DNA damage in peripheral blood lymphocytes from patients with OSAHS

Sleep and Breathing

Volumn 18, Issue 4, 2014, Pages 775-780

  Xie, Jing ^a   Jiang, Jianzhong ^a   Shi, Keyun ^a   Zhang, Tingting ^a   Zhu, Taofeng ^a   Chen, Hong ^a   Chen, Ruhua ^a   Qi, Liming ^a   Ding, Weiliang ^a   Yi, Qiyi ^b   Ma, Tieliang ^a  

^a YIXING PEOPLE S HOSPITAL   (China)

^b ANHUI MEDICAL UNIVERSITY   (China)

Author keywords

DNA damage; Micronuclei; Nasal continuous positive airway pressure; Obstructive sleep apnea hypopnea syndrome; Oxidative stress

Indexed keywords

EID: 84892738112     PISSN: 15209512     EISSN: 15221709     Source Type: Journal    
DOI: 10.1007/s11325-014-0942-8     Document Type: Article

References (38)

1. Moura SM, Bittencourt LR, Bagnato MC, Lucas SR, Tufik S, Nery LE (2001) Acute effect of nasal continuous positive air pressure on the ventilatory control of patients with obstructive sleep apnea. Respiration 68(3):243–249
2. Editorial Board of Chinese Journal of Otorhinolaryngology Head and Neck Surgery; Chinese Otorhinolaryngology of Chinese Medical Association (2007) Draft of guidelines for the diagnosis and treatment of pediatric sleep apnea hypopnea syndrome (Urumqi). Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi 42(2):83–84
3. Christou K, Moulas AN, Pastaka C, Gourgoulianis KI (2003) Antioxidant capacity in obstructive sleep apnea patients. Sleep Med 4(3):225–228
4. Redline S, Tosteson T, Tishler PV, Carskadon MA, Millman RP (1992) Studies in the genetics of obstructive sleep apnea. Familial aggregation of symptoms associated with sleep-related breathing disturbances. Am Rev Respir Dis 145(2 Pt 1):440–444
5. Büchner NJ, Quack I, Woznowski M, Stähle C, Wenzel U, Rump LC (2011) Microvascular endothelial dysfunction in obstructive sleep apnea is caused by oxidative stress and improved by continuous positive airway pressure therapy. Respiration 82(5):409–417
6. Møller P, Loft S, Lundby C, Olsen NV (2001) Acute hypoxia and hypoxic exercise induce DNA strand breaks and oxidative DNA damage in humans. FASEB J 15(7):1181–1186
7. Fenech M (2007) Cytokinesis-block micronucleus cytome assay. Nat Protoc 2(5):1084–1104
8. Fenech M (2006) Cytokinesis-block micronucleus assay evolves into a “cytome” assay of chromosomal instability, mitotic dysfunction and cell death. Mutat Res 600(1–2):58–66
9. Umegaki K, Fenech M (2000) Cytokinesis-block micronucleus assay in WIL2-NS cells: a sensitive system to detect chromosomal damage induced by reactive oxygen species and activated human neutrophils. Mutagenesis 15(3):261–269
10. Thomas P, Umegaki K, Fenech M (2003) Nucleoplasmic bridges are a sensitive measure of chromosome rearrangement in the cytokinesis-block micronucleus assay. Mutagenesis 18(2):187–194
11. Kontogianni K, Messini-Nikolaki N, Christou K, Gourgoulianis K, Tsilimigaki S, Piperakis SM (2007) DNA damage and repair capacity in lymphocytes from obstructive sleep apnea patients. Environ Mol Mutagen 48(9):722–727
12. Fenech M (2000) The in vitro micronucleus technique. Mutat Res 455(1–2):81–95
13. Fenech M, Morley A (1985) Solutions to the kinetic problem in the micronucleus assay. Cytobios 43(172–173):233–246
14. Fenech M, Morley AA (1985) Measurement of micronuclei in lymphocytes. Mutat Res 147(1–2):29–36
15. Pepperell JC, Ramdassingh-Dow S, Crosthwaite N, Mullins R, Jenkinson C, Stradling JR, Davies RJ (2002) Ambulatory blood pressure after therapeutic and subtherapeutic nasal continuous positive airway pressure for obstructive sleep apnoea: a randomised parallel trial. Lancet 359(9302):204–210
16. Becker HF, Jerrentrup A, Ploch T, Grote L, Penzel T, Sullivan CE, Peter JH (2003) Effect of nasal continuous positive airway pressure treatment on blood pressure in patients with obstructive sleep apnea. Circulation 107(1):68–73
17. Mason RH, Kiire CA, Groves DC, Lipinski HJ, Jaycock A, Winter BC, Smith L, Bolton A, Rahman NM, Swaminathan R, Chong VN, Stradling JR (2012) Visual improvement following continuous positive airway pressure therapy in diabetic subjects with clinically significant macular oedema and obstructive sleep apnoea: proof of principle study. Respiration 84(4):275–282
18. Yamauchi M, Kimura H (2008) Oxidative stress in obstructive sleep apnea: putative pathways to the cardiovascular complications. Antioxid Redox Signal 10(4):755–768
19. Jordan W, Cohrs S, Degner D, Meier A, Rodenbeck A, Mayer G, Pilz J, Rüther E, Kornhuber J, Bleich S (2006) Evaluation of oxidative stress measurements in obstructive sleep apnea syndrome. J Neural Transm 113(2):239–254
20. Lavie L, Lavie P (2009) Molecular mechanisms of cardiovascular disease in OSAHS: the oxidative stress link. Eur Respir J 33(6):1467–1484
21. Gajski G, Gerić M, Oreščanin V, Garaj-Vrhovac V (2013) Cytogenetic status of healthy children assessed with the alkaline comet assay and the cytokinesis-block micronucleus cytome assay. Mutat Res 750(1–2):55–62
22. Tafazoli M, Volders MK (1996) In vitro mutagenicity and genotoxicity study of 1,2-dichloroethylene, 1,1,2-trichloroethylene, 1,3-dichloropropane, 1,2,3-trichloropropane and 1,1,3-trichloropropane, using the micronucleus test and the alkaline single cell gel electrophoresis technique (comet assay) in human lymphocytes. Mutat Res 371:185–202
23. Goethem FV, Lison D, Volders MK (1997) Comparative evaluation of the in vitro micronucleus test and the alkaline single cell gel electrophoresis assay for the detection of DNA damaging agent: Genotoxic effects of cobalt powder, tungsten carbide and cobalt-tungsten carbide. Mutat Res 392:31–43
24. He JL, Chen WL, Jin LF, Jin HY (2000) Comparative evaluation of the in vitro micronucleus test and the comet assay for the detection of genotoxic effects of x-ray radiation. Mutat Res 469:223–231
25. Severin I, Dumont C, Jondeau-Cabaton A, Graillot V, Chagnon MC (2010) Genotoxic activities of the food contaminant 5-hydroxymethylfurfural using different in vitro bioassays. Toxicol Lett 192:189–194
26. Maluf SW, Mergener M, Dalcanale L, Costa CC, Pollo T, Kayser M, da Silva LB, Pra D, Teixeira PJ (2007) DNA damage in peripheral blood of patients with chronic obstructive pulmonary disease (COPD). Mutat Res 626(1–2):180–184
27. Rao X, Zhang Y, Yi Q, Hou H, Xu B, Chu L, Huang Y, Zhang W, Fenech M, Shi Q (2008) Multiple origins of spontaneously arising micronuclei in HeLa cells: direct evidence from long-term live cell imaging. Mutat Res 646(1–2):41–49
28. Hoffelder DR, Luo L, Burke NA, Watkins SC, Gollin SM, Saunders WS (2004) Resolution of anaphase bridges in cancer cells. Chromosoma 112(8):389–397
29. Shimizu N, Shingaki K, Kaneko-Sasaguri Y, Hashizume T, Kanda T (2005) When, where and how the bridge breaks: anaphase bridge breakage plays a crucial role in gene amplification and HSR generation. Exp Cell Res 302(2):233–243
30. Choi KM, Kang CM, Cho ES, Kang SM, Lee SB, Um HD (2007) Ionizing radiation-induced micronucleus formation is mediated by reactive oxygen species that are produced in a manner dependent on mitochondria, Nox1 and JNK. Oncol Rep 17(5):1183–1188
31. Lavie L, Vishnevsky A, Lavie P (2004) Evidence for lipid peroxidation in obstructive sleep apnea. Sleep 27(1):123–128
32. Jelic S, Padeletti M, Kawut SM, Higgins C, Canfield SM, Onat D, Colombo PC, Basner RC, Factor P, LeJemtel TH (2008) Inflammation, oxidative stress, and repair capacity of the vascular endothelium in obstructive sleep apnea. Circulation 117:2270–2278
33. Karamanlı H, Ozol D, Ugur KS, Yıldırım Z, Armutçu F, Bozkurt B, Yigitoglu R (2012) Influence of CPAP treatment on airway and systemic inflammation in OSAS patients. Sleep Breath 06:45
34. Jurado-Gamez B, Gomez-Chaparro JL, Muñoz-Calero M, Serna Sanz A, Muñoz-Cabrera L, Lopez-Barea J, Gozal D (2012) Serum proteomic changes in adults with obstructive sleep apnoea. J Sleep Res 21(2):139–146
35. Dyugovskaya L, Lavie P, Lavie L (2002) Increased adhesion molecules expression and production of reactive oxygen species in leukocytes of sleep apnea patients. Am J Respir Crit Care Med 165(7):934–939
36. Rahman I (2003) Oxidative stress, chromatin remodeling and gene transcription in inflammation and chronic lung diseases. J Biochem Mol Biol 36(1):95–109
37. Hernandez C, Abreu J, Abreu P, Colino R, Jimenez A (2006) Effects of nasal positive airway pressure treatment on oxidative stress in patients with sleep apnea hypopnea syndrome. Arch Bronconeumol 42:125–129
38. Svatikova A, Wolk R, Lerman LO, Juncos LA, Greene EL, McConnell JP, Somers VK (2005) Oxidative stress in obstructive sleep apnoea. Eur Heart J 26(22):2435–2439