylation of non-histone proteins Gene 363 15 23 1:CAS:528:DC%2BD2MXht1Klu7%2FN 10.1016/j.gene.2005.09.010 16289629 (Pubitemid 41691888)
-
(2005)
Gene
, vol.363
, Issue.1-2
, pp. 15-23
-
-
Glozak, M.A.1
Sengupta, N.2
Zhang, X.3
Seto, E.4
-
12
-
-
67449127083
-
Cytotoxicity mediated by histone deacetylase inhibitors in cancer cells: Mechanisms and potential clinical implications
-
1:CAS:528:DC%2BD1MXntlOis74%3D 10.1158/1078-0432.CCR-08-2787 19509170
-
DS Schrump 2009 Cytotoxicity mediated by histone deacetylase inhibitors in cancer cells: mechanisms and potential clinical implications Clin Cancer Res 15 3947 3957 1:CAS:528:DC%2BD1MXntlOis74%3D 10.1158/1078-0432.CCR-08-2787 19509170
-
(2009)
Clin Cancer Res
, vol.15
, pp. 3947-3957
-
-
Schrump, D.S.1
-
13
-
-
69449093587
-
HDAC inhibitor-based therapies and haematological malignancy
-
1:STN:280:DC%2BD1MrjtlOkuw%3D%3D 10.1093/annonc/mdn792 19515748
-
L Stimson V Wood O Khan S Fotheringham NB La Thangue 2009 HDAC inhibitor-based therapies and haematological malignancy Ann Oncol 20 1293 1302 1:STN:280:DC%2BD1MrjtlOkuw%3D%3D 10.1093/annonc/mdn792 19515748
-
(2009)
Ann Oncol
, vol.20
, pp. 1293-1302
-
-
Stimson, L.1
Wood, V.2
Khan, O.3
Fotheringham, S.4
La Thangue, N.B.5
-
14
-
-
33845996135
-
Phase 2 trial of oral vorinostat (suberoylanilide hydroxamic acid, SAHA) for refractory cutaneous T-cell lymphoma (CTCL)
-
DOI 10.1182/blood-2006-06-025999
-
M Duvic R Talpur X Ni, et al. 2007 Phase 2 trial of oral vorinostat (suberoylanilide hydroxamic acid, SAHA) for refractory cutaneous T-cell lymphoma (CTCL) Blood 109 31 39 1:CAS:528:DC%2BD2sXivVyrt7g%3D 10.1182/blood-2006-06- 025999 16960145 (Pubitemid 46053039)
-
(2007)
Blood
, vol.109
, Issue.1
, pp. 31-39
-
-
Duvic, M.1
Talpur, R.2
Ni, X.3
Zhang, C.4
Hazarika, P.5
Kelly, C.6
Chiao, J.H.7
Reilly, J.F.8
Ricker, J.L.9
Richon, V.M.10
Frankel, S.R.11
-
15
-
-
73949149251
-
Phase II multi-institutional trial of the histone deacetylase inhibitor romidepsin as monotherapy for patients with cutaneous T-cell lymphoma
-
1:CAS:528:DC%2BD1MXhsFKkt7vO 10.1200/JCO.2008.21.6150 19826128
-
RL Piekarz R Frye M Turner, et al. 2009 Phase II multi-institutional trial of the histone deacetylase inhibitor romidepsin as monotherapy for patients with cutaneous T-cell lymphoma J Clin Oncol 27 5410 5417 1:CAS:528:DC%2BD1MXhsFKkt7vO 10.1200/JCO.2008.21.6150 19826128
-
(2009)
J Clin Oncol
, vol.27
, pp. 5410-5417
-
-
Piekarz, R.L.1
Frye, R.2
Turner, M.3
-
16
-
-
37849019672
-
Determination of the class and isoform selectivity of small-molecule histone deacetylase inhibitors
-
DOI 10.1042/BJ20070779
-
N Khan M Jeffers S Kumar, et al. 2008 Determination of the class and isoform selectivity of small-molecule histone deacetylase inhibitors Biochem J 409 581 589 1:CAS:528:DC%2BD1cXhtlSru7o%3D 10.1042/BJ20070779 17868033 (Pubitemid 351184977)
-
(2008)
Biochemical Journal
, vol.409
, Issue.2
, pp. 581-589
-
-
Khan, N.1
Jeffers, M.2
Kumar, S.3
Hackett, C.4
Boldog, F.5
Khramtsov, N.6
Qian, X.7
Mills, E.8
Berghs, S.C.9
Carey, N.10
Finn, P.W.11
Collins, L.S.12
Tumber, A.13
Ritchie, J.W.14
Jensen, P.B.15
Lichenstein, H.S.16
Sehested, M.17
-
17
-
-
34248649731
-
The molecular mechanism of HDAC inhibitors in anticancer effects
-
1:CAS:528:DC%2BD28XhtFOnurjO 16978537
-
G Bi G Jiang 2006 The molecular mechanism of HDAC inhibitors in anticancer effects Cell Mol Immunol 3 285 290 1:CAS:528:DC%2BD28XhtFOnurjO 16978537
-
(2006)
Cell Mol Immunol
, vol.3
, pp. 285-290
-
-
Bi, G.1
Jiang, G.2
-
18
-
-
78649304686
-
Role of histone deacetylases and their inhibitors in cancer biology and treatment
-
Beumer JH, Tawbi H (2010) Role of histone deacetylases and their inhibitors in cancer biology and treatment. Curr Clin Pharmacol 5(3):196-208
-
(2010)
Curr Clin Pharmacol
, vol.5
, Issue.3
, pp. 196-208
-
-
Beumer, J.H.1
Tawbi, H.2
-
19
-
-
73949128107
-
Histone deacetylase inhibitors in cancer therapy
-
1:CAS:528:DC%2BD1MXhsFKkt7vE 10.1200/JCO.2009.22.1291 19826124
-
AA Lane BA Chabner 2009 Histone deacetylase inhibitors in cancer therapy J Clin Oncol 27 5459 5468 1:CAS:528:DC%2BD1MXhsFKkt7vE 10.1200/JCO.2009.22.1291 19826124
-
(2009)
J Clin Oncol
, vol.27
, pp. 5459-5468
-
-
Lane, A.A.1
Chabner, B.A.2
-
20
-
-
73849114072
-
Histone deacetylase inhibitors induce thyroid cancer-specific apoptosis through proteasome-dependent inhibition of TRAIL degradation
-
Borbone E, Berlingieri MT, De Bellis F et al (2010) Histone deacetylase inhibitors induce thyroid cancer-specific apoptosis through proteasome-dependent inhibition of TRAIL degradation. Oncogene 29:105-116
-
(2010)
Oncogene
, vol.29
, pp. 105-116
-
-
Borbone, E.1
Berlingieri, M.T.2
De Bellis, F.3
-
21
-
-
67449127082
-
Clinical studies of histone deacetylase inhibitors
-
1:CAS:528:DC%2BD1MXntlOis78%3D 10.1158/1078-0432.CCR-08-2785 19509172
-
HM Prince MJ Bishton SJ Harrison 2009 Clinical studies of histone deacetylase inhibitors Clin Cancer Res 15 3958 3969 1:CAS:528: DC%2BD1MXntlOis78%3D 10.1158/1078-0432.CCR-08-2785 19509172
-
(2009)
Clin Cancer Res
, vol.15
, pp. 3958-3969
-
-
Prince, H.M.1
Bishton, M.J.2
Harrison, S.J.3
-
22
-
-
67650090545
-
Histone deacetylase inhibitors: Potential in cancer therapy
-
1:CAS:528:DC%2BD1MXosFOiurg%3D 10.1002/jcb.22185 19459166
-
PA Marks WS Xu 2009 Histone deacetylase inhibitors: potential in cancer therapy J Cell Biochem 107 600 608 1:CAS:528:DC%2BD1MXosFOiurg%3D 10.1002/jcb.22185 19459166
-
(2009)
J Cell Biochem
, vol.107
, pp. 600-608
-
-
Marks, P.A.1
Xu, W.S.2
-
23
-
-
33644836549
-
Clinical experience with intravenous and oral formulations of the novel histone deacetylase inhibitor suberoylanilide hydroxamic acid in patients with advanced hematologic malignancies
-
DOI 10.1200/JCO.2005.01.9679
-
OA O'Connor ML Heaney L Schwartz, et al. 2006 Clinical experience with intravenous and oral formulations of the novel histone deacetylase inhibitor suberoylanilide hydroxamic acid in patients with advanced hematologic malignancies J Clin Oncol 24 166 173 10.1200/JCO.2005.01.9679 16330674 (Pubitemid 46630509)
-
(2006)
Journal of Clinical Oncology
, vol.24
, Issue.1
, pp. 166-173
-
-
O'Connor, O.A.1
Heaney, M.L.2
Schwartz, L.3
Richardson, S.4
Willim, R.5
MacGregor-Cortelli, B.6
Curly, T.7
Moskowitz, C.8
Portlock, C.9
Horwitz, S.10
Zelenetz, A.D.11
Frankel, S.12
Richon, V.13
Marks, P.14
Kelly, W.K.15
-
24
-
-
68449091357
-
Vorinostat (suberoylanilide hydroxamic acid) in relapsed or refractory hodgkin lymphoma: SWOG 0517
-
MH Kirschbaum BH Goldman JM Zain, et al. 2007 Vorinostat (suberoylanilide hydroxamic acid) in relapsed or refractory hodgkin lymphoma: SWOG 0517 Blood (ASH Annual Meeting Abstracts) 110 2574
-
(2007)
Blood (ASH Annual Meeting Abstracts)
, vol.110
, pp. 2574
-
-
Kirschbaum, M.H.1
Goldman, B.H.2
Zain, J.M.3
-
25
-
-
45249087817
-
A phase 2 study of vorinostat (suberoylanilide hydroxamic acid, SAHA) in relapsed or refractory indolent Non Hodgkin Lymphoma. A California Cancer Consortium Study
-
MH Kirschbaum JM Zain L Popplewell, et al. 2007 A phase 2 study of vorinostat (suberoylanilide hydroxamic acid, SAHA) in relapsed or refractory indolent Non Hodgkin Lymphoma. A California Cancer Consortium Study Blood (ASH Annual Meeting Abstracts) 110 2568
-
(2007)
Blood (ASH Annual Meeting Abstracts)
, vol.110
, pp. 2568
-
-
Kirschbaum, M.H.1
Zain, J.M.2
Popplewell, L.3
-
26
-
-
45249087368
-
Isotype-selective HDAC inhibitor MGCD0103 decreases serum TARC concentrations and produces clinical responses in heavily pretreated patients with relapsed classical Hodgkin Lymphoma (HL)
-
A Younes B Pro M Fanale, et al. 2007 Isotype-selective HDAC inhibitor MGCD0103 decreases serum TARC concentrations and produces clinical responses in heavily pretreated patients with relapsed classical Hodgkin Lymphoma (HL) Blood (ASH Annual Meeting Abstracts) 110 2566
-
(2007)
Blood (ASH Annual Meeting Abstracts)
, vol.110
, pp. 2566
-
-
Younes, A.1
Pro, B.2
Fanale, M.3
-
27
-
-
45249105006
-
Treatment of relapsed or refractory lymphoma with the oral isotype-selective histone deacetylase inhibitor MGCD0103: Interim results from a phase II study
-
A Younes A Wedgwood P McLaughlin, et al. 2007 Treatment of relapsed or refractory lymphoma with the oral isotype-selective histone deacetylase inhibitor MGCD0103: interim results from a phase II study Blood (ASH Annual Meeting Abstracts) 110 2571
-
(2007)
Blood (ASH Annual Meeting Abstracts)
, vol.110
, pp. 2571
-
-
Younes, A.1
Wedgwood, A.2
McLaughlin, P.3
-
28
-
-
77949463615
-
Novel treatment strategies for patients with relapsed classical Hodgkin lymphoma
-
Younes A (2009) Novel treatment strategies for patients with relapsed classical Hodgkin lymphoma. Hematology 2009:507-519
-
(2009)
Hematology
, vol.2009
, pp. 507-519
-
-
Younes, A.1
-
29
-
-
70349194470
-
Preliminary evidence of disease response to the pan deacetylase inhibitor panobinostat (LBH589) in refractory Hodgkin Lymphoma
-
1:CAS:528:DC%2BD1MXhtlWltbbF 10.1111/j.1365-2141.2009.07837.x 19663825
-
M Dickinson D Ritchie DJ DeAngelo, et al. 2009 Preliminary evidence of disease response to the pan deacetylase inhibitor panobinostat (LBH589) in refractory Hodgkin Lymphoma Br J Haematol 147 97 101 1:CAS:528: DC%2BD1MXhtlWltbbF 10.1111/j.1365-2141.2009.07837.x 19663825
-
(2009)
Br J Haematol
, vol.147
, pp. 97-101
-
-
Dickinson, M.1
Ritchie, D.2
Deangelo, D.J.3
-
30
-
-
0037441887
-
Loss of the B-lineage-specific gene expression program in Hodgkin and Reed-Sternberg cells of Hodgkin lymphoma
-
DOI 10.1182/blood-2002-03-0839
-
I Schwering A Brauninger U Klein, et al. 2003 Loss of the B-lineage-specific gene expression program in Hodgkin and Reed-Sternberg cells of Hodgkin lymphoma Blood 101 1505 1512 1:CAS:528:DC%2BD3sXht1agu7k%3D 10.1182/blood-2002-03-0839 12393731 (Pubitemid 36182527)
-
(2003)
Blood
, vol.101
, Issue.4
, pp. 1505-1512
-
-
Schwering, I.1
Brauninger, A.2
Klein, U.3
Jungnickel, B.4
Tinguely, M.5
Diehl, V.6
Hansmann, M.-L.7
Dalla-Favera, R.8
Rajewsky, K.9
Kuppers, R.10
-
31
-
-
8644227858
-
Epigenetic silencing of the immunoglobulin heavy-chain gene in classical Hodgkin lymphoma-derived cell lines contributes to the loss of immunoglobulin expression
-
DOI 10.1182/blood-2003-04-1197
-
A Ushmorov O Ritz M Hummel, et al. 2004 Epigenetic silencing of the immunoglobulin heavy-chain gene in classical Hodgkin lymphoma-derived cell lines contributes to the loss of immunoglobulin expression Blood 104 3326 3334 1:CAS:528:DC%2BD2cXhtVWhurvP 10.1182/blood-2003-04-1197 15284123 (Pubitemid 39507153)
-
(2004)
Blood
, vol.104
, Issue.10
, pp. 3326-3334
-
-
Ushmorov, A.1
Ritz, O.2
Hummel, M.3
Leithauser, F.4
Moller, P.5
Stein, H.6
Wirth, T.7
-
32
-
-
33644765802
-
Epigenetic processes play a major role in B-cell-specific gene silencing in classical Hodgkin lymphoma
-
DOI 10.1182/blood-2005-09-3765
-
A Ushmorov F Leithauser O Sakk, et al. 2006 Epigenetic processes play a major role in B-cell-specific gene silencing in classical Hodgkin lymphoma Blood 107 2493 2500 1:CAS:528:DC%2BD28XisFOju74%3D 10.1182/blood-2005-09-3765 16304050 (Pubitemid 43345573)
-
(2006)
Blood
, vol.107
, Issue.6
, pp. 2493-2500
-
-
Ushmorov, A.1
Leithauser, F.2
Sakk, O.3
Weinhausel, A.4
Popov, S.W.5
Moller, P.6
Wirth, T.7
-
33
-
-
77955430710
-
The Histone Deacetylase (HDAC) Inhibitor Entinostat (SNDX-275) targets Hodgkin Lymphoma through a dual mechanism of immune modulation and apoptosis induction
-
NM Khaskhely D Buglio J Shafer CM Bollard A Younes 2009 The Histone Deacetylase (HDAC) Inhibitor Entinostat (SNDX-275) targets Hodgkin Lymphoma through a dual mechanism of immune modulation and apoptosis induction Blood (ASH Annual Meeting Abstracts) 114 1562
-
(2009)
Blood (ASH Annual Meeting Abstracts)
, vol.114
, pp. 1562
-
-
Khaskhely, N.M.1
Buglio, D.2
Shafer, J.3
Bollard, C.M.4
Younes, A.5
-
34
-
-
77955419796
-
The histone deacetylase inhibitor MGCD0103 down regulates CD30, activates NF-Kb, and synergizes with proteasome inhibitors by HDAC6 independent mechanism in Hodgkin Lymphoma
-
D Buglio V Mamidipudi NM Khaskhely, et al. 2009 The histone deacetylase inhibitor MGCD0103 down regulates CD30, activates NF-Kb, and synergizes with proteasome inhibitors by HDAC6 independent mechanism in Hodgkin Lymphoma Blood (ASH Annual Meeting Abstracts) 114 3735
-
(2009)
Blood (ASH Annual Meeting Abstracts)
, vol.114
, pp. 3735
-
-
Buglio, D.1
Mamidipudi, V.2
Khaskhely, N.M.3
-
35
-
-
51649092609
-
Vorinostat inhibits STAT6-mediated TH2 cytokine and TARC production and induces cell death in Hodgkin lymphoma cell lines
-
1:CAS:528:DC%2BD1cXpvVOktb0%3D 10.1182/blood-2008-01-133769 18541724
-
D Buglio GV Georgiakis S Hanabuchi, et al. 2008 Vorinostat inhibits STAT6-mediated TH2 cytokine and TARC production and induces cell death in Hodgkin lymphoma cell lines Blood 112 1424 1433 1:CAS:528:DC%2BD1cXpvVOktb0%3D 10.1182/blood-2008-01-133769 18541724
-
(2008)
Blood
, vol.112
, pp. 1424-1433
-
-
Buglio, D.1
Georgiakis, G.V.2
Hanabuchi, S.3
-
36
-
-
19944426160
-
+ Hodgkin's disease
-
DOI 10.1084/jem.20040890
-
CM Bollard L Aguilar KC Straathof, et al. 2004 Cytotoxic T lymphocyte therapy for Epstein-Barr virus+ Hodgkin's disease J Exp Med 200 1623 1633 1:CAS:528:DC%2BD2cXhtFGmurbI 10.1084/jem.20040890 15611290 (Pubitemid 40094186)
-
(2004)
Journal of Experimental Medicine
, vol.200
, Issue.12
, pp. 1623-1633
-
-
Bollard, C.M.1
Aguilar, L.2
Straathof, K.C.3
Gahn, B.4
Huls, M.H.5
Rousseau, A.6
Sixbey, J.7
Gresik, M.V.8
Carrum, G.9
Hudson, M.10
Dilloo, D.11
Gee, A.12
Brenner, M.K.13
Rooney, C.M.14
Heslop, H.E.15
-
37
-
-
35549008976
-
Complete responses of relapsed lymphoma following genetic modification of tumor-antigen presenting cells and T-lymphocyte transfer
-
DOI 10.1182/blood-2007-05-091280
-
CM Bollard S Gottschalk AM Leen, et al. 2007 Complete responses of relapsed lymphoma following genetic modification of tumor-antigen presenting cells and T-lymphocyte transfer Blood 110 2838 2845 1:CAS:528:DC%2BD2sXht1SmurfJ 10.1182/blood-2007-05-091280 17609424 (Pubitemid 350006936)
-
(2007)
Blood
, vol.110
, Issue.8
, pp. 2838-2845
-
-
Bollard, C.M.1
Gottschalk, S.2
Leen, A.M.3
Weiss, H.4
Straathof, K.C.5
Carrum, G.6
Khalil, M.7
Wu, M.-F.8
Huls, M.H.9
Chang, C.-C.10
Gresik, M.V.11
Gee, A.P.12
Brenner, M.K.13
Rooney, C.M.14
Heslop, H.E.15
-
38
-
-
0041465971
-
Virally targeted therapies for EBV-associated malignancies
-
DOI 10.1038/sj.onc.1206548
-
BF Israel SC Kenney 2003 Virally targeted therapies for EBV-associated malignancies Oncogene 22 5122 5130 1:CAS:528:DC%2BD3sXmtFahurw%3D 10.1038/sj.onc.1206548 12910249 (Pubitemid 37059593)
-
(2003)
Oncogene
, vol.22
, Issue.33 REV. ISS. 2
, pp. 5122-5130
-
-
Israel, B.F.1
Kenney, S.C.2
-
39
-
-
0842326026
-
Lytic Induction Therapy for Epstein-Barr Virus-Positive B-Cell Lymphomas
-
DOI 10.1128/JVI.78.4.1893-1902.2004
-
WH Feng G Hong HJ Delecluse SC Kenney 2004 Lytic induction therapy for Epstein-Barr virus-positive B-cell lymphomas J Virol 78 1893 1902 1:CAS:528:DC%2BD2cXhtFKnsro%3D 10.1128/JVI.78.4.1893-1902.2004 14747554 (Pubitemid 38176721)
-
(2004)
Journal of Virology
, vol.78
, Issue.4
, pp. 1893-1902
-
-
Feng, W.-H.1
Hong, G.2
Delecluse, H.-J.3
Kenney, S.C.4
-
40
-
-
33749031579
-
Valproic acid enhances the efficacy of chemotherapy in EBV-positive tumors by increasing lytic viral gene expression
-
DOI 10.1158/0008-5472.CAN-06-1006
-
WH Feng SC Kenney 2006 Valproic acid enhances the efficacy of chemotherapy in EBV-positive tumors by increasing lytic viral gene expression Cancer Res 66 8762 8769 1:CAS:528:DC%2BD28XovF2hsLY%3D 10.1158/0008-5472.CAN-06- 1006 16951192 (Pubitemid 44449193)
-
(2006)
Cancer Research
, vol.66
, Issue.17
, pp. 8762-8769
-
-
Feng, W.-H.1
Kenney, S.C.2
-
41
-
-
0034210182
-
Expression of gene MAGE-A4 in Reed-Sternberg cells
-
1:CAS:528:DC%2BD3cXjsl2isb0%3D 10828039
-
H Chambost N Van Baren F Brasseur, et al. 2000 Expression of gene MAGE-A4 in Reed-Sternberg cells Blood 95 3530 3533 1:CAS:528:DC%2BD3cXjsl2isb0%3D 10828039
-
(2000)
Blood
, vol.95
, pp. 3530-3533
-
-
Chambost, H.1
Van Baren, N.2
Brasseur, F.3
-
42
-
-
0036307170
-
Expression of SSX genes in the neoplastic cells of Hodgkin's lymphoma
-
DOI 10.1053/hupa.2002.124909
-
GW Colleoni P Capodieci S Tickoo J Cossman DA Filippa M Ladanyi 2002 Expression of SSX genes in the neoplastic cells of Hodgkin's lymphoma Hum Pathol 33 496 502 1:CAS:528:DC%2BD38XlslCls7g%3D 10.1053/hupa.2002.124909 12094374 (Pubitemid 34747868)
-
(2002)
Human Pathology
, vol.33
, Issue.5
, pp. 496-502
-
-
Colleoni, G.W.B.1
Capodieci, P.2
Tickoo, S.3
Cossman, J.4
Filippa, D.A.5
Ladanyi, M.6
-
43
-
-
0029764293
-
Induction of MAGE genes in lymphoid cells by the demethylating agent 5-aza-2′-deoxycytidine
-
1:CAS:528:DyaK28Xks1ejtL8%3D 8698626
-
S Shichijo A Yamada K Sagawa, et al. 1996 Induction of MAGE genes in lymphoid cells by the demethylating agent 5-aza-2′-deoxycytidine Jpn J Cancer Res 87 751 756 1:CAS:528:DyaK28Xks1ejtL8%3D 8698626
-
(1996)
Jpn J Cancer Res
, vol.87
, pp. 751-756
-
-
Shichijo, S.1
Yamada, A.2
Sagawa, K.3
-
44
-
-
70350451749
-
Expression of histone deacetylases in lymphoma: Implication for the development of selective inhibitors
-
1:CAS:528:DC%2BD1MXhsFKjtbzN 10.1111/j.1365-2141.2009.07887.x 19775297
-
A Gloghini D Buglio NM Khaskhely, et al. 2009 Expression of histone deacetylases in lymphoma: implication for the development of selective inhibitors Br J Haematol 147 515 525 1:CAS:528:DC%2BD1MXhsFKjtbzN 10.1111/j.1365-2141.2009.07887.x 19775297
-
(2009)
Br J Haematol
, vol.147
, pp. 515-525
-
-
Gloghini, A.1
Buglio, D.2
Khaskhely, N.M.3
-
45
-
-
51649092609
-
Vorinostat inhibits STAT6-mediated TH2 cytokine and TARC production and induces cell death in Hodgkin lymphoma cell lines
-
1:CAS:528:DC%2BD1cXpvVOktb0%3D 10.1182/blood-2008-01-133769 18541724
-
D Buglio GV Georgakis S Hanabuchi, et al. 2008 Vorinostat inhibits STAT6-mediated TH2 cytokine and TARC production and induces cell death in Hodgkin lymphoma cell lines Blood 112 1424 1433 1:CAS:528:DC%2BD1cXpvVOktb0%3D 10.1182/blood-2008-01-133769 18541724
-
(2008)
Blood
, vol.112
, pp. 1424-1433
-
-
Buglio, D.1
Georgakis, G.V.2
Hanabuchi, S.3
-
46
-
-
42249084230
-
MGCD0103, a novel isotype-selective histone deacetylase inhibitor, has broad spectrum antitumor activity in vitro and in vivo
-
DOI 10.1158/1535-7163.MCT-07-2026
-
M Fournel C Bonfils Y Hou, et al. 2008 MGCD0103, a novel isotype-selective histone deacetylase inhibitor, has broad spectrum antitumor activity in vitro and in vivo Mol Cancer Ther 7 759 768 1:CAS:528: DC%2BD1cXks1Gms70%3D 10.1158/1535-7163.MCT-07-2026 18413790 (Pubitemid 351551029)
-
(2008)
Molecular Cancer Therapeutics
, vol.7
, Issue.4
, pp. 759-768
-
-
Fournel, M.1
Bonfils, C.2
Hou, Y.3
Yan, P.T.4
Trachy-Bourget, M.-C.5
Kalita, A.6
Liu, J.7
Lu, A.-H.8
Zhou, N.Z.9
Robert, M.-F.10
Gillespie, J.11
Wang, J.J.12
Ste-Croix, H.13
Rahil, J.14
Lefebvre, S.15
Moradei, O.16
Delorme, D.17
MacLeod, A.R.18
Besterman, J.M.19
Li, Z.20
more..
-
47
-
-
77955414281
-
Clinical development of MGCD0103, an isotype-selective HDAC inhibitor: Pericarditis/pericardial effusion in the context of overall safety and efficacy
-
RE Martell G Garcia-Manero A Younes, et al. 2009 Clinical development of MGCD0103, an isotype-selective HDAC inhibitor: pericarditis/pericardial effusion in the context of overall safety and efficacy Blood (ASH Annual Meeting Abstracts) 114 4756
-
(2009)
Blood (ASH Annual Meeting Abstracts)
, vol.114
, pp. 4756
-
-
Martell, R.E.1
Garcia-Manero, G.2
Younes, A.3
-
48
-
-
77955417430
-
Efficacy of panobinostat in phase II study in patients with relapsed/refractory Hodgkin Lymphoma (HL) after high-dose chemotherapy with autologous stem cell transplant
-
A Younes T-C Ong V Ribrag, et al. 2009 Efficacy of panobinostat in phase II study in patients with relapsed/refractory Hodgkin Lymphoma (HL) after high-dose chemotherapy with autologous stem cell transplant Blood (ASH Annual Meeting Abstracts) 114 923
-
(2009)
Blood (ASH Annual Meeting Abstracts)
, vol.114
, pp. 923
-
-
Younes, A.1
Ong, T.-C.2
Ribrag, V.3
-
49
-
-
67651160018
-
Phase II study of the histone-deacetylase inhibitor ITF2357 in relapsed/refractory Hodgkin's lymphoma patients
-
S Viviani V Bonfante C Fasola P Valagussa AM Gianni 2008 Phase II study of the histone-deacetylase inhibitor ITF2357 in relapsed/refractory Hodgkin's lymphoma patients ASCO Meeting Abstracts 26 8532
-
(2008)
ASCO Meeting Abstracts
, vol.26
, pp. 8532
-
-
Viviani, S.1
Bonfante, V.2
Fasola, C.3
Valagussa, P.4
Gianni, A.M.5
-
50
-
-
77955139453
-
Phase II trial of combination of the histone deacetylase inhibitor ITF2357 and meclorethamine demonstrates clinical activity and safety in heavily pretreated patients with relapsed/refractory Hodgkin Lymphoma (HL)
-
C Carlo-Stella A Guidetti S Viviani, et al. 2008 Phase II trial of combination of the histone deacetylase inhibitor ITF2357 and meclorethamine demonstrates clinical activity and safety in heavily pretreated patients with relapsed/refractory Hodgkin Lymphoma (HL) Blood (ASH Annual Meeting Abstracts) 112 2586
-
(2008)
Blood (ASH Annual Meeting Abstracts)
, vol.112
, pp. 2586
-
-
Carlo-Stella, C.1
Guidetti, A.2
Viviani, S.3
-
51
-
-
54249117966
-
Oral panobinostat (LBH589), a novel deacetylase inhibitor (DACi) demonstrates clinical activity in relapsed/refractory Hodgkin lymphoma (HL)
-
10.1093/annonc/mdn329 Abstract
-
A Spencer DJ DeAngelo HM Prince, et al. 2008 Oral panobinostat (LBH589), a novel deacetylase inhibitor (DACi) demonstrates clinical activity in relapsed/refractory Hodgkin lymphoma (HL) Ann Oncol 19 136 10.1093/annonc/mdn329 Abstract
-
(2008)
Ann Oncol
, vol.19
, pp. 136
-
-
Spencer, A.1
Deangelo, D.J.2
Prince, H.M.3
|