Targeted transgene integration overcomes variability of position effects in zebrafish

Development (Cambridge)

Volumn 141, Issue 3, 2014, Pages 715-724

  Roberts, Jennifer Anne ^a   Miguel Escalada, Irene ^a   Slovik, Katherine Joan ^b   Walsh, Kathleen Theodora ^b   Hadzhiev, Yavor ^a   Sanges, Remo ^c   Stupka, Elia ^d   Marsh, Elizabeth Kate ^a   Balciuniene, Jorune ^b   Balciunas, Darius ^b   Müller, Ferenc ^a  

^a UNIVERSITY OF BIRMINGHAM   (United Kingdom)

^b Temple University   (United States)

^c STAZIONE ZOOLOGICA ANTON DOHRN   (Italy)

^d SAN RAFFAELE HOSPITAL   (Italy)

Author keywords

Enhancer; Integrase; Position effects; Tol2; Transgenesis; Zebrafish

Indexed keywords

INTEGRASE; MESSENGER RNA; SPACER DNA;

3' UNTRANSLATED REGION; ANIMAL CELL; ARTICLE; BRAIN NUCLEUS; EMBRYO; ENHANCER REGION; EYE COLOR; GENE ACTIVITY; GENE EXPRESSION; GENE TARGETING; GENETIC VARIABILITY; MOSAICISM; MUTAGENICITY; NONHUMAN; PHENOTYPE; POSITION EFFECT; PRIMORDIAL GERM CELL; PRIORITY JOURNAL; REPORTER GENE; TISSUE SPECIFICITY; TRANSGENE; TRANSGENICS; ZEBRA FISH;

ENHANCER; INTEGRASE; POSITION EFFECTS; TOL2; TRANSGENESIS; ZEBRAFISH;

ANIMALS; ANIMALS, GENETICALLY MODIFIED; BASE SEQUENCE; BRAIN; CHROMOSOMAL POSITION EFFECTS; ENHANCER ELEMENTS, GENETIC; GENE EXPRESSION REGULATION; GENE TARGETING; GENE TRANSFER TECHNIQUES; GENES, REPORTER; GENETIC LOCI; GENOME; INTEGRASES; LENS, CRYSTALLINE; MOLECULAR SEQUENCE DATA; MUTAGENESIS, INSERTIONAL; REPRODUCIBILITY OF RESULTS; TRANSGENES; XENOPUS LAEVIS; ZEBRAFISH;

EID: 84892730257     PISSN: 09501991     EISSN: 14779129     Source Type: Journal    
DOI: 10.1242/dev.100347     Document Type: Article

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