Glycosylation of a disintegrin and metalloprotease 17 affects its activity and inhibition

Analytical Biochemistry

Volumn 449, Issue 1, 2014, Pages 68-75

  Chavaroche, Anais ^a   Cudic, Mare ^a   Giulianotti, Marc ^a   Houghten, Richard A ^a   Fields, Gregg B ^a   Minond, Dmitriy ^a  

^a TORREY PINES INSTITUTE FOR MOLECULAR STUDIES   (United States)

Author keywords

ADAM17; Exosites; Glycosylation; Metalloprotease

Indexed keywords

CELL SIGNALING; CELLS; CYTOLOGY; DISEASES; ENZYME ACTIVITY; MAMMALS; SUBSTRATES; ZINC;

ADAM17; ENZYMATIC ACTIVITIES; EXOSITES; INHIBITION PROFILE; METALLO-PROTEASE; RHEUMATOID ARTHRITIS; SUBSTRATE KINETICS; THERAPEUTIC INTERVENTION;

GLYCOSYLATION;

A DISINTEGRIN AND METALLOPROTEASE 17; ADAM PROTEIN; UNCLASSIFIED DRUG;

ARTICLE; ENZYME ACTIVITY; ENZYME GLYCOSYLATION; ENZYME INHIBITION; ENZYME KINETICS; INSECT CELL; MAMMAL CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION;

ADAM17; EXOSITES; GLYCOSYLATION; METALLOPROTEASE;

ADAM PROTEINS; AMINO ACID SEQUENCE; ANIMALS; CLONING, MOLECULAR; ENZYME ACTIVATION; ENZYME INHIBITORS; GLYCOSYLATION; HEK293 CELLS; HUMANS; KINETICS; MOLECULAR SEQUENCE DATA; RECOMBINANT PROTEINS;

EID: 84892765332     PISSN: 00032697     EISSN: 10960309     Source Type: Journal    
DOI: 10.1016/j.ab.2013.12.018     Document Type: Article

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